Faculty profile

Pierre Lachapelle

ResearcherMedical GeneticsMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Pierre Lachapelle

Researcher

Medical Genetics

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
4 publications in the last five years, latest in 2025.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 6 research grants (5 CIHR, 1 NSERC), most recently in 2016.
Supervised 1 trainee who won CIHR awards, most recently in 2012.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Clinical Trial Endpoints Drug Treatment Mouse Models Natural History Studies Orphan Diseases Peroxisome Diseases Peroxisome Metabolic Pathways Retinal Degeneration

Latest papers

Hilbert transform analysis of the mouse scotopic electroretinogram reveals two distinct bursts of oscillatory potentials with progressively dimmer flashes.
Documenta ophthalmologica. Advances in ophthalmology · 2025 · senior author
Endoplasmic Reticulum Stress Delays Choroid Development in the HCAR1 Knockout Mouse.
The American journal of pathology · 2024
Comparing the RETeval® portable ERG device with more traditional tabletop ERG systems in normal subjects and selected retinopathies.
Documenta ophthalmologica. Advances in ophthalmology · 2023 · senior author

All 61 publications

Latest funding

Getting Ready for Vision Therapy in Peroxisome Biogenesis Disorders
CIHR · 2016 · Principal investigator
$959,310
Retinitis Pigmentosa diagnosis and therapy: retinal remodeling and optogenetic reactivation of degenerated retina
CIHR · 2013 · Nominated PI
$259,441
Brain and eyes in asphyxiated newborns: common ground for disease development and common novel target for treatment?
CIHR · 2013 · Principal investigator
$441,372

All 7 grants and awards

61 publications.

Hilbert transform analysis of the mouse scotopic electroretinogram reveals two distinct bursts of oscillatory potentials with progressively dimmer flashes.

Gauthier M, Polosa A, Lina JM, Lachapelle P

Documenta ophthalmologica. Advances in ophthalmology2025Senior author

DOI: 10.1007/s10633-025-10002-9 PMID: 39875716

Endoplasmic Reticulum Stress Delays Choroid Development in the HCAR1 Knockout Mouse.

Modaresinejad M, Yang X, Mohammad Nezhady MA, Zhu T, Bajon E, Hou X, Tahiri H, Hardy P, Rivera JC, Lachapelle P, Chemtob S

The American journal of pathology2024

DOI: 10.1016/j.ajpath.2024.09.002 PMID: 39332673

Comparing the RETeval® portable ERG device with more traditional tabletop ERG systems in normal subjects and selected retinopathies.

You JY, Dorfman AL, Gauvin M, Vatcher D, Polomeno RC, Little JM, Lachapelle P

Documenta ophthalmologica. Advances in ophthalmology2023Senior author

DOI: 10.1007/s10633-022-09903-w PMID: 36273363

Resting state electroretinography: An innovative approach to intrinsic retinal function monitoring.

Gauthier M, Simard AB, Polosa A, Dorfman AL, Qian CX, Lina JM, Lachapelle P

Frontiers in physiology2022Senior author

DOI: 10.3389/fphys.2022.931147 PMID: 36091360

AAV-mediated PEX1 gene augmentation improves visual function in the PEX1-Gly844Asp mouse model for mild Zellweger spectrum disorder.

Argyriou C, Polosa A, Song JY, Omri S, Steele B, Cécyre B, McDougald DS, Di Pietro E, Bouchard JF, Bennett J, Hacia JG, Lachapelle P, Braverman NE

Molecular therapy. Methods & clinical development2021

DOI: 10.1016/j.omtm.2021.09.002 PMID: 34703844

Organic visual loss measured by kinetic perimetry and retinal electrophysiology in children with functional amblyopia.

Beneish R, Dorfman AL, Khan A, Polomeno RC, Lachapelle P

Documenta ophthalmologica. Advances in ophthalmology2021Senior author

DOI: 10.1007/s10633-020-09811-x PMID: 33515394

Functional alterations of retinal neurons and vascular involvement progress simultaneously in the Psammomys obesus model of diabetic retinopathy.

Dellaa A, Mbarek S, Kahloun R, Dogui M, Khairallah M, Hammoum I, Rayana-Chekir NB, Charfeddine R, Lachapelle P, Chaouacha-Chekir RB

The Journal of comparative neurology2021

DOI: 10.1002/cne.25114 PMID: 33474721

Ring analysis of multifocal oscillatory potentials (mfOPs) in cCSNB suggests near-normal ON-OFF pathways at the fovea only.

Dorfman AL, Gauvin M, Vatcher D, Little JM, Polomeno RC, Lachapelle P

Documenta ophthalmologica. Advances in ophthalmology2020Senior author

DOI: 10.1007/s10633-020-09755-2 PMID: 32060756

Distinguishing Familial from Acquired Traits in the Retinal Blood Vessel Arborization.

Bouthillier A, Berthiaume LF, Nguyen AX, Zhai SY, Lalla S, Bédard O, Gauvin M, Little JM, Lachapelle P

Translational vision science & technology2020Senior author

DOI: 10.1167/tvst.9.8.27 PMID: 32855873

Snap29 mutant mice recapitulate neurological and ophthalmological abnormalities associated with 22q11 and CEDNIK syndrome.

Keser V, Lachance JB, Alam SS, Lim Y, Scarlata E, Kaur A, Zhang TF, Lv S, Lachapelle P, O'Flaherty C, Golden JA, Jerome-Majewska LA

Communications biology2019

DOI: 10.1038/s42003-019-0601-5 PMID: 31633066

Getting Ready for Vision Therapy in Peroxisome Biogenesis Disorders

Principal investigatorCIHR2016Project Grant

Principal investigators: Braverman, Nancy E; Koenekoop, Robert K; Lachapelle, Pierre

Keywords: Clinical Trial Endpoints; Drug Treatment; Mouse Models; Natural History Studies; Orphan Diseases; Peroxisome Diseases; Peroxisome Metabolic Pathways; Retinal Degeneration

$959,310

Retinitis Pigmentosa diagnosis and therapy: retinal remodeling and optogenetic reactivation of degenerated retina

Nominated PICIHR2013Operating Grant - E-Rare-2 Joint Transnational Call on Rare Diseases

Principal investigators: Lachapelle, Pierre

Keywords: Blindness; Optogenetic; Photoreceptor; Plasticity; Retina; Retinitis Pigmentosa; Therapy

$259,441

Brain and eyes in asphyxiated newborns: common ground for disease development and common novel target for treatment?

Principal investigatorCIHR2013Operating Grant

Principal investigators: Wintermark, Pia; Lachapelle, Pierre

Keywords: Asphyxia; Brain; Eyes; Newborn; Treatment

$441,372

Impact of neonatal hypoxic-ischemic encephalopathy on eyes and vision

SupervisorCIHR2012Master's Award: Canada Graduate Scholarships

Principal investigators: Jung, Suna

Keywords: Brain; Electroretinography; Histology; Hypoxic-Ischemic Encephalopathy; Newborn; Perinatal Asphyxia; Retina; Vision; Visual System; Visually Evoked Potential

$17,500

Diagnosis, prognosis and classification of retinopathies: Comparing time-amplitude domain (TAD) with time-frequency domain (TFD) analyses of the electroretinogram.

Nominated PICIHR2012Operating Grant

Principal investigators: Lachapelle, Pierre

Keywords: Animal Models; Electroretinogram; Erg Model; Human; Mathematical Models; Residual Vision; Retinopathy; Time-Scale Analysis; Visiual Function

$450,863

Evidence suggesting a retinal reorganization in the juvenile rat model of light-induced retinopathy (LIR)

Principal investigatorNSERC2009Discovery Grants Program - Individual

Principal investigators: Lachapelle, Pierre

$150,000

CIHR team on assessment of residual retinal function

Nominated PICIHR2009Team Grant: Vision, Hearing and Communication Disorders - LOI

Principal investigators: Lachapelle, Pierre; Casanova, Christian F; Hebert, Marc; Lina, Jean-Marc

Keywords: Animal Models; Electroretinogram; Erg Model; Human; Mathematical Models; Residual Vision; Retinopathy; Time-Scale Analysis; Visual Function

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Pierre Lachapelle

Research

Latest papers

Latest funding

Hilbert transform analysis of the mouse scotopic electroretinogram reveals two distinct bursts of oscillatory potentials with progressively dimmer flashes.

Endoplasmic Reticulum Stress Delays Choroid Development in the HCAR1 Knockout Mouse.

Comparing the RETeval® portable ERG device with more traditional tabletop ERG systems in normal subjects and selected retinopathies.

Resting state electroretinography: An innovative approach to intrinsic retinal function monitoring.

AAV-mediated PEX1 gene augmentation improves visual function in the PEX1-Gly844Asp mouse model for mild Zellweger spectrum disorder.

Organic visual loss measured by kinetic perimetry and retinal electrophysiology in children with functional amblyopia.

Functional alterations of retinal neurons and vascular involvement progress simultaneously in the Psammomys obesus model of diabetic retinopathy.

Ring analysis of multifocal oscillatory potentials (mfOPs) in cCSNB suggests near-normal ON-OFF pathways at the fovea only.

Distinguishing Familial from Acquired Traits in the Retinal Blood Vessel Arborization.

Snap29 mutant mice recapitulate neurological and ophthalmological abnormalities associated with 22q11 and CEDNIK syndrome.

Getting Ready for Vision Therapy in Peroxisome Biogenesis Disorders

Retinitis Pigmentosa diagnosis and therapy: retinal remodeling and optogenetic reactivation of degenerated retina

Brain and eyes in asphyxiated newborns: common ground for disease development and common novel target for treatment?

Impact of neonatal hypoxic-ischemic encephalopathy on eyes and vision

Diagnosis, prognosis and classification of retinopathies: Comparing time-amplitude domain (TAD) with time-frequency domain (TFD) analyses of the electroretinogram.

Evidence suggesting a retinal reorganization in the juvenile rat model of light-induced retinopathy (LIR)

CIHR team on assessment of residual retinal function

Frequent collaborators

Sylvain Chemtob

Pierre Hardy

Przemyslaw Sapieha

Przemyslaw Sapieha

Sophie Tremblay

Adriana Di Polo

Pia Wintermark

Christian Casanova

Rima Rozen

Gilles Hickson

Jean-Claude Lavoie

Nancy Braverman

Paul Khairy

Santiago Costantino

Cristian O'Flaherty

Santiago Costantino

Gregor Andelfinger

William Lubell

Pierre Lachapelle

Research

Latest papers

Latest funding

Hilbert transform analysis of the mouse scotopic electroretinogram reveals two distinct bursts of oscillatory potentials with progressively dimmer flashes.

Endoplasmic Reticulum Stress Delays Choroid Development in the HCAR1 Knockout Mouse.

Comparing the RETeval&#xae; portable ERG device with more traditional tabletop ERG systems in normal subjects and selected retinopathies.

Resting state electroretinography: An innovative approach to intrinsic retinal function monitoring.

AAV-mediated PEX1 gene augmentation improves visual function in the PEX1-Gly844Asp mouse model for mild Zellweger spectrum disorder.

Organic visual loss measured by kinetic perimetry and retinal electrophysiology in children with functional amblyopia.

Functional alterations of retinal neurons and vascular involvement progress simultaneously in the Psammomys obesus model of diabetic retinopathy.

Ring analysis of multifocal oscillatory potentials (mfOPs) in cCSNB suggests near-normal ON-OFF pathways at the fovea only.

Distinguishing Familial from Acquired Traits in the Retinal Blood Vessel Arborization.

Snap29 mutant mice recapitulate neurological and ophthalmological abnormalities associated with 22q11 and CEDNIK syndrome.

Getting Ready for Vision Therapy in Peroxisome Biogenesis Disorders

Retinitis Pigmentosa diagnosis and therapy: retinal remodeling and optogenetic reactivation of degenerated retina

Brain and eyes in asphyxiated newborns: common ground for disease development and common novel target for treatment?

Impact of neonatal hypoxic-ischemic encephalopathy on eyes and vision

Diagnosis, prognosis and classification of retinopathies: Comparing time-amplitude domain (TAD) with time-frequency domain (TFD) analyses of the electroretinogram.

Evidence suggesting a retinal reorganization in the juvenile rat model of light-induced retinopathy (LIR)

CIHR team on assessment of residual retinal function

Frequent collaborators

Sylvain Chemtob

Pierre Hardy

Przemyslaw Sapieha

Przemyslaw Sapieha

Sophie Tremblay

Adriana Di Polo

Pia Wintermark

Christian Casanova

Rima Rozen

Gilles Hickson

Jean-Claude Lavoie

Nancy Braverman

Paul Khairy

Santiago Costantino

Cristian O'Flaherty

Santiago Costantino

Gregor Andelfinger

William Lubell

Comparing the RETeval® portable ERG device with more traditional tabletop ERG systems in normal subjects and selected retinopathies.