Faculty profile

Claude Perreault

ResearcherInstitut de recherche en immunologie et cancerUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Claude Perreault

Researcher

Institut de recherche en immunologie et cancer

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
17 publications in the last five years, latest in 2026.
Senior (last) author on 11 recent papers, a sign of leading a research group.
Principal investigator on 9 research grants (9 CIHR), most recently in 2023.
Supervised 10 trainees who won CIHR awards, most recently in 2017.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Major Histocompatibility Complex Mass Spectrometry Thymus Transcriptome Sequencing Autoimmunity Mouse Models Chemogenomic Vulnerability Immunopeptidome

Latest papers

Noncanonical Transcription and Splicing Shape the Colorectal Cancer Immunopeptidome in MSI and MSS Tumors.
Molecular & cellular proteomics : MCP · 2026
The cryptic immunopeptidome in health and disease.
Trends in genetics : TIG · 2025 · senior author
CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling.
Cell reports · 2025

All 88 publications

Latest funding

Uncovering tumor specific antigens and vulnerabilities in ETP-acute lymphoblastic leukemia
CIHR · 2023 · Principal investigator
$856,800
Immunotherapeutic Targeting of the U1 snRNA Mutation in Cancer
CIHR · 2020 · Co-investigator
$1,013,626
The proteogenomic landscape of tumour-specific antigens present in triplenegative breast cancers
CIHR · 2018 · Nominated PI
$67,000

All 23 grants and awards

88 publications.

Noncanonical Transcription and Splicing Shape the Colorectal Cancer Immunopeptidome in MSI and MSS Tumors.

Courcelles M, Hardy MP, Durette C, Lanoix J, Minati R, Laverdure JP, Vincent K, Perreault C, Thibault P

Molecular & cellular proteomics : MCP2026

DOI: 10.1016/j.mcpro.2026.101581 PMID: 42106149

The cryptic immunopeptidome in health and disease.

Kina E, Larouche JD, Thibault P, Perreault C

Trends in genetics : TIG2025Senior author

DOI: 10.1016/j.tig.2024.09.003 PMID: 39389870

CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling.

Minati R, Cahuzac M, Perrault J, Lullier V, Apavaloaei A, Bonneil E, Courcelles M, Lanoix J, Kina E, Perreault C, Thibault P

Cell reports2025

DOI: 10.1016/j.celrep.2025.116676 PMID: 41391145

Tumor antigens preferentially derive from unmutated genomic sequences in melanoma and non-small cell lung cancer.

Apavaloaei A, Zhao Q, Hesnard L, Cahuzac M, Durette C, Larouche JD, Hardy MP, Vincent K, Brochu S, Laverdure JP, Lanoix J, Courcelles M, Gendron P, Lajoie M, Ruiz Cuevas MV, Kina E, Perrault J, Humeau J, Ehx G, Lemieux S, Watson IR, Speiser DE, Bassani-Sternberg M, Thibault P, Perreault C

Nature cancer2025Senior author

DOI: 10.1038/s43018-025-00979-2 PMID: 40405018

Immunogenicity of Non-Mutated Ovarian Cancer-Specific Antigens.

Hesnard L, Thériault C, Cahuzac M, Durette C, Vincent K, Hardy MP, Lanoix J, Lavallée GO, Humeau J, Thibault P, Perreault C

Current oncology (Toronto, Ont.)2024Senior author

DOI: 10.3390/curroncol31060236 PMID: 38920720

Autophagy degrades immunogenic endogenous retroelements induced by 5-azacytidine in acute myeloid leukemia.

Noronha N, Durette C, Cahuzac M, E Silva B, Courtois J, Humeau J, Sauvat A, Hardy MP, Vincent K, Laverdure JP, Lanoix J, Baron F, Thibault P, Perreault C, Ehx G

Leukemia2024

DOI: 10.1038/s41375-024-02250-6 PMID: 38627586

Transposable elements regulate thymus development and function.

Larouche JD, Laumont CM, Trofimov A, Vincent K, Hesnard L, Brochu S, Côté C, Humeau JF, Bonneil É, Lanoix J, Durette C, Gendron P, Laverdure JP, Richie ER, Lemieux S, Thibault P, Perreault C

eLife2024Senior author

DOI: 10.7554/elife.91037 PMID: 38635416

Breast cancer immunopeptidomes contain numerous shared tumor antigens.

Kina E, Laverdure JP, Durette C, Lanoix J, Courcelles M, Zhao Q, Apavaloaei A, Larouche JD, Hardy MP, Vincent K, Gendron P, Hesnard L, Thériault C, Ruiz Cuevas MV, Ehx G, Thibault P, Perreault C

The Journal of clinical investigation2024Senior author

DOI: 10.1172/jci166740 PMID: 37906288

Immunotargeting of a recurrent AML-specific neoantigen.

Apavaloaei A, Perreault C

Nature cancer2023Senior author

DOI: 10.1038/s43018-023-00634-8 PMID: 37783806

Introduction to the Special Issue: The Immunopeptidome.

Caron É, Perreault C

Seminars in immunology2023Senior author

DOI: 10.1016/j.smim.2023.101798 PMID: 37348326

Uncovering tumor specific antigens and vulnerabilities in ETP-acute lymphoblastic leukemia

Principal investigatorCIHR2023Project Grant

Principal investigators: Hoang, Trang K; Perreault, Claude; Thibault, Pierre

Keywords: Chemogenomic Vulnerability; Immunopeptidome; Primary T-All Samples; T-Cell Acute Lymphoblastic Leukemia (T-All); Tumor Specific Antigen

$856,800

Immunotherapeutic Targeting of the U1 snRNA Mutation in Cancer

Co-investigatorCIHR2020Project Grant

Principal investigators: Stein, Lincoln

Keywords: Cancer; Computational Biology; Immunotherapy; Non-Coding Rna; Proteomics; Targeted Cancer Therapy

$1,013,626

The proteogenomic landscape of tumour-specific antigens present in triplenegative breast cancers

Nominated PICIHR2018Operating Grant: CCS Innovation Grants

Principal investigators: Perreault, Claude

Keywords: Tumour-Specific Antigens

$67,000

Sexual dimorphism of thymic epithelial cells

Nominated PICIHR2017Catalyst Grant: Sex as a Variable in Biomedical Research

Principal investigators: Perreault, Claude

Keywords: Autoimmunity; Immune Senescence; Major Histocompatibility Complex; Mass Spectrometry; Sexual Dimorphism; Thymus; Transcriptome Sequencing

$150,000

Deep learning-based study of the endogenous retroviral-derived immunopeptidome in ovarian cancer.

SupervisorCIHR2017Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Trofimov, Assya

Keywords: Genomics, Proteomics, And Bioinformatics; Molecular Biology; Ovarian Cancer

$105,000

Immunobiology of thymic medullary stromal cells

Nominated PICIHR2016Project Grant

Principal investigators: Perreault, Claude

Keywords: Autoimmunity; Cell Sorting; Immune Tolerance; Major Histocompatibility Complex; Mass Spectrometry; Mouse Models; Promiscuous Gene Expression; Stem-Progenitor Cells; Thymus; Transcriptome Sequencing

$852,420

Thymus biology and the molecular definition of the immune self

Nominated PICIHR2015Foundation Grant

Principal investigators: Perreault, Claude

Keywords: Gene Expression; Major Histocompatibility Complex; Mass Spectrometry; Mouse Models; Proteasomes; Systems Biology; T-Cell Development; Thymus; Transcriptome Sequencing; Tumor Antigens

$1,401,966

Clinical application of a novel molecule that expands human cord blood stem cells

Co-investigatorCIHR2014Operating Grant

Principal investigators: Roy, Jean; Cohen, Sandra; Sauvageau, Guy

Keywords: Cord Blood Transplantation; Fed Batch Culture System; Hematopoietic Stem Cell Expansion; Novel Agonist Of Stem Cell Renewal; Phase I Clinical Study

$1,013,167

Functional genomics of thymic epithelial progenitor/stem cells

SupervisorCIHR2014Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Dumont-Lagacé, Maude

Keywords: Sex Hormones; System Biology; Thymic Epithelial Stem Cell; Thymic Involution; Thymic Regeneration; Transcriptomics

$105,000

Cinétique de renouvellement des cellules épithéliales thymiques in vivo

SupervisorCIHR2013Master's Award: Canada Graduate Scholarships

Principal investigators: Dumont-Lagacé, Maude

Keywords: Cellules Souches; Cytométrie De Flux; Différenciation Cellulaire; Immunobiologie; Immunofluorescence; Involution Thymique; Prolifération Cellulaire; Thymus; Transcriptomique; Vieillissement

$17,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Claude Perreault

Research

Latest papers

Latest funding

Noncanonical Transcription and Splicing Shape the Colorectal Cancer Immunopeptidome in MSI and MSS Tumors.

The cryptic immunopeptidome in health and disease.

CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling.

Tumor antigens preferentially derive from unmutated genomic sequences in melanoma and non-small cell lung cancer.

Immunogenicity of Non-Mutated Ovarian Cancer-Specific Antigens.

Autophagy degrades immunogenic endogenous retroelements induced by 5-azacytidine in acute myeloid leukemia.

Transposable elements regulate thymus development and function.

Breast cancer immunopeptidomes contain numerous shared tumor antigens.

Immunotargeting of a recurrent AML-specific neoantigen.

Introduction to the Special Issue: The Immunopeptidome.

Frequent collaborators

Pierre Thibault

Guy Sauvageau

Etienne Caron

Lambert Busque

Denis-Claude Roy

Moutih Rafei

Moutih Rafei

Jean Roy

Sandra Cohen

Francis Migneault

Nathalie Labrecque

Marc Therrien

Sylvie Lesage

Sylvain Meloche

Trang Hoang

Francis Rodier

Xavier Roucou

Xavier Roucou

Elliot Drobetsky

Julie Lessard

Mick Bhatia

Jiangping Wu

Elie Haddad

Sylvie Mader