Faculty profile

Louis-Charles Fortier

ResearcherMicrobiology and Infectious DiseasesUniversité de Sherbrooke

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Sherbrooke directory, so their courses may be missing. Find their university profile.

Louis-Charles Fortier

Researcher

Microbiology and Infectious Diseases

Health Sciences

Université de Sherbrooke

Sherbrooke, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
15 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 13 research grants (11 NSERC, 2 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Animal Models Bacteriophages Cell Surface Proteins Clostridioides Difficile Cryo-Em Genetic Engineering Genomics Phage Therapy

Latest papers

Isolation and Characterization of Clostridioides difficile Bacteriophages.
Methods in molecular biology (Clifton, N.J.) · 2026 · senior author
Structural determinants of SlpA-mediated phage recognition in Clostridioides difficile.
PLoS pathogens · 2025 · senior author
Deciphering the RNA-based regulation mechanism of the phage-encoded AbiF system in Clostridioides difficile.
PLoS genetics · 2025

All 49 publications

Latest funding

Demystifying virus-host interactions in Clostridioides difficile through genetic engineering of bacteriophages and the bacterial S-layer
CIHR · 2025 · Nominated PI
$1,071,000
Understanding the interplay between Shp-2 and microbiota in colonic inflammation
CIHR · 2023 · Co-investigator
$994,500
Replacement for Anaerobic Workstations
NSERC · 2023 · Principal investigator
$145,503

All 21 grants and awards

49 publications.

Isolation and Characterization of Clostridioides difficile Bacteriophages.

Royer ALM, Umansky AA, Fortier LC

Methods in molecular biology (Clifton, N.J.)2026Senior author

DOI: 10.1007/978-1-0716-5328-9_5 PMID: 42096149

Structural determinants of SlpA-mediated phage recognition in Clostridioides difficile.

Royer ALM, Dion É, Umansky AA, Avino M, Soutourina O, Fortier LC

PLoS pathogens2025Senior author

DOI: 10.1371/journal.ppat.1013724 PMID: 41296815

Deciphering the RNA-based regulation mechanism of the phage-encoded AbiF system in Clostridioides difficile.

Saunier M, Humbert A, Kreis V, Peltier J, Tisba A, Auxilien S, Blum M, Caldelari I, Lucier JF, Ueda J, Gautheret D, Toffano-Nioche C, Andreani J, Fortier LC, Soutourina O

PLoS genetics2025

DOI: 10.1371/journal.pgen.1011831 PMID: 40828859

Molecular mechanism of bacteriophage contraction structure of an S-layer-penetrating bacteriophage.

Wilson JS, Fortier LC, Fagan RP, Bullough PA

Life science alliance2025

DOI: 10.26508/lsa.202403088 PMID: 40139691

Protection against Clostridioides difficile disease by a naturally avirulent strain.

Dong Q, Harper S, McSpadden E, Son SS, Allen MM, Lin H, Smith RC, Metcalfe C, Burgo V, Woodson C, Sundararajan A, Rose A, McMillin M, Moran D, Little J, Mullowney MW, Sidebottom AM, Fortier LC, Shen A, Pamer EG

Cell host & microbe2025

DOI: 10.1016/j.chom.2024.11.003 PMID: 39610252

RNA-based regulation in bacteria-phage interactions.

Saunier M, Fortier LC, Soutourina O

Anaerobe2024

DOI: 10.1016/j.anaerobe.2024.102851 PMID: 38583547

Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain.

Dong Q, Harper S, McSpadden E, Son SS, Allen MM, Lin H, Smith RC, Metcalfe C, Burgo V, Woodson C, Sundararajan A, Rose A, McMillin M, Moran D, Little J, Mullowney M, Sidebottom AM, Shen A, Fortier LC, Pamer EG

bioRxiv : the preprint server for biology2024

DOI: 10.1101/2024.05.06.592814 PMID: 38766138

Chronic Diarrhea Caused by a Klebsiella oxytoca Toxin Producer Strain Following Antibiotic-Associated Hemorrhagic Colitis: Successful Treatment by Fecal Microbiota Transplant.

Granger MF, Kelly M, Fortier LC, Fournier E, Côté-Gravel J, Malouin F, Valiquette L, Lévesque S

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America2023

DOI: 10.1093/cid/ciad436 PMID: 37477511

Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile.

Dong Q, Lin H, Allen MM, Garneau JR, Sia JK, Smith RC, Haro F, McMillen T, Pope RL, Metcalfe C, Burgo V, Woodson C, Dylla N, Kohout C, Sundararajan A, Snitkin ES, Young VB, Fortier LC, Kamboj M, Pamer EG

Cell reports2023

DOI: 10.1016/j.celrep.2023.112861 PMID: 37523264

Assessment of antibacterial properties and skin irritation potential of anodized aluminum impregnated with various quaternary ammonium.

Jann J, Gascon S, Drevelle O, Fradette J, Auclair-Gilbert M, Soucy G, Fortier LC, Faucheux N

Biomaterials advances2023

DOI: 10.1016/j.bioadv.2023.213433 PMID: 37104962

Demystifying virus-host interactions in Clostridioides difficile through genetic engineering of bacteriophages and the bacterial S-layer

Nominated PICIHR2025Project Grant

Principal investigators: Fortier, Louis-Charles

Keywords: Animal Models; Bacteriophages; Cell Surface Proteins; Clostridioides Difficile; Cryo-Em; Genetic Engineering; Genomics; Phage Therapy; Prophages; S-Layer

$1,071,000

Understanding the interplay between Shp-2 and microbiota in colonic inflammation

Co-investigatorCIHR2023Project Grant

Principal investigators: Rivard, Nathalie

Keywords: Colitis; Gut Microbiota; Inflammatory Bowel Diseases; Intestinal Epithelium; Intracellular Signaling; Phosphatases; Toll-Like Receptors

$994,500

Replacement for Anaerobic Workstations

Principal investigatorNSERC2023Research Tools and Instruments

Principal investigators: Fortier, Louis-Charles

$145,503

Demystifying virus-host interactions in Clostridioides difficile through genetic engineering of bacteriophages and the bacterial S-layer

Nominated PICIHR2023Project Grant - PA: Antimicrobial Resistance (Bridge Grant)

Principal investigators: Fortier, Louis-Charles

Keywords: Animal Models; Bacteriophages; Cell Surface Proteins; Clostridioides Difficile; Cryo-Em; Genetic Engineering; Genomics; Phage Therapy; Prophages; S-Layer

$100,000

Évaluation de l'efficacité des probiotiques sur les affections post-COVID-19.

Co-investigatorCIHR2021Op Grant: Emerging COVID-19 Research Gaps & Priorities - Post COVID-19 condition

Principal investigators: Pasquier, Jean Charles; Beaulieu, Jean-François; Chaillet, Nils; Laforest-Lapointe, Isabelle; Piche, Alain; Robitaille, Julie

Keywords: Affections Post-Covid; Application Des Connaissances; Essai Randomisé Contrôlé; Microbiote; Nutrition; Probiotiques; Sars-Cov-2; Virus

$997,273

Développement d'une surface d'aluminium anodisé pour des applications virucides, bactéricides et sporicides

Co-investigatorNSERC2021Alliance Grants

Principal investigators: Soucy, Gervais

$406,000

L'Aluminium anodisé A3S : une surface virucide pour lutter contre la pandémie de COVID-19 dans les hôpitaux, les CHSLD, et les lieux publics_x000d_

Principal investigatorNSERC2020Alliance Grants

Principal investigators: Fortier, Louis-Charles

$50,000

Phage-host interactions in pathogenic and commensal clostridia

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Fortier, Louis-Charles

$180,000

Replacement for Microbial Growth Assay Cluster

Co-investigatorNSERC2019Research Tools and Instruments

Principal investigators: AbouElela, Sherif

$143,350

Initial vancomycin taper for the prevention of recurrent Clostridium difficile infection

Co-investigatorCIHR2018Project Grant

Principal investigators: Lee, Todd C; McDonald, Emily G

Keywords: Clostridium Dificile; Prevention; Recurrence; Vancomycin

$378,676

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Louis-Charles Fortier

Research

Latest papers

Latest funding

Isolation and Characterization of Clostridioides difficile Bacteriophages.

Structural determinants of SlpA-mediated phage recognition in Clostridioides difficile.

Deciphering the RNA-based regulation mechanism of the phage-encoded AbiF system in Clostridioides difficile.

Molecular mechanism of bacteriophage contraction structure of an S-layer-penetrating bacteriophage.

Protection against Clostridioides difficile disease by a naturally avirulent strain.

RNA-based regulation in bacteria-phage interactions.

Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain.

Chronic Diarrhea Caused by a Klebsiella oxytoca Toxin Producer Strain Following Antibiotic-Associated Hemorrhagic Colitis: Successful Treatment by Fecal Microbiota Transplant.

Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile.

Assessment of antibacterial properties and skin irritation potential of anodized aluminum impregnated with various quaternary ammonium.

Demystifying virus-host interactions in Clostridioides difficile through genetic engineering of bacteriophages and the bacterial S-layer

Understanding the interplay between Shp-2 and microbiota in colonic inflammation

Replacement for Anaerobic Workstations

Demystifying virus-host interactions in Clostridioides difficile through genetic engineering of bacteriophages and the bacterial S-layer

Évaluation de l'efficacité des probiotiques sur les affections post-COVID-19.

Développement d'une surface d'aluminium anodisé pour des applications virucides, bactéricides et sporicides

L'Aluminium anodisé A3S : une surface virucide pour lutter contre la pandémie de COVID-19 dans les hôpitaux, les CHSLD, et les lieux publics_x000d_

Phage-host interactions in pathogenic and commensal clostridia

Replacement for Microbial Growth Assay Cluster

Initial vancomycin taper for the prevention of recurrent Clostridium difficile infection

Frequent collaborators

Alfredo Menendez

Subburaj Ilangumaran

Allison McGeer

Sheela Ramanathan

Vincent Burrus

Nathalie Perreault

Julie Fradette

Daniel Lafontaine

Nathalie Rivard