Faculty profile

Nathalie Perreault

ResearcherAnatomie et biologie cellulaireUniversité de Sherbrooke

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Sherbrooke directory, so their courses may be missing. Find their university profile.

Nathalie Perreault

Researcher

Anatomie et biologie cellulaire

Health Sciences

Université de Sherbrooke

Sherbrooke, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
6 publications in the last five years, latest in 2026.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 6 research grants (4 CIHR, 2 NSERC), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Gastrointestinal Ecm Biodynamics Gastrointestinal Microenvironment Gut Organoids Matrix Stiffness Mechanotransduction Epithelial Mesenchymal Communication Extracellular Vesicles Gut-Related Diseases (Ibd, Cac)

Latest papers

HNF4A intestinal ablation positively influences the fate of ileal goblet cells during Salmonella typhimurium infection.
American journal of physiology. Gastrointestinal and liver physiology · 2026
Defects in the expression of colonic host defense factors associate with barrier dysfunction induced by a high-fat/high-cholesterol diet.
Anatomical record (Hoboken, N.J. : 2007) · 2023
FOXL1+ Telocytes in mouse colon orchestrate extracellular matrix biodynamics and wound repair resolution.
Journal of proteomics · 2023 · senior author

All 31 publications

Latest funding

Targeting mesenchymal cells communication pathways on epithelial cells behaviour in gut-related diseases
CIHR · 2024 · Nominated PI
$1,143,675
Biomolecular and biomechanical impact of Foxl1+ mesenchymal telocytes on epithelial cell behaviour in gut-related diseases.
CIHR · 2019 · Nominated PI
$1,105,426
Mechanisms regulating autophagy in intestinal epithelial secretory cells
NSERC · 2018 · Principal investigator
$192,000

All 8 grants and awards

31 publications.

HNF4A intestinal ablation positively influences the fate of ileal goblet cells during Salmonella typhimurium infection.

Gómez DP, Nicolás VR, Marrero GC, De Castro AC, Jones C, Leon Chirino LM, Perreault N, Menendez A, Boudreau F

American journal of physiology. Gastrointestinal and liver physiology2026

DOI: 10.1152/ajpgi.00224.2025 PMID: 41452599

Defects in the expression of colonic host defense factors associate with barrier dysfunction induced by a high-fat/high-cholesterol diet.

Valdes J, Gagné-Sansfaçon J, Reyes V, Armas A, Marrero G, Moyo-Muamba M, Ramanathan S, Perreault N, Ilangumaran S, Rivard N, Fortier LC, Menendez A

Anatomical record (Hoboken, N.J. : 2007)2023

DOI: 10.1002/ar.25083 PMID: 36196983

FOXL1+ Telocytes in mouse colon orchestrate extracellular matrix biodynamics and wound repair resolution.

Pomerleau V, Nicolas VR, Jurkovic CM, Faucheux N, Lauzon MA, Boisvert FM, Perreault N

Journal of proteomics2023Senior author

DOI: 10.1016/j.jprot.2022.104755 PMID: 36272709

Comprehensive Profiling of Early Neoplastic Gastric Microenvironment Modifications and Biodynamics in Impaired BMP-Signaling FoxL1+-Telocytes.

Alfonso AB, Pomerleau V, Nicolás VR, Raisch J, Jurkovic CM, Boisvert FM, Perreault N

Biomedicines2022Senior author

DOI: 10.3390/biomedicines11010019 PMID: 36672527

Fibrin(ogen) Is Constitutively Expressed by Differentiated Intestinal Epithelial Cells and Mediates Wound Healing.

Seltana A, Cloutier G, Reyes Nicolas V, Khalfaoui T, Teller IC, Perreault N, Beaulieu JF

Frontiers in immunology2022

DOI: 10.3389/fimmu.2022.916187 PMID: 35812445

The transcription factor hepatocyte nuclear factor 4A acts in the intestine to promote white adipose tissue energy storage.

Girard R, Tremblay S, Noll C, St-Jean S, Jones C, Gélinas Y, Maloum-Rami F, Perreault N, Laplante M, Carpentier AC, Boudreau F

Nature communications2022

DOI: 10.1038/s41467-021-27934-w PMID: 35017517

Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling.

Reyes Nicolás V, Allaire JM, Alfonso AB, Pupo Gómez D, Pomerleau V, Giroux V, Boudreau F, Perreault N

Cells2021Senior author

DOI: 10.3390/cells10112954 PMID: 34831177

NCOR1 Sustains Colorectal Cancer Cell Growth and Protects against Cellular Senescence.

St-Jean S, De Castro AC, Lecours M, Jones C, Rivard N, Rodier F, Perreault N, Boudreau F

Cancers2021

DOI: 10.3390/cancers13174414 PMID: 34503224

HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide.

Girard R, Darsigny M, Jones C, Maloum-Rami F, Gélinas Y, Carpentier AC, Laplante M, Perreault N, Boudreau F

Scientific reports2019

DOI: 10.1038/s41598-019-41061-z PMID: 30862908

Loss of PTEN Signaling in Foxl1+ Mesenchymal Telocytes Initiates Spontaneous Colonic Neoplasia in Mice.

Langlois MJ, Servant R, Reyes Nicolás V, Jones C, Roy SAB, Paquet M, Carrier JC, Rivard N, Boudreau F, Perreault N

Cellular and molecular gastroenterology and hepatology2019Senior author

DOI: 10.1016/j.jcmgh.2019.05.007 PMID: 31146066

Targeting mesenchymal cells communication pathways on epithelial cells behaviour in gut-related diseases

Nominated PICIHR2024Project Grant

Principal investigators: Perreault, Nathalie

Keywords: Epithelial Mesenchymal Communication; Extracellular Vesicles; Gastrointestinal Ecm Biodynamics; Gastrointestinal Microenvironment; Gut Organoids; Gut-Related Diseases (Ibd, Cac); Matrix Stiffness; Mechanotransduction; Mimetic Matrices; Subepithelial Mesenchymal Cells

$1,143,675

Biomolecular and biomechanical impact of Foxl1+ mesenchymal telocytes on epithelial cell behaviour in gut-related diseases.

Nominated PICIHR2019Project Grant

Principal investigators: Perreault, Nathalie

Keywords: Gastrointestinal Ecm Biodynamics; Gastrointestinal Foxl1+ Telocytes; Gastrointestinal Mesenchymal Stem Cell Niche; Gastrointestinal Microenvironment; Gastrointestinal Mucosa; Genetically Modified Mice Models; Gut Organoids; Gut-Related Diseases; Matrix Stiffness; Mechanotransduction

$1,105,426

Mechanisms regulating autophagy in intestinal epithelial secretory cells

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Perreault, Nathalie

$192,000

The Nuclear Receptor HNF4A as a Regulator of WNT Ligands: Biological Impact of this Novel Interaction in Gut Diseases

Co-investigatorCIHR2017Project Grant

Principal investigators: Boudreau, François

Keywords: Colorectal Cancer; Conditional Knockouts; Intestinal Bowel Diseases; Intestinal Epithelium; Intestinal Mesenchyme; Intestinal Organoids; Intestinal Stem Cells; Proteomics; Transcription Factor; Transcriptomics

$1,082,475

Functional contribution of the Bone Morphogenetic Proteins signaling pathway in the reprogramming of gastrointestinal reactive mesenchyme

Nominated PICIHR2014Operating Grant

Principal investigators: Perreault, Nathalie

Keywords: Bmp Signaling Pathway; Conditional Knockout/Cre-Loxp System; Epigenetic; Functional Genomics; Gastro-Intestinal Epithelial-Mesenchymal Crosstalk; Gatro-Intestinal Cancer; Molecular Genetics; Reactive Mesenchyme; Smad Transcription Factors/Gene Regulation; Stromagenesis

$768,180

Role of the nuclear receptor corepressor-1 in blocking inflammatory gene expression

Co-investigatorCIHR2013Operating Grant

Principal investigators: Boudreau, François

Keywords: Cell Culture; Gene Expression Assays; Gene Silencing; Gene Transcription; Inflammatory Bowel Diseases; Mouse Conditional Knockout

$661,649

Distinctive contribution of epithelial and mesenchymal Bmp signaling in intestinal homeostasis.

Nominated PICIHR2010Operating Grant

Principal investigators: Perreault, Nathalie

Keywords: Bmp Signaling Pathway; Cell Culture; Conditional Knockout/Cre-Loxp System; Experimental Colitis; Gastro-Intestinal Epithelial-Mesenchymal Crosstalk; Gastro-Intestinal Proliferation And Differentiation; Gatro-Intestinal Cancer; Ibd; Molecular Genetics; Smad Transcription Factors

$577,408

Rôle de l'ilk (integrin linked kinase) dans la régulation de la proliferation et la differenciation cellulaire dans le système digestif

Principal investigatorNSERC2003Discovery Grants Program - Individual

Principal investigators: Perreault, Nathalie

$150,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Nathalie Perreault

Research

Latest papers

Latest funding

HNF4A intestinal ablation positively influences the fate of ileal goblet cells during Salmonella typhimurium infection.

Defects in the expression of colonic host defense factors associate with barrier dysfunction induced by a high-fat/high-cholesterol diet.

FOXL1+ Telocytes in mouse colon orchestrate extracellular matrix biodynamics and wound repair resolution.

Comprehensive Profiling of Early Neoplastic Gastric Microenvironment Modifications and Biodynamics in Impaired BMP-Signaling FoxL1+-Telocytes.

Fibrin(ogen) Is Constitutively Expressed by Differentiated Intestinal Epithelial Cells and Mediates Wound Healing.

The transcription factor hepatocyte nuclear factor 4A acts in the intestine to promote white adipose tissue energy storage.

Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling.

NCOR1 Sustains Colorectal Cancer Cell Growth and Protects against Cellular Senescence.

HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide.

Loss of PTEN Signaling in Foxl1+ Mesenchymal Telocytes Initiates Spontaneous Colonic Neoplasia in Mice.

Targeting mesenchymal cells communication pathways on epithelial cells behaviour in gut-related diseases

Biomolecular and biomechanical impact of Foxl1+ mesenchymal telocytes on epithelial cell behaviour in gut-related diseases.

Mechanisms regulating autophagy in intestinal epithelial secretory cells

The Nuclear Receptor HNF4A as a Regulator of WNT Ligands: Biological Impact of this Novel Interaction in Gut Diseases

Functional contribution of the Bone Morphogenetic Proteins signaling pathway in the reprogramming of gastrointestinal reactive mesenchyme

Role of the nuclear receptor corepressor-1 in blocking inflammatory gene expression

Distinctive contribution of epithelial and mesenchymal Bmp signaling in intestinal homeostasis.

Rôle de l'ilk (integrin linked kinase) dans la régulation de la proliferation et la differenciation cellulaire dans le système digestif

Frequent collaborators

Nathalie Rivard

François Boudreau

Alfredo Menendez

Mathieu Laplante

Fernand-Pierre Gendron

Elena Verdu

Subburaj Ilangumaran

Caroline Saucier

Francis Rodier

Louis-Charles Fortier

Sheela Ramanathan

Premysl Bercik

Giada De Palma

Philippe Sarret

Nathalie Perreault

Research

Latest papers

Latest funding

HNF4A intestinal ablation positively influences the fate of ileal goblet cells during Salmonella typhimurium infection.

Defects in the expression of colonic host defense factors associate with barrier dysfunction induced by a high-fat/high-cholesterol diet.

FOXL1+ Telocytes in mouse colon orchestrate extracellular matrix biodynamics and wound repair resolution.

Comprehensive Profiling of Early Neoplastic Gastric Microenvironment Modifications and Biodynamics in Impaired BMP-Signaling FoxL1+-Telocytes.

Fibrin(ogen) Is Constitutively Expressed by Differentiated Intestinal Epithelial Cells and Mediates Wound Healing.

The transcription factor hepatocyte nuclear factor 4A acts in the intestine to promote white adipose tissue energy storage.

Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling.

NCOR1 Sustains Colorectal Cancer Cell Growth and Protects against Cellular Senescence.

HNF4&#x3b1; is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide.

Loss of PTEN Signaling&#xa0;in&#xa0;Foxl1+ Mesenchymal Telocytes Initiates Spontaneous Colonic Neoplasia in Mice.

Targeting mesenchymal cells communication pathways on epithelial cells behaviour in gut-related diseases

Biomolecular and biomechanical impact of Foxl1+ mesenchymal telocytes on epithelial cell behaviour in gut-related diseases.

Mechanisms regulating autophagy in intestinal epithelial secretory cells

The Nuclear Receptor HNF4A as a Regulator of WNT Ligands: Biological Impact of this Novel Interaction in Gut Diseases

Functional contribution of the Bone Morphogenetic Proteins signaling pathway in the reprogramming of gastrointestinal reactive mesenchyme

Role of the nuclear receptor corepressor-1 in blocking inflammatory gene expression

Distinctive contribution of epithelial and mesenchymal Bmp signaling in intestinal homeostasis.

Rôle de l'ilk (integrin linked kinase) dans la régulation de la proliferation et la differenciation cellulaire dans le système digestif

Frequent collaborators

Nathalie Rivard

François Boudreau

Alfredo Menendez

Mathieu Laplante

Fernand-Pierre Gendron

Elena Verdu

Subburaj Ilangumaran

Caroline Saucier

Francis Rodier

Louis-Charles Fortier

Sheela Ramanathan

Premysl Bercik

Giada De Palma

Philippe Sarret

HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide.

Loss of PTEN Signaling in Foxl1+ Mesenchymal Telocytes Initiates Spontaneous Colonic Neoplasia in Mice.