Levinus Dieleman, University of Alberta

Research

Bacteria Cytokines Prebiotics Ulcerative Colitis

Latest papers

The Impact of Proactive Fecal Calprotectin Collection in an Outreach Protocol for Biologic-Naïve Ulcerative Colitis Patients-Ulcerative Colitis Clinical Outreach (UCCO).
Diseases (Basel, Switzerland) · 2025
Early Life Exposure to Parental Crohn’s Disease Is Associated With Offspring’s Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn’s Disease
Gastroenterology · 2025
Stricture dilation via balloon-assisted endoscopy in Crohn's disease: approach and intraprocedural outcomes with the single-balloon and double-balloon systems.
Therapeutic advances in gastroenterology · 2024

All 9 publications

Latest funding

IMAGINE (Inflammation, Microbiome, and Alimentation: Gastro-Intestinal and Neuropsychiatric Effects) SPOR Chronic Disease Network - Knowledge Mobilization & Implementation Science Phase 2
CIHR · 2021 · Principal investigator
$3,745,000
Assessing gluten allergenicity in ancient and modern wheat to develop strategies to reduce celiac disease causing epitopes in wheat gluten proteins
NSERC · 2017 · Co-investigator
$170,800
Relapse prevention of ulcerative colitis by prebiotics: efficacy and protective mechanisms.
CIHR · 2013 · Nominated PI
$446,720

All 4 grants and awards

9 publications.

01

The Impact of Proactive Fecal Calprotectin Collection in an Outreach Protocol for Biologic-Naïve Ulcerative Colitis Patients-Ulcerative Colitis Clinical Outreach (UCCO).

MacKay S, Parsons D, Hagerman C, Lytvyak E, Dieleman L, Hoentjen F, Kroeker K, Peerani F, Wong K, Gozdzik M, Oguro K, McMullen T, Halloran B

Diseases (Basel, Switzerland)2025

DOI: 10.3390/diseases14010002 PMID: 41590218

02

Early Life Exposure to Parental Crohn’s Disease Is Associated With Offspring’s Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn’s Disease

Lee S-H, Bushra M, Qiu L, Griffiths AM, Turpin W, Croitoru K, Lee S-H, Bushra M, Qiu L, Shao J

Gastroenterology202518 citations

DOI: 10.1053/j.gastro.2024.09.033

03

Stricture dilation via balloon-assisted endoscopy in Crohn's disease: approach and intraprocedural outcomes with the single-balloon and double-balloon systems.

Halloran BP, Reeson M, Teshima C, Kroeker K, Huang V, Dieleman L, Holmes P, Baumgart DC, Wong K, Hoentjen F, Peerani F, Zepeda-Gomez S

Therapeutic advances in gastroenterology2024

DOI: 10.1177/17562848241230904 PMID: 38425369

04

Fecal Calprotectin May Predict Adverse Pregnancy-Related Outcomes in Patients with Inflammatory Bowel Disease.

Tandon P, Lee EY, Maxwell C, Hitz L, Ambrosio L, Dieleman L, Halloran B, Kroeker K, Huang VM

Digestive diseases and sciences2021

DOI: 10.1007/s10620-020-06381-5 PMID: 32533542

05

Innovative Online Educational Portal Improves Disease-Specific Reproductive Knowledge Among Patients With Inflammatory Bowel Disease.

Wierstra K, Sutton R, Bal J, Ismond K, Dieleman L, Halloran B, Kroeker K, Fedorak R, Berga KA, Huang V

Inflammatory bowel diseases2018

DOI: 10.1093/ibd/izy161 PMID: 29850827

06

Ulcerative Colitis Patients With Clostridium difficile are at Increased Risk of Death, Colectomy, and Postoperative Complications: A Population-Based Inception Cohort Study.

Negrón ME, Rezaie A, Barkema HW, Rioux K, De Buck J, Checkley S, Beck PL, Carroll M, Fedorak RN, Dieleman L, Panaccione R, Ghosh S, Kaplan GG

The American journal of gastroenterology2016

DOI: 10.1038/ajg.2016.106 PMID: 27091322

07

The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats.

Lin XB, Farhangfar A, Valcheva R, Sawyer MB, Dieleman L, Schieber A, Gänzle MG, Baracos V

PloS one2014

DOI: 10.1371/journal.pone.0083644 PMID: 24454707

08

Crohn's disease and the footprints of flagellin: etiopathogenic clue or epiphenomenon?

Rioux K, Dieleman L

Inflammatory bowel diseases2005Senior author

DOI: 10.1097/01.mib.0000183425.64457.c4 PMID: 16189425

09

Mucosal adherence of Escherichia coli in inflammatory bowel disease: learning more about our closest "friends".

Rioux K, Dieleman L

Inflammatory bowel diseases2005Senior author

DOI: 10.1097/00054725-200501000-00013 PMID: 15674119

IMAGINE (Inflammation, Microbiome, and Alimentation: Gastro-Intestinal and Neuropsychiatric Effects) SPOR Chronic Disease Network - Knowledge Mobilization & Implementation Science Phase 2

Principal investigatorCIHR2021SPOR Networks - Knowledge Mobilization and Implementation Science

Principal investigators: Moayyedi, Paul; Calliou, Skylin N; Daley, Kimberlee; De Nino, Alysia; Desjarlais, Rhonda; Marsiglio, Megan L; Munro, Sandra; Baumgart, Daniel C; Bercik, Premysl; Bernstein, Charles N; de Souza, Russell J; Dieleman, Levinus A; D'Silva, Adrijana; Ghia, Jean-Eric; Graff, Lesley A; Jones, Meaghan J; Kao, Dina H; Lavis, John N; Leontiadis, Grigorios; Libertucci, Josie; Ma, Christopher; Madsen, Karen L; Marshall, Deborah A; Narula, Neeraj; Nguyen, Geoffrey C; Otley, Anthony R; Panaccione, Remo; Pena-Sanchez, Juan-Nicolas; Presseau, Justin; Ruzycki, Shannon M; Surette, Michael G; Swain, Mark G; Tandon, Puneeta; Taylor, Valerie Hannah; Tremblay, Melissa; Tripp, Dean A; Vanner, Stephen J; Verdu, Elena F; Walters, Thomas D; Wine, Eytan

Keywords: Anxiety; Depression; Diet; Implementation Science; Inflammatory Bowel Disease; Irritable Bowel Syndrome; Knowledge Mobilization; Microbiome; Patient Orientated Research

$3,745,000

Assessing gluten allergenicity in ancient and modern wheat to develop strategies to reduce celiac disease causing epitopes in wheat gluten proteins

Co-investigatorNSERC2017Collaborative Research and Development Grants

Principal investigators: Chibbar, Ravindra

$170,800

Relapse prevention of ulcerative colitis by prebiotics: efficacy and protective mechanisms.

Nominated PICIHR2013Operating Grant

Principal investigators: Dieleman, Levinus A

Keywords: Bacteria; Cytokines; Prebiotics; Ulcerative Colitis

$446,720

The role of the Intestinal Microbiome in Post-Operative Recurrence of Crohn's Ileocolitis

Co-investigatorCIHR2009Canadian Microbiome Initiative - LOI

Principal investigators: Madsen, Karen L; Fedorak, Richard N; Vogel, Hans (Harm) J

Keywords: Inflammatory Bowel Disease; Metabolomics; Metagenomics

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Pediatrics
Biostatistics Division
Physiology and Pharmacology
Biochemistry, Microbiology & Immunology
Immunology
Department of Medicine
Other

1 shared papers, latest 2025

Bruce Vallance

Pediatrics

1 shared papers, latest 2025

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2021

Subject: Prospective PhD student: Bacteria Dear Professor Dieleman, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "The Impact of Proactive Fecal Calprotectin Collection in an Outreach Protocol for Biologic-Naïve Ulcerative Colitis Patients-Ulcerative Colitis Clinical Outreach (UCCO)." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "IMAGINE (Inflammation, Microbiome, and Alimentation: Gastro-Intestinal and Neuropsychiatric Effects) SPOR Chronic Disease Network - Knowledge Mobilization & Implementation Science Phase 2" (2021), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Levinus Dieleman

Research

Latest papers

Latest funding

The Impact of Proactive Fecal Calprotectin Collection in an Outreach Protocol for Biologic-Na&#xef;ve Ulcerative Colitis Patients-Ulcerative Colitis Clinical Outreach (UCCO).

Early Life Exposure to Parental Crohn’s Disease Is Associated With Offspring’s Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn’s Disease

Stricture dilation via balloon-assisted endoscopy in Crohn's disease: approach and intraprocedural outcomes with the single-balloon and double-balloon systems.

Fecal Calprotectin May Predict Adverse Pregnancy-Related Outcomes in Patients with Inflammatory Bowel Disease.

Innovative Online Educational Portal Improves Disease-Specific Reproductive Knowledge Among Patients With Inflammatory Bowel Disease.

Ulcerative Colitis Patients With Clostridium difficile are at Increased Risk of Death, Colectomy, and Postoperative Complications: A Population-Based Inception Cohort Study.

The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats.

Crohn's disease and the footprints of flagellin: etiopathogenic clue or epiphenomenon?

Mucosal adherence of Escherichia coli in inflammatory bowel disease: learning more about our closest "friends".

IMAGINE (Inflammation, Microbiome, and Alimentation: Gastro-Intestinal and Neuropsychiatric Effects) SPOR Chronic Disease Network - Knowledge Mobilization & Implementation Science Phase 2

Assessing gluten allergenicity in ancient and modern wheat to develop strategies to reduce celiac disease causing epitopes in wheat gluten proteins

Relapse prevention of ulcerative colitis by prebiotics: efficacy and protective mechanisms.

The role of the Intestinal Microbiome in Post-Operative Recurrence of Crohn's Ileocolitis

Frequent collaborators

Karen Kroeker

Farhad Peerani

Remo Panaccione

Anthony Otley

David Mack

Alain Bitton

Wei Xu

Richard Fedorak

Gilaad Kaplan

Vickie Baracos

Sanjay Murthy

Gilaad Kaplan

Osvaldo Espin Garcia

Karen Madsen

Kenneth Croitoru

Paul Moayyedi

Michael Surette

John Kenneth Marshall

Paul Beck

Thomas Walters

Todd McMullen

Bruce Vallance

The Impact of Proactive Fecal Calprotectin Collection in an Outreach Protocol for Biologic-Naïve Ulcerative Colitis Patients-Ulcerative Colitis Clinical Outreach (UCCO).