This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.
Research
Latest papers
MMP-2 inhibition attenuates ER stress-mediated cell death during myocardial ischemia-reperfusion injury by preserving IRE1α.
Journal of molecular and cellular cardiology · 2025 · senior author
Matrix metalloproteinase inhibition protects against junctophilin-2 proteolysis during doxorubicin-induced cardiotoxicity.
British journal of pharmacology · 2025 · senior author
Sarcoplasmic reticulum calcium ATPase (SERCA) proteolysis by matrix metalloproteinase-2 contributes to vascular dysfunction in early hypertension.
European journal of pharmacology · 2024
Latest funding
- $1,794,502
Matrix metalloproteinases in cardiovascular health and disease: from bench to bedside
CIHR · 2014 · Nominated PI
- $200,000
Role of matrix metalloproteinase (MMP)-2 in regulating smooth muscle contraction
NSERC · 2011 · Principal investigator
- $655,391
Novel regulation and targets of matrix metalloproteinase-2 in the ischemic heart
CIHR · 2010 · Nominated PI
80 publications.
MMP-2 inhibition attenuates ER stress-mediated cell death during myocardial ischemia-reperfusion injury by preserving IRE1α.
Bassiouni W, Mahmud Z, Simmen T, Seubert JM, Schulz R
Matrix metalloproteinase inhibition protects against junctophilin-2 proteolysis during doxorubicin-induced cardiotoxicity.
Bassiouni W, Chan BYH, Roczkowsky A, Kranrod JW, Mahmud Z, Primeau JO, Cho WJ, Young HS, Seubert JM, Schulz R
Sarcoplasmic reticulum calcium ATPase (SERCA) proteolysis by matrix metalloproteinase-2 contributes to vascular dysfunction in early hypertension.
Blascke de Mello MM, Neves VGO, Parente JM, Pernomian L, de Oliveira IS, Pedersoli CA, Awata WMC, Tirapelli CR, Arantes EC, Tostes RCA, Schulz R, Castro MM
N-Terminomic Identification of Intracellular MMP-2 Substrates in Cardiac Tissue.
Hartley B, Bassiouni W, Roczkowsky A, Fahlman R, Schulz R, Julien O
The role of zinc and matrix metalloproteinases in myofibrillar protein degradation in critical illness myopathy.
Ribeiro F, Zhang X, Wen Y, Cacciani N, Hedström Y, Xia Z, Schulz R, Larsson L
Data-Independent Acquisition Proteomics and N-Terminomics Methods Reveal Alterations in Mitochondrial Function and Metabolism in Ischemic-Reperfused Hearts.
Hartley B, Bassiouni W, Roczkowsky A, Fahlman R, Schulz R, Julien O
Matrix metalloproteinase-2 proteolyzes mitofusin-2 and impairs mitochondrial function during myocardial ischemia-reperfusion injury.
Bassiouni W, Valencia R, Mahmud Z, Seubert JM, Schulz R
An interferon gamma response signature links myocardial aging and immunosenescence.
Ashour D, Rebs S, Arampatzi P, Saliba AE, Dudek J, Schulz R, Hofmann U, Frantz S, Cochain C, Streckfuß-Bömeke K, Campos Ramos G
The roles of intracellular proteolysis in cardiac ischemia-reperfusion injury.
Hartley B, Bassiouni W, Schulz R, Julien O
Staurosporine-induced cleavage of apoptosis-inducing factor in human fibrosarcoma cells is independent of matrix metalloproteinase-2.
Bassiouni W, Seubert JM, Schulz R
Matrix metalloproteinases in cardiovascular health and disease: from bench to bedside
Principal investigators: Schulz, Richard (Rick)
Keywords: Cardiac; Clinical Trials; Enzyme Inhibitor Pharmacology; Ischemic/Inflammatory Heart Disease; Matrix Metalloproteinases; Mitochondria; Mitochondria-Associated Membrane; Nuclei; Protease Substrates; Protein Structure; Reactive Oxygen-Nitrogen Species; Skeletal And Smooth Muscles
Role of matrix metalloproteinase (MMP)-2 in regulating smooth muscle contraction
Principal investigators: Schulz, Richard
Novel regulation and targets of matrix metalloproteinase-2 in the ischemic heart
Principal investigators: Schulz, Richard (Rick)
Keywords: Cardiac Myocytes; Drug-Protein Interaction; Enzyme Assays; Ischemia-Reperfusion; Isolated Heart; Matrix Metalloproteinase; Protein Structure; Reactive Oxygen/Nitrogen Species
Matrix metalloproteinase-2 (MMP-2) in myocardial cell death from oxidative stress injury
Principal investigators: Schulz, Richard (Rick)
Keywords: Apoptosis; Cell Death; Matrix Metalloproteinases; Necrosis; Oxidative Stress; Proteases
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Pathology & Molecular Medicine
- Pediatrics/Pharmacology
- Pediatrics
- Physiology
- Cell Biology
- Chemistry
- Medicine
- Other
Co-authors at University of Alberta, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Mahmoud Ali
Pathology & Molecular Medicine
9 shared papers, latest 2016
Zamaneh Kassiri
Physiology
3 shared papers, latest 2014
Po-Yin Cheung
Pediatrics
3 shared papers, latest 2015
Richard Fahlman
Faculty
2 shared papers, latest 2024
Thomas Simmen
Cell Biology
2 shared papers, latest 2025
Peter Hwang
Medicine
1 shared papers, latest 2021
Harald Becher
Faculty
1 shared papers, latest 2014
Mariane Bertagnolli
Faculty
1 shared papers, latest 2014
Liang Li
Chemistry
1 shared papers, latest 2019
Mariane Bertagnolli
Faculty
1 shared papers, latest 2014
Peter Kavsak
Pathology & Molecular Medicine
1 shared papers, latest 2021
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