This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Building Resilience in Academic Science and Medicine.
Arteriosclerosis, thrombosis, and vascular biology · 2026
Necroptosis is a key contributor to impaired cardiac repair following myocardial infarction.
Cell death & disease · 2026 · senior author
Rethinking cell death in pressure-overload heart failure: a sex-specific necroptosis paradigm.
American journal of physiology. Heart and circulatory physiology · 2026 · senior author
Latest funding
- $699,975
Modulation of endothelial cells to reduce plaque formation, independent from plasma cholesterol levels
CIHR · 2024 · Nominated PI
- $250,000
Enriched hydrogel scaffold as a platform for cell and drug delivery to repair aortic aneurysm
SSHRC · 2023 · Principal investigator
- $117,000
Deciphering the role of ADAM15 vs. ADAM17 in fibroblast function: Mechanobiology vs. Proteolysis
NSERC · 2022 · Principal investigator
121 publications.
Building Resilience in Academic Science and Medicine.
Nguyen PK, Rodriguez-Miguelez P, Alfaidi M, Erbay E, Freed JK, Hansen L, Kassiri Z, Lu HS, Oliveira SD, Wu AW, Zhang H, Chen ZB, ATVB Women’s Leadership Committee
Necroptosis is a key contributor to impaired cardiac repair following myocardial infarction.
Al Rimon R, Li Y, Meganathan I, Wang F, Murray AG, Oudit GY, Epelman S, Clemente-Casares X, Kassiri Z
Rethinking cell death in pressure-overload heart failure: a sex-specific necroptosis paradigm.
Al Rimon R, Krishnan V, Kassiri Z
Temporal inhibition of ADAM17 in fibroblasts reduces stiffness and promotes vascularization following myocardial infarction.
Li Y, Al Rimon R, Wang F, Li H, Epelman S, Tallquist MD, Westover L, Oudit GY, Kassiri Z
Loss of ADAM17 in smooth muscle cells enhances their transformation to macrophage-like cells leading to more severe atherosclerosis in mice.
Meganathan I, Kilic T, Al Rimon R, Naiya T, Krishnan V, Atanasova N, Wong A, Oudit GY, Epelman S, Kassiri Z
Progress on incorporating sex as a biological variable in cardiovascular research.
Lindsey ML, LeBlanc AJ, Ripplinger CM, Kassiri Z, Kirk JA, Kleinbongard P, Carter JR, Brunt KR
Cardioprotective effect of 19,20-epoxydocosapentaenoic acid (19,20-EDP) in ischaemic injury involves direct activation of mitochondrial sirtuin 3.
Darwesh AM, Fang L, Altamimi TR, Jamieson KL, Bassiouni W, Valencia R, Huang A, Wang F, Zhang H, Ahmed M, Gopal K, Zhang Y, Michelakis ED, Ussher JR, Edin ML, Zeldin DC, Barakat K, Oudit GY, Kassiri Z, Lopaschuk GD, Seubert JM
Inflammation in Abdominal Aortic Aneurysm: Cause or Comorbidity?
Zhu J, Meganathan I, MacAruthur R, Kassiri Z
Contribution of the arterial cells to atherosclerosis and plaque formation.
Naiya T, Meganathan I, Ness N, Oudit GY, Murray A, Kassiri Z
Loss of ADAM15 in female mice does not worsen pressure overload cardiomyopathy, independent of ovarian hormones.
Krishnan V, Atanasova N, Aujla PK, Hupka D, Owen CA, Kassiri Z
Modulation of endothelial cells to reduce plaque formation, independent from plasma cholesterol levels
Principal investigators: Kassiri, Zamaneh
Keywords: Atherosclerosis; Vascular Remodeling
Enriched hydrogel scaffold as a platform for cell and drug delivery to repair aortic aneurysm
Principal investigators: Kassiri, Zamaneh
Keywords: Aortic aneurysm; hydrogel matrix; cell-enriched hydrogel ; cell migration; tissue repair
Deciphering the role of ADAM15 vs. ADAM17 in fibroblast function: Mechanobiology vs. Proteolysis
Principal investigators: Kassiri, Zamaneh
Cell-specific role of ADAM17 in remodeling following myocardial infarction: identifying a therapeutic window
Principal investigators: Kassiri, Zamaneh
Keywords: Cell Culture; Disintegrin And Metalloproteinase; Fibrosis; Inflammation; Myocardial Infarction
Pathogenesis of COVID-19 mediated Cardiovascular Complications: Therapeutic Applications
Principal investigators: Oudit, Gavin Y
Keywords: Cytokines; Renin-Angiotesnin System; Sars-Cov-2
Canada Research Chair - Tier 1
Principal investigators: Kassiri, Zamaneh
Keywords: Crc
Regional specificity of aortic aneurym: Cell specific function of disintegrin and metalloprotease-17 (ADAM17) in thoracic versus abdominal aortic aneurysm
Principal investigators: Kassiri, Zamaneh
Keywords: Animal Models; Aortic Aneurysm; Endothelial Cells; Proteases; Smooth Muscle Cells; Vascular Remodeling
Role of ADAM15 in cardiac remodeling and heart failure: Discovery of its novel myocardial substrates
Principal investigators: Kassiri, Zamaneh
Keywords: Cardiac Pressure Overload; Cardiac Remodeling; Cell Biology; Disintegrin And Metalloproteases; Extracellular Matrix; Heart Disease; Molecular Biology; Mouse Models; Myocardial Infarction
Distinct functions and therapeutic potential of tissue inhibitor of metalloproteinases (TIMPs) in myocardial ischemia-reperfusion injury
Principal investigators: Kassiri, Zamaneh
Keywords: Extracellular Matrix; Ischemia-Reperfusion; Ischemic Heart Disease; Matrix Metalloproteinases; Myocardial Remodeling; Tissue Inhibitor Of Metalloproteinases
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Mahmoud Ali and Richard Schulz: 9 shared papers
- Richard Lehner and Zamaneh Kassiri: 4 shared papers
- Richard Schulz and Zamaneh Kassiri: 3 shared papers
- Slava Epelman and Zamaneh Kassiri: 3 shared papers
- Todd Anderson and Harald Becher: 2 shared papers
- Harald Becher and Zamaneh Kassiri: 2 shared papers
- Mahmoud Ali and Zamaneh Kassiri: 1 shared paper
- Gary Lopaschuk and Zamaneh Kassiri: 1 shared paper
- Richard Lehner and CHEOLHO Cheong: 1 shared paper
- Lori West and Zamaneh Kassiri: 1 shared paper
- Gavin Oudit and Zamaneh Kassiri: 1 shared paper
- Yves Sauve and Zamaneh Kassiri: 1 shared paper
- Boris Hinz and Zamaneh Kassiri: 1 shared paper
- CHEOLHO Cheong and Slava Epelman: 1 shared paper
- CHEOLHO Cheong and Zamaneh Kassiri: 1 shared paper
- Katey Rayner and Zamaneh Kassiri: 1 shared paper
- Todd Anderson and Zamaneh Kassiri: 1 shared paper
- Michel Bouvier and Zamaneh Kassiri: 1 shared paper
- Richard Schulz and Harald Becher: 1 shared paper
- Slava Epelman and Lindsey Westover: 1 shared paper
- Zamaneh Kassiri and Allan Murray: 1 shared paper
- Zamaneh Kassiri and Lindsey Westover: 1 shared paper
- Zamaneh Kassiri and Khaled Barakat: 1 shared paper
- Zamaneh Kassiri and Kyoung-Han Kim: 1 shared paper
- Pediatrics
- Medicine
- Physiology
- Pediatrics/Pharmacology
- Cardiology
- Matrix Dynamics Group
- Microbiologie et immunologie
- Other
Co-authors at University of Alberta, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Richard Lehner
Pediatrics
4 shared papers, latest 2017
Richard Schulz
Pediatrics/Pharmacology
3 shared papers, latest 2014
Slava Epelman
Cardiology
3 shared papers, latest 2026
Harald Becher
Faculty
2 shared papers, latest 2014
Allan Murray
Medicine
1 shared papers, latest 2024
Lindsey Westover
Mechanical Engineering
1 shared papers, latest 2026
Khaled Barakat
Faculty
1 shared papers, latest 2025
Kyoung-Han Kim
Cellular and Molecular Medicine
1 shared papers, latest 2020
Yves Sauve
Ophthalmology
1 shared papers, latest 2011
Boris Hinz
Matrix Dynamics Group
1 shared papers, latest 2016
Mahmoud Ali
Pathology & Molecular Medicine
1 shared papers, latest 2010
Katey Rayner
Biochemistry, Microbiology and Immunology
1 shared papers, latest 2021
Todd Anderson
Medicine/Cardiology
1 shared papers, latest 2014
Michel Bouvier
Biochimie et médecine moléculaire
1 shared papers, latest 2019
CHEOLHO Cheong
Microbiologie et immunologie
1 shared papers, latest 2015
Gary Lopaschuk
Pediatrics
1 shared papers, latest 2011
Lori West
Pediatrics
1 shared papers, latest 2023
Gavin Oudit
Medicine
1 shared papers, latest 2017
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