Faculty profile

Ian Tietjen

ResearcherSimon Fraser University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Simon Fraser University directory, so their courses may be missing. Find their university profile.

Ian Tietjen

Researcher

Simon Fraser University

Burnaby, British Columbia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
5 publications in the last five years, latest in 2024.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 1 research grant (1 SSHRC), most recently in 2018.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Virology HIV Molecular/Cellular Biology Natural products chemistry Medicinal plants Indigenous knowledge systems Virology, HIV, Molecular/Cellular Biology, Natural products chemistry, Medicinal plants, Indigenous knowledge systems

Latest papers

Medicinal Plant and Traditional Knowledge-guided Strategies to Combat HIV Persistence.
Current HIV/AIDS reports · 2024 · senior author
An ethnopharmacological survey of medicinal plants traditionally used by the BaKalanga people of the Tutume subdistrict in Central Botswana to manage HIV/AIDS, HIV-associated conditions, and other health conditions.
Journal of ethnopharmacology · 2023 · senior author
Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1: Preclinical Efficacy against Iron Overload and Safety Evaluation.
The Journal of pharmacology and experimental therapeutics · 2023

All 28 publications

Latest funding

Molecular, Chemical, and Community-Based Exploration of Indigenous Medicinal Plants
SSHRC · 2018 · Principal investigator
$273,310
Characterization of novel HIV-1 latency-modulating pure natural products
CIHR · 2016 · Co-investigator
$765,000

All 2 grants and awards

28 publications.

Medicinal Plant and Traditional Knowledge-guided Strategies to Combat HIV Persistence.

Richard K, Poli ANR, Andrae-Marobela K, Tietjen I

Current HIV/AIDS reports2024Senior author

DOI: 10.1007/s11904-024-00712-1 PMID: 39612046

An ethnopharmacological survey of medicinal plants traditionally used by the BaKalanga people of the Tutume subdistrict in Central Botswana to manage HIV/AIDS, HIV-associated conditions, and other health conditions.

Richard K, Andrae-Marobela K, Tietjen I

Journal of ethnopharmacology2023Senior author

DOI: 10.1016/j.jep.2023.116759 PMID: 37301306

Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1: Preclinical Efficacy against Iron Overload and Safety Evaluation.

Cutts A, Chowdhury S, Ratkay LG, Eyers M, Young C, Namdari R, Cadieux JA, Chahal N, Grimwood M, Zhang Z, Lin S, Tietjen I, Xie Z, Robinette L, Sojo L, Waldbrook M, Hayden M, Mansour T, Pimstone S, Goldberg YP, Webb M, Cohen CJ

The Journal of pharmacology and experimental therapeutics2023

DOI: 10.1124/jpet.122.001435 PMID: 36958846

The Natural Stilbenoid (-)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9.

Tietjen I, Schonhofer C, Sciorillo A, Naidu ME, Haq Z, Kannan T, Kossenkov AV, Rivera-Ortiz J, Mounzer K, Hart C, Gyampoh K, Yuan Z, Beattie KD, Rali T, Shuda McGuire K, Davis RA, Montaner LJ

Antimicrobial agents and chemotherapy2023First author

DOI: 10.1128/aac.01600-22 PMID: 36975214

Ansellone J, a Potent in Vitro and ex Vivo HIV-1 Latency Reversal Agent Isolated from a Phorbas sp. Marine Sponge.

Wang M, Sciorillo A, Read S, Divsalar DN, Gyampoh K, Zu G, Yuan Z, Mounzer K, Williams DE, Montaner LJ, de Voogd N, Tietjen I, Andersen RJ

Journal of natural products2022

DOI: 10.1021/acs.jnatprod.1c01225 PMID: 35522580

Flavonoid-based inhibition of cyclin-dependent kinase 9 without concomitant inhibition of histone deacetylases durably reinforces HIV latency.

Schonhofer C, Yi J, Sciorillo A, Andrae-Marobela K, Cochrane A, Harris M, Brumme ZL, Brockman MA, Mounzer K, Hart C, Gyampoh K, Yuan Z, Montaner LJ, Tietjen I

Biochemical pharmacology2021Senior author

DOI: 10.1016/j.bcp.2021.114462 PMID: 33577894

The African natural product knipholone anthrone and its analogue anthralin (dithranol) enhance HIV-1 latency reversal.

Richard K, Schonhofer C, Giron LB, Rivera-Ortiz J, Read S, Kannan T, Kinloch NN, Shahid A, Feilcke R, Wappler S, Imming P, Harris M, Brumme ZL, Brockman MA, Mounzer K, Kossenkov AV, Abdel-Mohsen M, Andrae-Marobela K, Montaner LJ, Tietjen I

The Journal of biological chemistry2020Senior author

DOI: 10.1074/jbc.ra120.013031 PMID: 32788215

Comatulins A-E, Taurine-Conjugated Anthraquinones from the Australian Crinoid Comatula rotalaria.

Lum KY, Taki AC, Gasser RB, Tietjen I, Ekins MG, White JM, Addison RS, Hayes S, St John J, Davis RA

Journal of natural products2020

DOI: 10.1021/acs.jnatprod.0c00267 PMID: 32478519

Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus.

Duncan MC, Onguéné PA, Kihara I, Nebangwa DN, Naidu ME, Williams DE, Balgi AD, Andrae-Marobela K, Roberge M, Andersen RJ, Niikura M, Ntie-Kang F, Tietjen I

Molecules (Basel, Switzerland)2020Senior author

DOI: 10.3390/molecules25122903 PMID: 32599753

Novel Histone Deacetylase Inhibitors and HIV-1 Latency-Reversing Agents Identified by Large-Scale Virtual Screening.

Divsalar DN, Simoben CV, Schonhofer C, Richard K, Sippl W, Ntie-Kang F, Tietjen I

Frontiers in pharmacology2020Senior author

DOI: 10.3389/fphar.2020.00905 PMID: 32625097

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Ian Tietjen

Research

Latest papers

Latest funding

Medicinal Plant and Traditional Knowledge-guided Strategies to Combat HIV Persistence.

An ethnopharmacological survey of medicinal plants traditionally used by the BaKalanga people of the Tutume subdistrict in Central Botswana to manage HIV/AIDS, HIV-associated conditions, and other health conditions.

Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1: Preclinical Efficacy against Iron Overload and Safety Evaluation.

The Natural Stilbenoid (-)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9.

Ansellone J, a Potent in Vitro and ex Vivo HIV-1 Latency Reversal Agent Isolated from a Phorbas sp. Marine Sponge.

Flavonoid-based inhibition of cyclin-dependent kinase 9 without concomitant inhibition of histone deacetylases durably reinforces HIV latency.

The African natural product knipholone anthrone and its analogue anthralin (dithranol) enhance HIV-1 latency reversal.

Comatulins A-E, Taurine-Conjugated Anthraquinones from the Australian Crinoid Comatula rotalaria.

Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus.

Novel Histone Deacetylase Inhibitors and HIV-1 Latency-Reversing Agents Identified by Large-Scale Virtual Screening.

Molecular, Chemical, and Community-Based Exploration of Indigenous Medicinal Plants

Characterization of novel HIV-1 latency-modulating pure natural products

Frequent collaborators

David Fedida

Masahiro Niikura

Michael Hayden

Michel Roberge

Simon Pimstone

Alan Cochrane

Brendan Bell

Ian Tietjen

Research

Latest papers

Latest funding

Medicinal Plant and Traditional Knowledge-guided Strategies to Combat HIV Persistence.

An ethnopharmacological survey of medicinal plants traditionally used by the BaKalanga people of the Tutume subdistrict in Central Botswana to manage HIV/AIDS, HIV-associated conditions, and other health conditions.

Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1: Preclinical Efficacy against Iron Overload and Safety Evaluation.

The Natural Stilbenoid (-)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-&#x3ba;B Signaling and Cyclin-Dependent Kinase 9.

Ansellone J, a Potent in Vitro and ex Vivo HIV-1 Latency Reversal Agent Isolated from a Phorbas sp. Marine Sponge.

Flavonoid-based inhibition of cyclin-dependent kinase 9 without concomitant inhibition of histone deacetylases durably reinforces HIV latency.

The African natural product knipholone anthrone and its analogue anthralin (dithranol) enhance HIV-1 latency reversal.

Comatulins A-E, Taurine-Conjugated Anthraquinones from the Australian Crinoid Comatula rotalaria.

Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus.

Novel Histone Deacetylase Inhibitors and HIV-1 Latency-Reversing Agents Identified by Large-Scale Virtual Screening.

Molecular, Chemical, and Community-Based Exploration of Indigenous Medicinal Plants

Characterization of novel HIV-1 latency-modulating pure natural products

Frequent collaborators

David Fedida

Masahiro Niikura

Michael Hayden

Michel Roberge

Simon Pimstone

Alan Cochrane

Brendan Bell

The Natural Stilbenoid (-)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9.