Faculty profile
Ging-Yuek Hsiung
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Research
Latest papers
Individualized Atrophy-Based Prediction of Dementia Progression in Familial Frontotemporal Lobar Degeneration With Bayesian Linear Mixed-Effects Modeling.
Annals of neurology · 2026
Regional effects of gantenerumab on neuroimaging biomarkers in the DIAN-TU-001 trial.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration.
JAMA network open · 2024
Latest funding
- $1,699,389
Alamar discovery of plasma biomarkers that distinguish dementia subtypes, inform on disease staging and predict rate of cognitive decline in Alzheimer's Disease and Related Dementias
CIHR · 2026 · Co-investigator
- $1,503,224
Evaluating the potential of blood biomarkers to improve Alzheimer's Disease risk stratification
CIHR · 2020 · Principal investigator
- $661,724
Sex Matters: Understanding Sex Differences in Exercise Efficacy on Brain Health in Mild Cognitive Impairment
CIHR · 2019 · Co-investigator
13 publications.
Individualized Atrophy-Based Prediction of Dementia Progression in Familial Frontotemporal Lobar Degeneration With Bayesian Linear Mixed-Effects Modeling.
Dutt S, Leichter D, Cobigo Y, Wolf A, Kornak J, Clark A, Russell LL, Bouzigues A, Cash DM, Bocchetta M, Olzinski M, Appleby B, Bayram E, Borroni B, Bozoki A, Butler CR, Clark D, Convery RS, Darby RR, de Mendonça A, Dickerson B, Domoto-Reilly K, Ducharme S, Ferry-Bolder E, Finger E, Foster PH, Galasko DR, Galimberti D, Gerhard A, Ghoshal N, Graff C, Graff-Radford N, Grant IM, Hales CM, Honig LS, Hsiung GY, Huey ED, Irwin D, Jiskoot LC, Kremers W, Kwan JY, Laforce R, Le Ber I, Léger GC, Levin J, Litvan I, Mackenzie IR, Masellis M, Mendez MF, Moreno F, Onyike C, Otto M, Pascual B, Pressman P, Rademakers R, Ramos EM, Ritter A, Roberson ED, Rowe JB, Sanchez-Valle R, Santana I, Seelaar H, Snyder A, Sorbi S, Synofzik M, Tartaglia MC, Tiraboschi P, van Swieten JC, Vandebergh M, Vandenberghe R, Heuer HW, Miller BL, Seeley WW, Gorno-Tempini ML, Kramer JH, Forsberg L, Kantarci K, Boeve BF, Boxer AL, Rohrer JD, Rosen HJ, Staffaroni AM, FTD Prevention Initiative (FPI) investigators
Regional effects of gantenerumab on neuroimaging biomarkers in the DIAN-TU-001 trial.
McCullough A, Chen CD, Gordon BA, Joseph-Mathurin N, Jack CR, Koeppe R, Hornbeck R, Koudelis D, McKay NS, Hobbs DA, Flores S, Keefe SJ, Aggarwal NT, Allegri RF, Berman SB, Bird T, Black SE, Brooks WS, Chhatwal JP, Day GS, Farlow MR, Fox NC, Gauthier S, Honig LS, Hsiung GY, Jucker M, Levin J, Masellis M, Masters C, Mendez PC, Ringman JM, Snider BJ, Salloway S, Schofield PR, Shimada H, Suzuki K, van Dyck CH, Klein G, Clifford DB, Cruchaga C, Hassenstab J, Li Y, McDade E, Mills S, Morris JC, Perrin RJ, Supnet-Bell C, Wang G, Xiong C, Bateman RJ, Benzinger TLS, DIAN‐TU Study Team
Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration.
Staffaroni AM, Clark AL, Taylor JC, Heuer HW, Sanderson-Cimino M, Wise AB, Dhanam S, Cobigo Y, Wolf A, Manoochehri M, Forsberg L, Mester C, Rankin KP, Appleby BS, Bayram E, Bozoki A, Clark D, Darby RR, Domoto-Reilly K, Fields JA, Galasko D, Geschwind D, Ghoshal N, Graff-Radford N, Grossman M, Hsiung GY, Huey ED, Jones DT, Lapid MI, Litvan I, Masdeu JC, Massimo L, Mendez MF, Miyagawa T, Pascual B, Pressman P, Ramanan VK, Ramos EM, Rascovsky K, Roberson ED, Tartaglia MC, Wong B, Miller BL, Kornak J, Kremers W, Hassenstab J, Kramer JH, Boeve BF, Rosen HJ, Boxer AL, ALLFTD Consortium
Temporal order of clinical and biomarker changes in familial frontotemporal dementia.
Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, VandeVrede L, Ljubenkov P, Kramer J, Casaletto KB, Appleby B, Bordelon Y, Botha H, Dickerson BC, Domoto-Reilly K, Fields JA, Foroud T, Gavrilova R, Geschwind D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Hall MGH, Hsiung GY, Huey ED, Irwin D, Jones DT, Kantarci K, Kaufer D, Knopman D, Kremers W, Lago AL, Lapid MI, Litvan I, Lucente D, Mackenzie IR, Mendez MF, Mester C, Miller BL, Onyike CU, Rademakers R, Ramanan VK, Ramos EM, Rao M, Rascovsky K, Rankin KP, Roberson ED, Savica R, Tartaglia MC, Weintraub S, Wong B, Cash DM, Bouzigues A, Swift IJ, Peakman G, Bocchetta M, Todd EG, Convery RS, Rowe JB, Borroni B, Galimberti D, Tiraboschi P, Masellis M, Finger E, van Swieten JC, Seelaar H, Jiskoot LC, Sorbi S, Butler CR, Graff C, Gerhard A, Langheinrich T, Laforce R, Sanchez-Valle R, de Mendonça A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, Le Ber I, Levin J, Danek A, Otto M, Pasquier F, Santana I, Kornak J, Boeve BF, Rosen HJ, Rohrer JD, Boxer AL, Frontotemporal Dementia Prevention Initiative (FPI) Investigators
Avoid or Embrace? Practice Effects in Alzheimer's Disease Prevention Trials.
Aschenbrenner AJ, Hassenstab J, Wang G, Li Y, Xiong C, McDade E, Clifford DB, Salloway S, Farlow M, Yaari R, Cheng EYJ, Holdridge KC, Mummery CJ, Masters CL, Hsiung GY, Surti G, Day GS, Weintraub S, Honig LS, Galvin JE, Ringman JM, Brooks WS, Fox NC, Snyder PJ, Suzuki K, Shimada H, Gräber S, Bateman RJ
Proposed research criteria for prodromal behavioural variant frontotemporal dementia.
Barker MS, Gottesman RT, Manoochehri M, Chapman S, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Domoto-Reilly K, Fields JA, Forsberg LK, Galasko DR, Ghoshal N, Goldman J, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GY, Knopman DS, Kornak J, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Pascual B, Staffaroni AM, Tartaglia MC, Boeve BF, Boxer AL, Rosen HJ, Rankin KP, Cosentino S, Rascovsky K, Huey ED, ALLFTD Consortium
Recognition memory and divergent cognitive profiles in prodromal genetic frontotemporal dementia.
Barker MS, Manoochehri M, Rizer SJ, Appleby BS, Brushaber D, Dev SI, Devick KL, Dickerson BC, Fields JA, Foroud TM, Forsberg LK, Galasko DR, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GY, Kornak J, Litvan I, Mackenzie IR, Mendez MF, Pascual B, Rankin KP, Rascovsky K, Staffaroni AM, Tartaglia MC, Weintraub S, Wong B, Boeve BF, Boxer AL, Rosen HJ, Goldman J, Huey ED, Cosentino S, ALLFTD consortium
Quality of life and caregiver burden in familial frontotemporal lobar degeneration: Analyses of symptomatic and asymptomatic individuals within the LEFFTDS cohort.
Gentry MT, Lapid MI, Syrjanen J, Calvert K, Hughes S, Brushaber D, Kremers W, Bove J, Brannelly P, Coppola G, Dheel C, Dickerson B, Dickinson S, Faber K, Fields J, Fong J, Foroud T, Forsberg L, Gavrilova R, Gearhart D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Haley D, Heuer H, Hsiung GY, Huey E, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Knopman D, Kornak J, Kramer J, Kukull W, Lucente D, Lungu C, Mackenzie I, Manoochehri M, McGinnis S, Miller B, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Sengdy P, Shaw L, Tatton N, Taylor J, Toga A, Trojanowski J, Weintraub S, Wong B, Wszolek Z, Boeve BF, Boxer A, Rosen H, LEFFTDS Consortium
Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.
Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ, ARTFL/LEFFTDS consortium
Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration.
Staffaroni AM, Cobigo Y, Goh SM, Kornak J, Bajorek L, Chiang K, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dever R, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Heuer HW, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kramer JH, Kremers WK, Kukull WA, Litvan I, Ljubenkov PA, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Rosen HJ, ARTFL/LEFFTDS consortium
Alamar discovery of plasma biomarkers that distinguish dementia subtypes, inform on disease staging and predict rate of cognitive decline in Alzheimer's Disease and Related Dementias
Principal investigators: Wellington, Cheryl L
Keywords: Alzheimer'S Disease; Biomarkers; Dementia; Immunoassay
Evaluating the potential of blood biomarkers to improve Alzheimer's Disease risk stratification
Principal investigators: Wellington, Cheryl L; Brooks-Wilson, Angela R; Chertkow, Howard M; Dixon, Roger A; Hsiung, Ging-Yuek R
Keywords: Alzheimer Disease; Blood Biomarker; Dementia; Early Detection; Risk Stratification
Sex Matters: Understanding Sex Differences in Exercise Efficacy on Brain Health in Mild Cognitive Impairment
Principal investigators: Liu-Ambrose, Teresa Y; Galea, Liisa A
Keywords: Aerobic Exercise; Biological Sex; Cognitive Function; Mild Cognitive Impairment; Randomized Controlled Trial
Diagnostic and predictive biomarkers for Frontotemporal Dementia with TDP-43 pathology
Principal investigators: Hsiung, Ging-Yuek R; Mackenzie, Ian R
Keywords: Fluid Biomarkers - Blood; Fluid Biomarkers - Csf; Frontotemporal Dementia; Imaging Biomarkers - Mri; Imaging Biomarkers - Pet; Neuropsychology; Tdp-43 Proteinopathy
In search of neuroimaging markers for neurodegeneration in presymptomatic frontotemporal dementia: A longitudinal study of genetically at-risk cohort
Principal investigators: Lee, Hyunwoo
Keywords: Biostatistics; Diffusion Tensor Imaging; Frontotemporal Dementia; Magnetic Resonance Imaging; Positron Emission Tomography
The Canadian ADNI BraIn Donation and Neuropathology Network (CABIN) - Optimizing Canadian Participation in the Neuropathology Program of ADNI
Principal investigators: Mackenzie, Ian R; Chertkow, Howard M; Hsiung, Ging-Yuek R
Keywords: Adni; Alzheimer'S Disease; Brain Banking; Dementia; Neuropathology
Novel non-invasive imaging of amyloid in the retina of the eye as a predictor of amyloid in the brain in Alzheimer's disease
Principal investigators: Campbell, Melanie
One size does not fit all: Tailoring exercise prescription for brain health based on BDNF polymorphism
Principal investigators: Liu-Ambrose, Teresa Y; Nagamatsu, Lindsay S
Keywords: Aerobic Exercise; Brain Derived Neurotrophic Factor Polymorph; Cognitive Function; Mild Cognitive Impairment; Neuroplasticity; Older Adults; Randomized Trial; Strength Training
Reshaping the Path of Mild Cognitive Impairment by Refining Exercise Prescription: Understanding Training Type and Exploring Mechanisms
Principal investigators: Liu-Ambrose, Teresa Y
Keywords: Biomarkers; Cognitive Function; Exercise; Mild Cognitive Impairment; Neuroimaging; Quality Of Life
Clinical, Pathological, Genetic and Biomarker Studies of Frontotemporal Dementia
Principal investigators: Mackenzie, Ian R; Feldman, Howard
Keywords: Amyotrophic Lateral Sclerosis; Biomarkers; C9orf72; Frontotemporal Dementia; Frontotemporal Lobar Degeneration; Natural History; Prodrome; Progranulin; Tdp-43
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Pathology and Laboratory Medicine
- Medicine
- Clinical Neurological Sciences
- Physical Therapy
- Mechanical Engineering
- Medicine/Neurology
- Neurology and Neurosurgery
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Mario Masellis
Medicine
3 shared papers, latest 2026
Elizabeth Finger
Clinical Neurological Sciences
2 shared papers, latest 2026
Teresa Liu-Ambrose
Physical Therapy
2 shared papers, latest 2019
Robert Laforce
Faculty
2 shared papers, latest 2026
Simon Ducharme
Faculty
2 shared papers, latest 2026
Ian Mackenzie
Medicine/Neurology
1 shared papers, latest 2020
Alexander Rauscher
Mechanical Engineering
1 shared papers, latest 2016
Serge Gauthier
Neurology and Neurosurgery
1 shared papers, latest 2025
Stirling Bryan
School of Population and Public Health
1 shared papers, latest 2016
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