Faculty profile

Harry Brumer

ResearcherMichael Smith LaboratoriesUniversity of British Columbia

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses may be missing. Find their university profile.

Harry Brumer

Researcher

Michael Smith Laboratories

Health Sciences

University of British Columbia

Vancouver, British Columbia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
26 publications in the last five years, latest in 2026.
Senior (last) author on 16 recent papers, a sign of leading a research group.
Principal investigator on 12 research grants (6 CIHR, 6 NSERC), most recently in 2024.
Supervisor on 1 trainee award (1 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

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Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Human Gut Microbiota Dietary Fibre Enzymology Carbohydrate Chemistry Enzyme Release Glycobiology Inflammatory Bowel Disease Prodrug

Latest papers

Exploring the biochemical and biological functions of copper radical oxidases in the vascular wilt phytopathogen Verticillium dahliae.
Applied and environmental microbiology · 2026 · senior author
Structural enzymology of a Fusarium graminearum aldehyde oxidase reveals a distinct active-site and reactivity versus its paralog galactose oxidase.
The Biochemical journal · 2026 · senior author
Conformational gating mechanism for processive catalysis of β(1,3)-glucans.
Nature communications · 2026

All 81 publications

Latest funding

Bespoke plant glycoconjugates to improve Inflammatory Bowel Disease treatment through gut-microbiota-mediated drug targeting
CIHR · 2024 · Principal investigator
$879,750
GlycoCaged drug delivery to improve Inflammatory Bowel Disease treatment
CIHR · 2024 · Nominated PI
$296,800
A systems based characterization of xyloglucan utilization by the human gut bacterium Segatella copri (syn. Prevotella copri)
CIHR · 2024 · Supervisor
$120,000

All 22 grants and awards

81 publications.

Exploring the biochemical and biological functions of copper radical oxidases in the vascular wilt phytopathogen Verticillium dahliae.

Fong JK, Chen Y-Y, Harting R, Klein M, Lewandowski S, Mathieu Y, Haon M, Bissaro B, Berrin J-G, Feussner I, Braus GH, Brumer H

Applied and environmental microbiology2026Senior author

DOI: 10.1128/aem.00790-26 PMID: 42233674

Structural enzymology of a Fusarium graminearum aldehyde oxidase reveals a distinct active-site and reactivity versus its paralog galactose oxidase.

Fong JK, Mazo L, Nairn AK, Lorizolla Cordeiro R, Mathieu Y, Chen YS, Rovira C, Walton PH, Van Petegem F, Brumer H

The Biochemical journal2026Senior author

DOI: 10.1042/bcj20260010 PMID: 41883256

Conformational gating mechanism for processive catalysis of β(1,3)-glucans.

Gimenis GHB, Spadeto JPM, Colombari FM, Miyamoto RY, Higasi PMR, Santos CA, Mandelli F, Martins MP, Araújo EA, Domingues MN, Fuzita FJ, Oliveira AM, Gazolla MC, Santos CR, Persinoti GF, Brumer H, Rovira C, Ramos CHI, Morais MAB, Murakami MT

Nature communications2026

DOI: 10.1038/s41467-026-71224-2 PMID: 41896250

Artificial cellulose derivatives are metabolized by select human gut Bacteroidota upon priming with common plant β-glucans.

Panwar D, Stewart WA, Rodd A, Brumer H

Journal of bacteriology2025Senior author

DOI: 10.1128/jb.00198-25 PMID: 40689633

Bespoke plant glycoconjugates for gut microbiota-mediated drug targeting.

Ma WJ, Wang C, Kothandapani J, Luzentales-Simpson M, Menzies SC, Bescucci DM, Lange ME, Fraser ASC, Gusse JF, House KE, Moote PE, Xing X, Grondin JM, Hui BW, Clarke ST, Shelton TG, Haskey N, Gibson DL, Martens EC, Abbott DW, Inglis GD, Sly LM, Brumer H

Science (New York, N.Y.)2025Senior author

DOI: 10.1126/science.adk7633 PMID: 40310938

Transcriptional delineation of polysaccharide utilization loci in the human gut commensal Segatella copri DSM18205 and co-culture with exemplar Bacteroides species on dietary plant glycans.

Panwar D, Briggs J, Fraser ASC, Stewart WA, Brumer H

Applied and environmental microbiology2025Senior author

DOI: 10.1128/aem.01759-24 PMID: 39636128

Origins of xyloglucan-degrading enzymes in fungi.

Trudeau ED, Brumer H, Berbee ML

The New phytologist2025

DOI: 10.1111/nph.20251 PMID: 39550623

The molecular basis of cereal mixed-linkage β-glucan utilization by the human gut bacterium Segatella copri.

Golisch B, Cordeiro RL, Fraser ASC, Briggs J, Stewart WA, Van Petegem F, Brumer H

The Journal of biological chemistry2024Senior author

DOI: 10.1016/j.jbc.2024.107625 PMID: 39122003

A scalable, chromatography-free, biocatalytic method to produce the xyloglucan heptasaccharide XXXG.

Rodd AM, Mawhinney WM, Brumer H

Biotechnology for biofuels and bioproducts2024Senior author

DOI: 10.1186/s13068-024-02563-9 PMID: 39164748

Expansion of Auxiliary Activity Family 5 sequence space via biochemical characterization of six new copper radical oxidases.

Fong JK, Mathieu Y, Vo MT, Bellemare A, Tsang A, Brumer H

Applied and environmental microbiology2024Senior author

DOI: 10.1128/aem.01014-24 PMID: 38953370

Bespoke plant glycoconjugates to improve Inflammatory Bowel Disease treatment through gut-microbiota-mediated drug targeting

Principal investigatorCIHR2024Project Grant

Principal investigators: Sly, Laura M; Brumer, Harry

Keywords: Carbohydrate Chemistry; Enzyme Release; Glycobiology; Human Gut Microbiota; Inflammatory Bowel Disease; Janus Kinase Inhibitors; Mouse Modelling; Prodrug; Steroids; Thiopurines

$879,750

GlycoCaged drug delivery to improve Inflammatory Bowel Disease treatment

Nominated PICIHR2024Cat Gr: Develop./validation of new biomedical techniques/technolo.- General Pool

Principal investigators: Brumer, Harry

Keywords: Carbohydrate Chemistry; Enzyme Release; Glycobiology; Human Gut Microbiota; Inflammatory Bowel Disease; Prodrug

$296,800

A systems based characterization of xyloglucan utilization by the human gut bacterium Segatella copri (syn. Prevotella copri)

SupervisorCIHR2024Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Stewart, William A

Keywords: Bacteroidota; Dietary Fiber; Human Gut Microbiome; Plant-Based Diet; Polysaccharide Utilization Loci; Prevotellaceae; Xyloglucan Utilization

$120,000

Dissecting the molecular basis of dietary fibre metabolism by beneficial Bacteroidetes of the human gut microbiota

Nominated PICIHR2023Project Grant

Principal investigators: Brumer, Harry

Keywords: Biochemistry; Carbohydrate-Active Enzymes; Carbohydrate-Binding Proteins; Complex Carbohydrates; Dietary Fibre; Enzymology; Human Gut Microbiota; Microbiology; Polysaccharide Utilization; Polysaccharide Utilization Loci

$1,086,300

Dissecting the molecular basis of dietary fibre metabolism by beneficial Bacteroidetes of the human gut microbiota

Nominated PICIHR2022Project Grant - PA: Nutrition, Metabolism and Diabetes

Principal investigators: Brumer, Harry

$100,000

Detecting Trace Metals in Synthetic and Biological Macromolecules. ICPMS for a Multi-User Facility in Chemistry

Co-investigatorNSERC2020Research Tools and Instruments

Principal investigators: Schafer, Laurel

$150,000

PRoTECT - Plant Responses To Eliminate Critical Threats: An NSERC-CREATE-DFG-IRTG joint training program to train the next generation of ""Plant Doctors""

Co-investigatorNSERC2018Collaborative Research and Training Experience

Principal investigators: Li, Xin

$1,650,000

Discovery, characterization, and application of carbohydrate-active enzymes from diverse biological niches

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Brumer, Harry

$588,000

400MHZ BROADBAND INVERSE DETECTION NMR SPECTROMETER

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Schafer, Laurel

$150,000

FUNTASTIC - Fungal copper-radical oxidases as new biocatalysts for the valorization of biomasscarbohydrates and alcohols

Principal investigatorNSERC2016Strategic Projects - Group

Principal investigators: Brumer, Harry

$690,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Harry Brumer

Research

Latest papers

Latest funding

Exploring the biochemical and biological functions of copper radical oxidases in the vascular wilt phytopathogen Verticillium dahliae.

Structural enzymology of a Fusarium graminearum aldehyde oxidase reveals a distinct active-site and reactivity versus its paralog galactose oxidase.

Conformational gating mechanism for processive catalysis of β(1,3)-glucans.

Artificial cellulose derivatives are metabolized by select human gut Bacteroidota upon priming with common plant β-glucans.

Bespoke plant glycoconjugates for gut microbiota-mediated drug targeting.

Transcriptional delineation of polysaccharide utilization loci in the human gut commensal Segatella copri DSM18205 and co-culture with exemplar Bacteroides species on dietary plant glycans.

Origins of xyloglucan-degrading enzymes in fungi.

The molecular basis of cereal mixed-linkage β-glucan utilization by the human gut bacterium Segatella copri.

A scalable, chromatography-free, biocatalytic method to produce the xyloglucan heptasaccharide XXXG.

Expansion of Auxiliary Activity Family 5 sequence space via biochemical characterization of six new copper radical oxidases.

Bespoke plant glycoconjugates to improve Inflammatory Bowel Disease treatment through gut-microbiota-mediated drug targeting

GlycoCaged drug delivery to improve Inflammatory Bowel Disease treatment

A systems based characterization of xyloglucan utilization by the human gut bacterium Segatella copri (syn. Prevotella copri)

Dissecting the molecular basis of dietary fibre metabolism by beneficial Bacteroidetes of the human gut microbiota

Dissecting the molecular basis of dietary fibre metabolism by beneficial Bacteroidetes of the human gut microbiota

Detecting Trace Metals in Synthetic and Biological Macromolecules. ICPMS for a Multi-User Facility in Chemistry

PRoTECT - Plant Responses To Eliminate Critical Threats: An NSERC-CREATE-DFG-IRTG joint training program to train the next generation of ""Plant Doctors""

Discovery, characterization, and application of carbohydrate-active enzymes from diverse biological niches

400MHZ BROADBAND INVERSE DETECTION NMR SPECTROMETER

FUNTASTIC - Fungal copper-radical oxidases as new biocatalysts for the valorization of biomasscarbohydrates and alcohols

Frequent collaborators

Filip Van Petegem

Alexei Savchenko

Alexei Savchenko

Emily Cranston

James Kronstad

Harry Brumer

Research

Latest papers

Latest funding

Exploring the biochemical and biological functions of copper radical oxidases in the vascular wilt phytopathogen Verticillium dahliae.

Structural enzymology of a Fusarium graminearum aldehyde oxidase reveals a distinct active-site and reactivity versus its paralog galactose oxidase.

Conformational gating mechanism for processive catalysis of &#x3b2;(1,3)-glucans.

Artificial cellulose derivatives are metabolized by select human gut Bacteroidota upon priming with common plant &#x3b2;-glucans.

Bespoke plant glycoconjugates for gut microbiota-mediated drug targeting.

Transcriptional delineation of polysaccharide utilization loci in the human gut commensal Segatella copri DSM18205 and co-culture with exemplar Bacteroides species on dietary plant glycans.

Origins of xyloglucan-degrading enzymes in fungi.

The molecular basis of cereal mixed-linkage &#x3b2;-glucan utilization by the human gut bacterium Segatella copri.

A scalable, chromatography-free, biocatalytic method to produce the xyloglucan heptasaccharide XXXG.

Expansion of Auxiliary Activity Family 5 sequence space via biochemical characterization of six new copper radical oxidases.

Bespoke plant glycoconjugates to improve Inflammatory Bowel Disease treatment through gut-microbiota-mediated drug targeting

GlycoCaged drug delivery to improve Inflammatory Bowel Disease treatment

A systems based characterization of xyloglucan utilization by the human gut bacterium Segatella copri (syn. Prevotella copri)

Dissecting the molecular basis of dietary fibre metabolism by beneficial Bacteroidetes of the human gut microbiota

Dissecting the molecular basis of dietary fibre metabolism by beneficial Bacteroidetes of the human gut microbiota

Detecting Trace Metals in Synthetic and Biological Macromolecules. ICPMS for a Multi-User Facility in Chemistry

PRoTECT - Plant Responses To Eliminate Critical Threats: An NSERC-CREATE-DFG-IRTG joint training program to train the next generation of ""Plant Doctors""

Discovery, characterization, and application of carbohydrate-active enzymes from diverse biological niches

400MHZ BROADBAND INVERSE DETECTION NMR SPECTROMETER

FUNTASTIC - Fungal copper-radical oxidases as new biocatalysts for the valorization of biomasscarbohydrates and alcohols

Frequent collaborators

Filip Van Petegem

Alexei Savchenko

Alexei Savchenko

Emily Cranston

James Kronstad

Conformational gating mechanism for processive catalysis of β(1,3)-glucans.

Artificial cellulose derivatives are metabolized by select human gut Bacteroidota upon priming with common plant β-glucans.

The molecular basis of cereal mixed-linkage β-glucan utilization by the human gut bacterium Segatella copri.