Faculty profile
Marcel Bally
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Research
Latest papers
A novel liposomal formulation of irinotecan comprising a combination of copper complexation and a transmembrane pH gradient to significantly improve irinotecan encapsulation and retention.
International journal of pharmaceutics · 2026 · senior author
Cryo-EM-guided subtractive optimization of a novel VCP/p97 inhibitor.
IUCrJ · 2026
Spatial characterization of redox processes and speciation of Ru(III) anticancer complexes by 19F magnetic resonance imaging.
Chemical communications (Cambridge, England) · 2023
Latest funding
- $1,028,926
Copper Associated Immunogenic Cell Death: Improving the Therapeutic Potential of Immune Check Point Inhibitors for the Treatment of Metastatic Bladder Cancer
CIHR · 2024 · Nominated PI
- $765,000
A Novel Formulation of the Anticancer Drug Candidate CX5461 that Relies on Metal Chemistry and Liposomal Nanotechnology: Development for use in Treatment of Pancreatic Cancer's with BRCA Deficiencies; an Orphan Indication
CIHR · 2021 · Nominated PI
- $1,070,300
Control of ER-mitochondria contacts and mitophagy by the Gp78 ubiquitin ligase: Role in tumor progression
CIHR · 2016 · Co-investigator
16 publications.
A novel liposomal formulation of irinotecan comprising a combination of copper complexation and a transmembrane pH gradient to significantly improve irinotecan encapsulation and retention.
Sun X, Sharifiaghdam M, Sarrami N, Popescu I, Wretham N, Santos ND, Sutherland B, Leung AWY, Redelmeier T, Abram M, Bally M
Cryo-EM-guided subtractive optimization of a novel VCP/p97 inhibitor.
Crawford J, Munuganti R, Leung C, Singh K, Gates E, Zhu X, Bally M, Santos ND, Sharifiaghdam M, Nosrati Z, Axerio-Cilies P, Berezuk AM, Cholak S, Merk A, Cameron DR, Subramaniam S
Spatial characterization of redox processes and speciation of Ru(III) anticancer complexes by 19F magnetic resonance imaging.
MacNeil GA, Chang SW, Prosser KE, Ye E, Heroux D, Lewis AR, Bally M, Walsby CJ
Ferrocene-appended anthraquinone and coumarin as redox-active cytotoxins.
Houshmand A, Heroux D, Liu DY, Zhou W, Linington RG, Bally M, Warren JJ, Walsby CJ
Gold-Protein Composite Nanoparticles for Enhanced X-ray Interactions: A Potential Formulation for Triggered Release.
van Ballegooie C, Man A, Pallaoro A, Bally M, Gates BD, Yapp DT
Inter-Metastatic Heterogeneity of Tumor Marker Expression and Microenvironment Architecture in a Preclinical Cancer Model.
Kalra J, Baker J, Song J, Kyle A, Minchinton A, Bally M
Preparation of parenteral nanocrystal suspensions of etoposide from the excipient free dry state of the drug to enhance in vivo antitumoral properties.
Martin B, Seguin J, Annereau M, Fleury T, Lai-Kuen R, Neri G, Lam A, Bally M, Mignet N, Corvis Y
Concomitant Chemoradiation Therapy with Gold Nanoparticles and Platinum Drugs Co-Encapsulated in Liposomes.
Charest G, Tippayamontri T, Shi M, Wehbe M, Anantha M, Bally M, Sanche L
The cyanobacterial metabolite nocuolin a is a natural oxadiazine that triggers apoptosis in human cancer cells.
Voráčová K, Hájek J, Mareš J, Urajová P, Kuzma M, Cheel J, Villunger A, Kapuscik A, Bally M, Novák P, Kabeláč M, Krumschnabel G, Lukeš M, Voloshko L, Kopecký J, Hrouzek P
Precision autophagy: Will the next wave of selective autophagy markers and specific autophagy inhibitors feed clinical pipelines?
Lebovitz CB, DeVorkin L, Bosc D, Rothe K, Singh J, Bally M, Jiang X, Young RN, Lum JJ, Gorski SM
Copper Associated Immunogenic Cell Death: Improving the Therapeutic Potential of Immune Check Point Inhibitors for the Treatment of Metastatic Bladder Cancer
Principal investigators: Bally, Marcel B; Evgin, Laura E
Keywords: Cancer; Combinations; Copper; Icd-Immunogenic Cell Death; Immune Check Point Inhibitors (Cpis); Immunotherapy; Liposomes; Metal Chemistry; Metastatic Bladder Cancer (Mblc); Small Molecules
A Novel Formulation of the Anticancer Drug Candidate CX5461 that Relies on Metal Chemistry and Liposomal Nanotechnology: Development for use in Treatment of Pancreatic Cancer's with BRCA Deficiencies; an Orphan Indication
Principal investigators: Bally, Marcel B
Keywords: Brca Deficiencies; Cx5461; Drug Development; Liposomes; Metal Chemistry; Mice; Pancreatic Cancer Efficacy Models; Preclinical; Safety Pharmacology; Skin Toxicity
Control of ER-mitochondria contacts and mitophagy by the Gp78 ubiquitin ligase: Role in tumor progression
Principal investigators: Nabi, Ivan R
Keywords: Autophagy; Breast Cancer; Endoplasmic Reticulum Stress; Endoplasmic Reticulum-Mitochondria Contacts; Fluorescent Microscopy; Mitochondrial Dynamics; Mitophagy; Reactive Oxygen Species; Tumor Progression
Copper Drug Complexes: Development of a novel class of drugs with significant potential for treatment of platinum insensitive cancers
Principal investigators: Bally, Marcel B
Keywords: Anticancer Drugs; Copper; Drug Development; Formulation Development; Liposomes; Metal Complexes; Pharmacodynamics; Pharmacokinetics; Platinum Insensitive; Repurposing
Targeted radiopharmaceuticals to improve cancer diagnosis and treatment
Principal investigators: Benard, Francois
Keywords: Breast Cancer; Molecular Imaging; Nuclear Medicine; Positron Emission Tomography; Prostate Cancer; Radioisotopes; Radionuclide Therapy; Radiopharmaceuticals
Preclinical evaluation of a gentamicin analog as a treatment for genetic diseases and cancer due to a premature termination codon.
Principal investigators: Roberge, Michel
Keywords: Aminoglycosides; Animal Studies; Cancer; New Therapeutics; Nonsense Mutations; Premature Stop Codon Readthrough; Rare Genetic Diseases; Tp53; Tumour Xenografts
The biology and clinical significance of the tumour microenvironment in B cell lymphomas
Principal investigators: Steidl, Christian
Keywords: Biomarker; Cancer; Genomics; Immune Biology; Lymphoma; Microenvironment; Molecular Genetics; Pathogenesis; Treatment Outcome
Lipid nanomedicines for health and disease
Principal investigators: Cullis, Pieter R
Keywords: Anticancer; Drug Delivery System; Gene Therapy; Immunosuppressant; Lipid Nanoparticles; Mrna; Nanomedicine; Sirna; Small Molecule Drugs; Trigger Release
Simultaneous chemotherapy and radiation treatment in solid tumours: A new platform to promote synergy and therapeutic efficacy with radiation triggered drug release
Principal investigators: Gates, Byron
Somatic mutations in the JAK-STAT signaling pathway in primary mediastinal large B cell lymphoma
Principal investigators: Steidl, Christian
Keywords: Cellular Signaling; Genomics; Non-Hodgkin Lymphoma; Outcome Prediction; Pathobiology; Somatic Mutations; Therapeutics
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Experimental Therapeutics
- Biochemistry and Molecular Biology
- Cellular and Physiological Sciences
- Molecular Oncology
- Terry Fox Laboratory
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Shoukat Dedhar
Biochemistry and Molecular Biology
2 shared papers, latest 2011
Andrew Minchinton
Faculty
2 shared papers, latest 2021
Sriram Subramaniam
Faculty
1 shared papers, latest 2026
David Huntsman
Molecular Oncology
1 shared papers, latest 2011
Calvin Roskelley
Cellular and Physiological Sciences
1 shared papers, latest 2011
Xiaoyan Jiang
Terry Fox Laboratory
1 shared papers, latest 2015
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