Faculty profile
Peter Stirling
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Research
Latest papers
The UVA-induced single-base mutational signature of CX-5461 in human cells.
Nucleic acids research · 2026
Mapping of DDX11 genetic interactions defines sister chromatid cohesion as the major dependency.
G3 (Bethesda, Md.) · 2024
ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork.
Nucleic acids research · 2020
Latest funding
- $948,600
Identification of novel DNA nuclease inhibition strategies
CIHR · 2025 · Nominated PI
- $120,000
Characterizing DNA repair deficient cancers benefiting from pol-z inhibition
CIHR · 2025 · Supervisor
- $10,000
7th Canadian Symposium on Telomeres and Genome Integrity
CIHR · 2025 · Co-investigator
3 publications.
The UVA-induced single-base mutational signature of CX-5461 in human cells.
Zaikova E, Yap D, Sarvar A, Hafezi A, Tan J, Cerda V, Li K, Lai D, Gelmon K, Hilton J, Seymour L, Stirling P, Cescon DW, Aparicio S
Mapping of DDX11 genetic interactions defines sister chromatid cohesion as the major dependency.
Amitzi L, Cozma E, Tong AHY, Chan K, Ross C, O'Neil N, Moffat J, Stirling P, Hieter P
ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork.
Kim S, Kang N, Park SH, Wells J, Hwang T, Ryu E, Kim BG, Hwang S, Kim SJ, Kang S, Lee S, Stirling P, Myung K, Lee KY
Identification of novel DNA nuclease inhibition strategies
Principal investigators: Stirling, Peter C
Keywords: Cancer; Dna Damage; Dna Repair; Dna Replication; Dominant Negative; Homologous Recombination; Medicinal Chemistry; Nucleases; Small Molecule Inhibitors; Yeast
Characterizing DNA repair deficient cancers benefiting from pol-z inhibition
Principal investigators: Cozma, Ecaterina
Keywords: Dna Damage Repair; Genome Instability; Synthetic Lethality; Translesion Synthesis Polymerases
7th Canadian Symposium on Telomeres and Genome Integrity
Principal investigators: Cobb, Jennifer A
Keywords: Aging; Canadian Scientific Symposium; Cancer; Carcinogens; Dna Damage Repair; Dna Replication And Mitosis; Genome Stability; Nuclear Organization; Rare Disease; Telomeres
Development and application of novel FEN1 endonuclease inhibitors
Principal investigators: Stirling, Peter C
Keywords: Biochemistry; Dna Repair; Fbxw7; Fen1; Glioblastoma; Homologous Recombination Deficiency; Small Molecule Inhibitor
Identification of novel DNA nuclease inhibition strategies
Principal investigators: Stirling, Peter C
Keywords: Cancer; Dna Damage; Dna Repair; Dna Replication; Dominant Negative; Homologous Recombination; Nucleases; Yeast
Targeting the translesion synthesis pathway as a potential therapeutic strategy in chemoresistant and late stage cancers
Principal investigators: White, Justin M
Keywords: Cancer Therapy; Chemoresistance; Dna Repair; Ics Travel Awards; Synthetic Lethality
Dominant genetics of cohesin pathway proteins to kill cancer
Principal investigators: Stirling, Peter C
Keywords: Dominant Genetics; Genome Instability; Missense Mutations; Mutational Scanning; Protein Trapping; Smc Atpases; Synthetic Lethality
Molecular and Functional Genomic Characterization of G-quadruplex in Cancers with the Alternate Lengthening of Telomere (ALT) Mechanism
Principal investigators: Wong, Judy M
Keywords: Alternate Lengthening Of Telomere; G-Quadruplexes; R-Loop; Synthetic Lethality; Terra
Protein trapping for therapeutic targeting of WRN in cancers with microsatellite instability.
Principal investigators: Baillie, Katherine E
Keywords: Cancer Therapy; Crispr-Cas9; Dna Damage Response; Microsatellite Instability; Protein Trapping; Synthetic Lethality; Wrn Helicase
Nuclear protein quality control mechanisms during genotoxic stress
Principal investigators: Stirling, Peter
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Terry Fox Laboratory
- Genetics and Genome Biology
- Department of Medicine
- Michael Smith Laboratories
- Molecular Oncology
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Jason Moffat
Genetics and Genome Biology
1 shared papers, latest 2024
Lesley Seymour
Faculty
1 shared papers, latest 2026
John Hilton
Department of Medicine
1 shared papers, latest 2026
Samuel Aparicio
Molecular Oncology
1 shared papers, latest 2026
Philip Hieter
Michael Smith Laboratories
1 shared papers, latest 2024
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