Tao Huan, University of British Columbia

Research

Metabolomics Bioinformatics liquid chromatography-mass spectrometry Lipidomics Metabolite identification Metabolomic data preprocessing Multi-omic integration Systems biology

Latest papers

Diversity of Iodinated Water Disinfection Byproducts and Their Formation Dynamics Discovered Using Exposome-Scale Nontargeted Analysis and Machine Learning.
Environmental science & technology · 2026
BAGO: A Self-Optimizing Tool for LC-MS Gradient Design in Metabolomics.
Analytical chemistry · 2026 · senior author
Pilot longitudinal integrated transcriptomic-metabolomic study reveals immune and metabolic signatures in non-hospitalized healthcare workers with long COVID.
Frontiers in cellular and infection microbiology · 2026

All 99 publications

Latest funding

Multi-omics plasma biomarkers for early detection of cardiac allograft vasculopathy in adult heart transplant recipients
CIHR · 2025 · Co-investigator
$780,300
The Toxic Drug Study: Clinical and toxicological profiles of people with unregulated drug poisoning.
CIHR · 2025 · Co-investigator
$1,602,675
Metabolomic biomarkers for early detection of acute cellular rejection in heart transplant recipients: a multidisciplinary approach to improve diagnostic accuracy and patient outcomes
CIHR · 2024 · Co-investigator
$229,500

All 8 grants and awards

99 publications.

01

Diversity of Iodinated Water Disinfection Byproducts and Their Formation Dynamics Discovered Using Exposome-Scale Nontargeted Analysis and Machine Learning.

Shen Q, Zhang D, Zhao T, Chau KNM, Grubisa G, Huan T, Le XC, Li XF

Environmental science & technology2026

DOI: 10.1021/acs.est.6c03869 PMID: 42359529

02

BAGO: A Self-Optimizing Tool for LC-MS Gradient Design in Metabolomics.

Yu H, Biswas P, Rideout E, Cao Y, Fiehn O, Huan T

Analytical chemistry2026Senior author

DOI: 10.1021/acs.analchem.6c01208 PMID: 42294915

03

Pilot longitudinal integrated transcriptomic-metabolomic study reveals immune and metabolic signatures in non-hospitalized healthcare workers with long COVID.

Espín E, Yang C, Shannon CP, Checkervarty AK, Kim S, Lapp L, Assadian S, Grunau B, Goldfarb DM, Hutton J, Huan T, Tebbutt SJ

Frontiers in cellular and infection microbiology2026

DOI: 10.3389/fcimb.2026.1808564 PMID: 42328163

04

The Multifaceted Challenge of Normalizing Mass Spectrometry-Based Metabolomics Data.

Low B, Nguyen C, Huan T

Analytical chemistry2026Senior author

DOI: 10.1021/acs.analchem.6c00292 PMID: 42081666

05

Disentangling method-induced differences in metabolomics: single- versus dual-phase extraction.

Kim SE, Huan T

The Analyst2026Senior author

DOI: 10.1039/d6an00025h PMID: 41982164

06

Disinfection Byproducts in the Long-Tail Exposome: Unmet Challenges for Water Quality and Human Health.

Huan T, Li XF

Environmental science & technology2026First author

DOI: 10.1021/acs.est.6c05202 PMID: 42060795

07

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis.

Manceau R, Cherian CM, Majeur D, Miller CJ, Fisher JD, Boisjoly F, Liston JB, Bako JA, Wat LW, Chao CF, Labarre A, Hollman S, Prakash S, Audet S, Depaauw-Holt L, Rogers B, Bosson A, Biswas P, Xi JJY, Callow CAS, Yoosefi N, Schikora N, Shahraki N, Xia YH, Hui A, VanderZwaag J, Bouyakdan K, Rodaros D, Kotchetkov P, Daneault C, Fallahpour G, Tetreault M, Tremblay MÈ, Ruiz M, Lacoste B, Parker JA, Murphy-Royal C, Huan T, Fulton S, Rideout EJ, Alquier T

Nature metabolism2026

DOI: 10.1038/s42255-026-01508-w PMID: 41981110

08

Data-Driven Discovery of Unknown Precursors of N-Nitrosodimethylamine in Nontargeted Liquid Chromatography-High Resolution Mass Spectrometry Analysis.

Gao M, Zhao T, Liao X, Huan T, Shen Q, Chau KNM, Zhang D, Chen Z, Ma H, Li XF

Environmental science & technology2026

DOI: 10.1021/acs.est.5c10336 PMID: 41714108

09

AminoacidDB: a liquid chromatography-tandem mass spectrometry-based toolkit for the untargeted analysis of non-protein amino acids.

Sandhu PK, Giebelhaus RT, Hayward R, Zhao T, Tucker A, Gaudet D, Huan T, Murch SJ

The Analyst2026

DOI: 10.1039/d5an01248a PMID: 41543071

10

Maternal Sucrose Intake during Pregnancy Alone Disrupts Testosterone and Allopregnanolone Levels in the Fetal Brain of Rats.

Jung MM, Idrissi M, Hoang YN, Huan T, Seib DR, Soma KK

The Journal of nutrition2026

DOI: 10.1016/j.tjnut.2025.101267 PMID: 41386554

Multi-omics plasma biomarkers for early detection of cardiac allograft vasculopathy in adult heart transplant recipients

Co-investigatorCIHR2025Project Grant

Principal investigators: Tebbutt, Scott J

Keywords: Biomarkers; Cardiac Allograft Vasculopathy; Heart Transplantation; Metabolomics; Proteomics

$780,300

The Toxic Drug Study: Clinical and toxicological profiles of people with unregulated drug poisoning.

Co-investigatorCIHR2025Project Grant

Principal investigators: Brubacher, Jeffrey R

Keywords: Fentanyl; Opioids; Overdose; Sedatives; Stimulants; Toxicology; Unregulated Drugs

$1,602,675

Metabolomic biomarkers for early detection of acute cellular rejection in heart transplant recipients: a multidisciplinary approach to improve diagnostic accuracy and patient outcomes

Co-investigatorCIHR2024Project Grant

Principal investigators: Tebbutt, Scott J

Keywords: Acute Cellular Rejection; Heart Transplantation; Metabolomic Biomarkers

$229,500