William Jia, University of British Columbia

Research

Metastasis Mirna Oncolytic Virus Prostate Cancer Therapy Xenograft

Latest papers

Publisher Correction: Beyond cold to hot: oncolytic virotherapy as the next cornerstone of immuno-oncology.
Nature reviews. Clinical oncology · 2026 · first author
Beyond cold to hot: oncolytic virotherapy as the next cornerstone of immuno-oncology.
Nature reviews. Clinical oncology · 2026 · first author
Publisher Correction: Oncolytic virus VG161 in refractory hepatocellular carcinoma.
Nature · 2025

All 46 publications

Latest funding

An "Inducible" Gene Therapy for Glaucoma: A Novel Approach to Prevent Loss of Vision
CIHR · 2016 · Co-investigator
$975,375
Identification of miRNAs and their Specific Gene Targets that are Critical for Prostate Cancer Metastases
CIHR · 2012 · Principal investigator
$775,000
Activation of Metalloproteinases in AMD - A Novel Strategy for Treatment
CIHR · 2012 · Co-investigator
$656,303

All 5 grants and awards

46 publications.

01

Publisher Correction: Beyond cold to hot: oncolytic virotherapy as the next cornerstone of immuno-oncology.

Jia W, Zhao R, Kaufman HL, Martuza RL

Nature reviews. Clinical oncology2026First author

DOI: 10.1038/s41571-026-01205-3 PMID: 42728388

02

Beyond cold to hot: oncolytic virotherapy as the next cornerstone of immuno-oncology.

Jia W, Zhao R, Kaufman HL, Martuza RL

Nature reviews. Clinical oncology2026First author

DOI: 10.1038/s41571-026-01198-z PMID: 42693190

03

Publisher Correction: Oncolytic virus VG161 in refractory hepatocellular carcinoma.

Shen Y, Bai X, Zhang Q, Liang X, Jin X, Zhao Z, Song W, Tan Q, Zhao R, Jia W, Gu S, Shi G, Zheng Z, Wei G, Wang Y, Fang T, Li Y, Wang Z, Yang Z, Guo S, Lin D, Wei F, Wang L, Sun X, Qin A, Xie L, Qiu Y, Bao W, Rahimian S, Singh M, Murad Y, Shang J, Chu M, Huang M, Ding J, Chen W, Ye Y, Chen Y, Li X, Liang T

Nature2025

DOI: 10.1038/s41586-025-09022-x PMID: 40269171

04

Oncolytic virus VG161 in refractory hepatocellular carcinoma.

Shen Y, Bai X, Zhang Q, Liang X, Jin X, Zhao Z, Song W, Tan Q, Zhao R, Jia W, Gu S, Shi G, Zheng Z, Wei G, Wang Y, Fang T, Li Y, Wang Z, Yang Z, Guo S, Lin D, Wei F, Wang L, Sun X, Qin A, Xie L, Qiu Y, Bao W, Rahimian S, Singh M, Murad Y, Shang J, Chu M, Huang M, Ding J, Chen W, Ye Y, Chen Y, Li X, Liang T

Nature2025

DOI: 10.1038/s41586-025-08717-5 PMID: 40108464

05

A Novel Self-Amplifying mRNA with Decreased Cytotoxicity and Enhanced Protein Expression by Macrodomain Mutations.

Gong Y, Yong D, Liu G, Xu J, Ding J, Jia W

Advanced science (Weinheim, Baden-Wurttemberg, Germany)2024Senior author

DOI: 10.1002/advs.202402936 PMID: 39313862

06

The effect of smoking on chronic inflammation, immune function and blood cell composition.

Elisia I, Lam V, Cho B, Hay M, Li MY, Yeung M, Bu L, Jia W, Norton N, Lam S, Krystal G

Scientific reports2020

DOI: 10.1038/s41598-020-76556-7 PMID: 33173057

07

Oncolytic virotherapy in hepato-bilio-pancreatic cancer: The key to breaking the log jam?

Li Y, Shen Y, Zhao R, Samudio I, Jia W, Bai X, Liang T

Cancer medicine2020

DOI: 10.1002/cam4.2949 PMID: 32130786

08

Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk.

Elisia I, Lam V, Cho B, Hay M, Li MY, Kapeluto J, Elliott T, Harris D, Bu L, Jia W, Leung H, Mohn W, Krystal G

PloS one2020

DOI: 10.1371/journal.pone.0228633 PMID: 32027700

09

UV Light-inactivated HSV-1 Stimulates Natural Killer Cell-induced Killing of Prostate Cancer Cells.

Samudio I, Hofs E, Cho B, Li M, Bolduc K, Bu L, Liu G, Lam V, Rennie P, Jia W, Elisia I, Krystal G

Journal of immunotherapy (Hagerstown, Md. : 1997)2019

DOI: 10.1097/cji.0000000000000261 PMID: 30933043

10

A TRAMP-derived orthotopic prostate syngeneic (TOPS) cancer model for investigating anti-tumor treatments.

Lardizabal J, Ding J, Delwar Z, Rennie PS, Jia W

The Prostate2018Senior author

DOI: 10.1002/pros.23490 PMID: 29450905

An "Inducible" Gene Therapy for Glaucoma: A Novel Approach to Prevent Loss of Vision

Co-investigatorCIHR2016Project Grant

Principal investigators: Matsubara, Joanne A

Keywords: Gene Therapy For Glaucoma; Glaucoma; Glaucoma Pathophysiology; Glaucoma Treatment

$975,375

Identification of miRNAs and their Specific Gene Targets that are Critical for Prostate Cancer Metastases

Principal investigatorCIHR2012Operating Grant

Principal investigators: Wang, Yuzhuo; Collins, Colin C; Jia, William W; Rennie, Paul S

Keywords: Metastasis; Mirna; Oncolytic Virus; Prostate Cancer; Therapy; Xenograft

$775,000

Activation of Metalloproteinases in AMD - A Novel Strategy for Treatment

Co-investigatorCIHR2012Operating Grant

Principal investigators: Matsubara, Joanne A

Keywords: Age-Related Macular Degeneration; Amyloid Beta; Drusen; Fractalkine; Geographic Atrophy; Inflammation; Photoreceptors; Proteases; Rpe; Tnf-A

$656,303

A virus-based strategy for measurement of circulating tumour cells

Co-investigatorCIHR2012Operating Grant

Principal investigators: Rennie, Paul S

Keywords: Castration-Resistant; Circulating Tumour Cells; Metastases; Oncolytic Virus; Prostate Cancer; Targeting

$352,260

The Terry Fox New Frontiers Program on Prostate Cancer Progression (M. Gleave)

Co-investigatorCIHR2010Team Grant: Terry Fox New Frontiers Program in Cancer

Principal investigators: Gleave, Martin E; Chi, Kim N; Collins, Colin C; Cox, Michael E; Guns, Emma S; Ong, Christopher J; Rennie, Paul S; Wang, Yuzhuo

Keywords: Genomic Markers; Prostate Cancer; Targeted Therapies; Translational Research

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Urologic Sciences
Experimental Therapeutics
Genome Sciences Centre
Pathology and Laboratory Medicine
Surgery
Terry Fox Laboratory
Biomedical Engineering
Other

Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Lynn Raymond

Psychiatry

1 shared papers, latest 2011

Wolfram Tetzlaff

Zoology

1 shared papers, latest 2016

Fumio Takei

Terry Fox Laboratory

1 shared papers, latest 2016

Angela Brooks-Wilson

Genome Sciences Centre

1 shared papers, latest 2017

Aziz Ghahary

Surgery

1 shared papers, latest 2016

Stephen Lam

Faculty

1 shared papers, latest 2020

William Mohn

Microbiology and Immunology

1 shared papers, latest 2020

Michael Cox

Urologic Sciences

1 shared papers, latest 2010

Martin Gleave

Urologic Sciences

1 shared papers, latest 2006

Larry Goldenberg

Biomedical Engineering

1 shared papers, latest 2006

Angela Brooks-Wilson

Pathology and Laboratory Medicine

1 shared papers, latest 2017

Christopher Ong

Urologic Sciences

1 shared papers, latest 2010

Artem Cherkasov

Urologic Sciences

1 shared papers, latest 2018

Paul Rennie

Urologic Sciences

1 shared papers, latest 2019

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Subject: Prospective PhD student: Metastasis Dear Professor Jia, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Publisher Correction: Beyond cold to hot: oncolytic virotherapy as the next cornerstone of immuno-oncology." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]