This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.
Latest papers
Author Correction: SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.
Nature communications · 2023
SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.
Nature communications · 2021
HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.
Oncogene · 2021
Latest funding
- $1,147,500
Identifying mediators of drug tolerance and persister cell survival in response to targeted therapies in lung adenocarcinoma
CIHR · 2026 · Nominated PI
- $120,000
Identifying Novel Cooperators of EGFR Induced Tumourigenesis in Lung Adenocarcinoma
CIHR · 2025 · Supervisor
- $1,500
PM2.5 shapes the mutational and epigenetic profiles of lung adenocarcinoma patients who have never smoked
CIHR · 2025 · Supervisor
5 publications.
Author Correction: SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.
Xue Y, Morris JL, Yang K, Fu Z, Zhu X, Johnson F, Meehan B, Witkowski L, Yasmeen A, Golenar T, Coatham M, Morin G, Monast A, Pilon V, Fiset PO, Jung S, Gonzalez AV, Camilleri-Broet S, Fu L, Postovit LM, Spicer J, Gotlieb WH, Guiot MC, Rak J, Park M, Lockwood W, Foulkes WD, Prudent J, Huang S
SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.
Xue Y, Morris JL, Yang K, Fu Z, Zhu X, Johnson F, Meehan B, Witkowski L, Yasmeen A, Golenar T, Coatham M, Morin G, Monast A, Pilon V, Fiset PO, Jung S, Gonzalez AV, Camilleri-Broet S, Fu L, Postovit LM, Spicer J, Gotlieb WH, Guiot MC, Rak J, Park M, Lockwood W, Foulkes WD, Prudent J, Huang S
HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.
Turgu B, Zhang F, El-Naggar A, Negri GL, Kogler M, Tortola L, Johnson F, Ng T, Li A, Yapp D, Lockwood W, Martinez D, Maris JM, Daugaard M, Penninger JM, Hughes CS, Sorensen PH
Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors.
Ayeni D, Miller B, Kuhlmann A, Ho PC, Robles-Oteiza C, Gaefele M, Levy S, de Miguel FJ, Perry C, Guan T, Krystal G, Lockwood W, Zelterman D, Homer R, Liu Z, Kaech S, Politi K
Multi-scale system biology applied to cervical inter-epithelial neoplasia.
Thiberville C, Guillaud M, Lockwood W, Lam W, Follen M, MacAulay C
Identifying mediators of drug tolerance and persister cell survival in response to targeted therapies in lung adenocarcinoma
Principal investigators: Lockwood, William W
Keywords: Drug Resistance; Drug Tolerance; Egfr; Functional Genomics; Kras; Lung Cancer; Mouse Models; Targeted Therapy
Identifying Novel Cooperators of EGFR Induced Tumourigenesis in Lung Adenocarcinoma
Principal investigators: Jajarmi, Jana
Keywords: Crispr; Drug Resistance; Lung Adenocarcinoma; Target Identification; Tumourigenesis
PM2.5 shapes the mutational and epigenetic profiles of lung adenocarcinoma patients who have never smoked
Principal investigators: Wang, Peiyao
Keywords: Ics Travel Awards
Investigating SNF2 Histone Linker PHD RING Helicase (SHPRH) as a Risk Factor for Lung Cancer Initiation and Development
Principal investigators: Chuang, Yu-Chi (Serena)
Keywords: Cancer Genetics; Carcinogens; Environmental Pollution; Genetic Susceptibility; Lung Cancer; Protein Interactions; Rna-Sequencing; Smoking; Tumour Suppressor
SNF2 Histone Linker PHD RING Helicase as a novel tumor suppressor gene and risk factor in lung adenocarcinoma development
Principal investigators: Lockwood, William W
Keywords: Cancer Biology; Cancer Risk; Cancer Screening; Dna Damage; Early Detection; Genomics; Lung Cancer; Molecular Biology; Mouse Models; Targeted Therapy
Targeting lung microbiome for developing early detection and intervention strategies for lung cancer
Principal investigators: Lam, Wan L
Keywords: Early Detection; Lung Cancer; Microbiome; Molecular Biology
Investigating the biological effects of environmental air pollution on lung cancer in never smokers using an integrated genomics approach
Principal investigators: Wang, Peiyao
Keywords: Air Pollution; Fine Particulate Matter; Immune-Tumour Microenvironment; Integrative Genomics; Lung Cancer; Mutational Signatures; Never Smoker
Understanding the effects of ERK hyperactivation in cancer: implications for therapy
Principal investigators: Lockwood, William W
Keywords: Cancer Biology; Cancer Signaling; Drug Development; Erk; Kinases; Lung Cancer; Mouse Models; Oncogenes; Phosphatases; Synthetic Lethality
Hypoxia promotes treatment-resistance and lineage transformation of EGFR-driven non-small cell lung cancer
Principal investigators: Shi, Rocky
Keywords: Cancer Physiology; Cell Signaling; Drug Resistance; Hypoxia; Lineage Transformation; Lung Cancer; Mouse Models Of Cancer; Tumour Microenvironment
The effects of smoking marijuana on lung cancer development: implications for screening and early detection.
Principal investigators: Lockwood, William W; Stirling, Peter C
Keywords: Cannabis; Carcinogenesis; Dna Damage; Early Detection; Lung Cancer; Marijuana; Mouse Models; Screening; Sequencing; Smoking
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Oncology
- Pediatrics
- Biomedical and Molecular Sciences
- Biochemistry
- Electrical and Computer Engineering
- Urologic Sciences
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Lynne-Marie Postovit
Oncology
2 shared papers, latest 2023
Lynne-Marie Postovit
Biomedical and Molecular Sciences
2 shared papers, latest 2023
Morag Park
Oncology
2 shared papers, latest 2023
Jonathan Spicer
Faculty
2 shared papers, latest 2023
Sidong Huang
Biochemistry
2 shared papers, latest 2023
Janusz Rak
Pediatrics
2 shared papers, latest 2023
Morag Park
Oncology
2 shared papers, latest 2023
Mads Daugaard
Urologic Sciences
1 shared papers, latest 2021
Wan Lam
Faculty
1 shared papers, latest 2007
Calum Macaulay
Electrical and Computer Engineering
1 shared papers, latest 2007
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