Faculty profile

Lynne-Marie Postovit

ResearcherBiomedical and Molecular SciencesQueen's University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Queen's University directory, so their courses may be missing. Find their university profile.

Lynne-Marie Postovit

Researcher

Biomedical and Molecular Sciences

Health Sciences

Queen's University

Kingston, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
17 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2025.
Supervised 1 trainee who won CIHR awards, most recently in 2021.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Breast Cancer Epigenetics Hypoxia Mrna Translation Crc Chromatin Clonal Evolution Dedifferentiation

Latest papers

Extracellular vesicles from aged individuals trigger mitochondrial dysfunction in hematopoietic progenitor cells.
Haematologica · 2026
Isolation of extracellular vesicles from minimal volume ascites fluid using strong anion exchange beads.
Nanoscale advances · 2026 · senior author
Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics.
eLife · 2026

All 27 publications

Latest funding

Epigenetic and Translational Coordination of Hypoxia-Induced Plasticity
CIHR · 2025 · Nominated PI
$1,009,800
Role of RIPK2 in Inflammatory Breast Cancer
CIHR · 2024 · Nominated PI
$65,000
Canada Research Chair - Tier 1
CIHR · 2023 · Nominated PI
$1,400,000

All 5 grants and awards

27 publications.

Extracellular vesicles from aged individuals trigger mitochondrial dysfunction in hematopoietic progenitor cells.

Grenier-Pleau IJ, Kaur J, Wells CJ, Vermeulen M, Slobodyanyuk M, Holmes SM, Bonneil É, Hall C, Beaulieu J, Hosseini M, Chan SM, Dick SA, Knapp DJHF, Tyryshkin K, Postovit LM, Thibault P, Rudan JF, Mann S, Craig AW, Reimand J, Chan EYW, Abraham SA

Haematologica2026

DOI: 10.3324/haematol.2025.288879 PMID: 41885030

Isolation of extracellular vesicles from minimal volume ascites fluid using strong anion exchange beads.

Cooper TT, Veliz L, Afzali F, Djoumessi C, Hovey OFJ, Myette RL, Johnston TPA, Wells C, Robertson T, Burger D, Abraham SA, Shepherd TG, Craig AW, Lagugné-Labarthet F, Lajoie GA, Postovit LM

Nanoscale advances2026Senior author

DOI: 10.1039/d6na00031b PMID: 42440870

Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics.

Papadopoli D, Palia R, Jovanovic P, Tabariès S, Ciccolini E, Sabourin V, Igelmann S, McLaughlan S, Zhan L, Kim H, Chekkal N, Szkop KJ, Bertomeu T, Zeng J, Vassalakis J, Afzali F, Mzoughi S, Guccione E, Tyers M, Avizonis D, Larsson O, Postovit LM, Djuranovic S, Ursini-Siegel J, Siegel PM, Pollak M, Topisirovic I

eLife2026

DOI: 10.7554/elife.106587 PMID: 42085321

Extracellular Vesicles Define Discrete Nano-Based Niches Within the Human Haematopoietic System.

Grenier-Pleau IJ, Wells CJ, Holmes SM, Hall C, Vermeulen M, de Villiers CA, Penders J, Pedersen SV, Dick SA, Bonneil E, Slobodyanyuk M, Nagree MS, Kaur J, McNaughton AJM, Beaulieu J, Stevens MM, Xie SZ, Rauh MJ, Postovit LM, Knapp DJHF, Reimand J, Tyryshkin K, Thibault P, Craig AW, Rudan JF, Mann S, Chan EYW, Abraham SA

Journal of extracellular vesicles2025

DOI: 10.1002/jev2.70181 PMID: 41307968

Epigenetic alterations facilitate transcriptional and translational programs in hypoxia.

Watt K, Dauber B, Szkop KJ, Lee L, Jovanovic P, Chen S, Palia R, Vassalakis JA, Cooper TT, Papadopoli D, Masvidal L, Jewer M, Tandoc K, Plummer H, Lajoie GA, Topisirovic I, Larsson O, Postovit LM

Nature cell biology2025Senior author

DOI: 10.1038/s41556-025-01786-8 PMID: 41102449

Emerging SERS and TERS MoS2 platforms for the characterization of plasma-derived extracellular vesicles.

Veliz L, Lambin C, Cooper TT, McCarvell WM, Lajoie GA, Postovit LM, Lagugné-Labarthet F

Nanoscale2025

DOI: 10.1039/d4nr04926h PMID: 40163166

Targeted proteomics of plasma extracellular vesicles uncovers MUC1 as combinatorial biomarker for the early detection of high-grade serous ovarian cancer.

Cooper TT, Dieters-Castator DZ, Liu J, Siegers GM, Pink D, Veliz L, Lewis JD, Lagugné-Labarthet F, Fu Y, Steed H, Lajoie GA, Postovit LM

Journal of ovarian research2024Senior author

DOI: 10.1186/s13048-024-01471-8 PMID: 39020428

Transcription factor ZIC2 regulates the tumorigenic phenotypes associated with both bulk and cancer stem cells in epithelial ovarian cancer.

Chen H, Lee LJ, Vincent KM, Xu Z, Liu J, Zhang G, Nakevska Z, Smith D, Lee CH, Postovit LM, Fu Y

Oncogene2024

DOI: 10.1038/s41388-024-03026-z PMID: 38594503

MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors.

Kim H, Lebeau B, Papadopoli D, Jovanovic P, Russo M, Avizonis D, Morita M, Afzali F, Ursini-Siegel J, Postovit LM, Witcher M, Topisirovic I

iScience2024

DOI: 10.1016/j.isci.2024.109188 PMID: 38433910

Cancer-associated Fibroblast-specific Expression of the Matricellular Protein CCN1 Coordinates Neovascularization and Stroma Deposition in Melanoma Metastasis.

Hutchenreuther J, Nguyen J, Quesnel K, Vincent KM, Petitjean L, Bourgeois S, Boyd M, Bou-Gharios G, Postovit LM, Leask A

Cancer research communications2024

DOI: 10.1158/2767-9764.crc-23-0571 PMID: 38363129

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Lynne-Marie Postovit

Research

Latest papers

Latest funding

Extracellular vesicles from aged individuals trigger mitochondrial dysfunction in hematopoietic progenitor cells.

Isolation of extracellular vesicles from minimal volume ascites fluid using strong anion exchange beads.

Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics.

Extracellular Vesicles Define Discrete Nano-Based Niches Within the Human Haematopoietic System.

Epigenetic alterations facilitate transcriptional and translational programs in hypoxia.

Emerging SERS and TERS MoS2 platforms for the characterization of plasma-derived extracellular vesicles.

Targeted proteomics of plasma extracellular vesicles uncovers MUC1 as combinatorial biomarker for the early detection of high-grade serous ovarian cancer.

Transcription factor ZIC2 regulates the tumorigenic phenotypes associated with both bulk and cancer stem cells in epithelial ovarian cancer.

MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors.

Cancer-associated Fibroblast-specific Expression of the Matricellular Protein CCN1 Coordinates Neovascularization and Stroma Deposition in Melanoma Metastasis.

Epigenetic and Translational Coordination of Hypoxia-Induced Plasticity

Role of RIPK2 in Inflammatory Breast Cancer

Canada Research Chair - Tier 1

A Proteomic Investigation to Determine the Clinical Potential and Biological Function of Extracellular Vesicles in Early Stage Epithelial Ovarian Cancer.

Dissecting and targeting SWI/SNF loss in de-differentiated endometrial carcinomas

Frequent collaborators

Lynne-Marie Postovit

Ivan Topisirovic

Kathrin Tyryshkin

Ivan Topisirovic

Morag Park

Jonathan Spicer

Morag Park

Janusz Rak

Sidong Huang

William Lockwood

Andrew Leask

Sonia Del Rincon

David Hess

Michael Pollak

Sonia Del Rincon

Michael Witcher

Richard Fahlman

Roseline Godbout

Andrew Leask

Antonis Koromilas

Dylan Burger

John Rudan

Vera Mazurak