Dean Fergusson, University of Manitoba

Research

Anticoagulation Critical Care Sepsis Blood Conservation Comparative Effectiveness Preoperative Medicine Tranexamic Acid Transfusion

Latest papers

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19
Journal of the American Medical Association (JAMA) · 2020
Recall of ICU Stay in Patients Managed With a Sedation Protocol or a Sedation Protocol With Daily Interruption
Critical Care Medicine · 2015
Early intravenous unfractionated heparin and mortality in septic shock.
Critical care medicine · 2008

All 3 publications

Latest funding

ANTI-THROMBOTIC THERAPY TO AMELIORATE COMPLICATIONS OF COVID-19 (ATTACC): A randomized, international, multi-centre, adaptive, controlled clinical trial
CIHR · 2020 · Co-investigator
$3,573,336
Integrating clinical data systems to improve the capacity, performance, and value of Manitoba's healthcare system
CIHR · 2019 · Co-investigator
$2,393,115
Tranexamic acid to reduce red blood cell transfusion in major non-cardiac surgery (TRACTION): A pragmatic, registry-based, pilot, randomized controlled trial
CIHR · 2018 · Principal investigator
$100,000

All 7 grants and awards

3 publications.

01

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19

Angus DC, Derde L, Al-Beidh F, Annane D, Arabi Y, Beane A, van Bentum-Puijk W, Berry L, Bhimani Z, Bonten M

Journal of the American Medical Association (JAMA)2020827 citations

DOI: 10.1001/jama.2020.17022

02

Recall of ICU Stay in Patients Managed With a Sedation Protocol or a Sedation Protocol With Daily Interruption

Burry L, Cook D, Herridge M, Devlin JW, Fergusson D, Meade M, Steinberg M, Skrobik Y, Olafson K, Burns K

Critical Care Medicine201544 citations

DOI: 10.1097/ccm.0000000000001196

03

Early intravenous unfractionated heparin and mortality in septic shock.

Zarychanski R, Doucette S, Fergusson D, Roberts D, Houston DS, Sharma S, Gulati H, Kumar A

Critical care medicine2008

DOI: 10.1097/ccm.0b013e31818b8c6b PMID: 18824906

ANTI-THROMBOTIC THERAPY TO AMELIORATE COMPLICATIONS OF COVID-19 (ATTACC): A randomized, international, multi-centre, adaptive, controlled clinical trial

Co-investigatorCIHR2020Operating Grant: COVID-19 Rapid Research Funding Opportunity - Therapeutics

Principal investigators: Zarychanski, Ryan; Escobedo, Jorge; Goligher, Ewan C; Lawler, Patrick R; Nicolau, Jose C

Keywords: Anti-Thrombotic; Bayesian Adaptive; Covid-19; Sepsis; Thrombosis

$3,573,336

Integrating clinical data systems to improve the capacity, performance, and value of Manitoba's healthcare system

Co-investigatorCIHR2019Team Grant - SPOR iCT Rewarding Success - Phase 3 - Manitoba

Principal investigators: Zarychanski, Ryan; Christodoulou, Christodoulous; Czaykowski, Piotr; Edwards, Jeanette M; Malazdrewicz, Deborah; Mozil, Kimberley A; Rigatto, Claudio; Tessier, Angela; Wright, Brock J; Komenda, Paul V; Pitz, Marshall

Keywords: Dialysis; Implementation-Effectiveness Trial; Innovative Clinical Trials; Nephrology; Oncology; Patient-Navigation; Registry-Based Randomized Trial; Stepped-Wedge Cluster Trial; Tranexamic Acid; Transfusion Medicine

$2,393,115

Tranexamic acid to reduce red blood cell transfusion in major non-cardiac surgery (TRACTION): A pragmatic, registry-based, pilot, randomized controlled trial

Principal investigatorCIHR2018Catalyst Grant: SPOR Innovative Clinical Trials (iCT)

Principal investigators: Zarychanski, Ryan; Callum, Jeannie L; HORSBURGH, MAC; Breau, Rodney H; Fergusson, Dean A; McIsaac, Daniel I; Mutter, Thomas C

Keywords: Blood Conservation; Comparative Effectiveness; Preoperative Medicine; Tranexamic Acid; Transfusion

$100,000

Heparin anticoagulation to improve outcomes in septic shock: The HALO International Phase II Trial

Principal investigatorCIHR2016Project Grant

Principal investigators: Zarychanski, Ryan; Fergusson, Dean A; Kumar, Anand

Keywords: Anticoagulation; Clinical Trials; Critical Care; Randomized Controlled Trials; Sepsis

$631,125

Heparin AnticoaguLation to improve Outcomes in septic shock: The HALO pilot

Principal investigatorCIHR2012Operating Grant

Principal investigators: Zarychanski, Ryan; Fergusson, Dean A

Keywords: Anticoagulation; Clinical Trial; Critical Care; Infection; Pilot Study; Randomized Controlled Trial; Sepsis

$288,152

A pilot randomized controlled trial to evaluate the efficacy of unfractionated Heparin in septic shock

Principal investigatorCIHR2011Operating Grant - PA: Regional Partnership Program : Manitoba

Principal investigators: Zarychanski, Ryan; Fergusson, Dean A

Keywords: Anticoagulants; Coagulation; Critical Care; Inflammation; Randomized Controlled Trials; Sepsis; Unfractionated Heparin

$100,000

Investigating the efficacy and safety of unfractionated Heparin in severe sepsis and septic shock

SupervisorCIHR2010Randomized Controlled Trials: Mentoring

Principal investigators: Zarychanski, Ryan

Keywords: Anticoagulants; Critical Care; Hematology; Randomized Control Trial; Sepsis; Unfractionated Heparin

$140,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Critical Care Medicine
Internal Medicine
Infectious Diseases/Internal Medicine
Medicine
General Internal Medicine
Anesthesia
Medicine/Neurology
Other

Applying for

Paper to mention

Subject: Prospective PhD student: Anticoagulation Dear Professor Fergusson, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19" (2020), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]