Faculty profile
Elissavet Kardami
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Research
Latest papers
Diastolic Dysfunction with Normal Ejection Fraction and Reduced Heart Rate in Mice Expressing Human Growth Hormone and Displaying Signs of Growth Hormone Insufficiency.
International journal of molecular sciences · 2024
Increased capacity to maintain glucose homeostasis in a transgenic mouse expressing human but not mouse growth hormone with developing high-fat diet-related insulin resistance, hepatic steatosis and adipose dysfunction.
Journal of molecular endocrinology · 2024
Effect of high fat diet on maternal behavior, brain-derived neurotrophic factor and neural stem cell proliferation in mice expressing human placental lactogen during pregnancy.
Journal of neuroendocrinology · 2024
Latest funding
- $646,363
The role of FGF2 isoforms in cardiac remodeling
CIHR · 2015 · Nominated PI
- $818,110
FGF2 Isoforms in Cardiac Hypertrophy
CIHR · 2009 · Nominated PI
- $1,950,000
CIHR IMPACT Strategic Training Program
CIHR · 2008 · Co-investigator
40 publications.
Diastolic Dysfunction with Normal Ejection Fraction and Reduced Heart Rate in Mice Expressing Human Growth Hormone and Displaying Signs of Growth Hormone Insufficiency.
Jin Y, Xiang B, Dolinsky VW, Kardami E, Cattini PA
Increased capacity to maintain glucose homeostasis in a transgenic mouse expressing human but not mouse growth hormone with developing high-fat diet-related insulin resistance, hepatic steatosis and adipose dysfunction.
Jin Y, Jarmasz JS, Sultana S, Cordero-Monroy L, Taylor CG, Zahradka P, Kardami E, Cattini PA
Effect of high fat diet on maternal behavior, brain-derived neurotrophic factor and neural stem cell proliferation in mice expressing human placental lactogen during pregnancy.
Moazzam S, Noorjahan N, Jin Y, Nagy JI, Kardami E, Cattini PA
A Cardiac Mitochondrial FGFR1 Mediates the Antithetical Effects of FGF2 Isoforms on Permeability Transition.
Srisakuldee W, Nickel BE, Fandrich RR, Zhang F, Pasumarthi KBS, Kardami E
Elimination of endogenous high molecular weight FGF2 prevents pressure-overload-induced systolic dysfunction, linked to increased FGFR1 activity and NR1D1 expression.
Koleini N, Nickel BE, Nagalingam RS, Landry NM, Fandrich RR, Cheung DYC, Dixon IM, Czubryt MP, Jassal DS, Cattini PA, Kardami E
SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation.
Landry NM, Rattan SG, Filomeno KL, Meier TW, Meier SC, Foran SJ, Meier CF, Koleini N, Fandrich RR, Kardami E, Duhamel TA, Dixon IMC
Simvastatin increases temozolomide-induced cell death by targeting the fusion of autophagosomes and lysosomes.
Shojaei S, Koleini N, Samiei E, Aghaei M, Cole LK, Alizadeh J, Islam MI, Vosoughi AR, Albokashy M, Butterfield Y, Marzban H, Xu F, Thliveris J, Kardami E, Hatch GM, Eftekharpour E, Akbari M, Hombach-Klonisch S, Klonisch T, Ghavami S
Low and High Molecular Weight FGF-2 Have Differential Effects on Astrocyte Proliferation, but Are Both Protective Against Aβ-Induced Cytotoxicity.
Chen X, Li Z, Cheng Y, Kardami E, Loh YP
Oxidized phospholipids in Doxorubicin-induced cardiotoxicity.
Koleini N, Nickel BE, Edel AL, Fandrich RR, Ravandi A, Kardami E
Elimination or neutralization of endogenous high-molecular-weight FGF2 mitigates doxorubicin-induced cardiotoxicity.
Koleini N, Santiago JJ, Nickel BE, Sequiera GL, Wang J, Fandrich RR, Jassal DS, Dhingra S, Kirshenbaum LA, Cattini PA, Kardami E
The role of FGF2 isoforms in cardiac remodeling
Principal investigators: Kardami, Elissavet
Keywords: Cardiac Hypertrophy; Cardiac Remodeling; Fibroblast Growth Factor 2 Isoforms; Fibroblasts; Neuropilin 1; Translational Application
FGF2 Isoforms in Cardiac Hypertrophy
Principal investigators: Kardami, Elissavet
Keywords: Cardiac Hypertrophy; Fibroblast-Myocyte Interaction; Fibrosis; Growth Factor Isoform; Signal Transduction; Transgenic Models
CIHR IMPACT Strategic Training Program
Principal investigators: Walley, Keith R
Keywords: Cardiovascular; Cell And Molecular Biology; Clinical Research; Clinician-Scientist; Environment; Gene; Genotyping; Imaging; Mentoring; Phenotyping; Physiology; Pulmonary; Teaching; Training; Transdisciplinary Thematic Research
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Human Anatomy & Cell Science
- Human Nutritional Sciences
- Mechanical Engineering
- Internal Medicine
- Physiology and Pathophysiology
- Other
Co-authors at University of Manitoba, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Thomas Klonisch
Human Anatomy & Cell Science
2 shared papers, latest 2020
Sabine Hombach-Klonisch
Faculty
2 shared papers, latest 2020
Sanjiv Dhingra
Physiology and Pathophysiology
1 shared papers, latest 2019
Mohsen Akbari
Mechanical Engineering
1 shared papers, latest 2020
Samer Mansour
Faculty
1 shared papers, latest 2017
Carla Taylor
Human Nutritional Sciences
1 shared papers, latest 2011
Ryan Zarychanski
Internal Medicine
1 shared papers, latest 2017
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