Faculty profile
Yassine El Hiani
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Dalhousie University directory, so their courses may be missing. Find their university profile.
Latest papers
TRPML1 loss disrupts lysosome-mitochondria homeostasis and sensitizes MDA-MB-231 triple-negative breast cancer cells to chemotherapy.
The Journal of biological chemistry · 2026 · senior author
Targeting TRPML3 inhibits proliferation and invasion, and enhances doxorubicin sensitivity by disrupting lysosomal acidification and mitochondrial function in triple-negative breast cancer.
Biochimica et biophysica acta. Molecular cell research · 2025 · senior author
TRPML3/BK complex promotes autophagy and bacterial clearance by providing a positive feedback regulation of mTOR via PI3P.
Proceedings of the National Academy of Sciences of the United States of America · 2023
Latest funding
- $217,000
FUNCTIONAL CHARACTERIZATION OF THE SLC26A9 ION CHANNEL PERMEATION PATHWAY
NSERC · 2018 · Principal investigator
- $12,500
FUNCTIONAL CHARACTERIZATION OF THE SLC26A9 ION CHANNEL PERMEATION PATHWAY
NSERC · 2018 · Principal investigator
39 publications.
TRPML1 loss disrupts lysosome-mitochondria homeostasis and sensitizes MDA-MB-231 triple-negative breast cancer cells to chemotherapy.
Syeda AK, Almasi S, Benson CJ, Kennedy BE, Yoast RM, Emrich SM, Delima-Baril A, Slade L, Pakkiriswami S, Vijayan VV, Sheela UB, Gujar S, Pulinilkunnil T, Trebak M, El Hiani Y
Targeting TRPML3 inhibits proliferation and invasion, and enhances doxorubicin sensitivity by disrupting lysosomal acidification and mitochondrial function in triple-negative breast cancer.
Gomes GMA, Xu M, Syeda AKR, Raudonis R, Almasi S, Vijayan VV, Gujar S, Dong X, Cheng Z, Pulinilkunnil T, El Hiani Y
TRPML3/BK complex promotes autophagy and bacterial clearance by providing a positive feedback regulation of mTOR via PI3P.
Xu M, Zhong XZ, Huang P, Jaślan D, Wang P, Sun X, Weiden EM, El Hiani Y, Grimm C, Dong XP
TRPM2: bridging calcium and ROS signaling pathways-implications for human diseases.
Maliougina M, El Hiani Y
Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity.
Biswas D, Slade L, Duffley L, Mueller N, Dao KT, Mercer A, Pakkiriswami S, El Hiani Y, Kienesberger PC, Pulinilkunnil T
Two positively charged amino acid side-chains in the inner vestibule of the CFTR channel pore play analogous roles in controlling anion binding and anion conductance.
Linsdell P, Irving CL, Cowley EA, El Hiani Y
TRPML1-Emerging Roles in Cancer.
Yang Y, Zhai X, El Hiani Y
Getting Lost in the Cell-Lysosomal Entrapment of Chemotherapeutics.
Zhai X, El Hiani Y
Branched-chain ketoacid overload inhibits insulin action in the muscle.
Biswas D, Dao KT, Mercer A, Cowie AM, Duffley L, El Hiani Y, Kienesberger PC, Pulinilkunnil T
Exploring the Therapeutic Potential of Membrane Transport Proteins: Focus on Cancer and Chemoresistance.
Almasi S, El Hiani Y
FUNCTIONAL CHARACTERIZATION OF THE SLC26A9 ION CHANNEL PERMEATION PATHWAY
Principal investigators: El Hiani, Yassine
Keywords: Gating; Ion channels; Permeation; Pore; SLC26A9; Structure; Transporters
FUNCTIONAL CHARACTERIZATION OF THE SLC26A9 ION CHANNEL PERMEATION PATHWAY
Principal investigators: ElHiani, Yassine
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Paul Linsdell and Yassine El Hiani: 15 shared papers
- Paola Marcato and Shashi Gujar: 11 shared papers
- Shashi Gujar and Yassine El Hiani: 6 shared papers
- THOMAS PULINILKUNNIL and Yassine El Hiani: 5 shared papers
- Shashi Gujar and THOMAS PULINILKUNNIL: 3 shared papers
- Paola Marcato and Yassine El Hiani: 1 shared paper
- Xianping Dong and Zhenyu Cheng: 1 shared paper
- Xianping Dong and Shashi Gujar: 1 shared paper
- Xianping Dong and THOMAS PULINILKUNNIL: 1 shared paper
- Xianping Dong and Yassine El Hiani: 1 shared paper
- Jun Wang and Zhenyu Cheng: 1 shared paper
- Jun Wang and Shashi Gujar: 1 shared paper
- Jun Wang and Yassine El Hiani: 1 shared paper
- Zhenyu Cheng and Shashi Gujar: 1 shared paper
- Zhenyu Cheng and Yassine El Hiani: 1 shared paper
- Physiology and Biophysics
- Pathology
- Microbiology and Immunology
- Physiology & Biophysics
- Biochemistry and Molecular Biology
Co-authors at Dalhousie University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Paul Linsdell
Physiology & Biophysics
15 shared papers, latest 2021
Shashi Gujar
Pathology
6 shared papers, latest 2026
THOMAS PULINILKUNNIL
Biochemistry and Molecular Biology
5 shared papers, latest 2026
Zhenyu Cheng
Microbiology and Immunology
1 shared papers, latest 2025
Jun Wang
Microbiology and Immunology
1 shared papers, latest 2019
Xianping Dong
Physiology and Biophysics
1 shared papers, latest 2025
Paola Marcato
Pathology
1 shared papers, latest 2019
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