Luke Jeffrey Janssen

Research

Research areas, by share of publications

Asthma and respiratory diseasesMedicine
Ion channel regulation and functionBiochemistry, Genetics and Molecular Biology
Ion Channels and ReceptorsNeuroscience
Respiratory and Cough-Related ResearchMedicine
Nitric Oxide and Endothelin EffectsMedicine

Research areas are derived from OpenAlex topics of their publications.

Latest papers

The Blind Scientist: Unmasking the Misguided Methodology of Neo-Darwinism
2025
Differential Cellular Sensing of Fusion from within and Fusion from without during Virus Infection
Viruses · 2023
Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance
Nature Communications · 2022

All 203 publications

Latest funding

Intracellular calcium spikes trigger cytoskeletal reorganization, adhesion and migration
NSERC · 2014 · Principal investigator
$235,000
Calcium-signalling and gene expression in human fibroblasts
CIHR · 2014 · Nominated PI
$694,795
Elucidating the role of calcium-waves in human eosinophil migration and degranulation
CIHR · 2013 · Supervisor
$17,500

All 5 grants and awards

Researchers with similar interests

Peter Helli

Nursing

Ion channel regulation and function, Ion Channels and Receptors

Clive Davis

Medicine

Asthma and respiratory diseases, Ion channel regulation and function

Parameswaran Krishna Nair

Medicine

Asthma and respiratory diseases, Respiratory and Cough-Related Research

Imran Satia

Medicine

Asthma and respiratory diseases, Respiratory and Cough-Related Research

Paul O'Byrne

Medicine

Asthma and respiratory diseases, Respiratory and Cough-Related Research

Terence Ho

Medicine

Asthma and respiratory diseases, Respiratory and Cough-Related Research

From the 150 most recent of 203 publications.

01

The Blind Scientist: Unmasking the Misguided Methodology of Neo-Darwinism

Bonitto AJ, Knox JS

2025

DOI: 10.56315/pscf3-25bonitto

02

Differential Cellular Sensing of Fusion from within and Fusion from without during Virus Infection

Hare DN, Murdza T, Collins S, Schulz K, Mukherjee S, de Antueno R, Janssen L, Duncan R, Mossman KL

Viruses20234 citations

DOI: 10.3390/v15020301

03

Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Lebeau PF, Byun JH, Platko K, Saliba P, Sguazzin M, MacDonald ME, Paré G, Steinberg GR, Janssen LJ, Igdoura SA

Nature Communications2022107 citationsOpen Access

DOI: 10.1038/s41467-022-28240-9 PMID: W4210840666

04

Topical therapy with negative allosteric modulators of the calcium-sensing receptor (calcilytics) for the management of asthma: the beginning of a new era?

Riccardi D, Ward JPT, Yarova PL, Janssen LJ, Lee TH, Ying S, Corrigan CJ

European Respiratory Journal202216 citationsOpen Access

DOI: 10.1183/13993003.02103-2021 PMID: W4205253173

05

WHY SCIENCE AND FAITH BELONG TOGETHER: Stories of Mutual Enrichment

Janssen L

2022First author

06

SCIENCE AND THE CHRISTIAN FAITH: A Guide for the Perplexed

Janssen L

2022First author

07

The Cycling of Intracellular Calcium Released in Response to Fluid Shear Stress Is Critical for Migration-Associated Actin Reorganization in Eosinophils

Son K, Hussain A, Sehmi R, Janssen L

Cells202112 citationsSenior author

DOI: 10.3390/cells10010157

08

Pandemics in Need of a Christian Response

Janssen LJ

20213 citationsFirst author

09

Are Global Disasters the Result of Original Sin or Part of Our Training as Co-regents?

Janssen LJ

20211 citationsFirst author

10

The eosinophil actin cytoskeleton undergoes rapid rearrangement in response to fluid shear stress

Son K, Small M, Sehmi R, Janssen L

Journal of Leukocyte Biology20207 citationsSenior author

DOI: 10.1002/jlb.1ma0320-349rr

Intracellular calcium spikes trigger cytoskeletal reorganization, adhesion and migration

Principal investigatorNSERC2014Discovery Grants Program - Individual

Principal investigators: Janssen, Luke

$235,000

Calcium-signalling and gene expression in human fibroblasts

Nominated PICIHR2014Operating Grant

Principal investigators: Janssen, Luke J

Keywords: Calcium; Fibroblasts; Fibrosis; Gene Expression; Ion Channels

$694,795

Elucidating the role of calcium-waves in human eosinophil migration and degranulation

SupervisorCIHR2013Master's Award: Canada Graduate Scholarships

Principal investigators: Ahmadzai, Mohammad M

Keywords: Allergies; Asthma; Calcium Signaling; Calcium Waves; Confocal Microscopy; Degranulation; Eosinophil; Migration

$17,500

Isoprostane-mediated regulation of airway and vascular smooth muscles

Nominated PICIHR2008Operating Grant

Principal investigators: Janssen, Luke J

Keywords: Contraction; Isoprostanes; Patch-Clamp Electrophysiology; Prostanoids; Smooth Muscle

$100,000

Arterial thermoplasty in coronary artery bypass surgery

Nominated PICIHR2008Operating Grant

Principal investigators: Janssen, Luke J

Keywords: Coronary Artery By-Pass Surgery; Human Radial Artery; Myocardial Infarction; Thermal Injury; Vasospasm

$309,483

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Courses taught

5

Methods in Pharmacology
PHARMAC 3B06B · last taught 2026
Undergraduate
Introduction to Pharmacology
PHARMAC 3A06A · last taught 2025
Undergraduate
Methods in Pharmacology
PHARMAC 3B06A · last taught 2025
Undergraduate
Senior Thesis
PHARMAC 4T15 · last taught 2022
Undergraduate
Receptor-Drug Interactions
PHARMAC 4A03 · last taught 2017
Undergraduate

Frequent collaborators

Medicine
Surgery
Nursing
Anesthesia
Pathology & Molecular Medicine
Psychiatry & Behavioural Neurosciences
Obstetrics & Gynecology

Co-authors at McMaster University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Tariq Aziz

Pathology & Molecular Medicine

3 shared papers, latest 2011

Wolfgang Kunze

Psychiatry & Behavioural Neurosciences

2 shared papers, latest 2015

Jane Foster

Psychiatry & Behavioural Neurosciences

1 shared papers, latest 2010

Martin R Stampfli

Pathology & Molecular Medicine

1 shared papers, latest 2007

Richard C Austin

Medicine

1 shared papers, latest 2022

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mention

Subject: Prospective PhD student: Asthma and respiratory diseases Dear Professor Janssen, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "The Blind Scientist: Unmasking the Misguided Methodology of Neo-Darwinism" (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Open in email

Luke Jeffrey Janssen

Research

Latest papers

Latest funding

Researchers with similar interests

Peter Helli

Clive Davis

Parameswaran Krishna Nair

Imran Satia

Paul O'Byrne

Terence Ho

The Blind Scientist: Unmasking the Misguided Methodology of Neo-Darwinism

Differential Cellular Sensing of Fusion from within and Fusion from without during Virus Infection

Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Topical therapy with negative allosteric modulators of the calcium-sensing receptor (calcilytics) for the management of asthma: the beginning of a new era?

WHY SCIENCE AND FAITH BELONG TOGETHER: Stories of Mutual Enrichment

SCIENCE AND THE CHRISTIAN FAITH: A Guide for the Perplexed

The Cycling of Intracellular Calcium Released in Response to Fluid Shear Stress Is Critical for Migration-Associated Actin Reorganization in Eosinophils

Pandemics in Need of a Christian Response

Are Global Disasters the Result of Original Sin or Part of Our Training as Co-regents?

The eosinophil actin cytoskeleton undergoes rapid rearrangement in response to fluid shear stress

Intracellular calcium spikes trigger cytoskeletal reorganization, adhesion and migration

Calcium-signalling and gene expression in human fibroblasts

Elucidating the role of calcium-waves in human eosinophil migration and degranulation

Isoprostane-mediated regulation of airway and vascular smooth muscles

Arterial thermoplasty in coronary artery bypass surgery

Courses taught

Frequent collaborators

Martin Rainer Kolb

Paul O'Byrne

Peter Helli

Parameswaran Krishna Nair

Jeremy Hernandez

Roma Sehmi

Kjetil Ask

Mark David Inman

Gail Gauvreau

Gerard Cox

Robert M K W Lee

Kieran Killian

Tariq Aziz

Mark Larche

Wolfgang Kunze

Chiu-yin Kwan

Karen Mossman

Nader Khalidi

Manali Mukherjee

Jane Foster

Ian Rodger

Margaret Larche

Martin R Stampfli

Joan Krepinsky

Carl Richards

Kevin Teoh

Richard C Austin