Thien-Fah Mah, University of Ottawa

Research

Read how they describe their research on their University of Ottawa profile.

Latest papers

Polyphosphate kinase regulates LPS structure and polymyxin resistance during starvation in E. coli.
PLoS biology · 2024
Anaerobic fluorescent reporters for live imaging of Pseudomonas aeruginosa.
Frontiers in microbiology · 2023
Establishment of a Novel Rat Model of Gram-Negative Periprosthetic Joint Infection Using Cementless Hip Hemiarthroplasty.
The Journal of bone and joint surgery. American volume · 2023

All 30 publications

Latest funding

An anaerobic chamber to study the behaviour of microbes.
NSERC · 2020 · Co-investigator
$39,776
NSERC CREATE in Technologies for Microbiome Science and Engineering (TECHNOMISE)
NSERC · 2017 · Co-investigator
$1,650,000
Multilayer Hybrid Biomaterial for Treatment of Diabetic Foot Ulcers
CIHR · 2016 · Co-investigator
$367,200

All 8 grants and awards

30 publications.

01

Polyphosphate kinase regulates LPS structure and polymyxin resistance during starvation in E. coli.

Baijal K, Abramchuk I, Herrera CM, Mah TF, Trent MS, Lavallée-Adam M, Downey M

PLoS biology2024

DOI: 10.1371/journal.pbio.3002558 PMID: 38478588

02

Anaerobic fluorescent reporters for live imaging of Pseudomonas aeruginosa.

Tchagang CF, Mah TF, Campbell-Valois FX

Frontiers in microbiology2023

DOI: 10.3389/fmicb.2023.1245755 PMID: 37928662

03

Establishment of a Novel Rat Model of Gram-Negative Periprosthetic Joint Infection Using Cementless Hip Hemiarthroplasty.

Ibrahim MM, Liu Y, Ure K, Hall CW, Mah TF, Abdelbary H

The Journal of bone and joint surgery. American volume2023

DOI: 10.2106/jbjs.22.00094 PMID: 36598474

04

RpoN-Based stapled peptides with improved DNA binding suppress Pseudomonas aeruginosa virulence.

Paquette AR, Payne SR, McKay GA, Brazeau-Henrie JT, Darnowski MG, Kammili A, Bernal F, Mah TF, Gruenheid S, Nguyen D, Boddy CN

RSC medicinal chemistry2022

DOI: 10.1039/d1md00371b PMID: 35647551

05

Giving antibiotics an assist.

Mah TF

Science (New York, N.Y.)2021First author

DOI: 10.1126/science.abj3062 PMID: 34112683

06

Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models.

Guzmán-Soto I, McTiernan C, Gonzalez-Gomez M, Ross A, Gupta K, Suuronen EJ, Mah TF, Griffith M, Alarcon EI

iScience2021

DOI: 10.1016/j.isci.2021.102443 PMID: 34013169

07

Nanoengineering the surface of corneal implants: towards functional anti-microbial and biofilm materials.

Khatoon Z, Guzmán-Soto I, McTiernan CD, Lazurko C, Simpson F, Zhang L, Cortes D, Mah TF, Griffith M, Alarcon EI

RSC advances2020

DOI: 10.1039/d0ra03659e PMID: 35517329

08

Multifunctional Nano and Collagen-Based Therapeutic Materials for Skin Repair.

Lazurko C, Khatoon Z, Goel K, Sedlakova V, Eren Cimenci C, Ahumada M, Zhang L, Mah TF, Franco W, Suuronen EJ, Alarcon EI

ACS biomaterials science & engineering2020

DOI: 10.1021/acsbiomaterials.9b01281 PMID: 33464871

09

Potentiation of Aminoglycoside Lethality by C4-Dicarboxylates Requires RpoN in Antibiotic-Tolerant Pseudomonas aeruginosa.

Hall CW, Farkas E, Zhang L, Mah TF

Antimicrobial agents and chemotherapy2019Senior author

DOI: 10.1128/aac.01313-19 PMID: 31383655

10

Loss of the Two-Component System TctD-TctE in Pseudomonas aeruginosa Affects Biofilm Formation and Aminoglycoside Susceptibility in Response to Citric Acid.

Taylor PK, Zhang L, Mah TF

mSphere2019Senior author

DOI: 10.1128/msphere.00102-19 PMID: 30842268

An anaerobic chamber to study the behaviour of microbes.

Co-investigatorNSERC2020Research Tools and Instruments

Principal investigators: CampbellValois, FrançoisXavier

$39,776

NSERC CREATE in Technologies for Microbiome Science and Engineering (TECHNOMISE)

Co-investigatorNSERC2017Collaborative Research and Training Experience

Principal investigators: Figeys, Daniel

$1,650,000

Multilayer Hybrid Biomaterial for Treatment of Diabetic Foot Ulcers

Co-investigatorCIHR2016Project Grant

Principal investigators: Alarcón, Emilio I; Suuronen, Erik

Keywords: Collagen Hydrogel; Diabetic Foot Ulcers; Infection; Nanosilver; Tissue Engineering; Wound Healing

$367,200

Mechanisms of Survival of Pseudomonas aeruginosa Biofilms in the Environment

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Mah, ThienFah

$186,000

Anti-microbial scaffold materials for cutaneous wound healing

Co-investigatorNSERC2012Collaborative Health Research Projects

Principal investigators: Harden, James

$143,623

Anti-microbial scaffold materials for cutaneous wound healing

Co-investigatorCIHR2011Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Harden, James L

Keywords: Anti-Microbial Materials; Biomaterials; Hydrogels; Nanoparticles; Protein Engineering; Regenerative Medicine; Tissue Engineering; Wound Healing

$273,128

Basic mechanisms of survival of pseudomonas aeruginosa biofilms in the environment

Principal investigatorNSERC2010Discovery Grants Program - Individual

Principal investigators: Mah, ThienFah

$135,000

Basic mechanisms of survival of biofilms in the environment

Principal investigatorNSERC2008Discovery Grants Program - Individual

Principal investigators: Mah, ThienFah

$40,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biochemistry, Microbiology and Immunology
Cellular and Molecular Medicine
Department of Medicine
Biology
Pediatrics
Medicine
Orthopedic Surgery
Other

Co-authors at University of Ottawa, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Antonio Colavita

Cellular and Molecular Medicine

2 shared papers, latest 2017

Subash Sad

Biochemistry, Microbiology and Immunology

1 shared papers, latest 2016

Samantha Gruenheid

Microbiology and Immunology

1 shared papers, latest 2022

Michael Downey

Cellular and Molecular Medicine

1 shared papers, latest 2024

May Griffith

Pharmacologie - Physiologie

1 shared papers, latest 2020

Hesham Abdelbary

Orthopedic Surgery

1 shared papers, latest 2023

Raphael Saginur

Department of Medicine

1 shared papers, latest 2009

Robert Slinger

Department of Medicine

1 shared papers, latest 2015

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mention

Subject: Prospective PhD student Dear Professor Mah, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Polyphosphate kinase regulates LPS structure and polymyxin resistance during starvation in E. coli." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Thien-Fah Mah

Research

Latest papers

Latest funding

Polyphosphate kinase regulates LPS structure and polymyxin resistance during starvation in E. coli.

Anaerobic fluorescent reporters for live imaging of Pseudomonas aeruginosa.

Establishment of a Novel Rat Model of Gram-Negative Periprosthetic Joint Infection Using Cementless Hip Hemiarthroplasty.

RpoN-Based stapled peptides with improved DNA binding suppress Pseudomonas aeruginosa virulence.

Giving antibiotics an assist.

Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models.

Nanoengineering the surface of corneal implants: towards functional anti-microbial and biofilm materials.

Multifunctional Nano and Collagen-Based Therapeutic Materials for Skin Repair.

Potentiation of Aminoglycoside Lethality by C4-Dicarboxylates Requires RpoN in Antibiotic-Tolerant Pseudomonas aeruginosa.

Loss of the Two-Component System TctD-TctE in Pseudomonas aeruginosa Affects Biofilm Formation and Aminoglycoside Susceptibility in Response to Citric Acid.

An anaerobic chamber to study the behaviour of microbes.

NSERC CREATE in Technologies for Microbiome Science and Engineering (TECHNOMISE)

Multilayer Hybrid Biomaterial for Treatment of Diabetic Foot Ulcers

Mechanisms of Survival of Pseudomonas aeruginosa Biofilms in the Environment

Anti-microbial scaffold materials for cutaneous wound healing

Anti-microbial scaffold materials for cutaneous wound healing

Basic mechanisms of survival of pseudomonas aeruginosa biofilms in the environment

Basic mechanisms of survival of biofilms in the environment

Frequent collaborators

Antonio Colavita

Subash Sad

Samantha Gruenheid

Alex Wong

Michael Downey

Dao Nguyen

May Griffith

Hesham Abdelbary

Alex Wong

May Griffith

Raphael Saginur

Robert Slinger

Thien-Fah Mah

Research

Latest papers

Latest funding

Polyphosphate kinase regulates LPS structure and polymyxin resistance during starvation in E. coli.

Anaerobic fluorescent reporters for live imaging of Pseudomonas aeruginosa.

Establishment of a Novel Rat Model of Gram-Negative Periprosthetic Joint Infection Using Cementless Hip Hemiarthroplasty.

RpoN-Based stapled peptides with improved DNA binding suppress Pseudomonas aeruginosa virulence.

Giving antibiotics an assist.

Mimicking biofilm formation and development: Recent progress in in&#xa0;vitro and in&#xa0;vivo biofilm models.

Nanoengineering the surface of corneal implants: towards functional anti-microbial and biofilm materials.

Multifunctional Nano and Collagen-Based Therapeutic Materials for Skin Repair.

Potentiation of Aminoglycoside Lethality by C4-Dicarboxylates Requires RpoN in Antibiotic-Tolerant Pseudomonas aeruginosa.

Loss of the Two-Component System TctD-TctE in Pseudomonas aeruginosa Affects Biofilm Formation and Aminoglycoside Susceptibility in Response to Citric Acid.

An anaerobic chamber to study the behaviour of microbes.

NSERC CREATE in Technologies for Microbiome Science and Engineering (TECHNOMISE)

Multilayer Hybrid Biomaterial for Treatment of Diabetic Foot Ulcers

Mechanisms of Survival of Pseudomonas aeruginosa Biofilms in the Environment

Anti-microbial scaffold materials for cutaneous wound healing

Anti-microbial scaffold materials for cutaneous wound healing

Basic mechanisms of survival of pseudomonas aeruginosa biofilms in the environment

Basic mechanisms of survival of biofilms in the environment

Frequent collaborators

Antonio Colavita

Subash Sad

Samantha Gruenheid

Alex Wong

Michael Downey

Dao Nguyen

May Griffith

Hesham Abdelbary

Alex Wong

May Griffith

Raphael Saginur

Robert Slinger

Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models.