Faculty profile

Anthony Gramolini

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ProfessorDepartment of PhysiologyUniversity of Toronto

Anthony Gramolini

Professor

Department of Physiology

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

ORCID

Supervision signals

Professors usually supervise graduate students in their department's programs.
1 publication in the last five years, latest in 2026.
Principal investigator on 10 research grants (9 CIHR, 1 NSERC), most recently in 2023.
Supervised 4 trainees who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

237

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Endoplasmic Reticulum Mass Spectrometry Heart Disease Cardiomyocyte Myopathy Organellar Development Cell Communication Intercalated Disk

Latest papers

Evaluating the temporal and sociodemographic generalizability of the emergency heart failure mortality risk grade.
ESC heart failure · 2026
An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy.
Journal of molecular and cellular cardiology · 2021
Machine learning vs. conventional statistical models for predicting heart failure readmission and mortality.
ESC heart failure · 2021

All 15 publications

Latest funding

Scaled biomanufacturing of mature stem cell-derived cardiomyocytes via electrical stimulation
CIHR · 2026 · Co-investigator
$990,676
Multiomic approaches to identify at-risk patients with thoracic aortic aneurysms
CIHR · 2025 · Supervisor
$120,000
Mechanisms of aT-catenin phosphoregulation at the intercalated disc and its impact on the function of healthy and diseased hearts
CIHR · 2024 · Supervisor
$120,000

All 22 grants and awards

15 publications.

Evaluating the temporal and sociodemographic generalizability of the emergency heart failure mortality risk grade.

Abdul-Samad K, Wang X, Austin PC, Abdel-Qadir H, McIntosh C, Gramolini A, Mamdani M, Epelman S, Ross HJ, Lee DS

ESC heart failure2026

DOI: 10.1093/eschf/xvag156 PMID: 42212505

An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy.

Wang EY, Kuzmanov U, Smith JB, Dou W, Rafatian N, Lai BFL, Lu RXZ, Wu Q, Yazbeck J, Zhang XO, Sun Y, Gramolini A, Radisic M

Journal of molecular and cellular cardiology2021

DOI: 10.1016/j.yjmcc.2021.06.012 PMID: 34216608

Machine learning vs. conventional statistical models for predicting heart failure readmission and mortality.

Shin S, Austin PC, Ross HJ, Abdel-Qadir H, Freitas C, Tomlinson G, Chicco D, Mahendiran M, Lawler PR, Billia F, Gramolini A, Epelman S, Wang B, Lee DS

ESC heart failure2021

DOI: 10.1002/ehf2.13073 PMID: 33205591

Machine Learning Compared With Conventional Statistical Models for Predicting Myocardial Infarction Readmission and Mortality: A Systematic Review

Cho SM, Austin PC, Ross HJ, Abdel-Qadir H, Chicco D, Tomlinson G, Taheri C, Foroutan F, Lawler PR, Billia F

Canadian Journal of Cardiology202161 citations

DOI: 10.1016/j.cjca.2021.02.020

Mapping signalling perturbations in myocardial fibrosis via the integrative phosphoproteomic profiling of tissue from diverse sources.

Kuzmanov U, Wang EY, Vanderlaan R, Kim DH, Lee SH, Hadipour-Lakmehsari S, Guo H, Zhao Y, McFadden M, Sharma P, Billia F, Radisic M, Gramolini A, Emili A

Nature biomedical engineering2020

DOI: 10.1038/s41551-020-0585-y PMID: 32661320

Identifying Low-Abundance Biomarkers: Aptamer-Based Proteomics Potentially Enables More Sensitive Detection in Cardiovascular Diseases.

Gramolini A, Lau E, Liu PP

Circulation2016First author

DOI: 10.1161/circulationaha.116.022940 PMID: 27444931

Whole Genome Sequence of Multiple Myeloma-Prone C57BL/KaLwRij Mouse Strain Suggests the Origin of Disease Involves Multiple Cell Types.

Amend SR, Wilson WC, Chu L, Lu L, Liu P, Serie D, Su X, Xu Y, Wang D, Gramolini A, Wen XY, O'Neal J, Hurchla M, Vachon CM, Colditz G, Vij R, Weilbaecher KN, Tomasson MH

PloS one2015

DOI: 10.1371/journal.pone.0127828 PMID: 26020268

Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms.

Spillane DR, Wang DY, Newbigging S, Wang Y, Shi CX, Cho HR, Shimizu H, Gramolini A, Liu M, Wen XY

PloS one2015

DOI: 10.1371/journal.pone.0135755 PMID: 26291700

Targeted protein identification, quantification and reporting for high-resolution nanoflow targeted peptide monitoring.

Hewel JA, Phanse S, Liu J, Bousette N, Gramolini A, Emili A

Journal of proteomics2013

DOI: 10.1016/j.jprot.2012.10.020 PMID: 23124093

Cathepsin‐L Ameliorates Cardiac Hypertrophy Through Activation of the Autophagy–Lysosomal Dependent Protein Processing Pathways

Journal of the American Heart Association2013113 citationsOpen Access

DOI: 10.1161/jaha.113.000191 PMID: W2043262554

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2023

Subject: Prospective PhD student: Endoplasmic Reticulum Dear Professor Gramolini, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Evaluating the temporal and sociodemographic generalizability of the emergency heart failure mortality risk grade." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "The role of reticulon homology domain (RHD) protein and related family members in the sarco(endo)plasmic formation and regulation in the cardiac myocyte" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Anthony Gramolini

Research

Latest papers

Latest funding

Evaluating the temporal and sociodemographic generalizability of the emergency heart failure mortality risk grade.

An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy.

Machine learning vs. conventional statistical models for predicting heart failure readmission and mortality.

Machine Learning Compared With Conventional Statistical Models for Predicting Myocardial Infarction Readmission and Mortality: A Systematic Review

Mapping signalling perturbations in myocardial fibrosis via the integrative phosphoproteomic profiling of tissue from diverse sources.

Identifying Low-Abundance Biomarkers: Aptamer-Based Proteomics Potentially Enables More Sensitive Detection in Cardiovascular Diseases.

Whole Genome Sequence of Multiple Myeloma-Prone C57BL/KaLwRij Mouse Strain Suggests the Origin of Disease Involves Multiple Cell Types.

Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms.

Targeted protein identification, quantification and reporting for high-resolution nanoflow targeted peptide monitoring.

Cathepsin‐L Ameliorates Cardiac Hypertrophy Through Activation of the Autophagy–Lysosomal Dependent Protein Processing Pathways

Scaled biomanufacturing of mature stem cell-derived cardiomyocytes via electrical stimulation

Multiomic approaches to identify at-risk patients with thoracic aortic aneurysms

Mechanisms of aT-catenin phosphoregulation at the intercalated disc and its impact on the function of healthy and diseased hearts

The role of reticulon homology domain (RHD) protein and related family members in the sarco(endo)plasmic formation and regulation in the cardiac myocyte

Characterizing the Role of VAPB as a Novel Regulator of Cardiac Structure and Function

Dissecting the role of hemodynamics in ascending aorta aneurysm development

Molecular Analyses of the Intercalated Disc Protein Tmem65 as a Novel Regulator of Cardiac Communication

Multi-colour super-resolution microscopy for mechanotransduction studies at the single molecule level

Particle size analysing system for material composites applications in the biomedical engineering field

Detailed characterisation of the role of Reep5 in endo(sarco)plasmic formation, maintenance, and function in cardiac muscle

Frequent collaborators

Andrew Emili

Slava Epelman

Filio Billia

Milica Radisic

George Tomlinson

Xiao-Yan Wen

BO WANG

Peter Liu

Muhammad Mamdani

Yu Sun

Mingyao Liu

Chris McIntosh

Farid Foroutan

Gordon Keller