Faculty profile
Brian Cuthbertson
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Read how they describe their research on their University of Toronto profile.
Latest papers
Establishing core outcomes and minimal clinically important differences for childhood steroid sensitive nephrotic syndrome clinical trials: results from a Delphi consensus process.
Pediatric nephrology (Berlin, Germany) · 2026
Sedating with volatile anaesthetics for COVID-19 and non-COVID-19 acute hypoxaemic respiratory failure patients in ICU (SAVE-ICU): protocol for a randomised clinical trial.
BMJ open · 2025 · senior author
Using Bayesian pre-trial simulations to optimize the design of adaptive clinical trials in childhood nephrotic syndrome.
Contemporary clinical trials · 2025
Latest funding
- $730,576
The PLATform for INnovative Multicentre trials for comorbid chronic Pain and Depressive disorders (PLATINuM-PD)
CIHR · 2026 · Co-investigator
- $25,000
From Best Evidence to Best Practice: Advancing ICU Sedation Through SAVE-ICU Knowledge Translation
CIHR · 2025 · Co-investigator
- $883,029
The Randomized Embedded Multifactorial Adaptive Platform Trial in Community-Acquired Pneumonia (REMAP-CAP): Enshrining a Global Pandemic Research Response to COVID-19 and Beyond
CIHR · 2022 · Co-investigator
15 publications.
Establishing core outcomes and minimal clinically important differences for childhood steroid sensitive nephrotic syndrome clinical trials: results from a Delphi consensus process.
Robinson CH, Carter S, Aman N, Bruno V, Chan S, Cuthbertson B, Garner M, Fan E, Licht C, McKay AM, Radhakrishnan S, Rowley V, Teoh CW, Vasilevska-Ristovska JZ, Heath A, Parekh RS
Sedating with volatile anaesthetics for COVID-19 and non-COVID-19 acute hypoxaemic respiratory failure patients in ICU (SAVE-ICU): protocol for a randomised clinical trial.
Jerath A, Slessarev M, Martin C, D'Aragon F, Carrier FM, Senaratne J, Meggison H, Hooper J, Alexandros Cavayas Y, Goligher EC, Couture EJ, Randall I, Hatzakorzian R, Jacka M, Wiener-Kronish J, Xie Z, Pinto RL, Cuthbertson B, SAVE-ICU Investigators and the Canadian Critical Care Trials Group
Using Bayesian pre-trial simulations to optimize the design of adaptive clinical trials in childhood nephrotic syndrome.
Robinson CH, Parekh RS, Cuthbertson B, Fan E, Ouyang Y, Heath A
High-flow nasal Oxygen with or without alternating helmet Non-invasive ventilation for Oxygenation sUpport in acute Respiratory failure (HONOUR): a protocol for a pilot randomised controlled trial
Angriman F, Ferreyro BL, Rochwerg B, Sklar M, Adhikari N, Bagshaw SM, Brochard L, Cuthbertson B, Del Sorbo L, Fowler R
Beyond borders: the impact of international fellowships on professional and personal development.
von Düring S, Ratano D, Cuthbertson B
Short-duration selective decontamination of the digestive tract infection control does not contribute to increased antimicrobial resistance burden in a pilot cluster randomised trial (the ARCTIC Study).
Kean IRL, Clark JA, Zhang Z, Daubney E, White D, Ferrando-Vivas P, Milla G, Cuthbertson B, Pappachan J, Klein N, Mouncey P, Rowan K, Myburgh J, Gouliouris T, Baker S, Parkhill J, Pathan N, Arctic Research Team
Research priorities for the study of atrial fibrillation during acute and critical illness: recommendations from the Symposium on Atrial Fibrillation in Acute and Critical Care
Sibley S, Atzema C, Balik M, Bedford J, Conen D, Garside T, Johnston B, Kanji S, Landry C, McIntyre W
De-adoption of chlorhexidine oral care and ICU mortality. Authors' reply.
Dale C, Cuthbertson B
Long-term mortality following complications after elective surgery: a secondary analysis of pooled data from two prospective cohort studies.
Fowler AJ, Wan YI, Prowle JR, Chew M, Campbell D, Cuthbertson B, Wijeysundera DN, Pearse R, Abbott T
Use of selective gut decontamination in critically ill children: protocol for the Paediatric Intensive Care and Infection Control (PICnIC) pilot study.
Brown A, Ferrando P, Popa M, de la Fuente GM, Pappachan J, Cuthbertson B, Drikite L, Feltbower R, Gouliouris T, Sale I, Shulman R, Tume LN, Myburgh J, Woolfall K, Harrison DA, Mouncey PR, Rowan KM, Pathan N
The PLATform for INnovative Multicentre trials for comorbid chronic Pain and Depressive disorders (PLATINuM-PD)
Principal investigators: Ladha, Karim; Clarke, Hance A; Goel, Akash; Husain, Muhammad I; Rosenblat, Joshua D; Rosenbloom, Brittany; Voineskos, Daphne; Zrenner, Christoph D
Keywords: Chronic Pain; Depression; Platform Trial
From Best Evidence to Best Practice: Advancing ICU Sedation Through SAVE-ICU Knowledge Translation
Principal investigators: Jerath, Angela
Keywords: Critical Care; Knowledge Planning; Knowledge Synthesis; Knowledge Translation; Outcomes; Sedation
The Randomized Embedded Multifactorial Adaptive Platform Trial in Community-Acquired Pneumonia (REMAP-CAP): Enshrining a Global Pandemic Research Response to COVID-19 and Beyond
Principal investigators: Marshall, John C; Dalziel, Sandra; Kho, Michelle E; Lamontagne, Francois; Leligdowicz, Aleksandra; Murthy, Srinivas; Park, Jay; Smith, Kathleen F
Keywords: Acute Organ Dysfunction; Covid-19; Critical Illness; Global Health; Hemodynamic Management; Platform Trial; Research Collaboration; Ventilatory Support
Randomized Embedded Multifactorial Adaptive Platform Trial of Community Acquired Pneumonia
Principal investigators: Murthy, Srinivas; Dalziel, Sandra; Kho, Michelle E; Marshall, John C; Park, Jay; Smith, Kathleen F
Keywords: Community Acquired Pneumonia; Critical Care; Randomized Clinical Trial
Canadian Critical Care Trials Group COVID-19 Response: defining critical care capacity in Canada; testing treatments through large-scale adaptive clinical trials; & establishing the evidence base to inform clinical and health system management decisions
Principal investigators: Fowler, Robert A; Adhikari, Neill K; Archambault, Patrick; Bagshaw, Sean M; Binnie, Alexandra; Chasse, Michael; Cook, Deborah J; Daneman, Nick; Fiest, Kirsten M; Fox-Robichaud, Alison E; Goligher, Ewan C; Herridge, Margaret S; Kho, Michelle E; Lamontagne, Francois; Lawler, Patrick R; Lee, Todd C; Marshall, John C; McDonald, Emily G; McNally, James D; Meade, Maureen O; Mehta, Sangeeta; Menon, Kusum; Murthy, Srinivas; O'Hearn, Katharine J; Piquette, Dominique; Rochwerg, Bram N; Russell, James A; Tsang, Jennifer L; Turgeon, Alexis F; Wollny, Krista; Yada, Nicole; Zarychanski, Ryan
Keywords: Clinical Trials; Covid-19; Network
Advancing Brain Outcomes in pediatric critically ill patients sedated with Volatile AnEsthestic Agents: A pilot multicentre randomized controlled trial (ABOVE Trial).
Principal investigators: Jerath, Angela; Cuthbertson, Brian H; Lalgudi Ganesan, Saptharishi; McKinnon, Nicole K; Slessarev, Marat
Keywords: Clinical Trial; Critical Care; Pediatric; Sedation
The Randomized Embedded Multifactorial Adaptive Platform Trial in Community-Acquired Pneumonia (REMAP-CAP): Enshrining a Global Pandemic Research Response to COVID-19 and Beyond
Principal investigators: Marshall, John C; Dalziel, Sandra; Kho, Michelle E; Lamontagne, Francois; Leligdowicz, Aleksandra; Murthy, Srinivas; Park, Jay; Smith, Kathleen F
Keywords: Acute Organ Dysfunction; Covid-19; Critical Illness; Global Health; Hemodynamic Management; Platform Trial; Research Collaboration; Ventilatory Support
Randomized Embedded Multifactorial Adaptive Platform Trial of Community Acquired Pneumonia
Principal investigators: Murthy, Srinivas; Dalziel, Sandra; Kho, Michelle E; Marshall, John C; Park, Jay; Smith, Kathleen F
Keywords: Community Acquired Pneumonia; Critical Care; Randomized Clinical Trial
Advancing Brain Outcomes in pediatric critically ill patients sedated with Volatile AnEsthestic Agents: A pilot multicentre randomized controlled trial (ABOVE Trial).
Principal investigators: Jerath, Angela; Cuthbertson, Brian H; Lalgudi Ganesan, Saptharishi; McKinnon, Nicole K; Slessarev, Marat
Keywords: Clinical Trial; Critical Care; Pediatric; Sedation
Lung and Diaphragm Protection in Acute Hypoxemic Respiratory Failure: the LANDMARK II Pilot and Feasibility Randomized Clinical Trial
Principal investigators: Goligher, Ewan C; Fan, Eddy
Keywords: Adaptive Platform Clinical Trial; Diaphragm-Protective Ventilation; Hypoxemic Respiratory Failure; Lung-Protective Ventilation
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Critical Care Medicine
- Medicine
- Department of Anesthesiology and Pain Medicine
- Health Research Methods, Evidence, and Impact
- Anesthesiology and Pain Management
- Biostatistics Division
- Department of Medicine
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Angela Jerath
Anesthesiology and Pain Management
2 shared papers, latest 2025
Anna Heath
Biostatistics Division
2 shared papers, latest 2026
John Muscedere
Critical Care Medicine
2 shared papers, latest 2025
Anna Heath
Faculty
2 shared papers, latest 2026
Marat Slessarev
Medicine
2 shared papers, latest 2025
Eddy Fan
Department of Medicine
2 shared papers, latest 2026
Robert Fowler
Infectious Diseases/Internal Medicine
2 shared papers, latest 2025
Laurent Brochard
Critical Care Medicine
1 shared papers, latest 2025
Srinivas Murthy
Faculty
1 shared papers, latest 2021
Ken Parhar
Critical Care Medicine
1 shared papers, latest 2025
Frederick D'Aragon
Faculty
1 shared papers, latest 2025
Salmaan Kanji
Department of Medicine
1 shared papers, latest 2024
Lorenzo Del Sorbo
Faculty
1 shared papers, latest 2025
Sangeeta Mehta
Faculty
1 shared papers, latest 2025
Laveena Munshi
Critical Care Medicine
1 shared papers, latest 2025
Stephanie Sibley
Critical Care Medicine
1 shared papers, latest 2024
Michael Sklar
Anesthesiology and Pain Management
1 shared papers, latest 2025
Ian Randall
Department of Anesthesiology and Pain Medicine
1 shared papers, latest 2025
Yongdong Ouyang
Biostatistics Division
1 shared papers, latest 2025
Neill Adhikari
Anesthesiology and Pain Management
1 shared papers, latest 2025
Craig Dale
Faculty
1 shared papers, latest 2022
Jennifer Tsang
Medicine
1 shared papers, latest 2024
Bram Rochwerg
Health Research Methods, Evidence, and Impact
1 shared papers, latest 2025
Michael Ke Wang
Health Research Methods, Evidence, and Impact
1 shared papers, latest 2024
David Conen
Medicine
1 shared papers, latest 2024
William McIntyre
Medicine
1 shared papers, latest 2024
Karen Burns
Health Research Methods, Evidence, and Impact
1 shared papers, latest 2011
Michael Wang
Medicine
1 shared papers, latest 2024
Clare Atzema
Emergency Medicine
1 shared papers, latest 2024
Louise Rose
Critical Care Medicine
1 shared papers, latest 2014
Deborah Cook
Medicine
1 shared papers, latest 2011
Claudio Martin
Faculty
1 shared papers, latest 2025
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Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.