Faculty profile
Michael Sklar
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Research
Latest papers
Development and implementation of a severe accidental hypothermia resuscitation pathway in an urban Canadian emergency department: a quality improvement initiative.
CJEM · 2026
Induction Agents for Tracheal Intubation of Critically Ill Patients: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Chest · 2026
Multi-center randomized superiority clinical trial in the early phase of mechanically ventilated patients to preserve diaphragm thickness using non-invasive magnetic phrenic nerve stimulation: STIMIT ACTIVATOR 1 pivotal trial.
Trials · 2025
Latest funding
- $20,000
IMPACT-CC: Increasing Meaningful Participation and Access to Critical Care Trials in Community Intensive Care Units
CIHR · 2025 · Co-investigator
- $455,793
Positive End-Expiratory Pressure during Extracorporeal Life Support for Acute Hypoxemic Respiratory Failure: the PEEP in ECLS Randomized Clinical Trial
CIHR · 2024 · Principal investigator
- $401,625
Effects of an Open Lung protective protective EXTubation strategy compared to a conventional extubation strategy on postoperative pulmonary complications after general anesthesia as part of a comprehensive lung protective ventilation strategy: a multicenter pilot randomized controlled trial (OLEXT-3 study)
CIHR · 2023 · Co-investigator
12 publications.
Development and implementation of a severe accidental hypothermia resuscitation pathway in an urban Canadian emergency department: a quality improvement initiative.
Dell E, Vaillancourt S, Warsi F, Sklar M, Yanagawa B, Alli A, Mok G
Induction Agents for Tracheal Intubation of Critically Ill Patients: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
McDougall G, Forestell B, Sadeghirad B, Kuriyama A, Sivananathajothy P, Flindall H, Choi J, Centofanti J, Myatra SN, Prakash J
Multi-center randomized superiority clinical trial in the early phase of mechanically ventilated patients to preserve diaphragm thickness using non-invasive magnetic phrenic nerve stimulation: STIMIT ACTIVATOR 1 pivotal trial.
Schreiber AF, Subirà C, Sklar M, Santos M, Ko M, Panelli A, Schaller SJ, Theodore D, Rowley DD, Watson D, Bonde P, Baedorf Kassis EN, Talmor DS, Ranieri M, Goligher EC, Slutsky A, Brochard LJ
High-flow nasal Oxygen with or without alternating helmet Non-invasive ventilation for Oxygenation sUpport in acute Respiratory failure (HONOUR): a protocol for a pilot randomised controlled trial
Angriman F, Ferreyro BL, Rochwerg B, Sklar M, Adhikari N, Bagshaw SM, Brochard L, Cuthbertson B, Del Sorbo L, Fowler R
The association between nutritional risk index and ICU outcomes across hematologic malignancy patients with acute respiratory failure.
Kundu R, Seeger R, Elfassy MD, Rozenberg D, Ahluwalia N, Detsky ME, Ferreyro BL, Mehta S, Law AD, Minden M, Prica A, Sklar M, Munshi L
Machine learning approaches to the human metabolome in sepsis identify metabolic links with survival.
Kosyakovsky LB, Somerset E, Rogers AJ, Sklar M, Mayers JR, Toma A, Szekely Y, Soussi S, Wang B, Fan CS, Baron RM, Lawler PR
Cognitive Impairment and Delirium in Older Patients Undergoing Major Head and Neck Surgery.
Goldstein DP, Blasco M, de Almeida J, Su J, Xu W, Cohen M, Sklar M, Alibhai S
Evaluation of Sarcopenia in Older Patients Undergoing Head and Neck Cancer Surgery.
Orzell S, Verhaaren BFJ, Grewal R, Sklar M, Irish JC, Gilbert R, Brown D, Gullane P, de Almeida JR, Yu E, Su J, Xu W, Alibhai SMH, Goldstein DP
Trials directly comparing alternative spontaneous breathing trial techniques: a systematic review and meta-analysis
Burns KEA, Soliman I, Adhikari NKJ, Zwein A, Wong JTY, Gomez-Builes C, Pellegrini JA, Chen L, Rittayamai N, Sklar M
Different Definitions of Lung Recruitment by Computed Tomography Scan.
Chen L, Sklar M, Dres M, Goligher EC
IMPACT-CC: Increasing Meaningful Participation and Access to Critical Care Trials in Community Intensive Care Units
Principal investigators: Tsang, Jennifer L; Orlando, Elaina; Binnie, Alexandra; O'Grady, Heather
Keywords: Clinical Trials; Community Icu; Critical Care; Equity; Platform Trials; Research Capacity Building
Positive End-Expiratory Pressure during Extracorporeal Life Support for Acute Hypoxemic Respiratory Failure: the PEEP in ECLS Randomized Clinical Trial
Principal investigators: Del Sorbo, Lorenzo; Brochard, Laurent J; Goligher, Ewan C; Greendyk, Richard A; Sklar, Michael C
Keywords: Extracorporeal Life Support; Mechanical Ventilation; Positive End-Expiratory Pressure
Effects of an Open Lung protective protective EXTubation strategy compared to a conventional extubation strategy on postoperative pulmonary complications after general anesthesia as part of a comprehensive lung protective ventilation strategy: a multicenter pilot randomized controlled trial (OLEXT-3 study)
Principal investigators: Girard, Martin; Chasse, Michael
Keywords: Extubation; General Anesthesia; Lung-Protective Ventilation; Postoperative Pulmonary Complications
EXtubation related complications - an international observational study To Understand impact and BEst practices - the EXTUBE study
Principal investigators: Parotto, Matteo; Adhikari, Neill K; Law, John A; Sklar, Michael C; Tsang, Jennifer L; Wijeysundera, Duminda N
Keywords: Airway Management; Anesthesia; Complications; Critical Care; Epidemiology; Extubation; Global; Patient Safety; Point Prevalence; Prospective Cohort
Driving Pressure-Limited Ventilation in Hypoxemic Respiratory Failure: the DRIVE RCT
Principal investigators: Goligher, Ewan C; Fan, Eddy; Ferguson, Niall D; Sahetya, Sarina
Keywords: Adaptive Platform Clinical Trial; Hypoxemic Respiratory Failure; Lung-Protective Ventilation
Evaluating Subphenotypes in Immunocompromised Patients with Acute Respiratory Failure
Principal investigators: Munshi, Laveena; Fan, Eddy; Ferreyro, Bruno L
Keywords: Acute Respiratory Failure; Biomarkers; Immunocompromised; Latent Class Analysis; Phenotypes; Respiratory Mechanics
Driving Pressure-Limited Ventilation in Hypoxemic Respiratory Failure: the DRIVE RCT
Principal investigators: Goligher, Ewan C; Fan, Eddy; Ferguson, Niall D; Heath, Anna; Sahetya, Sarina
Keywords: Adaptive Platform Clinical Trial; Hypoxemic Respiratory Failure; Lung-Protective Ventilation
Lung and Diaphragm Protection in Acute Hypoxemic Respiratory Failure: the LANDMARK II Pilot and Feasibility Randomized Clinical Trial
Principal investigators: Goligher, Ewan C; Fan, Eddy
Keywords: Adaptive Platform Clinical Trial; Diaphragm-Protective Ventilation; Hypoxemic Respiratory Failure; Lung-Protective Ventilation
Driving Pressure-Limited Ventilation in Hypoxemic Respiratory Failure: the DRIVE RCT
Principal investigators: Goligher, Ewan C; Fan, Eddy; Ferguson, Niall D; Heath, Anna; Sahetya, Sarina
Keywords: Adaptive Platform Clinical Trial; Hypoxemic Respiratory Failure; Lung-Protective Ventilation
Lung and Diaphragm Protection in Acute Hypoxemic Respiratory Failure: the LANDMARK II Pilot and Feasibility Randomized Clinical Trial
Principal investigators: Goligher, Ewan C; Fan, Eddy
Keywords: Adaptive Platform Clinical Trial; Diaphragm-Protective Ventilation; Hypoxemic Respiratory Failure; Lung-Protective Ventilation
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Critical Care Medicine
- Health Research Methods, Evidence, and Impact
- Anesthesiology and Pain Management
- Anesthesia
- Biostatistics Division
- Human Kinetics
- Department of Anesthesiology and Pain Medicine
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Wei Xu
Biostatistics Division
2 shared papers, latest 2022
Sangeeta Mehta
Faculty
2 shared papers, latest 2025
Laveena Munshi
Critical Care Medicine
2 shared papers, latest 2025
John de Almeida
Radiation Oncology
1 shared papers, latest 2022
Sameer Sharif
Medicine
1 shared papers, latest 2026
Karen Burns
Health Research Methods, Evidence, and Impact
1 shared papers, latest 2017
Akira Kuriyama
Health Research Methods, Evidence, and Impact
1 shared papers, latest 2026
Robert Fowler
Infectious Diseases/Internal Medicine
1 shared papers, latest 2025
Brian Cuthbertson
Department of Anesthesiology and Pain Medicine
1 shared papers, latest 2025
Shabbir Alibhai
Li Ka Shing Knowledge
1 shared papers, latest 2022
Arthur Slutsky
Critical Care Medicine
1 shared papers, latest 2025
Neill Adhikari
Anesthesiology and Pain Management
1 shared papers, latest 2025
Behnam Sadeghirad
Anesthesia
1 shared papers, latest 2026
Mark Minden
Medical Biophysics
1 shared papers, latest 2023
Bobby Yanagawa
Faculty
1 shared papers, latest 2026
Andrew Seely
Human Kinetics
1 shared papers, latest 2025
Laurent Brochard
Critical Care Medicine
1 shared papers, latest 2025
Ken Parhar
Critical Care Medicine
1 shared papers, latest 2025
Marat Slessarev
Medicine
1 shared papers, latest 2025
Lorenzo Del Sorbo
Faculty
1 shared papers, latest 2025
Dmitry Rozenberg
Medicine/Respirology
1 shared papers, latest 2023
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