Faculty profile

Lorenzo Del Sorbo

ResearcherUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.

Lorenzo Del Sorbo

Researcher

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
44 publications in the last five years, latest in 2026.
Senior (last) author on 9 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

112

Publications

1,676

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Extracorporeal Life Support Mechanical Ventilation Positive End-Expiratory Pressure Lung Transplantation Organ Donors Prone Position

Latest papers

Digital twins of ex vivo human lungs enable accurate and personalized evaluation of therapeutic efficacy.
Nature biotechnology · 2026
Economic evaluation of ex-vivo lung perfusion for lung transplantation: A cost-utility analysis from a large Canadian center.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2026
Airway Occlusions to Measure Inspiratory Effort, Respiratory Drive, and Lung Mechanics During Noninvasive Ventilation.
American journal of respiratory and critical care medicine · 2026

All 112 publications

Latest funding

Clinical Implications of Potentially Injurious Patient-Ventilator Interaction Phenotypes. A longitudinal cohort study embedded within a platform of clinical trials testing different ventilation strategies.
CIHR · 2025 · Co-investigator
$661,726
Precision medicine Adaptive Network platform Trial in Hypoxemic acutE respiratory failuRe (PANTHER)
CIHR · 2025 · Co-investigator
$2,952,135
Precision medicine Adaptive Network platform Trial in Hypoxemic acutE respiratory failuRe (PANTHER)
CIHR · 2025 · Co-investigator
$100,000

All 32 grants and awards

112 publications.

Digital twins of ex vivo human lungs enable accurate and personalized evaluation of therapeutic efficacy.

Zhou X, Wang B, Wei Y, Hacker S, Kim S, Borrillo T, McCaig A, Ahmed H, Ren Y, Hough O, Orsini L, Chao BT, McInnis M, Cypel M, Liu M, Yeung JC, Del Sorbo L, Keshavjee S, Sage AT

Nature biotechnology2026

DOI: 10.1038/s41587-026-03121-4 PMID: 42082790

Economic evaluation of ex-vivo lung perfusion for lung transplantation: A cost-utility analysis from a large Canadian center.

Peel JK, Naimark DMJ, Pullenayegum EM, Singer LG, Aversa M, Liu M, Del Sorbo L, Cypel M, Barrett K, Keshavjee S, Sander B

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2026

DOI: 10.1016/j.healun.2026.01.032 PMID: 41663040

Airway Occlusions to Measure Inspiratory Effort, Respiratory Drive, and Lung Mechanics During Noninvasive Ventilation.

Murgolo F, Grieco DL, Soloperto R, Bertoni M, Spadaro S, Bartolomeo N, Pettenuzzo T, Beloncle F, Venkatapen D, Cardu A, Rosà T, Iacovelli C, Navalesi P, Maggiore SM, Goligher EC, Ranieri VM, Del Sorbo L, Antonelli M, Grasso S

American journal of respiratory and critical care medicine2026

DOI: 10.1093/ajrccm/aamag293 PMID: 42287717

A consensus of international experts on definition, sampling, treatment, and prevention of peripheral extracorporeal membrane oxygenation cannula-site infection obtained by the Delphi method: the SAVECMO study.

Masi P, Abrams D, Hssain AA, Balik M, Barrett NA, Broman LM, Camporota L, Chen YS, Combes A, De Backer D, Del Sorbo L, Diaz R, Donker DW, Douflé G, Fan E, Fraser JF, Giani M, Giraud R, Grasselli G, Hraiech S, Lorusso R, MacLaren G, Marcus JE, Martucci G, Mendes PV, Ohshimo S, Paiva JA, Park S, Ramanathan K, Riera J, Roncon-Albuquerque R, Salazar L, Schmidt M, Shah A, Shekar K, Supady A, Taccone FS, Tonna JE, Yeung Ng P, Yusuff H, Luyt CE, For EuroELSO

Intensive care medicine2026

DOI: 10.1007/s00134-025-08269-2 PMID: 41504890

Careful ventilation in acute respiratory distress syndrome: the protocol of the CAVIARDS international multicentre randomised basket trial

Coudroy R, Telias I, Jonkman A, Thille AW, Diehl J, Péron N, Ko M, Bourion A-A, Tiribelli N, Fredes S

BMJ Open20261 citations

DOI: 10.1136/bmjopen-2025-115775

Association of respiratory drive and effort with mortality and time to discharge in patients on mechanical ventilation in Canada: a longitudinal, prospective, registry-based cohort study.

Dianti J, Lovblom LE, Iftikhar MA, Sahetya S, Telias I, Urner M, Del Sorbo L, Amato MBP, Slutsky AS, Brochard L, Ferguson ND, Fan E, Goligher EC

The Lancet. Respiratory medicine2025

DOI: 10.1016/s2213-2600(25)00297-8 PMID: 40983065

Serum Ammonia Screening and Donor Mollicutes Detection for Hyperammonemia Syndrome Post-Lung Transplantation: A Prospective Observational Study.

Walti LN, Ng CF, Kaur S, Almansour S, Mazzulli T, Bitterman R, Sidhu A, Keshavjee S, Chaparro C, Martinu T, Tikkanen J, Del Sorbo L, Husain S

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America2025

DOI: 10.1093/cid/ciaf078 PMID: 39985813

Continuous On-Demand Diaphragm Neurostimulation to Prevent Diaphragm Inactivity During Mechanical Ventilation: A Phase 1 Clinical Trial (STIMULUS).

Morris IS, Bassi T, Bellissimo CA, Bootjeamjai P, Roman-Sarita G, de Perrot M, Donahoe L, McRae K, Dianti J, Del Sorbo L, Keshavjee S, Cypel M, Reynolds SC, Dres M, Thakkar V, Mehta N, Brochard L, Ferguson ND, Goligher EC

American journal of respiratory and critical care medicine2025

DOI: 10.1164/rccm.202407-1483oc PMID: 40043207

Evidence-based personalised medicine in critical care: a framework for quantifying and applying individualised treatment effects in patients who are critically ill

Munroe ES, Spicer A, Castellvi-Font A, Zalucky A, Dianti J, Linck EG, Talisa V, Urner M, Angus DC, Baedorf-Kassis E

The Lancet Respiratory Medicine202546 citations

DOI: 10.1016/s2213-2600(25)00054-2

Sepsis subtypes and differential treatment response to vitamin C: biological sub-study of the LOVIT trial

Rynne J, Mosavie M, Masse M-H, Ménard J, Battista M-C, Maslove DM, del Sorbo L, St-Arnaud C, DAragon F, Fox-Robichaud A

Intensive Care Medicine202521 citations

DOI: 10.1007/s00134-024-07733-9

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2024

Subject: Prospective PhD student: Extracorporeal Life Support Dear Professor Del Sorbo, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Digital twins of ex vivo human lungs enable accurate and personalized evaluation of therapeutic efficacy." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Positive End-Expiratory Pressure during Extracorporeal Life Support for Acute Hypoxemic Respiratory Failure: the PEEP in ECLS Randomized Clinical Trial" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

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Lorenzo Del Sorbo

Research

Latest papers

Latest funding

Digital twins of ex vivo human lungs enable accurate and personalized evaluation of therapeutic efficacy.

Economic evaluation of ex-vivo lung perfusion for lung transplantation: A cost-utility analysis from a large Canadian center.

Airway Occlusions to Measure Inspiratory Effort, Respiratory Drive, and Lung Mechanics During Noninvasive Ventilation.

A consensus of international experts on definition, sampling, treatment, and prevention of peripheral extracorporeal membrane oxygenation cannula-site infection obtained by the Delphi method: the SAVECMO study.

Careful ventilation in acute respiratory distress syndrome: the protocol of the CAVIARDS international multicentre randomised basket trial

Association of respiratory drive and effort with mortality and time to discharge in patients on mechanical ventilation in Canada: a longitudinal, prospective, registry-based cohort study.

Serum Ammonia Screening and Donor Mollicutes Detection for Hyperammonemia Syndrome Post-Lung Transplantation: A Prospective Observational Study.

Continuous On-Demand Diaphragm Neurostimulation to Prevent Diaphragm Inactivity During Mechanical Ventilation: A Phase 1 Clinical Trial (STIMULUS).

Evidence-based personalised medicine in critical care: a framework for quantifying and applying individualised treatment effects in patients who are critically ill

Sepsis subtypes and differential treatment response to vitamin C: biological sub-study of the LOVIT trial

Frequent collaborators

Eddy Fan

Shaf Keshavjee

Marcelo Cypel

Laurent Brochard

Laveena Munshi

Mingyao Liu

Shahid Husain

Bram Rochwerg

Sangeeta Mehta

Maureen Meade

Martin Urner

Irene Telias

Ricardo Teijeiro Paradis

Haibo Zhang

Tereza Martinu

Hannah Wunsch

John Granton

BO WANG

Gordon Guyatt

Lisa Burry

Deborah Cook

Beate Sander

Tony Mazzulli

Ruxandra Pinto

Matteo Parotto

Stefanos Voglis

Marat Slessarev

Margaret Herridge

Emilie Belley-Cote

Aizhou Wang

Divya Sharma

Andy Pan

Sheila Riazi

Anna Heath

Rosane Nisenbaum

Brodie Nolan

John Muscedere

Justyna Bartoszko

Andrew Sage

Michael Sklar