Research
Read how they describe their research on their University of Toronto profile.
Latest papers
The development and impact of an innovative graduate program to promote entry to physiology-related careers: the Master of Health Science in Medical Physiology.
Advances in physiology education · 2026 · senior author
Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty.
Cell metabolism · 2020
Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3.
PLoS biology · 2019
Latest funding
- $1,036,576
The Impact of Nutrient Excess on Hypothalamic Reproductive Neurons.
CIHR · 2026 · Nominated PI
- $20,000
Lab2Market - Investigating the potential appetite-supressing effects of a novel cytokinin.
NSERC · 2022 · Principal investigator
- $105,000
Delineating the potent appetite suppressant effects of a novel phytohormone in defined hypothalamic neurons and mouse models.
CIHR · 2022 · Supervisor
5 publications.
The development and impact of an innovative graduate program to promote entry to physiology-related careers: the Master of Health Science in Medical Physiology.
Miliotis H, Buchan A, Wittnich C, Cox B, Brubaker PL, Giacca A, Belsham D
Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty.
Heras V, Castellano JM, Fernandois D, Velasco I, Rodríguez-Vazquez E, Roa J, Vazquez MJ, Ruiz-Pino F, Rubio M, Pineda R, Torres E, Avendaño MS, Paredes A, Pinilla L, Belsham D, Diéguez C, Gaytán F, Casals N, López M, Tena-Sempere M
Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3.
Heras V, Sangiao-Alvarellos S, Manfredi-Lozano M, Sanchez-Tapia MJ, Ruiz-Pino F, Roa J, Lara-Chica M, Morrugares-Carmona R, Jouy N, Abreu AP, Prevot V, Belsham D, Vazquez MJ, Calzado MA, Pinilla L, Gaytan F, Latronico AC, Kaiser UB, Castellano JM, Tena-Sempere M
5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary.
Khare T, Pai S, Koncevicius K, Pal M, Kriukiene E, Liutkeviciute Z, Irimia M, Jia P, Ptak C, Xia M, Tice R, Tochigi M, Moréra S, Nazarians A, Belsham D, Wong AH, Blencowe BJ, Wang SC, Kapranov P, Kustra R, Labrie V, Klimasauskas S, Petronis A
Teneurin proteins possess a carboxy terminal sequence with neuromodulatory activity.
Wang L, Rotzinger S, Al Chawaf A, Elias CF, Barsyte-Lovejoy D, Qian X, Wang NC, De Cristofaro A, Belsham D, Bittencourt JC, Vaccarino F, Lovejoy DA
The Impact of Nutrient Excess on Hypothalamic Reproductive Neurons.
Principal investigators: Belsham, Denise D
Keywords: Cell Biology; Fatty Acids; Gene Expression; Hypothalamus; Kisspeptin; Neuroendocrinology; Neuropeptides; Obesity; Reproduction; Signal Transduction
Lab2Market - Investigating the potential appetite-supressing effects of a novel cytokinin.
Principal investigators: Belsham, Denise
Delineating the potent appetite suppressant effects of a novel phytohormone in defined hypothalamic neurons and mouse models.
Principal investigators: Zhang, Cindy X
Keywords: Development Of New Treatment For Obesity; Etiology Of Obesity And Overeating; Hypothalamic Neuropeptide Expression; Hypothalamic Regulation On Food Intake; Improve The Health And Quality Of Life For Obese Patients; In Vitro Studies Using Hypothalamic Neuronal Cell Lines; In Vivo Studies Using Transgenic Mouse Models; Neuroendocrinology; Obesity And Metabolism; Regulation Of Energy Balance
Targeting miRNAs in the hypothalamus: Defining their role in obesity and metabolic diseases.
Principal investigators: Belsham, Denise D
Keywords: Cell Biology; Endocrine-Disrupting Chemicals; Fatty Acids; Gene Expression; Hypothalamus; Microrna; Neuroendocrinology; Neuropeptides
Neuroendocrinology
Principal investigators: Belsham, Denise
The Impact of Nutrient Excess and Neuroinflammation on Hypothalamic Reproductive Neurons.
Principal investigators: Belsham, Denise D
Keywords: Anti-Inflammatories; Cell Biology; Gene Expression; Hypothalamus; Microrna; Neuroendocrinology; Neuroinflammation; Neuropeptide; Obesity; Signal Transduction
Circadian Regulation of Neuropeptides from the Hypothalamus.
Principal investigators: Belsham, Denise
International Congress of Neuroendocrinology 2018
Principal investigators: Belsham, Denise D
Keywords: Behaviour; Circadian Rhythm; Metabolism; Neuroendocrinology; Obesity; Reproduction; Stress
Sensing of Peripheral Nutrient Status by the Hypothalamus- from Rodents to Humans.
Principal investigators: Belsham, Denise D
Keywords: Cell Biology; Energy Homeostasis; Hypothalamus; Inflammatory Response; Insulin Resistance; Insulin Signaling; Neuroendocrinology; Neuronal Cell Lines; Neuropeptides; Nutrients
GPR120-dependent activation of hypothalamic anti-diabetic mechanisms by omega-3 fatty acids
Principal investigators: Wellhauser, Leigh A
Keywords: G Protein Coupled Receptors; Hypothalamic Neurons; Inflammation; Insulin; Insulin Resistance; Omega-3 Fatty Acids; Orexogenic Neuropeptides; Reat-Time Polymerase Chain Reaction; Signal Transduction; Type 2 Diabetes Mellitus
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Department of Physiology
- Physiology
- Neurosciences
- Pharmacology and Toxicology
- Biostatistics Division
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Arturas Petronis
Neurosciences
1 shared papers, latest 2012
Dalia Barsyte-Lovejoy
Pharmacology and Toxicology
1 shared papers, latest 2005
Rafal Kustra
Biostatistics Division
1 shared papers, latest 2012
Adria Giacca
Physiology
1 shared papers, latest 2026
Brian Cox
Department of Physiology
1 shared papers, latest 2026
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Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.