Faculty profile

Arturas Petronis

ResearcherNeurosciencesUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Arturas Petronis

Researcher

Neurosciences

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
2 publications in the last five years, latest in 2025.
Principal investigator on 8 research grants (8 CIHR), most recently in 2020.
Supervised 4 trainees who won CIHR awards, most recently in 2013.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Dna Modification Circadian Aging Epigenetics Circadian Epigenomics Epigenetic Aging Huntington'S Disease Bipolar Disorder

Latest papers

Optimization of experimental designs for biological rhythm discovery.
PLoS computational biology · 2025
Characterizing suicidal thoughts and behaviours in individuals presenting to a psychiatric emergency department: a protocol for a multimethod approach for suicide prevention research.
BMJ open · 2025
The crossroads of psychiatric epigenomics.
World psychiatry : official journal of the World Psychiatric Association (WPA) · 2019 · first author

All 35 publications

Latest funding

Investigating the role of accelerated neuronal aging in a mouse model of Huntington's disease from a circadian epigenomic perspective.
CIHR · 2020 · Principal investigator
$100,000
Circadian epigenomic biomarkers for predicting bipolar disorder in high-risk youth
CIHR · 2018 · Nominated PI
$1,499,850
Genetic-epigenetic interactions in lactase non-persistence
CIHR · 2017 · Nominated PI
$598,981

All 12 grants and awards

35 publications.

Optimization of experimental designs for biological rhythm discovery.

Silverthorne T, Carlucci M, Petronis A, Stinchcombe AR

PLoS computational biology2025

DOI: 10.1371/journal.pcbi.1013662 PMID: 41212929

Characterizing suicidal thoughts and behaviours in individuals presenting to a psychiatric emergency department: a protocol for a multimethod approach for suicide prevention research.

Baharikhoob P, Maslej M, Wong AHC, Mulsant B, Blumberger D, Courtney D, Husain MI, Kurdyak P, Kleinman RA, Torfason A, Gajaria A, Diaconescu A, Ma A, Sonley A, Abramovich A, Crawford A, Petronis A, Fage B, Orchard C, Buchman DZ, Liu F, Strudwick G, Lam JSH, Berrevoets M, Mozuraitis M, Reid N, Husain O, Ali S, McMain S, De Luca V, Stergiopoulos V, Lunsky Y, Zaheer J

BMJ open2025

DOI: 10.1136/bmjopen-2024-087561 PMID: 40228850

The crossroads of psychiatric epigenomics.

Petronis A, Labrie V

World psychiatry : official journal of the World Psychiatric Association (WPA)2019First author

DOI: 10.1002/wps.20675 PMID: 31496079

Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer's disease pathology and cognitive symptoms.

Li P, Marshall L, Oh G, Jakubowski JL, Groot D, He Y, Wang T, Petronis A, Labrie V

Nature communications2019

DOI: 10.1038/s41467-019-10101-7 PMID: 31113950

Differential methylation of enhancer at IGF2 is associated with abnormal dopamine synthesis in major psychosis.

Pai S, Li P, Killinger B, Marshall L, Jia P, Liao J, Petronis A, Szabó PE, Labrie V

Nature communications2019

DOI: 10.1038/s41467-019-09786-7 PMID: 31053723

Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice.

Wang DY, Kosowan J, Samsom J, Leung L, Zhang KL, Li YX, Xiong Y, Jin J, Petronis A, Oh G, Wong AHC

Acta pharmacologica Sinica2018

DOI: 10.1038/aps.2017.190 PMID: 29417943

Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome.

Oh E, Jeremian R, Oh G, Groot D, Susic M, Lee K, Foy K, Laird PW, Petronis A, Labrie V

Scientific reports2017

DOI: 10.1038/srep41843 PMID: 28139744

Genetic and epigenetic study of ALS-discordant identical twins with double mutations in SOD1 and ARHGEF28.

Zhang M, Xi Z, Ghani M, Jia P, Pal M, Werynska K, Moreno D, Sato C, Liang Y, Robertson J, Petronis A, Zinman L, Rogaeva E

Journal of neurology, neurosurgery, and psychiatry2016

DOI: 10.1136/jnnp-2016-313592 PMID: 27154192

Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging.

Labrie V, Buske OJ, Oh E, Jeremian R, Ptak C, Gasiūnas G, Maleckas A, Petereit R, Žvirbliene A, Adamonis K, Kriukienė E, Koncevičius K, Gordevičius J, Nair A, Zhang A, Ebrahimi S, Oh G, Šikšnys V, Kupčinskas L, Brudno M, Petronis A

Nature structural & molecular biology2016Senior author

DOI: 10.1038/nsmb.3227 PMID: 27159559

Allele-Skewed DNA Modification in the Brain: Relevance to a Schizophrenia GWAS.

Gagliano SA, Ptak C, Mak DYF, Shamsi M, Oh G, Knight J, Boutros PC, Petronis A

American journal of human genetics2016Senior author

DOI: 10.1016/j.ajhg.2016.03.006 PMID: 27087318

Investigating the role of accelerated neuronal aging in a mouse model of Huntington's disease from a circadian epigenomic perspective.

Principal investigatorCIHR2020Project Grant - PA: Epigenetics/epigenomics in human health or disease

Principal investigators: Oh, Gabriel Hyun Ta; Petronis, Arturas

Keywords: Circadian Epigenomics; Epigenetic Aging; Huntington'S Disease

$100,000

Circadian epigenomic biomarkers for predicting bipolar disorder in high-risk youth

Nominated PICIHR2018Team Grant: CEEHRC Phase II

Principal investigators: Petronis, Arturas; Duffy, Anne C; Oh, Gabriel Hyun Ta; Wong, Albert H

Keywords: Bipolar Disorder; Circadian; Dna Modification; Epigenetics; Etiology; Precision Medicine; Prediction; Psychiatry

$1,499,850

Genetic-epigenetic interactions in lactase non-persistence

Nominated PICIHR2017Operating Grant: Impact Grant : CEEHRC Phase II

Principal investigators: Petronis, Arturas

Keywords: Aging; Disease Models; Dna; Dna Modification; Epigenetics; Lactase Gene; Sequencing

$598,981

Spatiotemporal Dynamics of Chromatin: the Circadian and Aging Connection

Nominated PICIHR2017Team Grant: 4D Nucleome Transformative Collaborative Project

Principal investigators: Petronis, Arturas

Keywords: Aging; Chromatin; Circadian; Histones; Nucleome; Spatial And Temporal Dimension; Transcription

$800,000

The Aging Brain: Circadian, Transcriptomic, and Epigenomic Dimensions

Nominated PICIHR2016Project Grant

Principal investigators: Petronis, Arturas

Keywords: Aging; Alzheimer'S Disease; Brain; Circadian; Dna Modification; Epigenome; Transcriptome

$1,085,591

Mapping epigenetic signatures of aberrant gene splicing in aging mouse and human brain

SupervisorCIHR2013Fellowship - Priority Announcement: Epigenetics

Principal investigators: Pai, Shraddha

Keywords: Aging; Brain Research; Complex Diseases; Computational Methods; Data Analysis; Dna Modifications; Epigenetics; Gene Regulation; Population Genomics

$90,000

Epigenomics of major depressive disorder: dissecting environmental, heritable, and stochastic contributions

Nominated PICIHR2013Operating Grant

Principal investigators: Petronis, Arturas

Keywords: Animal Models; Computational Biology; Dna Modification; Environment; Epigenetic Heritability; Epigenomics; Epimutations; Major Depressive Disorder; Monozygotic Twins; Post-Mortem Brain

$1,191,865

Epigenomics of Schizophrenia

Nominated PICIHR2011Operating Grant

Principal investigators: Petronis, Arturas

Keywords: Bioinformatics; Dna Methylation; Epigenetics; Microarrays; Post-Mortem Brain; Schizophrenia

$1,876,137

The involvement of the epigenome in the mechanism of action and efficacy of pharmacotherapeutic interventions for bipolar disorder

SupervisorCIHR2009CIHR Fellowship

Principal investigators: Labrie, Viviane

Keywords: Antipsychotic; Bipolar Disorder; Brain; Epigenetics; Genetic Animal Model; Microarray-Based Dna Methylation Profiling; Mood Stabilizer; Sodium Bisulfite Sequencing

$135,000

Epigenomic Studies of Twins Discordant for Crohn's Disease

Nominated PICIHR2009Operating Grant

Principal investigators: Petronis, Arturas

Keywords: Crohn'S Disease; Dna Methylation; Epigenetics; Inflammatory Bowel Disease; Twins

$500,358

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Arturas Petronis

Research

Latest papers

Latest funding

Optimization of experimental designs for biological rhythm discovery.

Characterizing suicidal thoughts and behaviours in individuals presenting to a psychiatric emergency department: a protocol for a multimethod approach for suicide prevention research.

The crossroads of psychiatric epigenomics.

Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer's disease pathology and cognitive symptoms.

Differential methylation of enhancer at IGF2 is associated with abnormal dopamine synthesis in major psychosis.

Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice.

Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome.

Genetic and epigenetic study of ALS-discordant identical twins with double mutations in SOD1 and ARHGEF28.

Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging.

Allele-Skewed DNA Modification in the Brain: Relevance to a Schizophrenia GWAS.

Frequent collaborators

Gabriel Oh

Aled Edwards

Benoit Mulsant

Allison Crawford

Gillian Strudwick

Paul Kurdyak

Ekaterina Rogaeva

Alex Abramovich

Shehzad Ali

Darren Courtney

Andreea Diaconescu

Alex Abramovich

Juveria Zaheer

Dalia Barsyte-Lovejoy

Shelley McMain

Marta Maslej

Yona Lunsky

Amy Gajaria

Rafal Kustra

Janice Robertson

Daniel Blumberger

Vicky Stergiopoulos

James Ellis

Fang Liu

Michael Brudno

Yona Lunsky

Vicky Stergiopoulos

Brian Levine

Shelley McMain

Denise Belsham