Iris Cohn, University of Toronto

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Factors Influencing Phenoconversion in CYP-Mediated Drug Metabolism: A Scoping Review.
Pharmacy (Basel, Switzerland) · 2026 · senior author
Optimizing proton-pump inhibitor therapy in paediatric eosinophilic esophagitis through CYP2C19 pharmacogenetic testing.
Journal of the Canadian Association of Gastroenterology · 2025
Impaired Drug Metabolism Caused by Compound Heterozygous Loss-of-Function Variants in CYP3A4: A Case Report.
Clinical pharmacology and therapeutics · 2025

All 14 publications

Latest funding

The BRIDGE Study (Broadening Roles for the Interprofessional Delivery of GEnetics): Establishing best practices for mainstreaming of genetic testing through allied health professional integration
CIHR · 2025 · Co-investigator
$199,360

All 1 grants and awards

14 publications.

01

Factors Influencing Phenoconversion in CYP-Mediated Drug Metabolism: A Scoping Review.

Scodellaro S, Triantafilou S, Cohn I

Pharmacy (Basel, Switzerland)2026Senior author

DOI: 10.3390/pharmacy14040108 PMID: 42506798

02

Optimizing proton-pump inhibitor therapy in paediatric eosinophilic esophagitis through CYP2C19 pharmacogenetic testing.

Scodellaro S, Bortolin KA, Marcon MA, Verstegen RHJ, Da Silva S, Ito S, Lewis T, Jones NL, Cohn I, Hulst JM

Journal of the Canadian Association of Gastroenterology20256 citationsOpen Access

DOI: 10.1093/jcag/gwaf003 PMID: 40567296

03

Impaired Drug Metabolism Caused by Compound Heterozygous Loss-of-Function Variants in CYP3A4: A Case Report.

Kang HB, Cohn I, Mahant S, Costain G, Ito S, Verstegen RHJ

Clinical pharmacology and therapeutics20251 citationsOpen Access

DOI: 10.1002/cpt.3693 PMID: 40296506

04

Pharmacogenetic Testing of Children and Adolescents with Mental Health Conditions: Real-World Experiences.

Kennedy A, Scodellaro S, Verstegen RHJ, Cohn I

Pharmaceuticals (Basel, Switzerland)2025Senior author

DOI: 10.3390/ph18081170 PMID: 40872561

05

Moving Away from One-Size-Fits-All: Assessing the Use of Pharmacogenetic-Guided Medication Therapy in Pediatric Patients with Chronic Pain.

Ruskin D, Szczech K, Scodellaro S, Sun N, Cohn I

Children (Basel, Switzerland)2025Senior author

DOI: 10.3390/children12060721 PMID: 40564679

06

Landscape of TPMT and NUDT15 Pharmacogenetic Variation in a Cohort of Canadian Pediatric Inflammatory Bowel Disease Patients

Kennedy AM, Griffiths AM, Muise AM, Walters TD, Ricciuto A, Huynh HQ, Wine E, Jacobson K, Lawrence S, Carman N

Inflammatory Bowel Diseases202413 citationsSenior authorOpen Access

DOI: 10.1093/ibd/izae109

07

A call for increased inclusivity and global representation in pharmacogenetic testing

April Kennedy, Gabriel Ma, Roozbeh Manshaei, Rebekah Jobling, Raymond H. Kim, Tamorah Rae Lewis, Iris Cohn

npj Genomic Medicine20246 citationsSenior authorOpen Access

DOI: 10.1038/s41525-024-00403-1 PMID: 38388691

08

Pharmacogenetic profiling via genome sequencing in children with medical complexity.

Pan A, Scodellaro S, Khan T, Ushcatz I, Wu W, Curtis M, Cohen E, Cohn RD, Hayeems RZ, Meyn MS, Orkin J, Otal J, Reuter MS, Walker S, Scherer SW, Marshall CR, Cohn I, Costain G

Pediatric research202313 citationsOpen Access

DOI: 10.1038/s41390-022-02313-3 PMID: 36167815

09

Urgent call for guidance supporting gene-based drug dosing in children and adolescents

Sierra Scodellaro, Ronald D. Cohn, Iris Cohn

Paediatrics & Child Health20232 citationsSenior authorOpen Access

DOI: 10.1093/pch/pxad003 PMID: 37287475

10

Association between time to therapeutic INR and length of stay following mechanical heart valve surgery.

Godoy LC, Tomlinson G, Abumuamar AM, Farkouh ME, Rudolph M, Billia F, Cohn I, Marcus G, Kim RH, Rao V, Lawler PR

Journal of cardiac surgery20225 citations

DOI: 10.1111/jocs.16083 PMID: 34662458

The BRIDGE Study (Broadening Roles for the Interprofessional Delivery of GEnetics): Establishing best practices for mainstreaming of genetic testing through allied health professional integration

Co-investigatorCIHR2025Operating Grant: Knowledge Synthesis Grants: Allied Health and Genetics

Principal investigators: Hayeems, Robin Z; Limoges, Jacqueline M

Keywords: Allied Health Professionals; Genetic Service Delivery; Knowledge Syntiesis; Real World Evidence; Workforce Development

$199,360

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Frequent collaborators

Stephen Scherer and Christian Marshall: 210 shared papers
Gregory Costain and Greg Costain: 186 shared papers
Anne Griffiths and Eric Benchimol: 86 shared papers
Anne Griffiths and Kevan Jacobson: 73 shared papers
Eyal Cohen and Julia Orkin: 66 shared papers
Anne Griffiths and Aleixo Muise: 62 shared papers
Gregory Costain and Christian Marshall: 62 shared papers
Christian Marshall and Greg Costain: 60 shared papers
Anne Griffiths and Amanda Ricciuto: 53 shared papers
Michael Farkouh and Lucas Colombo Godoy: 53 shared papers
Eric Benchimol and Kevan Jacobson: 50 shared papers
Stephen Scherer and Gregory Costain: 41 shared papers
Stephen Scherer and Greg Costain: 41 shared papers
Robin Hayeems and Christian Marshall: 36 shared papers
Eric Benchimol and Amanda Ricciuto: 32 shared papers
Robin Hayeems and Gregory Costain: 31 shared papers
Robin Hayeems and Greg Costain: 31 shared papers
Ronald Cohn and Christian Marshall: 26 shared papers
Mary Zachos and Anne Griffiths: 22 shared papers
Ronald Cohn and Gregory Costain: 21 shared papers
Ronald Cohn and Greg Costain: 21 shared papers
Amanda Ricciuto and Kevan Jacobson: 17 shared papers
Eric Benchimol and Aleixo Muise: 16 shared papers
Stephen Scherer and Raymond Kim: 16 shared papers
Aleixo Muise and Amanda Ricciuto: 14 shared papers
Raymond Kim and Eriskay Liston: 14 shared papers
Eriskay Liston and Christian Marshall: 13 shared papers
Robin Hayeems and Eriskay Liston: 11 shared papers
Eyal Cohen and Robin Hayeems: 10 shared papers
Raymond Kim and Christian Marshall: 10 shared papers
Eyal Cohen and Ronald Cohn: 9 shared papers
Stephen Scherer and David Chitayat: 9 shared papers
David Chitayat and Christian Marshall: 9 shared papers
Mary Zachos and Eric Benchimol: 8 shared papers
David Chitayat and Robin Hayeems: 8 shared papers
Julia Orkin and Gregory Costain: 7 shared papers
Julia Orkin and Greg Costain: 7 shared papers
Mary Zachos and Amanda Ricciuto: 6 shared papers
Michael Farkouh and George Tomlinson: 6 shared papers
Filio Billia and Michael Farkouh: 4 shared papers
Filio Billia and George Tomlinson: 4 shared papers
Filio Billia and Raymond Kim: 4 shared papers
Shinya Ito and Iris Cohn: 4 shared papers
Robin Hayeems and Iris Cohn: 4 shared papers
Raymond Kim and Iris Cohn: 4 shared papers
Shinya Ito and Ronald Cohn: 3 shared papers
Shinya Ito and Robin Hayeems: 3 shared papers
Shinya Ito and Jessie Hulst: 3 shared papers
Ronald Cohn and Iris Cohn: 3 shared papers
Anne Griffiths and Jessie Hulst: 2 shared papers
Aleixo Muise and Jessie Hulst: 2 shared papers
Stephen Scherer and Iris Cohn: 2 shared papers
Filio Billia and Lucas Colombo Godoy: 2 shared papers
Gregory Costain and Iris Cohn: 2 shared papers
Eriskay Liston and Iris Cohn: 2 shared papers
Christian Marshall and Iris Cohn: 2 shared papers
Iris Cohn and Greg Costain: 2 shared papers
Iris Cohn and Tamorah Lewis: 2 shared papers
Mary Zachos and Iris Cohn: 1 shared paper
Eyal Cohen and Iris Cohn: 1 shared paper
Anne Griffiths and George Tomlinson: 1 shared paper
Anne Griffiths and Iris Cohn: 1 shared paper
Eric Benchimol and Iris Cohn: 1 shared paper
Aleixo Muise and Iris Cohn: 1 shared paper
David Chitayat and Iris Cohn: 1 shared paper
Filio Billia and Iris Cohn: 1 shared paper
Shinya Ito and Tamorah Lewis: 1 shared paper
Michael Farkouh and Iris Cohn: 1 shared paper
Ronald Cohn and Tamorah Lewis: 1 shared paper
George Tomlinson and Lucas Colombo Godoy: 1 shared paper
George Tomlinson and Iris Cohn: 1 shared paper
Jessie Hulst and Iris Cohn: 1 shared paper
Julia Orkin and Iris Cohn: 1 shared paper
Amanda Ricciuto and Iris Cohn: 1 shared paper
Lucas Colombo Godoy and Iris Cohn: 1 shared paper
Kevan Jacobson and Iris Cohn: 1 shared paper

Department of Paediatrics
Department of Medicine
Department of Molecular Genetics
Institute of Health Policy, Management, and Evaluation
Department of Pediatrics
Department of Laboratory Medicine & Pathobiology
Department of Pharmacology and Toxicology
Other

1 shared papers, latest 2024

Wael El-Matary

Faculty

1 shared papers, latest 2024

Vivek Rao

Department of Surgery

1 shared papers, latest 2022

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Subject: Prospective PhD student Dear Professor Cohn, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Factors Influencing Phenoconversion in CYP-Mediated Drug Metabolism: A Scoping Review." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]