Faculty profile
Anne Griffiths
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Research
Latest papers
Clinical and radiological outcomes of ustekinumab in pediatric perianal Crohn's disease: a multicenter retrospective study from the Pediatric IBD Porto Group of ESPGHAN.
Inflammatory bowel diseases · 2026
Neutrophil-to-Lymphocyte Ratio at Diagnosis Predicts Colonoscopic Activity in Pediatric Inflammatory Bowel Diseases.
Clinical and translational gastroenterology · 2025
Outcomes and Endpoints of Postoperative Recurrence in Crohn's Disease: Systematic Review and Consensus Conference.
Journal of Crohn's & colitis · 2024
Latest funding
- $2,955,578
Developing Targeted Therapies for Rare and Common Forms of Inflammatory Bowel Disease
CIHR · 2018 · Co-investigator
- $1,950,000
Elucidating the Gene-Environment Interactions that drive Autoimmune Disease among South Asian Canadians - The GEMINI Program.
CIHR · 2015 · Co-investigator
- $100,000
Economic Evaluation of Early Intervention with anti-Tumour Necrosis Factor Alpha Medications in Children with Crohn's disease
CIHR · 2014 · Co-investigator
57 publications.
Clinical and radiological outcomes of ustekinumab in pediatric perianal Crohn's disease: a multicenter retrospective study from the Pediatric IBD Porto Group of ESPGHAN.
Orlin I, Younis B, Gasparetto M, Yerushalmy-Feler A, Norsa L, Sokollik C, Rohani P, Zárubová K, D'Arcangelo G, Pochesci S, Lozano-Ruf A, Kolho KL, Griffiths A, Rinawi F
Neutrophil-to-Lymphocyte Ratio at Diagnosis Predicts Colonoscopic Activity in Pediatric Inflammatory Bowel Diseases.
Aziz B, Belaghi R, Huynh H, Jacobson K, Mack DR, Deslandres C, Otley A, DeBruyn J, El-Matary W, Crowley E, Sherlock M, Critch J, Ahmed N, Griffiths A, Walters T, Wine E, Canadian Children IBD Network
Outcomes and Endpoints of Postoperative Recurrence in Crohn's Disease: Systematic Review and Consensus Conference.
Hammoudi N, Sachar D, D'Haens G, Reinisch W, Kotze PG, Vermeire S, Schölmerich J, Kamm MA, Griffiths A, Panes J, Ghosh S, Siegel CA, Bemelman W, O'Morain C, Steinwurz F, Fleshner P, Mantzaris GJ, Sands B, Abreu MT, Dotan I, Turner D, Dignass A, Allez M
Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization.
Geem D, Hercules D, Pelia RS, Venkateswaran S, Griffiths A, Noe JD, Dotson JL, Snapper S, Rabizadeh S, Rosh JR, Baldassano RN, Markowitz JF, Walters TD, Ananthakrishnan A, Sharma G, Denson LA, Hyams JS, Kugathasan S
Recommendations for Broadening Eligibility Criteria in Inflammatory Bowel Disease Clinical Trials.
Siegel CA, Rai V, Outtier A, Vermeire S, Law CCW, Sands BE, Abdulhamid A, Gearry R, McGuire J, Lindsay JO, Panaccione R, Schweistein H, Dotan I, Scarallo L, Griffiths A, Dubinsky MC, International Organization for the Study of Inflammatory Bowel Disease (IOIBD)
Development and Validation of a Pediatric MRI-Based Perianal Crohn Disease (PEMPAC) Index-A Report from the ImageKids Study.
Choshen S, Turner D, Pratt LT, Precel R, Greer ML, Castro DA, Assa A, Martínez-León MI, Herman-Sucharska I, Coppenrath E, Konen O, Davila J, Bekhit E, Alsabban Z, Focht G, Gavish M, Griffiths A, Cytter-Kuint R
Endpoints for extraintestinal manifestations in inflammatory bowel disease trials: the EXTRA consensus from the International Organization for the Study of Inflammatory Bowel Diseases.
Guillo L, Abreu M, Panaccione R, Sandborn WJ, Azevedo VF, Gensler L, Moghaddam B, Ahuja V, Ali SA, Allez M, Ananthakrishnan AN, Bhattacharya A, Dubinsky M, Griffiths A, Hart A, Korelitz B, Kotze PG, Koutroubakis IE, Lakatos PL, Lindsay JO, Magro F, Mantzaris GJ, Ng SC, O'Morain C, Panés J, Parigi T, Ran Z, Rogler G, Rubin DT, Sachar DB, Siegmund B, Steinwurz F, Tysk C, Vavricka S, Verstraete SG, Brezin AP, Haemel AK, Dignass A, Sands BE, Danese S, Peyrin-Biroulet L
Clinical and Host Biological Factors Predict Colectomy Risk in Children Newly Diagnosed With Ulcerative Colitis.
Hyams JS, Brimacombe M, Haberman Y, Walters T, Gibson G, Mo A, Mack D, Griffiths A, Boyle B, LeLeiko N, Markowitz J, Rosh J, Patel A, Shah S, Baldassano R, Pfefferkorn M, Sauer C, Dailey J, Venkateswaran S, Kugathasan S, Denson LA
Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and "involved" IBD patient intestinal tissues.
McGillis L, Bronte-Tinkew DM, Dang F, Capurro M, Prashar A, Ricciuto A, Greenfield L, Lozano-Ruf A, Siddiqui I, Hsieh A, Church P, Walters T, Roth DE, Griffiths A, Philpott D, Jones NL
Ustekinumab in Paediatric Patients with Moderately to Severely Active Crohn's Disease: Pharmacokinetics, Safety, and Efficacy Results from UniStar, a Phase 1 Study.
Rosh JR, Turner D, Griffiths A, Cohen SA, Jacobstein D, Adedokun OJ, Padgett L, Terry NA, O'Brien C, Hyams JS
Developing Targeted Therapies for Rare and Common Forms of Inflammatory Bowel Disease
Principal investigators: Muise, Aleixo M
Keywords: Drug Screening; Genetics; Inflammatory Bowel Disease; Monogenic Defects; Pediatrics; Zebrafish
Elucidating the Gene-Environment Interactions that drive Autoimmune Disease among South Asian Canadians - The GEMINI Program.
Principal investigators: Gommerman, Jennifer L; Croitoru, Kenneth
Keywords: Health Geography; Immigration; Immune System; Microbiome; Nutrition; Urban Environments
Economic Evaluation of Early Intervention with anti-Tumour Necrosis Factor Alpha Medications in Children with Crohn's disease
Principal investigators: Ungar, Wendy J
Keywords: Anti-Tumour Necrosis Alpha Drugs; Child Health; Cost-Effectiveness Analysis; Crohn'S Disease; Decision Analysis; Drug Policy; Health-Related Quality Of Life; Immunomodulators; Qaly; Utilities For Pediatric Health States
NADPH oxidase function in the pathogenesis of paediatric IBD and JIA
Principal investigators: Brumell, John H
Keywords: Environmental Factors In Disease; Immune Deficiency; Inflammatory Bowel Disease; Juvenile Idiopathic Arthritis; Microbiota; Nadph Oxidase; Treatment Outcomes
Canadian Children Inflammatory Bowel Disease Network
Principal investigators: Griffiths, Anne Marie; Benchimol, Eric I; Jacobson, Kevan; Kaplan, Gilaad G; Mack, David R; Muise, Aleixo M; Otley, Anthony R; Seidman, Ernest G; Vallance, Bruce A; Walters, Thomas D; Waterhouse, Christopher C; Wine, Eytan
Keywords: Inception Cohort; Inflammatory Bowel Disease; Longitudinal Prospective; Multicenter Network; Pediatrics
Canadian Children Inflammatory Bowel Disease Network: A Joint Partnership of CIHR and the C.H.I.L.D. Foundation
Principal investigators: Griffiths, Anne Marie; Benchimol, Eric I; Jacobson, Kevan; Kaplan, Gilaad G; Mack, David R; Muise, Aleixo M; Otley, Anthony R; Seidman, Ernest G; Vallance, Bruce A; Walters, Thomas D; Waterhouse, Christopher C; Wine, Eytan
Keywords: Environment; Genetic Susceptibility; Inflammatory Bowel Disease; Microbiome; Outcomes; Pediatrics
Impact of Crohns disease-associated variants of Nod2 on cell function: role in intestinal homeostasis
Principal investigators: Van Limbergen, Johan E
Keywords: Adult Intestinal Epithelial Stem Cell; Crohn'S Disease; Inflammatory Bowel Disease; Innate Immunity; Intestinal Epithelial Cell; Long-Lived Intestinal Organoid; Nod2
Impact of Crohns disease-associated variants of Nod2 on cell function: role in intestinal homeostasis
Principal investigators: Van Limbergen, Johan E
Keywords: Adult Intestinal Epithelial Stem Cell; Crohn'S Disease; Inflammatory Bowel Disease; Innate Immunity; Intestinal Epithelial Cell; Long-Lived Intestinal Organoid; Nod2
Optimising the Phenotypic Classification of Paediatric Inflammatory Bowel Disease
Principal investigators: Sherlock, Mary
Keywords: Disease Classification; Disease Phenotype; Inflammatory Bowel Disease; Paediatric Gastroenterology
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medicine
- Pediatrics
- Pediatric Gastroenterology and Nutrition
- Biostatistics Division
- Physiology and Pharmacology
- Immunology
- Biochemistry, Microbiology & Immunology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Anthony Otley
Pediatrics
11 shared papers, latest 2025
Thomas Walters
Pediatric Gastroenterology and Nutrition
11 shared papers, latest 2025
David Mack
Biochemistry, Microbiology & Immunology
9 shared papers, latest 2022
Remo Panaccione
Physiology and Pharmacology
6 shared papers, latest 2024
Wei Xu
Biostatistics Division
5 shared papers, latest 2020
Kenneth Croitoru
Immunology
4 shared papers, latest 2020
Paul Moayyedi
Medicine
4 shared papers, latest 2020
Osvaldo Espin Garcia
Biostatistics Division
3 shared papers, latest 2020
Konstantin Shestopaloff
Biostatistics Division
3 shared papers, latest 2018
David Mack
Pediatric Gastroenterology and Nutrition
3 shared papers, latest 2018
John Kenneth Marshall
Medicine
3 shared papers, latest 2020
Amanda Ricciuto
Faculty
2 shared papers, latest 2021
Anne Griffiths
Pediatrics
2 shared papers, latest 2019
Eytan Wine
Pediatrics
2 shared papers, latest 2025
Frances Tse
Medicine
2 shared papers, latest 2019
Mary-Louise Greer
Faculty
2 shared papers, latest 2022
Brian Feagan
Department of Epidemiology and Biostatistics
1 shared papers, latest 2018
Anthony Otley
Pediatrics
1 shared papers, latest 2018
Karen Madsen
Medicine
1 shared papers, latest 2015
Jo Knight
Psychiatry
1 shared papers, latest 2016
Karen Madsen
Physiology and Pharmacology
1 shared papers, latest 2015
Tanja Gonska
Faculty
1 shared papers, latest 2010
Michael Surette
Medicine
1 shared papers, latest 2020
David Armstrong
Medicine
1 shared papers, latest 2021
Dana Philpott
Immunology
1 shared papers, latest 2021
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