Faculty profile

Jacob Vorstman

ResearcherPsychiatryUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Jacob Vorstman

Researcher

Psychiatry

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
27 publications in the last five years, latest in 2026.
Senior (last) author on 7 recent papers, a sign of leading a research group.
Principal investigator on 2 research grants (2 CIHR), most recently in 2026.
Supervised 1 trainee who won CIHR awards, most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

114

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Intellectual Disability 22q11.2 Deletion Syndrome Early Identification Autism Excitatory-Inhibitory (E/I) Balance Genetic Risk Neurodevelopmental Conditions Magnetoencephalography (Meg)Autism Early Detection

Latest papers

An n-of-1 gene-directed drug repurposing trial for an ultrarare genetic condition.
Epilepsia · 2026
Neurodevelopmental and Psychiatric Studies in Children and Adolescents With Neurofibromatosis Type I: A Comprehensive Scoping Review.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2026
Combinatorial effects of gene dosage, polygenic background and environment on complex traits.
medRxiv : the preprint server for health sciences · 2026

All 40 publications

Latest funding

Tracking the development of excitation-inhibition balance in autism and intellectual disability: a longitudinal study in a high-risk genetic population.
CIHR · 2026 · Nominated PI
$1,357,876
Leveraging multimorbidity status to predict the outcomes of children who self-harm
CIHR · 2024 · Supervisor
$120,000
Early relapse detection in youth depression: development of secondary prevention methods by multiplex digital phenotyping
CIHR · 2019 · Co-investigator
$952,424

All 6 grants and awards

40 publications.

An n-of-1 gene-directed drug repurposing trial for an ultrarare genetic condition.

Jha V, Tsetsos C, Bedford M, Costain G, Vohra S, Diaz Martinez JP, Heon E, Vorstman J, Gorodetsky C, Vincent A, Rapley J, Anderson L, Anagnostou E, Baribeau DA

Epilepsia2026

DOI: 10.1002/epi.70253 PMID: 41999155

Neurodevelopmental and Psychiatric Studies in Children and Adolescents With Neurofibromatosis Type I: A Comprehensive Scoping Review.

Chopra M, Lee TJ, Vorstman J, Parkin P, Gallagher L, Krakowski A

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics2026

DOI: 10.1002/ajmgb.70000 PMID: 41344893

Combinatorial effects of gene dosage, polygenic background and environment on complex traits.

Sacks MF, Klein M, Bigdeli TB, Kals M, Oetjens MT, Bénitière F, Johnson J, Maihofer A, Nõukas M, Francis M, Gorman B, Said I, Genovese G, Voloudakis G, Markianos K, Stein M, Gelernter J, Ledbetter DH, Nievergelt CM, Martin CL, Bourque VR, Shanta O, MacDonald JR, Thiruvahindrapuram B, Ahangari M, Srinivasan A, Guevara J, Hall JH, Haddon JE, Vingerhoets C, Linden D, van Haelst MM, van den Bree MBM, Bearden CE, Gur RE, Crowley TB, McGinn DE, Emanuel BS, Zackai EH, Swillen A, van Amelsvoort T, Vorstman J, Bassett AS, McDonald-McGinn DM, Roussos P, Aslan M, Harvey PD, Million Veteran Program, Estonian Biobank Research Team, Genes to Mental Health Network, Jacquemont S, Pyarajan S, Lehto K, Visscher PM, Sebat J

medRxiv : the preprint server for health sciences2026

DOI: 10.64898/2026.04.30.26352063 PMID: 42094142

Does genetic testing impact stigma in autism: A scoping review.

Molloy CJ, Miles A, Christoff C, Cunningham J, Reilly J, Vorstman J, Austin J, Hawke LD, Gallagher L

Journal of community genetics2026

DOI: 10.1007/s12687-025-00854-8 PMID: 41604047

Variants in DENND2B are associated with vulnerability for neurodevelopmental impairment, psychosis and catatonia.

Murthy H, Hoang N, Stark JC, Cui S, Pannia E, Tsoi CT, Harris S, Ceolin C, Verhaeghe L, Scholten S, Baribeau D, Summers J, Costain G, Selvanayagam T, Howe JL, Lewis MES, Brunet T, Rieger S, Rosenfeld JA, Craigen WJ, Burrage LC, Christie MR, Baldwin D, Wentzensen IM, Keren B, Cogne B, Isidor B, Afenjar A, Elshafie RM, Bastaki L, Alkanderi S, Myers KA, Demarest S, Angione K, Abbott M, Campeau PM, Dowling JJ, Mendoza-Londono R, Scherer SW, Deshwar AR, Vorstman J

Brain : a journal of neurology2026Senior author

DOI: 10.1093/brain/awaf273 PMID: 40717498

Neurocognitive profiles of 22q11.2 and 16p11.2 deletions and duplications.

Gur RC, Bearden CE, Jacquemont S, Swillen A, van Amelsvoort T, van den Bree M, Vorstman J, Sebat J, Ruparel K, Gallagher RS, McClellan E, White L, Crowley TB, Giunta V, Kushan L, O'Hora K, Verbesselt J, Vandensande A, Vingerhoets C, van Haelst M, Hall J, Harwood J, Chawner SJRA, Patel N, Palad K, Hong O, Guevara J, Martin CO, Jizi K, Bélanger AM, Scherer SW, Bassett AS, McDonald-McGinn DM, Gur RE

Molecular psychiatry2025

DOI: 10.1038/s41380-024-02661-y PMID: 39048645

Genomic and Developmental Models to Predict Cognitive and Adaptive Outcomes in Autistic Children.

Bourque VR, Schmilovich Z, Huguet G, England J, Okewole A, Poulain C, Renne T, Jean-Louis M, Saci Z, Zhang X, Rolland T, Labbé A, Vorstman J, Rouleau GA, Baron-Cohen S, Mottron L, Bethlehem RAI, Warrier V, Jacquemont S

JAMA pediatrics2025

DOI: 10.1001/jamapediatrics.2025.0205 PMID: 40257807

Integrative genetic analysis: cornerstone of precision psychiatry.

Vorstman J, Sebat J, Bourque VR, Jacquemont S

Molecular psychiatry2025First author

DOI: 10.1038/s41380-024-02706-2 PMID: 39215185

Clinical utility of genome sequencing in autism: illustrative examples from a genomic research study

Selvanayagam T, Hoang N, Sarikaya E, Howe J, Russell C, Iaboni A, Quirbach M, Marshall CR, Szatmari P, Anagnostou E

Journal of Medical Genetics20259 citations

DOI: 10.1136/jmg-2024-110463

Source-based morphometry reveals structural brain pattern abnormalities in 22q11.2 deletion syndrome.

Ge R, Ching CRK, Bassett AS, Kushan L, Antshel KM, van Amelsvoort T, Bakker G, Butcher NJ, Campbell LE, Chow EWC, Craig M, Crossley NA, Cunningham A, Daly E, Doherty JL, Durdle CA, Emanuel BS, Fiksinski A, Forsyth JK, Fremont W, Goodrich-Hunsaker NJ, Gudbrandsen M, Gur RE, Jalbrzikowski M, Kates WR, Lin A, Linden DEJ, McCabe KL, McDonald-McGinn D, Moss H, Murphy DG, Murphy KC, Owen MJ, Villalon-Reina JE, Repetto GM, Roalf DR, Ruparel K, Schmitt JE, Schuite-Koops S, Angkustsiri K, Sun D, Vajdi A, van den Bree M, Vorstman J, Thompson PM, Vila-Rodriguez F, Bearden CE

Human brain mapping2024

DOI: 10.1002/hbm.26553 PMID: 38224541

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Jacob Vorstman

Research

Latest papers

Latest funding

An n-of-1 gene-directed drug repurposing trial for an ultrarare genetic condition.

Neurodevelopmental and Psychiatric Studies in Children and Adolescents With Neurofibromatosis Type I: A Comprehensive Scoping Review.

Combinatorial effects of gene dosage, polygenic background and environment on complex traits.

Does genetic testing impact stigma in autism: A scoping review.

Variants in DENND2B are associated with vulnerability for neurodevelopmental impairment, psychosis and catatonia.

Neurocognitive profiles of 22q11.2 and 16p11.2 deletions and duplications.

Genomic and Developmental Models to Predict Cognitive and Adaptive Outcomes in Autistic Children.

Integrative genetic analysis: cornerstone of precision psychiatry.

Clinical utility of genome sequencing in autism: illustrative examples from a genomic research study

Source-based morphometry reveals structural brain pattern abnormalities in 22q11.2 deletion syndrome.

Tracking the development of excitation-inhibition balance in autism and intellectual disability: a longitudinal study in a high-risk genetic population.

Leveraging multimorbidity status to predict the outcomes of children who self-harm

Early relapse detection in youth depression: development of secondary prevention methods by multiplex digital phenotyping

Determining genetic and non-genetic risk for schizophrenia in a high risk group

Early prediction of developmental outcomes: a prospective study of infants with high-impact genetic risk variants

11th Biennial International 22q11.2 Conference

Frequent collaborators

Danielle Baribeau

Evdokia Anagnostou

Gregory Costain

Peter Szatmari

Peter Szatmari

Brett Trost

Meng-Chuan Lai

Ute Bartels

Fidel Vila-Rodriguez

Jehannine Austin

Roumen Milev

Sebastien Jacquemont

Leandra Desjardins

Eriskay Liston

Patricia Parkin

Paul Sandor

Ekaterina Rogaeva

Wanda Tempelaar

Paul Arnold

Jennifer Crosbie

Paul Arnold

Gustavo Turecki

Sebastien Jacquemont

Stelios Georgiades

Patrick Cossette

Alan Moses

Russell Schachar

Martin Alda

Sunita Vohra

Peter ST GEORGE-HYSLOP