This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.
Latest papers
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.
Matrix biology : journal of the International Society for Matrix Biology · 2024
Retraction Note: Glypican-3 regulates migration, adhesion and actin cytoskeleton organization in mammary tumor cells through Wnt signaling modulation.
Breast cancer research and treatment · 2024
Five siblings expand the spectrum of GPC6-related skeletal dysplasia.
American journal of medical genetics. Part A · 2023
Latest funding
- $700,525
The role of Glypican-6 in Recessive Omodysplasia
CIHR · 2015 · Nominated PI
- $614,115
The role of glypicans in the regulation of hedgehog signaling
CIHR · 2009 · Nominated PI
32 publications.
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.
Mead TJ, Bhutada S, Foulcer SJ, Peruzzi N, Nelson CM, Seifert DE, Larkin J, Tran-Lundmark K, Filmus J, Apte SS
Retraction Note: Glypican-3 regulates migration, adhesion and actin cytoskeleton organization in mammary tumor cells through Wnt signaling modulation.
Stigliano I, Puricelli L, Filmus J, Sogayar MC, Joffe EBK, Peters MAG
Five siblings expand the spectrum of GPC6-related skeletal dysplasia.
Crenshaw MM, Meyers ML, Brown K, Slegesky V, Duis J, Elias ER, Saenz M, Shi W, Filmus J, Meeks NJL
Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling.
Shi W, Filmus J
The function of glypicans in the mammalian embryo.
Filmus J
Assembling custom side chains on proteoglycans to interrogate their function in living cells.
Wang W, Han N, Xu Y, Zhao Y, Shi L, Filmus J, Li F
Glypican-6 stimulates intestinal elongation by simultaneously regulating Hedgehog and non-canonical Wnt signaling.
Shi W, Kaneiwa T, Cydzik M, Gariepy J, Filmus J
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis.
Liu T, Xia L, Yao Y, Yan C, Fan Y, Gajendran B, Yang J, Li YJ, Chen J, Filmus J, Spaner DE, Zacksenhaus E, Hao X, Ben-David Y
Novel flavagline-like compounds with potent Fli-1 inhibitory activity suppress diverse types of leukemia.
Song J, Yuan C, Yang J, Liu T, Yao Y, Xiao X, Gajendran B, Xu D, Li YJ, Wang C, Liu W, Wen M, Spaner D, Filmus J, Zacksenhaus E, Zhang Y, Hao X, Ben-David Y
Glypican-6 promotes the growth of developing long bones by stimulating Hedgehog signaling.
Capurro M, Izumikawa T, Suarez P, Shi W, Cydzik M, Kaneiwa T, Gariepy J, Bonafe L, Filmus J
The role of Glypican-6 in Recessive Omodysplasia
Principal investigators: Filmus, Jorge E
Keywords: Animal Models; Glypicans; Hedgehog Signaling; Proteoglycans; Recessive Omodysplasia
The role of glypicans in the regulation of hedgehog signaling
Principal investigators: Filmus, Jorge E
Keywords: Glypicans; Hedgehog; Ovarian Cancer; Rhabdomyosarcoma
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Jean Gariepy and Jorge Filmus: 2 shared papers
- Eldad Zacksenhaus and Jorge Filmus: 2 shared papers
- David Spaner and Eldad Zacksenhaus: 1 shared paper
- David Spaner and Jorge Filmus: 1 shared paper
- Jorge Filmus and Jonathan Rast: 1 shared paper
- Department of Medical Biophysics
- Cellular and Molecular Biology
- Cancer and Cell Biology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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