Faculty profile

Lorne Zinman

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ProfessorDepartment of MedicineUniversity of Toronto

Lorne Zinman

Professor

Department of Medicine

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
93 publications in the last five years, latest in 2026.
Senior (last) author on 8 recent papers, a sign of leading a research group.
Principal investigator on 1 research grant (1 CIHR), most recently in 2015.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

272

Publications

16,029

Citations

227

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Cardiac Care Cognitive Complications Genomics Interdisciplinary Care Knowledge Translation Nutritional Interventions Rare Disease Rehabilitation

Latest papers

Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis.
Nature genetics · 2026
Multi-omics analyses identify potential epigenetic loci associated with survival in amyotrophic lateral sclerosis across diverse populations.
EBioMedicine · 2026
Neuropsychiatric Symptom Clusters and Their Association With Brain Structure in Alzheimer Disease.
The Journal of clinical psychiatry · 2026

All 272 publications

Latest funding

Mapping patterns of brain metabolic alterations in neurodegenerative diseases using ultra-high-field MRSI
CIHR · 2025 · Co-investigator
$883,575
NMD4C: the neuromuscular network for Canada
CIHR · 2023 · Co-investigator
$1,000,000
Real-World Evidence for Canadian Neuromuscular Disease: Establishing a Framework for National Integration of Patient Reported Outcomes, Clinical Registry Data, Healthcare Utilization and Healthcare Associated Costs
CIHR · 2023 · Co-investigator
$1,597,256

All 9 grants and awards

From the 150 most recent of 272 publications.

Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis.

Hop PJ, Kooyman M, Kenna BJ, Zwamborn RAJ, van Eijk KR, Wang Y, van Dijk CH, Bekema E, van Rheenen W, Beele P, van Vugt JJFA, Project MinE ALS sequencing Consortium, NYGC ALS Consortium, FALS sequencing Consortium, GTAC Consortium, Khleifat AA, Iacoangeli A, Cooper-Knock J, Smith BN, Topp S, van der Kooi AJ, Fominykh V, Drory V, Lerner Y, Shovman Y, Rowe DB, Williams KL, McLaughlin RL, Hurt J, Huang Y, Chen CY, Tsai E, Runz H, Aronica E, Groen EJN, van Es MA, Pasterkamp RJ, Farhan SMK, Garton FC, McRae AF, McCombe PA, Henderson RD, Fan D, Šlachtová L, Høyer H, Nishimura AL, Cauchi RJ, Brylev L, Rogelj B, Koritnik B, Zidar J, Salas T, Mora Pardina JS, Gotkine M, Povedano M, Corcia P, Vourc'h P, Couratier P, Weber M, Kiernan MC, Pamphlett R, Blair IP, de Carvalho M, Başak NA, Ingre C, Andersen PM, Zinman L, Rogaeva E, MacKenzie IR, Dupre N, Rouleau GA, Traynor BJ, Ticozzi N, Chiò A, Silani V, Hardiman O, Phatnani H, Harms MB, Dalgard CL, Glass JD, Landers JE, Van Damme P, Morrison KE, Shaw PJ, Shaw CE, Al-Chalabi A, van den Berg LH, Kenna KP, Veldink JH

Nature genetics202613 citationsOpen Access

DOI: 10.1038/s41588-026-02535-9 PMID: 41917433

Multi-omics analyses identify potential epigenetic loci associated with survival in amyotrophic lateral sclerosis across diverse populations.

Gu Y, Chen Y, Tang X, Guo J, Hu J, Yang W, Li J, Chen X, Fan D, Chen GB, He J, Ren Y, Dong Y, Sato C, Chen Y, Zinman L, Rogaeva E, Zhang M

EBioMedicine20261 citationsOpen Access

DOI: 10.1016/j.ebiom.2025.106071 PMID: 41380476

Neuropsychiatric Symptom Clusters and Their Association With Brain Structure in Alzheimer Disease.

Kapustin D, Rashidi-Ranjbar N, Wang W, Binns MA, McLaughlin PM, Abrahao A, Grimes D, Lang A, Marras C, Masellis M, Orange JB, Rajji TK, Roberts A, Saposnik G, Swartz RH, Tang-Wai DF, Tartaglia MC, Troyer A, Zinman L, Fischer CE, Kumar S

The Journal of clinical psychiatry20261 citations

DOI: 10.4088/jcp.25m16192 PMID: 41871235

Phase 3b Extension Study MT‐1186‐A04 to Evaluate the Continued Efficacy and Safety of Edaravone Oral Suspension for Up to an Additional 48 Weeks in Patients With Amyotrophic Lateral Sclerosis

Genge A, Rothstein J, De Silva S, Zinman L, Chum M, Chiò A, Sobue G, Aoki M, Yoshino H, Doyu M

Muscle and Nerve20261 citationsOpen Access

DOI: 10.1002/mus.70120

The Muscle Cramp Impact Index: A Patient-Centered Scale for the Assessment of Muscle Cramps.

Katzberg HD, Bril V, Zinman L, Abrahao A, Cherney D, Shah H, Mendoza MG, Alfaidi N, Alnajjar S, Barnett-Tapia C

Neurology2026

DOI: 10.1212/wnl.0000000000214835 PMID: 41955555

Depressive symptoms, but not OSA severity, are associated with general fatigue in myasthenia gravis.

Tchoudnovski D, Yang D, Ntale I, Xie H, Zinman L, Izenberg A, Choi S, Abrahao A, Katzberg H, Boulos MI

Sleep medicine2026

DOI: 10.1016/j.sleep.2026.108970 PMID: 42070450

Association between statin use and survival in patients with ALS: A propensity score-matched analysis

Saldanha-Castro P, Vyas MV, Jain D, Santos-Neto D, Mirian A, Consortium TPRO-AACT, Zinman L, Abrahao A

Journal of the Neurological Sciences2026Senior author

DOI: 10.1016/j.jns.2026.125916

Understanding patients' experiences and needs around decision-making for bulbar symptom management at a multidisciplinary ALS clinic.

Huynh A, Cranley L, Barnett-Tapia C, Abrahao A, Zinman L, Yunusova Y

Disability and rehabilitation2026

DOI: 10.1080/09638288.2026.2693395 PMID: 42385017

“Straddling two worlds”: complexities of spousal caregiving in amyotrophic lateral sclerosis during younger middle age

Andrea Parks, Lesley Gotlib Conn, Agessandro Abrahão, Lorne H. Zinman, Joanna E. M. Sale

BMC Palliative Care2026Open Access

DOI: 10.1186/s12904-026-02230-w PMID: 42436431

Age and life stage in the experience of amyotrophic lateral sclerosis: a scoping review.

Parks ASE, Gotlib Conn L, Amog K, Bodmer NS, King JW, McLaren AMR, Reid M, Kishibe T, Abrahao A, Zinman L, Sale JEM

Amyotrophic lateral sclerosis & frontotemporal degeneration2026

DOI: 10.1080/21678421.2025.2515914 PMID: 40511793

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Lorne Zinman

Research

Latest papers

Latest funding

Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis.

Multi-omics analyses identify potential epigenetic loci associated with survival in amyotrophic lateral sclerosis across diverse populations.

Neuropsychiatric Symptom Clusters and Their Association With Brain Structure in Alzheimer Disease.

Phase 3b Extension Study MT‐1186‐A04 to Evaluate the Continued Efficacy and Safety of Edaravone Oral Suspension for Up to an Additional 48 Weeks in Patients With Amyotrophic Lateral Sclerosis

The Muscle Cramp Impact Index: A Patient-Centered Scale for the Assessment of Muscle Cramps.

Depressive symptoms, but not OSA severity, are associated with general fatigue in myasthenia gravis.

Association between statin use and survival in patients with ALS: A propensity score-matched analysis

Understanding patients' experiences and needs around decision-making for bulbar symptom management at a multidisciplinary ALS clinic.

“Straddling two worlds”: complexities of spousal caregiving in amyotrophic lateral sclerosis during younger middle age

Age and life stage in the experience of amyotrophic lateral sclerosis: a scoping review.

Frequent collaborators

Ekaterina Rogaeva

Angela Genge

Yana Yunusova

Sandra Black

Sanjay Kalra

Lawrence Korngut

Elizabeth Finger

Mario Masellis

Richard Swartz

Janice Robertson

Malcolm Binns

John Turnbull

Connie Marras

Andrew Frank

Michael Borrie

Corinne Fischer

David Grimes

Gustavo Saposnik

Angela Roberts

Tarek Rajji

J.B. Orange

Morris Freedman

Christopher Hudson

Joel Ramirez

Chris Hudson

Sean Symons

Carolina Barnett-Tapia

Leanne Casaubon

Daniel Kapustin

David Tang-Wai

Aaron Izenberg

Anu Tandon

Nicolae Petrescu

Carmela Tartaglia

David Fam

Brian Murray

Andrew Micieli

Melanie DeHaan

Wendy Hatch

Hernan Gonorazky