This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells.
Nature communications · 2021
Omnipolarity applied to equi-spaced electrode array for ventricular tachycardia substrate mapping.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2019
Latest funding
- $990,676
Scaled biomanufacturing of mature stem cell-derived cardiomyocytes via electrical stimulation
CIHR · 2026 · Nominated PI
- $140,000
Exploring the health system and market adoption of novel cardiac therapies using human pluripotent stem cell-derived cardiomyocytes (hPSC-CM)
CIHR · 2025 · Supervisor
- $45,000
Development of a synthetic safety switch to control graft related arrhythmias following human stem cell-derived cardiomyocyte transplantation post-myocardial infarction
CIHR · 2022 · Supervisor
2 publications.
Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells.
Funakoshi S, Fernandes I, Mastikhina O, Wilkinson D, Tran T, Dhahri W, Mazine A, Yang D, Burnett B, Lee J, Protze S, Bader GD, Nunes SS, Laflamme M, Keller G
Omnipolarity applied to equi-spaced electrode array for ventricular tachycardia substrate mapping.
Porta-Sánchez A, Magtibay K, Nayyar S, Bhaskaran A, Lai PFH, Massé S, Labos C, Qiang B, Romagnuolo R, Masoudpour H, Biswas L, Ghugre N, Laflamme M, Deno DC, Nanthakumar K
Scaled biomanufacturing of mature stem cell-derived cardiomyocytes via electrical stimulation
Principal investigators: Laflamme, Michael A
Keywords: Biomanufacturing; Bioreactors; Cell Transplantation; Electrical Stimulation; Human Pluripotent Stem Cell-Derived Cardiomyocytes; Myocardial Infarction
Exploring the health system and market adoption of novel cardiac therapies using human pluripotent stem cell-derived cardiomyocytes (hPSC-CM)
Principal investigators: Francis, Troy A
Keywords: Early Health Technology Assessment; Health Economics; Heart Failure; Pluripotent Stem Cells; Regenerative Medicine; Return On Investment; Social Network Analysis; Stakeholder Analysis
Development of a synthetic safety switch to control graft related arrhythmias following human stem cell-derived cardiomyocyte transplantation post-myocardial infarction
Principal investigators: Alibhai, Faisal J
Keywords: Cardiovascular Disease; Cell Transplanation; Electrophysiology; Myocardial Infarction; Stem Cells; Synthetic Biology
Enabling novel cardiac therapies with pluripotent stem cells
Principal investigators: Laflamme, Michael
Gene-edited hPSC-CMs as a novel strategy to eliminate graft-related arrhythmia
Principal investigators: Al-attar, Rasha
Keywords: Cell-Cell Communication; Electrical Integration; Genome Engineering; Heart Failure; Myocardial Infarction; Pluripotent Stem Cell Derived-Cardiomyocytes; Post-Translational Modification; Regenerative Medicine; Stem Cell Differentiation; Stem Cell Transplantation
Enabling novel cardiac therapies with pluripotent stem cells
Principal investigators: Laflamme, Michael
Keywords: Cardiac regeneration Pluripotent stem cells Cell manufacturing Heart failure Synthetic biology Tissue engineering Biomedical imaging 3D bioprinting Mathematical modeling Health technology assessment Bioethics
Imaging microvascular dysfunction: a new paradigm for early detection of heart failure
Principal investigators: Cheng, Hai-Ling M
Keywords: Diabetes; Echocardiography; Heart Failure; Magnetic Resonance Imaging; Microvascular Dysfunction; Photoacoustics; Preserved Ejection Fraction
Canada Research Chairs - Tier 1
Principal investigators: Laflamme, Michael A
Keywords: Crc
Optimization of cell culture media and substrates to mature pluripotent stem cell-derived cardiomyoctyes for improved cardiac cell therapy
Principal investigators: Simmons, Craig A
Keywords: Biomaterials; Cardiomyocytes; Cell Culture; Neural Network; Screening
Generation of Human Pluripotent Stem Cell-Derived Left Ventricular Cardiomyocytes for the Treatment of Hypoplastic Left Heart Syndrome
Principal investigators: Mazine, Amine
Keywords: Cardiac Regeneration; Cardiac Surgery; Cell Signaling; Cell Therapy; Congenital Heart Disease; Developmental Biology; Preclinical Models Of Cardiac Disease; Regenerative Medicine; Stem Cell Differentiation; Stem Cells
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Gordon Keller and Kumaraswamy Nanthakumar: 5 shared papers
- Gordon Keller and Stephanie Protze: 5 shared papers
- Kumaraswamy Nanthakumar and Stephanie Protze: 2 shared papers
- Gordon Keller and Michael Laflamme: 1 shared paper
- Kumaraswamy Nanthakumar and Michael Laflamme: 1 shared paper
- Kumaraswamy Nanthakumar and Nilesh Ghugre: 1 shared paper
- Stephanie Protze and Michael Laflamme: 1 shared paper
- Michael Laflamme and Nilesh Ghugre: 1 shared paper
- Department of Medical Biophysics
- Medical biotechnology
- Medicine/Cardiology
- McEwen Stem Cell Institute
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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