This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Therapeutic radiation drives leptomeningeal dissemination of medulloblastoma through an innate immune process.
Developmental cell · 2025
Exploring the merits of research performance measures that comply with the San Francisco Declaration on Research Assessment and strategies to overcome barriers of adoption: qualitative interviews with administrators and researchers.
Health research policy and systems · 2023
A feasibility study of photoacoustic imaging of ex vivo endoscopic mucosal resection tissues from Barrett's esophagus patients.
Endoscopy international open · 2017
Latest funding
- $1,124,550
Using Intravital Imaging to Understand how Acute Myeloid Leukemia Remodels the Bone Marrow Microenvironment In Vivo and how this Impacts Therapeutic Response
CIHR · 2026 · Nominated PI
- $612,000
Understanding the Interaction of Acute Myeloid Leukemia with the Bone Marrow Microenvironment: Elucidating New Therapeutic Targets Through In Vivo Imaging
CIHR · 2020 · Nominated PI
- $2,922,300
The Canadian F.I.G.H.T. (Fluorescence Image-Guided Help in Treating) Breast Cancer Surgical Trial
CIHR · 2016 · Nominated PI
7 publications.
Therapeutic radiation drives leptomeningeal dissemination of medulloblastoma through an innate immune process.
Nör C, Kharas K, Rasnitsyn A, Vladoiu MC, Cho NW, Young JS, Nör F, Mankahla N, Haapasalo J, Nordfors K, Rapic S, Skowron P, Suárez RA, Bahcheli AT, Ocsenas O, Chen X, Bahrampour S, Momin A, Sundaresan L, Ong W, Hendrikse LD, Abeysundara N, Juraschka K, Ly M, Pallota JG, Douglas T, Huang N, Wang H, Mak E, Qin L, Liu J, Shen L, Luu B, Manno A, Kumar SA, Donovan LK, Fong V, Richman C, Daniels C, Garzia L, Rich JN, Hawkins C, Wu X, DaCosta R, Reimand J, Huang X, Ramaswamy V, Raleigh DR, Taylor MD
Exploring the merits of research performance measures that comply with the San Francisco Declaration on Research Assessment and strategies to overcome barriers of adoption: qualitative interviews with administrators and researchers.
Boury H, Albert M, Chen RHC, Chow JCL, DaCosta R, Hoffman MM, Keshavarz B, Kontos P, McAndrews MP, Protze S, Gagliardi AR
A feasibility study of photoacoustic imaging of ex vivo endoscopic mucosal resection tissues from Barrett's esophagus patients.
Lim L, Streutker CJ, Marcon N, Cirocco M, Lao A, Iakovlev VV, DaCosta R, Wilson BC
A prototype hand-held tri-modal instrument for in vivo ultrasound, photoacoustic, and fluorescence imaging.
Kang J, Chang JH, Wilson BC, Veilleux I, Bai Y, DaCosta R, Kim K, Ha S, Lee JG, Kim JS, Lee SG, Kim SM, Lee HJ, Ahn YB, Han S, Yoo Y, Song TK
A multifunctional polymeric nanotheranostic system delivers doxorubicin and imaging agents across the blood-brain barrier targeting brain metastases of breast cancer.
Li J, Cai P, Shalviri A, Henderson JT, He C, Foltz WD, Prasad P, Brodersen PM, Chen Y, DaCosta R, Rauth AM, Wu XY
Advanced imaging technologies for the detection of dysplasia and early cancer in barrett esophagus.
Espino A, Cirocco M, Dacosta R, Marcon N
Serum-free differentiation of functional human coronary-like vascular smooth muscle cells from embryonic stem cells.
El-Mounayri O, Mihic A, Shikatani EA, Gagliardi M, Steinbach SK, Dubois N, Dacosta R, Li RK, Keller G, Husain M
Using Intravital Imaging to Understand how Acute Myeloid Leukemia Remodels the Bone Marrow Microenvironment In Vivo and how this Impacts Therapeutic Response
Principal investigators: Dacosta, Ralph S
Keywords: Acute Myeloid Leukemia; Bone Marrow; Fluorescence Microscopy; Hypoxia; Immune Cells; Intravital Optical Imaging; Leukemia Treatments; Microvasculature; Transcriptomics; Tumor Microenvironment
Understanding the Interaction of Acute Myeloid Leukemia with the Bone Marrow Microenvironment: Elucidating New Therapeutic Targets Through In Vivo Imaging
Principal investigators: Dacosta, Ralph S; Minden, Mark D
Keywords: Acute Myeloid Leukemia; Bone Marrow; Cxcr4; Fluorescent Microscopy; Hypoxia; Hypoxia Activated Drugs; Intravital Imaging; Leukemia; Rna Sequencing; Tumour Microenvironment
The Canadian F.I.G.H.T. (Fluorescence Image-Guided Help in Treating) Breast Cancer Surgical Trial
Principal investigators: Dacosta, Ralph S
Keywords: Breast Cancer Surgery; Breast Conservative Surgery; Breast Pathology; Cancer Imaging; Fluorescence Contrast Agents; Fluorescence Image-Guided Surgery; Intraoperative Margin Assessment; Medical Devices; Optical Imaging; Surgical Re-Excision
The FL.I.G.H.T (Fluorescence Image-Guided Healing Trial) for Diabetic Foot Ulcers: A Single Centre Phase II Trial
Principal investigators: Dacosta, Ralph S
Keywords: Bacteria; Diabetes Wound Complications; Diabetic Foot Ulcers; Fluorescence Imaging; Health Economics; Microbiology; Quality Of Life; Wound Debridement; Wound Healing; Wound Sampling
The Canadian F.I.G.H.T. (Fluorescence Image-Guided Help in Treating) Breast Cancer Surgical Trial
Principal investigators: Dacosta, Ralph S
Keywords: Breast Cancer Surgery; Breast Conservative Surgery; Breast Pathology; Cancer Imaging; Fluorescence Contrast Agents; Fluorescence Guided Surgery; Intraoperative Margin Assessment; Medical Device; Optical Imaging; Surgery
Portable Intraoperative Fluorescence Imaging for Real-time Margin Assessment and Guidance During Breast Cancer Surgery
Principal investigators: Dacosta, Ralph S
Keywords: Breast Cancer Surgery; Breast Conservative Surgery; Breast Pathology; Cancer Imaging; Fluorescence Contrast Agents; Fluorescence Guided Surgery; Margin Assessment; Medical Device; Optical Imaging; Surgery
Developing Preclinical Optical Imaging Tools for Studying Vasculature, Microenvironment, and Radiation Response of Solid Tumours In Vivo.
Principal investigators: Dacosta, Ralph S
Keywords: Genomic And Proteomic Profiling; Hypoxia And Oxygenation; Intravital Optical Molecular Imaging; Phosphorescence Lifetime Imaging; Photoacoustic Microscopic Imaging; Radiation Response; Spatio-Temporal Dynamics; Tumor Cell Death And Vascular Damage; Xenograft And Orthotopic Tumor Models
Optical coherence tomography for assessment of early radiobiological response in-vivo
Principal investigators: Vitkin, I. Alex
Keywords: Animal Tumour Models; Biomedical Optics; Cancer; Medical Imaging; Optical Coherence Tomography; Radiation Biophysics; Radiation Therapy; Radiobiology; Spectroscopy And Speckle Analysis; Window Chamber
Development of PRODIGI, a Handheld Optical Imaging Technology for Real-time Intraoperative-guidance of Breast Tumour Resection
Principal investigators: Dacosta, Ralph S
Keywords: Breast Cancer Surgery; Brest Cancer Detection And Diagnosis; Fluorescence Imaging; Image-Gudied Surgery; Intraoperative Imaging Technologies; Optical Image-Guided Surgery Of Breast Cancer; Optical Imaging Devices; Tumor Margins
Probing the Temporal Dynamics of Tumor Cell Kill and Vascular Damage in Radiation Therapy using Optical Molecular Imaging Techniques
Principal investigators: Dacosta, Ralph S
Keywords: Hypoxia; Optical Molecular Imaging; Radiation Response; Temporal Dynamics; Tumor Cell Death; Vascular Damage
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medical Biophysics
- Department of Laboratory Medicine and Pathobiology
- Medicine
- Social & Behavioural Health Sciences Division
- Cardiovascular Surgery
- Developmental Stem Cell Biology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Gordon Keller
Medical Biophysics
1 shared papers, latest 2013
Cynthia Hawkins
Department of Laboratory Medicine and Pathobiology
1 shared papers, latest 2025
Mansoor Husain
Medicine
1 shared papers, latest 2013
Ren-Ke Li
Cardiovascular Surgery
1 shared papers, latest 2013
Pia Kontos
Social & Behavioural Health Sciences Division
1 shared papers, latest 2023
Xi Huang
Faculty
1 shared papers, latest 2025
Vijay Ramaswamy
Developmental Stem Cell Biology
1 shared papers, latest 2025
Livia Garzia
Faculty
1 shared papers, latest 2025
Stephanie Protze
Faculty
1 shared papers, latest 2023
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