Faculty profile

Rita Kandel

Back to faculty

ProfessorDepartment of Laboratory Medicine and PathobiologyUniversity of Toronto

Rita Kandel

Professor

Department of Laboratory Medicine and Pathobiology

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

ORCID

Supervision signals

Professors usually supervise graduate students in their department's programs.
6 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 11 research grants (6 CIHR, 5 NSERC), most recently in 2022.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

University Profile Personal Website Search on Google Scholar iDORCID

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Tissue Engineering Regenerative Medicine Stem Cells Intervertebral Disc 3d Printing (Additive Manufacturing)Arthritis Cartilage Chondrocytes

Latest papers

A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section.
JOR spine · 2026
Reversion of passaged nucleus pulposus cells to notochordal-type cells by FoxA2 upregulation.
NPJ Regenerative medicine · 2025 · senior author
Senescent response in inner annulus fibrosus cells in response to TNFα, H2O2, and TNFα-induced nucleus pulposus senescent secretome.
PloS one · 2024 · senior author

All 37 publications

Latest funding

Melt electrowrite system for biofabrication of complex engineered tissues
NSERC · 2023 · Co-investigator
$150,000
An intervertebral disc replacement: a regenerative medicine approach
CIHR · 2022 · Nominated PI
$1,170,450
Optimization of Osteochondral-like Implants for Joint Repair
NSERC · 2019 · Principal investigator
$124,704

All 18 grants and awards

37 publications.

A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section.

Bhadouria N, Gawri R, Graziani G, Anderson DE, Chee AV, Dahia CL, Diwan A, Giers MB, Illien-Junger S, Kirilusha A, Nuckley DJ, Rosenzweig DH, Séguin C, Sheyn D, Teixeira GQ, Alini M, Ito K, Mauck RL, Sakai D, Bailey J, Fields AJ, Grad S, Gullbrand SE, Holguin N, Kandel R, Li Z, Li J, Martin JT, Mwale F, O'Connell GD, Purmessur D, Vo N, Zehra U, Chahine NO, Haglund L, Hoyland JA, Le Maitre CL, Lotz JC, Risbud MV, Smith LJ, Tang S, Iatridis JC, Wuertz-Kozak K, Samartzis D

JOR spine2026

DOI: 10.1002/jsp2.70180 PMID: 41982788

Reversion of passaged nucleus pulposus cells to notochordal-type cells by FoxA2 upregulation.

Ashraf S, Montgomery-Song A, Thom C, Davison Kotler E, Chan B, Zelinka A, Santerre P, Kandel R

NPJ Regenerative medicine2025Senior author

DOI: 10.1038/s41536-025-00437-8 PMID: 41173930

Senescent response in inner annulus fibrosus cells in response to TNFα, H2O2, and TNFα-induced nucleus pulposus senescent secretome.

Montgomery-Song A, Ashraf S, Santerre P, Kandel R

PloS one2024Senior author

DOI: 10.1371/journal.pone.0280101 PMID: 38181003

Education of the clinical embryology laboratory professional: development of a novel program delivered in a laboratory medicine department.

Shapiro H, Brown TJ, Chronis-Brown P, Hamilton GS, Bentley DC, Kandel R, Gotlieb AI

F&S reports2023

DOI: 10.1016/j.xfre.2023.03.001 PMID: 37719097

Adseverin, an actin-binding protein, modulates hypertrophic chondrocyte differentiation and osteoarthritis progression.

Chan B, Glogauer M, Wang Y, Wrana J, Chan K, Beier F, Bali S, Hinz B, Parreno J, Ashraf S, Kandel R

Science advances2023Senior author

DOI: 10.1126/sciadv.adf1130 PMID: 37540756

Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies.

Gajic-Veljanoski O, Li C, Schaink AK, Guo J, Shehata N, Charames GS, de Vrijer B, Clarke G, Pechlivanoglou P, Okun N, Kandel R, Dooley J, Higgins C, Ng V, Sikich N

Transfusion2022

DOI: 10.1111/trf.16826 PMID: 35170037

Induced senescence of healthy nucleus pulposus cells is mediated by paracrine signaling from TNF-α-activated cells.

Ashraf S, Santerre P, Kandel R

FASEB journal : official publication of the Federation of American Societies for Experimental Biology2021Senior author

DOI: 10.1096/fj.202002201r PMID: 34403508

Comparative evaluation of four hydrogen peroxide-based systems to decontaminate N95 respirators.

Clark S, Ng H, Wu G, Jain D, Bassi G, Kandel R, Mazzulli T

Antimicrobial stewardship & healthcare epidemiology : ASHE2021

DOI: 10.1017/ash.2021.183 PMID: 36168470

Inorganic polyphosphates stimulates matrix production in human annulus fibrosus cells.

Wang X, Gawri R, Lei C, Lee J, Sowa G, Kandel R, Vo N

JOR spine2021

DOI: 10.1002/jsp2.1143 PMID: 34337332

American Society for Bone and Mineral Research-Orthopaedic Research Society Joint Task Force Report on Cell-Based Therapies - Secondary Publication.

O'Keefe RJ, Tuan RS, Lane NE, Awad HA, Barry F, Bunnell BA, Colnot C, Drake MT, Drissi H, Dyment NA, Fortier LA, Guldberg RE, Kandel R, Little DG, Marshall MF, Mao JJ, Nakamura N, Proffen BL, Rodeo SA, Rosen V, Thomopoulos S, Schwarz EM, Serra R

Journal of orthopaedic research : official publication of the Orthopaedic Research Society2020

DOI: 10.1002/jor.24485 PMID: 31994782

Melt electrowrite system for biofabrication of complex engineered tissues

Co-investigatorNSERC2023Research Tools and Instruments

Principal investigators: Simmons, Craig

$150,000

An intervertebral disc replacement: a regenerative medicine approach

Nominated PICIHR2022Project Grant

Principal investigators: Kandel, Rita A

Keywords: Bone Substitute; Crispr/Cas9; Intervertebral Disc; Perfusion Bioreactor; Scaffolds; Tissue Engineering

$1,170,450

Optimization of Osteochondral-like Implants for Joint Repair

Principal investigatorNSERC2019Idea to Innovation

Principal investigators: Kandel, Rita

$124,704

Bioengineering a finger joint replacement

Nominated PICIHR2018Project Grant

Principal investigators: Kandel, Rita A; Toyserkani, Ehsan

Keywords: 3d Printing (Additive Manufacturing); Arthritis; Cartilage; Chondrocytes; Joint Replacements; Regenerative Medicine; Stem Cells; Tissue Engineering

$688,501

Biological Finger Joint Replacement

Principal investigatorNSERC2018Collaborative Health Research Projects

Principal investigators: Kandel, Rita

$299,503

Biological Finger Joint Replacement

Nominated PICIHR2017Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Kandel, Rita A; Schubert, Carl; Toyserkani, Ehsan

Keywords: 3d Printing (Additive Manufacturing); Arthritis; Cartilage; Chondrocytes; Finger Joints; Joint Replacements; Regenerative Medicine; Stem Cells; Tissue Engineering

$299,503

Advanced platform to characterize the mechanical and structural properties of natural and engineered soft biomaterials

Co-investigatorNSERC2016Research Tools and Instruments

Principal investigators: Simmons, Craig

$149,911

Substrate stiffness and the role of actin in regulating chondrocyte dedifferentiation

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Kandel, Rita

$264,000

Equipment for development of a novel and customized additive manufacturing (3D printing) workstation for producing heterogeneous soft tissues/implants, extracorporeal devices and prostheses

Co-investigatorNSERC2016Research Tools and Instruments

Principal investigators: Toyserkani, Ehsan

$148,599

Substrate stiffness and the role of actin in regulating the dedifferentiated articular chondrocyte phenotype

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: Kandel, Rita

$30,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

Something wrong or missing on this profile? Suggest a correction

Rita Kandel

Research

Latest papers

Latest funding

A Decade of Leadership and Impact: Celebrating 10&#x2009;Years of the ORS Spine Section.

Reversion of passaged nucleus pulposus cells to notochordal-type cells by FoxA2 upregulation.

Senescent response in inner annulus fibrosus cells in response to TNF&#x3b1;, H2O2, and TNF&#x3b1;-induced nucleus pulposus senescent secretome.

Education of the clinical embryology laboratory professional: development of a novel program delivered in a laboratory medicine department.

Adseverin, an actin-binding protein, modulates hypertrophic chondrocyte differentiation and osteoarthritis progression.

Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies.

Induced senescence of healthy nucleus pulposus cells is mediated by paracrine signaling from TNF-&#x3b1;-activated cells.

Comparative evaluation of four hydrogen peroxide-based systems to decontaminate N95 respirators.

Inorganic polyphosphates stimulates matrix production in human annulus fibrosus cells.

American Society for Bone and Mineral Research-Orthopaedic Research Society Joint Task Force Report on Cell-Based Therapies - Secondary Publication.

Melt electrowrite system for biofabrication of complex engineered tissues

An intervertebral disc replacement: a regenerative medicine approach

Optimization of Osteochondral-like Implants for Joint Repair

Bioengineering a finger joint replacement

Biological Finger Joint Replacement

Biological Finger Joint Replacement

Advanced platform to characterize the mechanical and structural properties of natural and engineered soft biomaterials

Substrate stiffness and the role of actin in regulating chondrocyte dedifferentiation

Equipment for development of a novel and customized additive manufacturing (3D printing) workstation for producing heterogeneous soft tissues/implants, extracorporeal devices and prostheses

Substrate stiffness and the role of actin in regulating the dedifferentiated articular chondrocyte phenotype

Frequent collaborators

Paul Santerre

Jean-Michel Caudrelier

Shailendra Verma

Joel Werier

Xiaomei Yao

Michelle Ghert

Michael Glogauer

Jeffrey Wrana

Barbra De Vrijer

Lisbet Haglund

Fackson Mwale

Petros Pechlivanoglou

Fackson Mwale

George Tomlinson

Abha Gupta

Tony Mazzulli

Dongsheng Tu

Vivian Ng

Rahul Gawri

Jagdish Butany

Frank Beier

Heather Shapiro

Barry Rubin

Katherine Zukotynski

Marc Grynpas

Boris Hinz

A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section.

Senescent response in inner annulus fibrosus cells in response to TNFα, H2O2, and TNFα-induced nucleus pulposus senescent secretome.

Induced senescence of healthy nucleus pulposus cells is mediated by paracrine signaling from TNF-α-activated cells.