This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Intracellular IL-23R is necessary for mitotic spindle formation and viability in AML.
Leukemia · 2026
Hematopoietic stem cell aging promotes TET2 clonal hematopoiesis.
Research square · 2026
Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance.
Cell stem cell · 2018
Latest funding
- $1,124,550
Using Intravital Imaging to Understand how Acute Myeloid Leukemia Remodels the Bone Marrow Microenvironment In Vivo and how this Impacts Therapeutic Response
CIHR · 2026 · Co-investigator
GLP-1 Receptor Agonists as a Preventive Strategy for Clonal Hematopoiesis-Driven Hematologic Cancers
CIHR · 2025 · Principal investigator
- $1,591,200
Discovery of sex-dimorphic leukemia-protective programs embedded in human hematopoietic stem cells
CIHR · 2025 · Co-investigator
8 publications.
Intracellular IL-23R is necessary for mitotic spindle formation and viability in AML.
Duong N, Khan DH, Thomas GE, Feng Y, Hurren R, Lee JB, St-Germain J, Drimmer L, Yan Y, Zhang LX, Fang KK, Ling D, Ma ML, MacLean N, Gronda M, Rondeau V, Brown BD, Matellán L, Jones CL, Chang H, Arruda A, Xie S, Pelletier L, Minden MD, Zhang L, Kornblau SM, Raught B, Jacobs K, Jacobs MG, Goede D, Spadavecchio V, Schimmer AD
Hematopoietic stem cell aging promotes TET2 clonal hematopoiesis.
De Dominici M, Naddaf L, Varesi A, Goodspeed A, Hoag B, Zaberezhnyy V, Menzel J, Liu Y, Xie S, Li S, DeGregori J
Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance.
Golan K, Kumari A, Kollet O, Khatib-Massalha E, Subramaniam MD, Ferreira ZS, Avemaria F, Rzeszotek S, García-García A, Xie S, Flores-Figueroa E, Gur-Cohen S, Itkin T, Ludin-Tal A, Massalha H, Bernshtein B, Ciechanowicz AK, Brandis A, Mehlman T, Bhattacharya S, Bertagna M, Cheng H, Petrovich-Kopitman E, Janus T, Kaushansky N, Cheng T, Sagi I, Ratajczak MZ, Méndez-Ferrer S, Dick JE, Markus RP, Lapidot T
Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell-mediated TNFα signaling.
Wang W, Fujii H, Kim HJ, Hermans K, Usenko T, Xie S, Luo ZJ, Ma J, Celso CL, Dick JE, Schroeder T, Krueger J, Wall D, Egeler RM, Zandstra PW
SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress.
Zipin-Roitman A, Aqaqe N, Yassin M, Biechonski S, Amar M, van Delft MF, Gan OI, McDermott SP, Buzina A, Ketela T, Shlush L, Xie S, Voisin V, Moffat J, Minden MD, Dick JE, Milyavsky M
AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress.
Sriskanthadevan S, Jeyaraju DV, Chung TE, Prabha S, Xu W, Skrtic M, Jhas B, Hurren R, Gronda M, Wang X, Jitkova Y, Sukhai MA, Lin FH, Maclean N, Laister R, Goard CA, Mullen PJ, Xie S, Penn LZ, Rogers IM, Dick JE, Minden MD, Schimmer AD
CDK6 levels regulate quiescence exit in human hematopoietic stem cells.
Laurenti E, Frelin C, Xie S, Ferrari R, Dunant CF, Zandi S, Neumann A, Plumb I, Doulatov S, Chen J, April C, Fan JB, Iscove N, Dick JE
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.
van Galen P, Kreso A, Mbong N, Kent DG, Fitzmaurice T, Chambers JE, Xie S, Laurenti E, Hermans K, Eppert K, Marciniak SJ, Goodall JC, Green AR, Wouters BG, Wienholds E, Dick JE
Using Intravital Imaging to Understand how Acute Myeloid Leukemia Remodels the Bone Marrow Microenvironment In Vivo and how this Impacts Therapeutic Response
Principal investigators: Dacosta, Ralph S
Keywords: Acute Myeloid Leukemia; Bone Marrow; Fluorescence Microscopy; Hypoxia; Immune Cells; Intravital Optical Imaging; Leukemia Treatments; Microvasculature; Transcriptomics; Tumor Microenvironment
GLP-1 Receptor Agonists as a Preventive Strategy for Clonal Hematopoiesis-Driven Hematologic Cancers
Principal investigators: Chan, Steven M; Drucker, Daniel J; Xie, Stephanie Z
Keywords: Cancer Prevention; Clonal Fitness; Clonal Hematopoiesis; Diabetes; Glp1 Receptor Agonist; Hematological Malignancies; Hematopoietic Stem Cells; Inflammation; Metabolism; Myeloid Neoplasms
Discovery of sex-dimorphic leukemia-protective programs embedded in human hematopoietic stem cells
Principal investigators: Dick, John E; Kaufmann, Kerstin B
Keywords: Acute Myeloid Leukemia Biology,; Early Leukemogenesis; Human Hematopoietic Stem Cells; Human Leukemia Stem Cell Biology; Myeloproliferative Neoplasm Biology; Preleukemia; Sccut&Tag; Sex Dimorphisms; Single Cell Atac/Rna-Sequencing; Target-Seq,
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Laurence Pelletier and Brian Raught: 13 shared papers
- Brian Raught and Jason Moffat: 5 shared papers
- Laurence Pelletier and Jason Moffat: 4 shared papers
- Laurence Pelletier and Li Zhang: 1 shared paper
- Laurence Pelletier and Stephanie Xie: 1 shared paper
- Brian Raught and Li Zhang: 1 shared paper
- Brian Raught and Wei Xu: 1 shared paper
- Brian Raught and Stephanie Xie: 1 shared paper
- Kolja Eppert and Stephanie Xie: 1 shared paper
- Li Zhang and Stephanie Xie: 1 shared paper
- Jason Moffat and Stephanie Xie: 1 shared paper
- Wei Xu and Stephanie Xie: 1 shared paper
- Research Institute
- Genetics and Genome Biology
- Pediatrics
- Lunenfeld-Tanenbaum Research Institute
- Laboratory Medicine & Pathobiology
- Biostatistics Division
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Laurence Pelletier
Lunenfeld-Tanenbaum Research Institute
1 shared papers, latest 2026
Brian Raught
Research Institute
1 shared papers, latest 2026
Kolja Eppert
Pediatrics
1 shared papers, latest 2014
Li Zhang
Laboratory Medicine & Pathobiology
1 shared papers, latest 2026
Jason Moffat
Genetics and Genome Biology
1 shared papers, latest 2017
Wei Xu
Biostatistics Division
1 shared papers, latest 2015
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