Faculty profile

Yigal Dror

ResearcherGenetics and Genome BiologyUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Yigal Dror

Researcher

Genetics and Genome Biology

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
15 publications in the last five years, latest in 2026.
Senior (last) author on 7 recent papers, a sign of leading a research group.
Principal investigator on 6 research grants (6 CIHR), most recently in 2021.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

355

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Hematopoiesis Shwachman-Diamond Syndrome Bone Marrow Failure Inherited Bone Marrow Failure Syndromes Dnajc21 Ribosome Biogenesis Transcription Translation

Latest papers

Immunosuppressive therapy for severe aplastic anemia in children under the age of 3 years yields a high response rate: a North American collaborative study.
Haematologica · 2026 · senior author
Bone Marrow Failure as an Underrecognized Feature of KAT6A Syndrome.
Pediatric blood & cancer · 2026 · senior author
Passenger Lymphocyte Syndrome in Pediatric Lung Transplantation: A Recipient With Previous Hematopoietic Stem Cell Transplantation.
Pediatric transplantation · 2026

All 68 publications

Latest funding

Identifying novel strategies for leukemia prevention using zebrafish models of dnajc21-mutant Shwachman Diamond syndrome
CIHR · 2022 · Co-investigator
$910,350
Ribosome impairments, translation and bone marrow failure
CIHR · 2021 · Nominated PI
$901,170
Dissecting early and progressive leukemogenic impairments in the hematopoietic hierarchy and function using pre-leukemic inherited bone marrow failure syndromes as human disease models
CIHR · 2016 · Nominated PI
$1,005,975

All 7 grants and awards

68 publications.

Immunosuppressive therapy for severe aplastic anemia in children under the age of 3 years yields a high response rate: a North American collaborative study.

Dayagi TW, Willis L, Arnold SD, Boklan J, Cada M, Coates TD, Corriveau-Bourque C, Gamper CJ, Geddis AE, Glader B, Kupfer GM, Nakano TA, Olson TS, Rogers ZR, Shimamura A, Takemoto C, Thompson AA, Williams DA, Dror Y

Haematologica2026Senior author

DOI: 10.3324/haematol.2025.300232 PMID: 41988768

Bone Marrow Failure as an Underrecognized Feature of KAT6A Syndrome.

Shim YJ, Crooks B, Kang HJ, Hong KT, Choi JY, Jung HR, Seol CA, Mathew R, Dror Y

Pediatric blood & cancer2026Senior author

DOI: 10.1002/1545-5017.70023 PMID: 41449995

Passenger Lymphocyte Syndrome in Pediatric Lung Transplantation: A Recipient With Previous Hematopoietic Stem Cell Transplantation.

Avdimiretz N, Dror Y, Solomon M

Pediatric transplantation2026

DOI: 10.1111/petr.70256 PMID: 41578621

Expanding genetic landscape of inherited bone marrow failure syndromes: Insights from the Canadian Inherited Marrow Failure Registry (CIMFR) (2001–2023)

Shim YJ, Lee JH, Dayagi TW, Klaassen RJ, Pastore YD, Abish S, Steele M, Corriveau‐Bourque C, Breakey VR, Sinha R

British Journal of Haematology20261 citationsSenior author

DOI: 10.1111/bjh.70387

Steroid Responsiveness and Clinical Outcomes in Diamond–Blackfan Anemia: Analysis From the Canadian Inherited Marrow Failure Registry

Choi YB, Mathew R, Li H, Cada M, Klaassen RJ, Villeneuve S, Abish S, Corriveau‐Bourque C, Robitaille N, Steele M

European Journal of Haematology2026Senior author

DOI: 10.1111/ejh.70187

Outcomes of Dyskeratosis Congenita: Results From the Canadian Inherited Marrow Failure Registry

Al Nuaimi M, Catala A, Elias E, Lim YJ, Zlateska B, Klaassen RJ, Cuvelier GDE, Fernandez C, Rayar M, Steele M

Journal of Pediatric Hematology/Oncology2026

DOI: 10.1097/mph.0000000000003222

Successful Unmanipulated Haploidentical Hematopoietic Stem Cell Transplant With Post-transplant Cyclophosphamide in a Child With Down Syndrome and Myelodysplastic Syndrome.

Choed-Amphai C, Dror Y, Cada M, Schechter T, Krueger J, Ali M, Chopra Y

Journal of pediatric hematology/oncology2025

DOI: 10.1097/mph.0000000000003051 PMID: 40367189

Altered PTPN13-β-catenin interaction by pathogenic mutations and involvement of this axis in B-cell receptor signalling.

Cabrera-Riofrío DA, Li H, García-Calvo C, Sánchez-Bernal C, Sánchez-Yagüe J, Dror Y, Buey RM, Hernández-Hernández Á

Scientific reports2025

DOI: 10.1038/s41598-025-33151-y PMID: 41422331

Loss of Dnajc21 leads to cytopenia and altered nucleotide metabolism in zebrafish.

Ketharnathan S, Pokharel S, Prykhozhij SV, Cordeiro-Santanach A, Ban K, Dogan S, Hoang HD, Liebman MF, Leung E, Alain T, Alecu I, Bennett SAL, Čuperlović-Culf M, Dror Y, Berman JN

Leukemia2024

DOI: 10.1038/s41375-024-02367-8 PMID: 39138265

Aberrant early hematopoietic progenitor formation marks the onset of hematopoietic defects in Shwachman-Diamond syndrome.

Lagos-Monzon A, Ng S, Luca AM, Li H, Sabanayagam M, Benicio M, Moshiri H, Armstrong R, Tailor C, Kennedy M, Grunebaum E, Keller G, Dror Y

European journal of haematology2024Senior author

DOI: 10.1111/ejh.14260 PMID: 38967591

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Yigal Dror

Research

Latest papers

Latest funding

Immunosuppressive therapy for severe aplastic anemia in children under the age of 3 years yields a high response rate: a North American collaborative study.

Bone Marrow Failure as an Underrecognized Feature of KAT6A Syndrome.

Passenger Lymphocyte Syndrome in Pediatric Lung Transplantation: A Recipient With Previous Hematopoietic Stem Cell Transplantation.

Expanding genetic landscape of inherited bone marrow failure syndromes: Insights from the Canadian Inherited Marrow Failure Registry (CIMFR) (2001–2023)

Steroid Responsiveness and Clinical Outcomes in Diamond–Blackfan Anemia: Analysis From the Canadian Inherited Marrow Failure Registry

Outcomes of Dyskeratosis Congenita: Results From the Canadian Inherited Marrow Failure Registry

Successful Unmanipulated Haploidentical Hematopoietic Stem Cell Transplant With Post-transplant Cyclophosphamide in a Child With Down Syndrome and Myelodysplastic Syndrome.

Altered PTPN13-&#x3b2;-catenin interaction by pathogenic mutations and involvement of this axis in B-cell receptor signalling.

Loss of Dnajc21 leads to cytopenia and altered nucleotide metabolism in zebrafish.

Aberrant early hematopoietic progenitor formation marks the onset of hematopoietic defects in Shwachman-Diamond syndrome.

Identifying novel strategies for leukemia prevention using zebrafish models of dnajc21-mutant Shwachman Diamond syndrome

Ribosome impairments, translation and bone marrow failure

Dissecting early and progressive leukemogenic impairments in the hematopoietic hierarchy and function using pre-leukemic inherited bone marrow failure syndromes as human disease models

Dissecting the hematopoietic hierarchy and function using inherited human disease models of hematopoietic stem cell/progenitor loss

Deciphering the pathobiology of Shwachman Diamond syndrome hematopoietic failure using induced pluripotent stem cells

Inherited bone marrow failure syndromes: from genomic discoveries to biology

Genome-wide analysis of bone marrow failure-related genetic alterations in inherited bone marrow failure syndromes

Frequent collaborators

Vicky Breakey

Joseph Beyene

Lillian Sung

Michael Glogauer

David Chitayat

Robert Klaassen

Mohamed Abdelhaleem

Lani Lieberman

Sheila Weitzman

Eric Bouffet

Michel Duval

Diane Wherrett

Gavin Wilson

Johann Hitzler

David Malkin

Faiyaz Notta

Tommy Alain

Uma Athale

Gordon Keller

Aaron Schimmer

Altered PTPN13-β-catenin interaction by pathogenic mutations and involvement of this axis in B-cell receptor signalling.