Arghya Paul, Western University

Research

Drug Delivery Systems Nanomedicine Nanoparticles Polymers Regenerative Medicine Wound Healing Biomaterials Bone Repair

Latest papers

Cyclic peptide-based shear-thinning and self-healing hydrogels as injectable nanotherapeutics.
Biomaterials science · 2026 · senior author
On-Chip Microfluidic Production of Sonosensitizer-Loaded Liposomes for Sonodynamic Therapy of Hepatocellular Carcinoma.
ACS pharmacology & translational science · 2026 · senior author
DNA nanostructures as biomaterials for potential clinical applications.
Nanomedicine (London, England) · 2025 · senior author

All 28 publications

Latest funding

Molecular Imaging Tools for Visualizing Base Editing Therapy of Alpha-1 Anti-Trypsin Deficiency
CIHR · 2025 · Co-investigator
$994,500
Developing Tough, Elastomeric, Bioactive Hydrogel Dressings to Accelerate in situ Bone Repair
CIHR · 2025 · Nominated PI
$830,025
A New Enabling Technology to Manufacture CAR-T Cells for Personalized Cell Therapy
SSHRC · 2024 · Principal investigator
$125,000

All 12 grants and awards

28 publications.

01

Cyclic peptide-based shear-thinning and self-healing hydrogels as injectable nanotherapeutics.

Santillán F, Shamiya Y, Chakraborty A, Zahid AA, Veliz L, Lagugné-Labarthet F, Luyt LG, Paul A

Biomaterials science2026Senior author

DOI: 10.1039/d5bm01544h PMID: 41757763

02

On-Chip Microfluidic Production of Sonosensitizer-Loaded Liposomes for Sonodynamic Therapy of Hepatocellular Carcinoma.

Luo W, Zahid AA, Chakraborty A, Huang J, Kelly JJ, Borradaile N, Ronald JA, Paul A

ACS pharmacology & translational science2026Senior author

DOI: 10.1021/acsptsci.5c00522 PMID: 41536277

03

DNA nanostructures as biomaterials for potential clinical applications.

Huang J, Thivaharan T, Liu Y, Paul A

Nanomedicine (London, England)2025Senior author

DOI: 10.1080/17435889.2025.2579628 PMID: 41139133

04

Co-Delivery of Ca-MOF and Mg-MOF Using Nanoengineered Hydrogels to Promote In Situ Mineralization and Bone Defect Repair: In Vitro and In Vivo Analysis.

Choi CE, Liang C, Shamiya Y, Lee SJ, Paul A

Advanced healthcare materials2025Senior author

DOI: 10.1002/adhm.202502630 PMID: 40888230

05

Development of a tissue-specific bioscaffold for intestinal stem cell culture.

Kakar S, Derouet MF, Zhang L, Gillis CJ, Larsen F, Paul A, Flynn LE, Asfaha S

PloS one2025

DOI: 10.1371/journal.pone.0328898 PMID: 40768435

06

Surface-Engineered WS2 Nanohybrids for Implications in Biomedicine.

Chakraborty A, Luo W, Shamiya Y, Zahid AA, Grynyshyn MR, Bainbridge NA, Liu Y, Veliz L, Lagugné-Labarthet F, Liu L, Hamilton D, Paul A

ACS applied materials & interfaces2025Senior author

DOI: 10.1021/acsami.5c06846 PMID: 40631441

07

Nanominerals: a multifaceted biomaterial for regenerative medicine and drug delivery.

Chakraborty A, Luo W, Paul A

Expert opinion on drug delivery2025Senior author

DOI: 10.1080/17425247.2025.2491642 PMID: 40211899

08

NIR-Responsive ZIF-8 Metal-Organic Framework Nanohybrids with Photothermal, Antimicrobial, and Osteoinductive Properties to Prevent Implant Infection.

Choi CE, Shamiya Y, Luo W, Paul A

Macromolecular bioscience2025Senior author

DOI: 10.1002/mabi.202400594 PMID: 40014660

09

In Vitro Engineered ECM-incorporated Hydrogels for Osteochondral Tissue Repair: A Cell-Free Approach.

Coyle A, Chakraborty A, Huang J, Shamiya Y, Luo W, Paul A

Advanced healthcare materials2025Senior author

DOI: 10.1002/adhm.202402701 PMID: 39757463

10

Self-assembled DNA nanocarrier-enabled drug delivery for bone remodeling and antimicrobial applications.

Huang J, Chakraborty A, Shamiya Y, Luo W, Zahid AA, Paul A

npj biomedical innovations2025Senior author

DOI: 10.1038/s44385-025-00020-2 PMID: 40917680

Molecular Imaging Tools for Visualizing Base Editing Therapy of Alpha-1 Anti-Trypsin Deficiency

Co-investigatorCIHR2025Project Grant

Principal investigators: Ronald, John A

Keywords: Alpha-1 Anti-Trypsin Deficiency; Base Editing; Bioluminescence Imaging; Crispr; Genome Editing; Molecular Imaging; Positron Emission Tomography

$994,500

Developing Tough, Elastomeric, Bioactive Hydrogel Dressings to Accelerate in situ Bone Repair

Nominated PICIHR2025Project Grant

Principal investigators: Paul, Arghya

Keywords: Biomaterials; Bone Repair; Drug Delivery Systems; Hydrogel; Nanomedicine; Nanoparticles; Polymers; Regenerative Medicine; Tissue Repair; Wound Healing

$830,025

A New Enabling Technology to Manufacture CAR-T Cells for Personalized Cell Therapy

Principal investigatorSSHRC2024New Frontiers in Research Fund - Exploration

Principal investigators: Paul, Arghya

$125,000

Resetting the Chronic Skin Wound Edge: Investigating Contact Guidance and Suppression of Oxidative Stress Signaling to Enhance Keratinocyte Migration in Skin Re-epithelialization.

Co-investigatorCIHR2024Project Grant

Principal investigators: Hamilton, Douglas W

Keywords: Catalase-Skl; Cell Differentiation; Cell Migration; Keratinocytes; Microgrooved Membranes; Oxidative Stress; Rac Signaling; Re-Epithelialization; Reactive Oxygen Species; Skin Wound Chronicity

$742,050

Developing Tough, Elastomeric, Bioactive Hydrogel Dressings to Accelerate in situ Bone Repair

Nominated PICIHR2022Pro. Gr. - PA: Inst. of Musculoskeletal Health and Arthritis: IMHA Mandate Areas

Principal investigators: Paul, Arghya

Keywords: Biomaterial; Drug Delivery Systems; Growth Factors; Hydrogels; Nanomedicine; Nanoparticles; Polymers; Regenerative Medicine; Stem Cells; Wound Healing

$100,000

Engineered Mineral Nanoparticles and Nanocomposites: A Versatile Multifunctional Platform for 3D Bioprinting and Tissue Engineering

Principal investigatorNSERC2020Discovery Launch Supplement

Principal investigators: Paul, Arghya

$12,500

Engineered Mineral Nanoparticles and Nanocomposites: A Versatile Multifunctional Platform for 3D Bioprinting and Tissue Engineering

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Paul, Arghya

$190,000

Engineered Mineral Nanoparticles and Nanocomposites: A Versatile Multifunctional Platform for 3D Bioprinting and Tissue Engineering

Principal investigatorNSERC2020Discovery Grants Program - Accelerator Supplements

Principal investigators: Paul, Arghya

$120,000

Developing a Flow based High-Throughput Platform for Rapid and Efficient Stem Cell Banking

Principal investigatorSSHRC2019New Frontiers in Research Fund - Exploration

Principal investigators: Paul, Arghya

Keywords: Cellular Engineering; Stem Cells; Regenerative Medicine; Nanomedicine; Bio-Therapeutics; Nanoparticles; Microscale Technology

$273,175

Advanced Cell-instructive Materials and Biotherapeutics

Principal investigatorNSERC2018Canada Research Chairs

Principal investigators: Paul, Arghya

$95,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Chemical and Biochemical Engineering
Physiology and Pharmacology
Pathology and Laboratory Medicine
Anatomy and Cell Biology
Medicine
Other

Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Nica Borradaile

Physiology and Pharmacology

2 shared papers, latest 2026

Subrata Chakrabarti

Pathology and Laboratory Medicine

2 shared papers, latest 2024

Douglas Hamilton

Anatomy and Cell Biology

1 shared papers, latest 2025

Samuel Asfaha

Medicine

1 shared papers, latest 2025

Amin Rizkalla

Faculty

1 shared papers, latest 2023

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Drug Delivery Systems Dear Professor Paul, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Cyclic peptide-based shear-thinning and self-healing hydrogels as injectable nanotherapeutics." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Developing Tough, Elastomeric, Bioactive Hydrogel Dressings to Accelerate in situ Bone Repair" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]