Subrata Chakrabarti

Research

Read how they describe their research on their Western University profile.

Cardiac Functional Changes Cardiac Structural Changes Cardiomyocytes Diabetic Cardiomyopathy Endothelial Cells Methylation Non-Coding Rna Noncoding

Latest papers

Silencing of lncRNA HOTAIR Using Eyedrops as a Potential Treatment for Diabetes-Associated Retinal Dysregulation and Dysfunction.
Investigative ophthalmology & visual science · 2026 · senior author
Differential epigenetic regulation of glucose-induced alteration of miR-9 in retinal and cardiac endothelial cells.
PloS one · 2026 · senior author
JP2 and JCN Crosstalk Abrogate MURF1-Mediated JCN Ubiquitination and Degradation in Cardiomyocytes.
JACC. Basic to translational science · 2026

All 128 publications

Latest funding

Developing Tough, Elastomeric, Bioactive Hydrogel Dressings to Accelerate in situ Bone Repair
CIHR · 2025 · Co-investigator
$830,025
A New Enabling Technology to Manufacture CAR-T Cells for Personalized Cell Therapy
SSHRC · 2024 · Co-investigator
$125,000
Developing Tough, Elastomeric, Bioactive Hydrogel Dressings to Accelerate in situ Bone Repair
CIHR · 2022 · Co-investigator
$100,000

All 9 grants and awards

128 publications.

01

Silencing of lncRNA HOTAIR Using Eyedrops as a Potential Treatment for Diabetes-Associated Retinal Dysregulation and Dysfunction.

Wang E, Feng B, Chen S, Wang H, Ling T, Chakrabarti S

Investigative ophthalmology & visual science2026Senior author

DOI: 10.1167/iovs.67.1.24 PMID: 41805097

02

Differential epigenetic regulation of glucose-induced alteration of miR-9 in retinal and cardiac endothelial cells.

Wang E, Feng B, Chen S, Chakrabarti S

PloS one2026Senior author

DOI: 10.1371/journal.pone.0349188 PMID: 42166432

03

JP2 and JCN Crosstalk Abrogate MURF1-Mediated JCN Ubiquitination and Degradation in Cardiomyocytes.

Ji X, Huang Y, Wang J, Dong Z, Ni R, Su Z, Zheng D, Fan GC, Jones DL, Song LS, Chakrabarti S, Song J, Su Z, Peng T

JACC. Basic to translational science2026

DOI: 10.1016/j.jacbts.2026.101534 PMID: 42000606

04

DNA damage-inducible transcript 3 positively regulates RIPK1-mediated necroptosis.

Ni R, Cao T, Ji X, Peng A, Zhang Z, Fan GC, Stathopulos P, Chakrabarti S, Su Z, Peng T

Cell death and differentiation2025

DOI: 10.1038/s41418-024-01385-4 PMID: 39362992

05

Use of serum long non-coding RNA expression panel as a marker for diabetic retinopathy.

Wang E, Chen S, Ali A, Feng B, Liu S, Gonder J, Sheidow T, Hooper P, Chakrabarti S

Frontiers in cardiovascular medicine2025Senior author

DOI: 10.3389/fcvm.2025.1523997 PMID: 40271126

06

Ascorbyl palmitate nanofiber-reinforced hydrogels for drug delivery in soft issues.

Shamiya Y, Chakraborty A, Zahid AA, Bainbridge N, Guan J, Feng B, Pjontek D, Chakrabarti S, Paul A

Communications materials2024

DOI: 10.1038/s43246-024-00641-x PMID: 39309138

07

Differential microvascular endothelial cell responses in the retina in diabetes compared to the heart and kidneys, a spatial transcriptomic analysis.

Wang E, Feng B, Chen S, Su Z, Chakrabarti S

PloS one2024Senior author

DOI: 10.1371/journal.pone.0310949 PMID: 39739865

08

CircRNA_012164/MicroRNA-9-5p axis mediates cardiac fibrosis in diabetic cardiomyopathy.

Wang H, Wang EZR, Feng B, Chakrabarti S

PloS one2024Senior author

DOI: 10.1371/journal.pone.0302772 PMID: 39042659

09

Metabolic Dysfunction-Associated Steatohepatitis Detected by Neutrophilic Crown-Like Structures in Morbidly Obese Patients: A Multicenter and Clinicopathological Study.

Fan M, Song E, Zhang Y, Zhang P, Huang B, Yan K, Yang W, Chakrabarti S, Mahajan H, Yan S, Xu Y, Hua S, Liu W, Wang C, Xu A, Ye D

Research (Washington, D.C.)2024

DOI: 10.34133/research.0382 PMID: 38812532

10

Cardiac resident macrophages: Spatiotemporal distribution, development, physiological functions, and their translational potential on cardiac diseases.

Jin J, Wang Y, Liu Y, Chakrabarti S, Su Z

Acta pharmaceutica Sinica. B2024

DOI: 10.1016/j.apsb.2023.12.018 PMID: 38572111

Developing Tough, Elastomeric, Bioactive Hydrogel Dressings to Accelerate in situ Bone Repair

Co-investigatorCIHR2025Project Grant

Principal investigators: Paul, Arghya

Keywords: Biomaterials; Bone Repair; Drug Delivery Systems; Hydrogel; Nanomedicine; Nanoparticles; Polymers; Regenerative Medicine; Tissue Repair; Wound Healing

$830,025

A New Enabling Technology to Manufacture CAR-T Cells for Personalized Cell Therapy

Co-investigatorSSHRC2024New Frontiers in Research Fund - Exploration

Principal investigators: Paul, Arghya

$125,000

Developing Tough, Elastomeric, Bioactive Hydrogel Dressings to Accelerate in situ Bone Repair

Co-investigatorCIHR2022Pro. Gr. - PA: Inst. of Musculoskeletal Health and Arthritis: IMHA Mandate Areas

Principal investigators: Paul, Arghya

Keywords: Biomaterial; Drug Delivery Systems; Growth Factors; Hydrogels; Nanomedicine; Nanoparticles; Polymers; Regenerative Medicine; Stem Cells; Wound Healing

$100,000

L2M - NSERC Development of a tool for diagnosis of diabetic complications

Principal investigatorNSERC2022Idea to Innovation

Principal investigators: Chakrabarti, Subrata SUBR

$20,000

Novel mechanisms in diabetic cardiomyopathy

Nominated PICIHR2020Project Grant

Principal investigators: Chakrabarti, Subrata

Keywords: Cardiac Functional Changes; Cardiac Structural Changes; Cardiomyocytes; Diabetic Cardiomyopathy; Endothelial Cells; Methylation; Noncoding

$390,150

Novel mechanisms in diabetic cardiomyopathy

Nominated PICIHR2019Project Grant - PA: Epigenetics/epigenomics in human health or disease

Principal investigators: Chakrabarti, Subrata

Keywords: Cardiac Functional Changes; Cardiac Structural Changes; Cardiomyocytes; Diabetic Cardiomyopathy; Endothelial Cells; Methylation; Non-Coding Rna

$100,000

Novel mechanisms in diabetic cardiomyopathy

Nominated PICIHR2018Project Grant

Principal investigators: Chakrabarti, Subrata

Keywords: Cardiac Functional Changes; Cardiac Structural Changes; Cardiomyocytes; Diabetic Cardiomyopathy; Endothelial Cells; Methylation; Non-Coding Rna

$100,000

Endothelial cells in the pathophysiology of diabetic complications

Co-investigatorCIHR2015Planning and Dissemination Grant - Institute Community Support

Principal investigators: Khan, Zia A

Keywords: Cell-Cell Interactions; Diabetes; Endothelial Cells; Metabolism; Pericytes; Stem Cells

$16,275

Preventive Effects and the Mechanisms of action of a Novel Mutant of Fibroblast Growth Factor on Diabetic Cardiomyopathy

Nominated PICIHR2010China-Canada Joint Health Research Initiative

Principal investigators: Chakrabarti, Subrata; Li, Xiaokun

Keywords: Diabetes; Fibroblast Growth Factor; Heart; Metallothionein; Zinc

$146,100

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Morris Karmazyn

Physiology and Pharmacology

5 shared papers, latest 2009

Rokhsana Mortuza

Department of Medicine

4 shared papers, latest 2015

Bertha Garcia

PATHOLOGY & LABORATORY MEDICINE, Western University

3 shared papers, latest 2007

Yufeng Zuo

Dentistry - Schulich School of Medicine & Dentistry

3 shared papers, latest 2015

Bekim Sadikovic

PATHOLOGY & LABORATORY MEDICINE, Western University

3 shared papers, latest 2021

Tianqing Peng

Pathology and Laboratory Medicine

3 shared papers, latest 2026

Arghya Paul

Chemical and Biochemical Engineering

2 shared papers, latest 2024

William Wall

Department of Surgery

1 shared papers, latest 2007

Christopher Howlett

PATHOLOGY & LABORATORY MEDICINE, Western University

1 shared papers, latest 2018

Jeremy Parfitt

PATHOLOGY & LABORATORY MEDICINE, Western University

1 shared papers, latest 2019

Bret Wehrli

PATHOLOGY & LABORATORY MEDICINE, Western University

1 shared papers, latest 2015

Peter Stathopulos

Department of Physiology and Pharmacology

1 shared papers, latest 2025

Qi Zhang

PATHOLOGY & LABORATORY MEDICINE, Western University

1 shared papers, latest 2020

Mark Speechley

Department of Epidemiology and Biostatistics

1 shared papers, latest 2012

Selina Liu

Department of Obstetrics & Gynaecology

1 shared papers, latest 2025

Neil Parry

Department of Surgery

1 shared papers, latest 2005

Douglas Quan

Department of Surgery

1 shared papers, latest 2007

Savita Dhanvantari

Department of Medical Biophysics

1 shared papers, latest 2018

Qingping Feng

Physiology and Pharmacology

1 shared papers, latest 2010

Leonard Luyt

Department of Medical Imaging

1 shared papers, latest 2018

Frank Beier

Physiology and Pharmacology

1 shared papers, latest 2009

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2022

Subject: Prospective PhD student: Cardiac Functional Changes Dear Professor Chakrabarti, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Silencing of lncRNA HOTAIR Using Eyedrops as a Potential Treatment for Diabetes-Associated Retinal Dysregulation and Dysfunction." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "L2M - NSERC Development of a tool for diagnosis of diabetic complications" (2022), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Subrata Chakrabarti

Research

Latest papers

Latest funding

Silencing of lncRNA HOTAIR Using Eyedrops as a Potential Treatment for Diabetes-Associated Retinal Dysregulation and Dysfunction.

Differential epigenetic regulation of glucose-induced alteration of miR-9 in retinal and cardiac endothelial cells.

JP2 and JCN Crosstalk Abrogate MURF1-Mediated JCN Ubiquitination and Degradation in Cardiomyocytes.

DNA damage-inducible transcript 3 positively regulates RIPK1-mediated necroptosis.

Use of serum long non-coding RNA expression panel as a marker for diabetic retinopathy.

Ascorbyl palmitate nanofiber-reinforced hydrogels for drug delivery in soft issues.

Differential microvascular endothelial cell responses in the retina in diabetes compared to the heart and kidneys, a spatial transcriptomic analysis.

CircRNA_012164/MicroRNA-9-5p axis mediates cardiac fibrosis in diabetic cardiomyopathy.

Metabolic Dysfunction-Associated Steatohepatitis Detected by Neutrophilic Crown-Like Structures in Morbidly Obese Patients: A Multicenter and Clinicopathological Study.

Cardiac resident macrophages: Spatiotemporal distribution, development, physiological functions, and their translational potential on cardiac diseases.

Developing Tough, Elastomeric, Bioactive Hydrogel Dressings to Accelerate in situ Bone Repair

A New Enabling Technology to Manufacture CAR-T Cells for Personalized Cell Therapy

Developing Tough, Elastomeric, Bioactive Hydrogel Dressings to Accelerate in situ Bone Repair

L2M - NSERC Development of a tool for diagnosis of diabetic complications

Novel mechanisms in diabetic cardiomyopathy

Novel mechanisms in diabetic cardiomyopathy

Novel mechanisms in diabetic cardiomyopathy

Endothelial cells in the pathophysiology of diabetic complications

Preventive Effects and the Mechanisms of action of a Novel Mutant of Fibroblast Growth Factor on Diabetic Cardiomyopathy

Frequent collaborators

Morris Karmazyn

Rokhsana Mortuza

Bertha Garcia

Yufeng Zuo

Bekim Sadikovic

Tianqing Peng

Arghya Paul

Courtney Heather Coschi

Natasha Chandok

William Wall

Christopher Howlett

Jeremy Parfitt

Bret Wehrli

Peter Stathopulos

Qi Zhang

Mark Speechley

Selina Liu

Neil Parry

Douglas Quan

Ewa Cairns

Savita Dhanvantari

Varun Chaudhary

Qingping Feng

Neel Malhotra

Leonard Luyt

Frank Beier