This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Western University directory, so their courses may be missing. Find their university profile.
Research
Read how they describe their research on their Western University profile.
Latest papers
Quantifying electrostatic control of docking and binding energetics in functional Cx36 gap junctions.
Communications biology · 2026 · senior author
Human pannexin mutations and their implications in erosive osteoarthritis.
Proceedings of the National Academy of Sciences of the United States of America · 2026
Hydrogen peroxide reduces Cx40, Cx43, and Cx45 gap junction function.
Cell and tissue research · 2026 · senior author
Latest funding
- $180,000
Molecular domains determining gap junction channel properties
NSERC · 2020 · Principal investigator
- $745,389
Modeling connexin-linked disease
CIHR · 2016 · Co-investigator
- $100,000
Gap junction mutants and atrial fibrillation
CIHR · 2016 · Nominated PI
61 publications.
Quantifying electrostatic control of docking and binding energetics in functional Cx36 gap junctions.
Wong RS, Song Z, Zheng YT, Chen H, Zhao H, Bai D
Human pannexin mutations and their implications in erosive osteoarthritis.
Tang J, Lu J, Johnston D, Hoshijima K, Wakefield B, Bai D, Stathopulos PB, Thompson RJ, Lohman AW, Jurynec MJ, Beier F, Penuela S
Hydrogen peroxide reduces Cx40, Cx43, and Cx45 gap junction function.
Li YX, Bai D
Skin disease-associated GJB4 variants differentially influence connexin stability, cell viability and channel function.
Lucaciu SA, Leighton SE, Wong RS, Sekar V, Hauser A, Lai NA, Johnston D, Stathopulos PB, Bai D, Laird DW
ClinGen recuration of hearing loss-associated genes demonstrates significant changes in gene-disease validity over time.
Tshering KC, DiStefano MT, Oza AM, Ajuyah P, Webb R, Edoh E, Broeren E, Ratliff J, Gitau V, Paris K, Aburyyan A, Alexander J, Albano V, Bai D, Booth KTA, Buonfiglio PI, Charfeddine C, Dalamón V, Castillo ID, Moreno-Pelayo MA, Duzkale H, Dorshorst B, Faridi R, Kenna M, Lewis MA, Luo M, Lu Y, Mkaouar R, Matsunaga T, Nara K, Pandya A, Redfield S, Roux I, Schimmenti LA, Schrauwen I, Shaaban S, Shen J, Vona B, Smith RJ, Rehm HL, Azaiez H, Abou Tayoun AN, Amr SS, ClinGen Hearing Loss Clinical Domain Working Group
The rectification of heterotypic Cx46/Cx50 gap junction channels depends on intracellular magnesium.
Chen H, Bai D
Genetically engineered human embryonic kidney cells as a novel vehicle for dual patch clamp study of human gap junction channels.
Chen H, Li YX, Wong RS, Esseltine JL, Bai D
Cx31.1 can selectively intermix with co-expressed connexins to facilitate its assembly into gap junctions.
Leighton SE, Wong RS, Lucaciu SA, Hauser A, Johnston D, Stathopulos PB, Bai D, Penuela S, Laird DW
Human Cx50 Isoleucine177 prevents heterotypic docking and formation of functional gap junction channels with Cx43.
Wong RS, Chen H, Li YX, Esseltine JL, Stathopulos PB, Bai D
Inherited disease-linked arginine76/75 mutants in Cx50 and Cx45 showed impaired homotypic and heterotypic gap junction function, but not Cx43.
Li T, Chen H, Li X, Stathopulos PB, Bai D
Molecular domains determining gap junction channel properties
Principal investigators: Bai, Donglin
Modeling connexin-linked disease
Principal investigators: Laird, Dale W
Keywords: Connexin; Diseases; Gap Junctions
Gap junction mutants and atrial fibrillation
Principal investigators: Bai, Donglin
Keywords: Connexin; Gap Junction; Gating Of Gap Junction Channels; Patch Clamp
Molecular domains determining gap junction channel properties
Principal investigators: Bai, Donglin
Molecular domains determining gap junction channel properties
Principal investigators: Bai, Donglin
Molecular domains determining gap junction channel properties
Principal investigators: Bai, Donglin
Role of Cx26 and Cx30 in skin aging
Principal investigators: Laird, Dale W
Keywords: Connexins; Epidermis; Gap Junctions; Molecular Biology; Mutation; Skin Disease
Cx43 mutations linked to human disease
Principal investigators: Laird, Dale W; Bai, Donglin; Kidder, Gerald M
Keywords: Connexins; Disease; Gap Junctions; Mutations
Molecular domains determining gap junction channel properties
Principal investigators: Bai, Donglin
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Physiology and Pharmacology
- Department of Anatomy & Cell Biology
- Arthur Labatt Family School of Nursing
- Department of Physiology and Pharmacology
Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Silvia Penuela
Department of Anatomy & Cell Biology
3 shared papers, latest 2026
Ryan Chan
Arthur Labatt Family School of Nursing
1 shared papers, latest 2021
Morris Karmazyn
Physiology and Pharmacology
1 shared papers, latest 2010
Frank Beier
Physiology and Pharmacology
1 shared papers, latest 2026
Wei-Yang Lu
Department of Physiology and Pharmacology
1 shared papers, latest 2005
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.