Faculty profile
Morris Karmazyn
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Research
Latest papers
Targeting Gut Microbiome Dysbiosis as a Potentially Effective Therapeutic Approach for the Treatment of Heart Failure.
Reviews in cardiovascular medicine · 2025 · first author
Beyond Leptin and Adiponectin: The Diverse Roles of Adipokines in the Myocardial Hypertrophic Process and Heart Failure and Their Potential Contribution in Obesity.
International journal of molecular sciences · 2025 · first author
Special Issue "Cellular and Molecular Biology of Cardiac Hypertrophy and Heart Failure: Pathogenesis, Diagnostics and Treatment".
International journal of molecular sciences · 2025 · first author
Latest funding
- $686,220
Marked cardiac dysfunction and mortality associated with cardiac specific deletion of JAK2
CIHR · 2014 · Nominated PI
- $707,850
The Contribution of Leptin to Myocardial Hypertrophy, Remodelling and Failure: Mechanisms and Studies Into Leptin-Adiponectin Interactions
CIHR · 2012 · Nominated PI
- $745,884
Treatment with Ginseng as an Effective Cardiac Antihypertrophic and Antiremodelling Strategy
CIHR · 2012 · Nominated PI
66 publications.
Targeting Gut Microbiome Dysbiosis as a Potentially Effective Therapeutic Approach for the Treatment of Heart Failure.
Karmazyn M
Beyond Leptin and Adiponectin: The Diverse Roles of Adipokines in the Myocardial Hypertrophic Process and Heart Failure and Their Potential Contribution in Obesity.
Karmazyn M, Gan XT
Special Issue "Cellular and Molecular Biology of Cardiac Hypertrophy and Heart Failure: Pathogenesis, Diagnostics and Treatment".
Karmazyn M
Molecular and Cellular Mechanisms Underlying the Cardiac Hypertrophic and Pro-Remodelling Effects of Leptin.
Karmazyn M, Gan XT
Probiotics as potential treatments to reduce myocardial remodelling and heart failure via the gut-heart axis: State-of-the-art review.
Karmazyn M, Gan XT
Inhibition of Myocardial Remodeling and Heart Failure by Traditional Herbal Medications: Evidence from Ginseng and ginkgo biloba.
Karmazyn M, Gan XT
The Remaining Conundrum of the Role of the Na+/H+ Exchanger Isoform 1 (NHE1) in Cardiac Physiology and Pathology: Can It Be Rectified?
Karmazyn M, Pierce GN, Fliegel L
Inhibition of angiotensin II-induced hypertrophy and cardiac dysfunction by North American ginseng (Panax quinquefolius).
Tang X, Gan XT, Jong CJ, Rajapurohitam V, Karmazyn M
Chemical components of ginseng, their biotransformation products and their potential as treatment of hypertension.
Karmazyn M, Gan XT
Ginseng for the treatment of diabetes and diabetes-related cardiovascular complications: a discussion of the evidence 1.
Karmazyn M, Gan XT
Marked cardiac dysfunction and mortality associated with cardiac specific deletion of JAK2
Principal investigators: Karmazyn, Morris
Keywords: Arrhythmias; Cardiac Hypertrophy; Cell Signalling; Echocardiography; Heart Failure; Jak2; Knockout Mice
The Contribution of Leptin to Myocardial Hypertrophy, Remodelling and Failure: Mechanisms and Studies Into Leptin-Adiponectin Interactions
Principal investigators: Karmazyn, Morris
Keywords: Adiponectin; Cell Signalling; Heart Failure; Hypertrophy; Leptin; Mitochondria; Sex Differences
Treatment with Ginseng as an Effective Cardiac Antihypertrophic and Antiremodelling Strategy
Principal investigators: Karmazyn, Morris
Keywords: Apoptosis; Cardiac Hypertrophy; Ginseng; Heart Failure; Mitochondria
Role of Cytochrome P450-dependent Arachidonic Acid Metabolites in Hypertrophy and Heart Failure
Principal investigators: Karmazyn, Morris
Keywords: Arachidonic Acid; Cardiac Hypertrophy; Cellular Mechanisms; Cultured Adult Ventricular Myocytes; Cytochrome P450/Epoxygenase; Eets; Heart Failure; Rat Coronary Ligation
CRC Tier 1
Principal investigators: Karmazyn, Morris
Keywords: Chairs
Sodium-Hydrogen Exchange in Myocardial Remodelling and Heart Failure
Principal investigators: Karmazyn, Morris
Keywords: Cardiac Hypertrophy; Cellular Mechanisms; Cultured Adult Ventricular Myocytes; Heart Failure; Rat Coronary Ligation; Sodium-Hydrogen Exchange
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Tianqing Peng and Qingping Feng: 11 shared papers
- Morris Karmazyn and Subrata Chakrabarti: 5 shared papers
- Qingping Feng and Peter Chidiac: 4 shared papers
- Tianqing Peng and Subrata Chakrabarti: 3 shared papers
- Morris Karmazyn and Peter Chidiac: 2 shared papers
- Na Li and Morris Karmazyn: 1 shared paper
- Na Li and Qingping Feng: 1 shared paper
- Morris Karmazyn and Tianqing Peng: 1 shared paper
- Morris Karmazyn and Larry Fliegel: 1 shared paper
- Morris Karmazyn and Qingping Feng: 1 shared paper
- Morris Karmazyn and Donglin Bai: 1 shared paper
- Qingping Feng and Subrata Chakrabarti: 1 shared paper
- Physiology and Pharmacology
- Pathology and Laboratory Medicine
- Department of Physiology and Pharmacology
- Biochemistry
- Computing and Software
Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Subrata Chakrabarti
Pathology and Laboratory Medicine
5 shared papers, latest 2009
Peter Chidiac
Department of Physiology and Pharmacology
2 shared papers, latest 2006
Tianqing Peng
Pathology and Laboratory Medicine
1 shared papers, latest 2012
Larry Fliegel
Biochemistry
1 shared papers, latest 2022
Qingping Feng
Physiology and Pharmacology
1 shared papers, latest 2009
Donglin Bai
Physiology and Pharmacology
1 shared papers, latest 2010
Na Li
Computing and Software
1 shared papers, latest 2009
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