Faculty profile

David Stellwagen

ResearcherCentre for Research in NeurosciencesMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

David Stellwagen

Researcher

Centre for Research in Neurosciences

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
12 publications in the last five years, latest in 2026.
Senior (last) author on 5 recent papers, a sign of leading a research group.
Principal investigator on 9 research grants (5 CIHR, 4 NSERC), most recently in 2024.
Supervised 3 trainees who won CIHR awards, most recently in 2009.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Inflammation Plasticity Synapse Microglia Tnf Addiction Cocaine Cytokine

Latest papers

TNF-dependent regulation of synaptic plasticity and neuronal activity: implications for psychiatric disorders.
Molecular psychiatry · 2026 · senior author
Transregional astrocyte-dependent metaplasticity in the hippocampus.
Proceedings of the National Academy of Sciences of the United States of America · 2026
A screen of immune signaling molecules regulated by neuronal activity identifies interferon-gamma as a modulator of synaptic function and anxiety-like behavior.
Brain, behavior, and immunity · 2025 · senior author

All 32 publications

Latest funding

Glial regulation of synaptic plasticity
NSERC · 2024 · Principal investigator
$55,000
Creating an integrated platform for in vivo brain targeting and experimentation
NSERC · 2023 · Co-investigator
$149,090
The role of TNF in stress-induced synaptic and behavioural change
CIHR · 2020 · Nominated PI
$1,021,276

All 15 grants and awards

32 publications.

TNF-dependent regulation of synaptic plasticity and neuronal activity: implications for psychiatric disorders.

Moschou D, Adaïdi H, Stellwagen D

Molecular psychiatry2026Senior author

DOI: 10.1038/s41380-026-03861-4 PMID: 42706418

Transregional astrocyte-dependent metaplasticity in the hippocampus.

Sateesh S, Logan BJ, Suzuki M, Stellwagen D, Abraham WC

Proceedings of the National Academy of Sciences of the United States of America2026

DOI: 10.1073/pnas.2536065123 PMID: 42412941

A screen of immune signaling molecules regulated by neuronal activity identifies interferon-gamma as a modulator of synaptic function and anxiety-like behavior.

Heir R, Abuzgaya M, Adaïdi H, Franquin M, Abbasi Z, Stellwagen D

Brain, behavior, and immunity2025Senior author

DOI: 10.1016/j.bbi.2025.106066 PMID: 40759302

ABHD6 loss-of-function in mesoaccumbens postsynaptic but not presynaptic neurons prevents diet-induced obesity in male mice.

Lau D, Tobin S, Pribiag H, Nakajima S, Fisette A, Matthys D, Franco Flores AK, Peyot ML, Murthy Madiraju SR, Prentki M, Stellwagen D, Alquier T, Fulton S

Nature communications2024

DOI: 10.1038/s41467-024-54819-5 PMID: 39681558

Astrocytes Are the Source of TNF Mediating Homeostatic Synaptic Plasticity.

Heir R, Abbasi Z, Komal P, Altimimi HF, Franquin M, Moschou D, Chambon J, Stellwagen D

The Journal of neuroscience : the official journal of the Society for Neuroscience2024Senior author

DOI: 10.1523/jneurosci.2278-22.2024 PMID: 38395613

N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling.

Sakai M, Yu Z, Taniguchi M, Picotin R, Oyama N, Stellwagen D, Ono C, Kikuchi Y, Matsui K, Nakanishi M, Yoshii H, Furuyashiki T, Abe T, Tomita H

International journal of molecular sciences2023

DOI: 10.3390/ijms24043798 PMID: 36835209

Early TNF-Dependent Regulation of Excitatory and Inhibitory Synapses on Striatal Direct Pathway Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease.

Chambon J, Komal P, Lewitus GM, Kemp GM, Valade S, Adaïdi H, Al Bistami N, Stellwagen D

The Journal of neuroscience : the official journal of the Society for Neuroscience2023Senior author

DOI: 10.1523/jneurosci.1655-22.2022 PMID: 36517241

Sustained TNF signaling is required for the synaptic and anxiety-like behavioral response to acute stress.

Kemp GM, Altimimi HF, Nho Y, Heir R, Klyczek A, Stellwagen D

Molecular psychiatry2022Senior author

DOI: 10.1038/s41380-022-01737-x PMID: 36104437

Protein phosphatase-1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission.

Foley K, Altimimi H, Hou H, Zhang Y, McKee C, Papasergi-Scott MM, Yang H, Mayer A, Ward N, MacLean DM, Nairn AC, Stellwagen D, Xia H

Frontiers in synaptic neuroscience2022

DOI: 10.3389/fnsyn.2022.1021832 PMID: 36276179

Elevated TNF-α Leads to Neural Circuit Instability in the Absence of Interferon Regulatory Factor 8.

Feinberg PA, Becker SC, Chung L, Ferrari L, Stellwagen D, Anaclet C, Durán-Laforet V, Faust TE, Sumbria RK, Schafer DP

The Journal of neuroscience : the official journal of the Society for Neuroscience2022

DOI: 10.1523/jneurosci.0601-22.2022 PMID: 35790400

Glial regulation of synaptic plasticity

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: Stellwagen, David

Keywords: glia; synapse; plasticity; astrocyte; microglia; cytokine; tnf; ocular dominance; visual development; cortex

$55,000

Creating an integrated platform for in vivo brain targeting and experimentation

Co-investigatorNSERC2023Research Tools and Instruments

Principal investigators: Sabatini, Paul

$149,090

The role of TNF in stress-induced synaptic and behavioural change

Nominated PICIHR2020Project Grant

Principal investigators: Stellwagen, David

Keywords: Ampa; Anxiety; Gaba; Hippocampus; Inflammation; Microglia; Plasticity; Stress; Synapse; Tnf

$1,021,276

Reducing Homeostatic Synaptic Plasticity: A New Antiepileptogenic Approach to Cure Focal Epilepsy

Co-investigatorCIHR2019Project Grant

Principal investigators: Avoli, Massimo

Keywords: Eeg Recordings In Vivo; Epileptogenesis; Field/Whole Cell In Vitro Recordings; Hippocampus; Homeostatic Synaptic Plasticity; Mesial Temporal Lobe Epilepsy; Mice; Optogenetic Stimulation; Pilocarpine; Principal Cells

$749,700

Microglial regulation of cocaine self-administration in rats

Nominated PICIHR2018Project Grant

Principal investigators: Stellwagen, David

Keywords: Accubens; Addiction; Cocaine; Inflammation; Microglia; Reinstatement; Self-Administration; Tnf

$856,800

Glial regulation of synaptic plasticity

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Stellwagen, David

$308,000

Glial regulation of synaptic plasticity

Principal investigatorNSERC2016Discovery Grants Program - Accelerator Supplements

Principal investigators: Stellwagen, David

$120,000

The role of TNFalpha in striatal synaptic plasticity and the response to cocaine

Nominated PICIHR2014Operating Grant

Principal investigators: Stellwagen, David

Keywords: Addiction; Cocaine; Cytokine; Electrophysiology; Glia; Inflammation; Microscopy; Plasticity; Receptor Trafficking; Synapse

$776,819

The role of TNFalpha in synaptic plasticity and during neurodegeneration

Nominated PICIHR2013Operating Grant - Priority Announcement: ALS Canada Research Fund

Principal investigators: Stellwagen, David

Keywords: Als; Cytokine; Electrophysiology; Huntington'S Disease; Inflammation; Microscopy; Neurodegenerative Disease; Plasticity; Receptor Trafficking; Synapse

Confocal laser scanning microscope for high-resolution, 3-dimensional imaging in neuroscience

Co-investigatorNSERC2011Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Carbonetto, Salvatore

$139,519

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Something wrong or missing on this profile? Suggest a correction

David Stellwagen

Research

Latest papers

Latest funding

TNF-dependent regulation of synaptic plasticity and neuronal activity: implications for psychiatric disorders.

Transregional astrocyte-dependent metaplasticity in the hippocampus.

A screen of immune signaling molecules regulated by neuronal activity identifies interferon-gamma as a modulator of synaptic function and anxiety-like behavior.

ABHD6 loss-of-function in mesoaccumbens postsynaptic but not presynaptic neurons prevents diet-induced obesity in male mice.

Astrocytes Are the Source of TNF Mediating Homeostatic Synaptic Plasticity.

N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling.

Early TNF-Dependent Regulation of Excitatory and Inhibitory Synapses on Striatal Direct Pathway Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease.

Sustained TNF signaling is required for the synaptic and anxiety-like behavioral response to acute stress.

Protein phosphatase-1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission.

Elevated TNF-α Leads to Neural Circuit Instability in the Absence of Interferon Regulatory Factor 8.

Glial regulation of synaptic plasticity

Creating an integrated platform for in vivo brain targeting and experimentation

The role of TNF in stress-induced synaptic and behavioural change

Reducing Homeostatic Synaptic Plasticity: A New Antiepileptogenic Approach to Cure Focal Epilepsy

Microglial regulation of cocaine self-administration in rats

Glial regulation of synaptic plasticity

Glial regulation of synaptic plasticity

The role of TNFalpha in striatal synaptic plasticity and the response to cocaine

The role of TNFalpha in synaptic plasticity and during neurodegeneration

Confocal laser scanning microscope for high-resolution, 3-dimensional imaging in neuroscience

Frequent collaborators

Ivan Topisirovic

Jean-Francois Bouchard

Ivan Topisirovic

Stephanie Fulton

Stephanie Fulton

Adriana Di Polo

David Juncker

David Stellwagen

Research

Latest papers

Latest funding

TNF-dependent regulation of synaptic plasticity and neuronal activity: implications for psychiatric disorders.

Transregional astrocyte-dependent metaplasticity in the hippocampus.

A screen of immune signaling molecules regulated by neuronal activity identifies interferon-gamma as a modulator of synaptic function and anxiety-like behavior.

ABHD6 loss-of-function in mesoaccumbens postsynaptic but not presynaptic neurons prevents diet-induced obesity in male mice.

Astrocytes Are the Source of TNF Mediating Homeostatic Synaptic Plasticity.

N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-&#x3b1; Signaling.

Early TNF-Dependent Regulation of Excitatory and Inhibitory Synapses on Striatal Direct Pathway Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease.

Sustained TNF signaling is required for the synaptic and anxiety-like behavioral response to acute stress.

Protein phosphatase-1 inhibitor-2 promotes PP1&#x3b3; positive regulation of synaptic transmission.

Elevated TNF-&#x3b1; Leads to Neural Circuit Instability in the Absence of Interferon Regulatory Factor 8.

Glial regulation of synaptic plasticity

Creating an integrated platform for in vivo brain targeting and experimentation

The role of TNF in stress-induced synaptic and behavioural change

Reducing Homeostatic Synaptic Plasticity: A New Antiepileptogenic Approach to Cure Focal Epilepsy

Microglial regulation of cocaine self-administration in rats

Glial regulation of synaptic plasticity

Glial regulation of synaptic plasticity

The role of TNFalpha in striatal synaptic plasticity and the response to cocaine

The role of TNFalpha in synaptic plasticity and during neurodegeneration

Confocal laser scanning microscope for high-resolution, 3-dimensional imaging in neuroscience

Frequent collaborators

Ivan Topisirovic

Jean-Francois Bouchard

Ivan Topisirovic

Stephanie Fulton

Stephanie Fulton

Adriana Di Polo

David Juncker

N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling.

Protein phosphatase-1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission.

Elevated TNF-α Leads to Neural Circuit Instability in the Absence of Interferon Regulatory Factor 8.