Faculty profile

Douglas Arnold

ResearcherNeurology and NeurosurgeryMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.

Douglas Arnold

Researcher

Neurology and Neurosurgery

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
4 publications in the last five years, latest in 2025.
Principal investigator on 2 research grants (2 CIHR), most recently in 2016.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Multiple Sclerosis Biomarkers Demyelination Magnetic Resonance Imaging Progressive Multiple Sclerosis 3 Tesla 7 Tesla Cognitive Impairment

Latest papers

Deep learning detection of acute and sub-acute lesion activity from single-timepoint conventional brain MRI in multiple sclerosis.
Medical image analysis · 2025
Epstein-Barr Virus Strongly Associates With Pediatric Multiple Sclerosis, But Not Myelin Oligodendrocyte Glycoprotein-Antibody-Associated Disease.
Annals of neurology · 2024
Deep learning, data ramping, and uncertainty estimation for detecting artifacts in large, imbalanced databases of MRI images.
Medical image analysis · 2023

All 17 publications

Latest funding

Completing the picture of MS pathology with 7T MRI of the brain-spine axis
CIHR · 2025 · Co-investigator
$902,700
Unraveling Silent Progression in MS Using Advanced Quantitative MRI, PET Molecular Imaging and Computational Neuroanatomy
CIHR · 2022 · Co-investigator
$914,175
Brain oxidative stress and disability progression in multiple sclerosis
CIHR · 2016 · Co-investigator
$489,600

All 11 grants and awards

17 publications.

Deep learning detection of acute and sub-acute lesion activity from single-timepoint conventional brain MRI in multiple sclerosis.

Spinat Q, Audelan B, Jiang X, Caba B, Benichoux A, Ioannidou D, Teboul O, Komodakis N, Huijbers W, Gabr R, Gafson A, Elliott C, Arnold D, Paragios N, Belachew S

Medical image analysis2025

DOI: 10.1016/j.media.2025.103619 PMID: 40505211

Epstein-Barr Virus Strongly Associates With Pediatric Multiple Sclerosis, But Not Myelin Oligodendrocyte Glycoprotein-Antibody-Associated Disease.

Fadda G, Yea C, O'Mahony J, Waters P, Yeh EA, Marrie RA, Arnold D, Bar-Or A, Banwell B, Canadian Pediatric Demyelinating Disease Study Group

Annals of neurology2024

DOI: 10.1002/ana.26890 PMID: 38411340

Deep learning, data ramping, and uncertainty estimation for detecting artifacts in large, imbalanced databases of MRI images.

Pizarro R, Assemlal HE, Jegathambal SKB, Jubault T, Antel S, Arnold D, Shmuel A

Medical image analysis2023

DOI: 10.1016/j.media.2023.102942 PMID: 37797482

Disrupted cognitive development following pediatric acquired demyelinating syndromes: a longitudinal study.

De Somma E, O'Mahony J, Brown RA, Brooks BL, Yeh EA, Cardenas de La Parra A, Arnold D, Collins DL, Maranzano J, Narayanan S, Marrie RA, Bar-Or A, Banwell B, Till C

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence2022

DOI: 10.1080/09297049.2021.2002289 PMID: 34872458

The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes.

Tremlett H, Zhu F, Arnold D, Bar-Or A, Bernstein CN, Bonner C, Forbes JD, Graham M, Hart J, Knox NC, Marrie RA, Mirza AI, O'Mahony J, Van Domselaar G, Yeh EA, Zhao Y, Banwell B, Waubant E, US Network of Pediatric MS Centers, the Canadian Pediatric Demyelinating Disease Network

Annals of clinical and translational neurology2021

DOI: 10.1002/acn3.51476 PMID: 34889081

Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial.

Cree BAC, Cutter G, Wolinsky JS, Freedman MS, Comi G, Giovannoni G, Hartung HP, Arnold D, Kuhle J, Block V, Munschauer FE, Sedel F, Lublin FD, SPI2 investigative teams

The Lancet. Neurology2020

DOI: 10.1016/s1474-4422(20)30347-1 PMID: 33222767

The contribution of secondhand tobacco smoke exposure to pediatric multiple sclerosis risk.

Lavery AM, Collins BN, Waldman AT, Hart CN, Bar-Or A, Marrie RA, Arnold D, O'Mahony J, Banwell B

Multiple sclerosis (Houndmills, Basingstoke, England)2019

DOI: 10.1177/1352458518757089 PMID: 29393768

Local Indicators of Spatial Autocorrelation (LISA): Application to Blind Noise-Based Perceptual Quality Metric Index for Magnetic Resonance Images.

Osadebey M, Pedersen M, Arnold D, Wendel-Mitoraj K

Journal of imaging2019

DOI: 10.3390/jimaging5010020 PMID: 34465703

Using Deep Learning Algorithms to Automatically Identify the Brain MRI Contrast: Implications for Managing Large Databases.

Pizarro R, Assemlal HE, De Nigris D, Elliott C, Antel S, Arnold D, Shmuel A

Neuroinformatics2019

DOI: 10.1007/s12021-018-9387-8 PMID: 29956131

Application of calibrated fMRI in Alzheimer's disease.

Lajoie I, Nugent S, Debacker C, Dyson K, Tancredi FB, Badhwar A, Belleville S, Deschaintre Y, Bellec P, Doyon J, Bocti C, Gauthier S, Arnold D, Kergoat MJ, Chertkow H, Monchi O, Hoge RD

NeuroImage. Clinical2017

DOI: 10.1016/j.nicl.2017.05.009 PMID: 28560160

Completing the picture of MS pathology with 7T MRI of the brain-spine axis

Co-investigatorCIHR2025Project Grant

Principal investigators: Cohen-Adad, Julien

Keywords: B0 Shimming; Brain; Coil; Mri; Multiple Sclerosis; Open-Source Software; Rf Shimming; Spinal Cord; Ultra-High Field

$902,700

Unraveling Silent Progression in MS Using Advanced Quantitative MRI, PET Molecular Imaging and Computational Neuroanatomy

Co-investigatorCIHR2022Project Grant

Principal investigators: Rudko, David A

Keywords: Biophysical Modeling; Computational Neuroanatomy; Magnetic Resonance Imaging; Multiple Sclerosis; Neurodegeneration; Neuroinflammation; Quantitative Imaging

$914,175

Brain oxidative stress and disability progression in multiple sclerosis

Co-investigatorCIHR2016Project Grant

Principal investigators: Narayanan, Sridar

Keywords: Glutathione; Magnetic Resonance Spectroscopy; Multiple Sclerosis; Oxidative Stress; Progression

$489,600

Repeated Demyelination as an MRI Marker of Progressive Multiple Sclerosis

Nominated PICIHR2016Project Grant

Principal investigators: Arnold, Douglas L

Keywords: Biomarkers; Demyelination; Magnetic Resonance Imaging; Multiple Sclerosis; Progressive Multiple Sclerosis

$359,549

Magnetic Resonance Imaging of Multiple Sclerosis

Nominated PICIHR2013Operating Grant

Principal investigators: Arnold, Douglas L

Keywords: 3 Tesla; 7 Tesla; Cognitive Impairment; Cortical Lesions; Disability; Grey Matter; Magnetization Transfer Ratio; Mri; Multiple Sclerosis; Subpial Demyelination

$698,337

In vivo investigations of brain dopaminergic plasticity in humans

Co-investigatorCIHR2011Operating Grant

Principal investigators: Benkelfat, Chawki; Dagher, Alain; Leyton, Marco

Keywords: Addiction; Dopamine; Glutamate; Positron Emission Tomography; Psychostimulant; Sensitization

$1,163,010

Neural excitability in multiple sclerosis: Building the case for functional compensation.

Co-investigatorCIHR2011Operating Grant

Principal investigators: Koski, Lisa M

Keywords: Excitability; Functional Disability; Gaba; Inhibition; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetization Transfer Ratio; Multiple Sclerosis; Neuroplasticity; Transcranial Magnetic Stimulation

$277,921

Development and validation of MRI biomarkers for diagnosis and prognosis of prodromal Alzheimer's disease

Co-investigatorCIHR2010Operating Grant

Principal investigators: Collins, Donald L

Keywords: Biomarker; Diagnosis; Magnetic Resonance Imaging; Mild Cognitive Impairment; Prediction; Prodromal Alzheimer'S Disease

$383,741

In vivo investigations of brain dopaminergic plasticity in humans

Co-investigatorCIHR2010Operating Grant - PA: Prevention and Treatment of Illicit Drug Use

Principal investigators: Benkelfat, Chawki; Dagher, Alain; Leyton, Marco

Keywords: Addiction; Dopamine; Glutamate; Positron Emission Tomography; Psychostimulant; Sensitization

$100,000

Quantitative magnetic resonance imaging of multiple sclerosis

Co-investigatorCIHR2009Operating Grant

Principal investigators: Pike, G. Bruce

Keywords: Magnetic Resonance Imaging; Magnetization Transfer; Mr Relaxometry; Multiple Sclerosis

$805,242

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Douglas Arnold

Research

Latest papers

Latest funding

Deep learning detection of acute and sub-acute lesion activity from single-timepoint conventional brain MRI in multiple sclerosis.

Epstein-Barr Virus Strongly Associates With Pediatric Multiple Sclerosis, But Not Myelin Oligodendrocyte Glycoprotein-Antibody-Associated Disease.

Deep learning, data ramping, and uncertainty estimation for detecting artifacts in large, imbalanced databases of MRI images.

Disrupted cognitive development following pediatric acquired demyelinating syndromes: a longitudinal study.

The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes.

Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial.

The contribution of secondhand tobacco smoke exposure to pediatric multiple sclerosis risk.

Local Indicators of Spatial Autocorrelation (LISA): Application to Blind Noise-Based Perceptual Quality Metric Index for Magnetic Resonance Images.

Using Deep Learning Algorithms to Automatically Identify the Brain MRI Contrast: Implications for Managing Large Databases.

Application of calibrated fMRI in Alzheimer's disease.

Frequent collaborators

Amit Bar-Or

Amir Shmuel

Sylvie Belleville

Pierre Bellec

Jack Antel

Julien Doyon

Oury Monchi

Sylvie Belleville

Sridar Narayanan

Serge Gauthier

Julien Doyon

Marie-Jeanne Kergoat

Christine Till

Giulia Fadda

Amanpreet Badhwar

Howard Chertkow

Amanpreet Badhwar

Pierre Bellec

Marie-Jeanne Kergoat

Helen Tremlett

Oury Monchi

Serge Gauthier