Faculty profile

Serge Gauthier

ResearcherUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses and email address may be missing. Find their university profile.

Serge Gauthier

Researcher

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
103 publications in the last five years, latest in 2026.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 1 research grant (1 CIHR), most recently in 2016.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

256

Publications

372

Citations

116

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Dietary Intervention Nutrition And Aging Nutrition And Brain Activity Nutrition And Cognition Nutrition And Elderly Nutrition And Mri Rct Subjective Cognitive Impairment (Sci)

Latest papers

Clinical, imaging and blood biomarker outcomes in a Phase 3 clinical trial of tau aggregation inhibitor hydromethylthionine mesylate in mild cognitive impairment and mild to moderate dementia due to Alzheimer's disease.
The journal of prevention of Alzheimer's disease · 2026
Functional network phenotypes of mild behavioural impairment: cognitive effects moderated by amyloid.
Alzheimer's research & therapy · 2026
Choroidal-ventricular system abnormalities are linked to amyloid-β aggregation in Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026

All 256 publications

Latest funding

Quantitative electroencephalography in rapid-eye-movement (REM) sleep: an early marker of cholinergic neurodegeneration in mild cognitive impairment
CIHR · 2016 · Co-investigator
$665,550
Increasing vitamin K status through supplementation to improve cognition in older individuals at risk of cognitive impairment: a randomized, double-blind, placebo-controlled study
CIHR · 2016 · Principal investigator
$100,000
Explaining activation changes during the early stages of Alzheimer's disease and promoting processes of compensation and brain plasticity
CIHR · 2016 · Co-investigator
$1,731,723

All 11 grants and awards

From the 150 most recent of 256 publications.

Clinical, imaging and blood biomarker outcomes in a Phase 3 clinical trial of tau aggregation inhibitor hydromethylthionine mesylate in mild cognitive impairment and mild to moderate dementia due to Alzheimer's disease.

Wischik CM, Stefanacci R, Bentham P, Gauthier S, Zetterberg H, Wilcock GK, Froelich L, Burns A, MacSweeney E, Ballard C, Yu JT, Choon TS, Asvatourian V, Muehlemann N, Priel J, Kook K, Sullivan T, Downie D, Miller S, Pringle C, Storey JMD, Baddeley T, Harrington CR, Penny LK, Arastoo M, Staff R, Sandu AL, Shiells H, Lo S, Nazlee N, Evans E, Hull C, Schelter BO

The journal of prevention of Alzheimer's disease2026

DOI: 10.1016/j.tjpad.2026.100480 PMID: 41570392

Functional network phenotypes of mild behavioural impairment: cognitive effects moderated by amyloid.

Ng KP, Chong JSX, Lussier F, Therriault J, Rahmouni N, Savard M, Stevenson J, Pascoal T, Gauthier S, Rosa-Neto P, Zhou JH

Alzheimer's research & therapy2026

DOI: 10.1186/s13195-026-01980-2 PMID: 41668114

Choroidal-ventricular system abnormalities are linked to amyloid-β aggregation in Alzheimer's disease.

Hosseini SA, Aumont E, Rahmouni N, Woo MS, Macedo AC, Hall B, Chan T, Therriault J, Trudel L, Zheng Y, Bezgin G, Lebrun A, Arias JF, Socualaya KQ, Tissot C, Servaes S, Wang YT, Oliva-Lopez D, Mitchell S, Hopewell R, Hsiao CH, Saleh C, Stevenson J, Lussier F, Wu L, Chu M, Chawla S, Fonov V, Massarweh G, Medina YI, Soucy JP, Provost K, Rudko DA, Karikari T, Benedet AL, Ashton NJ, Zetterberg H, Montembeault M, Vitali P, Blennow K, Gauthier S, Collins DL, Klostranec J, Pascoal TA, Rosa-Neto P

Alzheimer's & dementia : the journal of the Alzheimer's Association2026

DOI: 10.1002/alz.71205 PMID: 41738400

Hippocampal Atrophy on Magnetic Resonance Imaging as a Surrogate Marker for Clinical Benefit and Neurodegeneration in Early Symptomatic Alzheimer's Disease: Synthesis of Evidence from Observational and Interventional Trials.

Abushakra S, Doraiswamy PM, Hey JA, Tosun D, Barkhof F, Barakos J, Petrella J, Kesslak JP, Power A, Sabbagh M, Porsteinsson A, Cohen S, Gauthier S, Ritchie C, Watson D, McSweeney E, Boada M, Liang E, Bracoud L, McLaine R, Flint S, Schaefer JF, Yu J, Bray M, Hendrix S, Dickson S, Durrant A, Albayrak A, Tolar M

CNS drugs2026

DOI: 10.1007/s40263-025-01251-y PMID: 41324786

Optimized atlas for early tau-PET staging via native space segmentations.

Aumont E, Hall BJ, Chan T, Trudel L, Bezgin G, Hosseini SA, Therriault J, Macedo AC, Fernández Arias J, Rahmouni N, Servaes S, Vitali P, Stevenson J, Fonov V, Montembeault M, Klostranec J, Iturria-Medina Y, Gauthier S, Rosa-Neto P, Alzheimer’s Disease Neuroimaging Initiative

Neurobiology of aging2026

DOI: 10.1016/j.neurobiolaging.2025.11.002 PMID: 41237676

Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer's disease.

Ferrari-Souza JP, Povala G, Rahmouni N, Bellaver B, Ferreira PCL, De Bastiani MA, Leffa DT, Lussier FZ, Aguzzoli CS, Brum WS, Carello-Collar G, Borelli WV, Therriault J, Macedo AC, Servaes S, Stevenson J, Pola I, Gauthier S, Souza DO, Schilling LP, Lourenco MV, Triana-Baltzer G, Kolb HC, Benedet AL, Ashton NJ, Tudorascu DL, Zetterberg H, Blennow K, Johnson SC, Pascoal TA, Rosa-Neto P, Zimmer ER

Nature neuroscience2026

DOI: 10.1038/s41593-025-02103-0 PMID: 41198899

Quantitative susceptibility mapping of the brain is associated with inflammatory changes in Alzheimer's disease related areas.

Hosseini SA, Servaes S, Macedo AC, Aumont E, Rahmouni N, Chan T, Therriault J, Trudel L, Hall B, Wang YT, Arias JF, Bezgin G, Zheng Y, Gonçalves MP, Quispialaya Socualaya K, Woo MS, Tissot C, Oliva-Lopez D, Li J, Mitchell S, Lebrun A, Hopewell R, Chawla S, Fonov V, Massarweh G, Medina YI, Soucy JP, Montembeault M, Vitali P, Blennow K, Karikari TK, Benedet AL, Ashton NJ, Zetterberg H, Pascoal TA, Gauthier S, Klostranec J, Zhuang H, Cho J, Collins DL, Wang Y, Rudko DA, Rosa-Neto P

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2026

DOI: 10.1177/0271678x261417193 PMID: 41656561

Aβ- and tau-associated neuroinflammatory signatures in Alzheimer's disease.

Bellaver B, Povala G, De Bastiani MA, Pola I, Ferreira PCL, Bauer-Negrini G, Ferrari-Souza JP, Leffa DT, Lussier FZ, Therriault J, Rahmouni N, Stevenson J, Servaes S, Patira R, Gauthier S, Tudorascu DL, Karikari TK, Ashton N, Blennow K, Zetterberg H, Zimmer ER, Benedet AL, Rosa-Neto P, Pascoal TA

Alzheimer's & dementia (New York, N. Y.)2026

DOI: 10.1002/trc2.70275 PMID: 42325592

Posterior cortical atrophy and logopenic variant primary progressive aphasia are more specific for Alzheimer's disease pathology than probable Alzheimer's disease.

Trudel L, Therriault J, Macedo AC, Rahmouni N, Soucy JP, Gauthier S, Vitali P, Guiot MC, Hazrati LN, Rosa-Neto P

Brain communications2026

DOI: 10.1093/braincomms/fcag304 PMID: 42582463

Assessment of clinical and neuroimaging efficacy of treatment targeting tau pathology in mild cognitive impairment and mild to moderate Alzheimer's disease with hydromethylthionine mesylate using external control data.

Schelter BO, Shiells H, Lo S, Nazlee N, Evans E, Bentham P, Gauthier S, Zetterberg H, Wilcock GK, Froelich L, Burns A, MacSweeney E, Ballard C, Yu JT, Choon TS, Asvatourian V, Muehlemann N, Priel J, Kook K, Sullivan T, Downie D, Miller S, Pringle C, Storey JMD, Baddeley T, Harrington CR, Staff R, Sandu AL, Hull C, Stefanacci R, Wischik CM, Alzheimer's Disease Neuroimaging Initiative

The journal of prevention of Alzheimer's disease2026

DOI: 10.1016/j.tjpad.2026.100560 PMID: 42000569

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Serge Gauthier

Research

Latest papers

Latest funding

Clinical, imaging and blood biomarker outcomes in a Phase 3 clinical trial of tau aggregation inhibitor hydromethylthionine mesylate in mild cognitive impairment and mild to moderate dementia due to Alzheimer's disease.

Functional network phenotypes of mild behavioural impairment: cognitive effects moderated by amyloid.

Choroidal-ventricular system abnormalities are linked to amyloid-&#x3b2; aggregation in Alzheimer's disease.

Hippocampal Atrophy on Magnetic Resonance Imaging as a Surrogate Marker for Clinical Benefit and Neurodegeneration in Early Symptomatic Alzheimer's Disease: Synthesis of Evidence from Observational and Interventional Trials.

Optimized atlas for early tau-PET staging via native space segmentations.

Microglia modulate A&#x3b2;-dependent astrocyte reactivity in Alzheimer's disease.

Quantitative susceptibility mapping of the brain is associated with inflammatory changes in Alzheimer's disease related areas.

A&#x3b2;- and tau-associated neuroinflammatory signatures in Alzheimer's disease.

Posterior cortical atrophy and logopenic variant primary progressive aphasia are more specific for Alzheimer's disease pathology than probable Alzheimer's disease.

Assessment of clinical and neuroimaging efficacy of treatment targeting tau pathology in mild cognitive impairment and mild to moderate Alzheimer's disease with hydromethylthionine mesylate using external control data.

Frequent collaborators

Serge Gauthier

Pedro Rosa-Neto

Jean-Paul Soucy

Zahinoor Ismail

Sylvie Belleville

Sylvie Belleville

Maxime Montembeault

Judes Poirier

Mario Masellis

Yasser Iturria Medina

Paramita Saha Chaudhuri

Marie-Jeanne Kergoat

Marie-Jeanne Kergoat

Howard Chertkow

Soham Rej

Julie Ottoy

Simon Duchesne

Nathan Herrmann

Isabelle Vedel

Howard Chertkow

Saskia Sivananthan

Simon Ducharme

Michael Borrie

Linda Lee

Linda Lee

Sylvia Villeneuve

Robert Laforce

Howard Chertkow

Isabelle Vedel

Jianping Jia

Amir Shmuel

Jean-Philippe Sylvestre

John Breitner

Maged Goubran

Alexey Kostikov

Sanjeev Kumar

Marie-Christine Ouellet

Jacques Montplaisir

Olivier Beauchet

Naguib Mechawar

Choroidal-ventricular system abnormalities are linked to amyloid-β aggregation in Alzheimer's disease.

Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer's disease.

Aβ- and tau-associated neuroinflammatory signatures in Alzheimer's disease.