Faculty profile

Guillaume Butler-Laporte

ResearcherInfectious DiseasesMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Guillaume Butler-Laporte

Researcher

Infectious Diseases

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
50 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 1 research grant (1 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

1,435

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Immunomodulation Platform Trial Pneumocystis Pneumonia Randomized Controlled Trial Secondary Prophylaxis Treatment

Latest papers

Initial Vancomycin Taper for the Prevention of Recurrent Clostridioides difficile Infection
JAMA Network Open · 2026
Protein mediators of chronic kidney disease in Type 2 diabetes: A mendelian randomization study.
PLoS medicine · 2026
Proteome-wide Mendelian randomization identifies APOM and TNXB as actionable mediators of steroid-sensitive nephrotic syndrome.
Pediatric nephrology (Berlin, Germany) · 2026

All 86 publications

Latest funding

An international platform for finding the optimal therapies for Pneumocystis jirovecii pneumonia: The PCP Platform
CIHR · 2024 · Principal investigator
$1,683,000
Clopidogrel vs. Aspirin in S. aureus Bacteremia (Clopido-SNAP)
CIHR · 2024 · Co-investigator
$539,325
Dabigatran for the adjunctive treatment of Staphylococcus aureus bacteremia: the DABI-SNAP nested randomized controlled trial
CIHR · 2024 · Co-investigator
$539,325

All 9 grants and awards

86 publications.

Initial Vancomycin Taper for the Prevention of Recurrent Clostridioides difficile Infection

McDonald EG, Butler-Laporte G, Brophy JM, Elsayed S, Frenette C, Huseen I, Loo VG, Moran K, Coburn B, Hota SS

JAMA Network Open20268 citations

DOI: 10.1001/jamanetworkopen.2025.60495

Protein mediators of chronic kidney disease in Type 2 diabetes: A mendelian randomization study.

Liang KYH, Zheng TM, Tan D, Sasako T, Ilboudo Y, Chen Y, Butler-Laporte G, Yoshiji S, Richards JB

PLoS medicine2026

DOI: 10.1371/journal.pmed.1004802 PMID: 42726788

Proteome-wide Mendelian randomization identifies APOM and TNXB as actionable mediators of steroid-sensitive nephrotic syndrome.

Heydari D, Langlois S, Norouzi M, Myette RL, Samuel S, Zhou S, Takano T, Butler-Laporte G, Downie ML

Pediatric nephrology (Berlin, Germany)2026

DOI: 10.1007/s00467-026-07280-z PMID: 41961272

The illusion of causality: instruments, colliders, and acute kidney injury in sepsis.

Hamilton F, Lee TC, Davey Smith G, Hartwig FP, Butler-Laporte G

American journal of respiratory and critical care medicine2026Senior author

DOI: 10.1093/ajrccm/aamag208 PMID: 42118120

An Accurate Genetic Colocalisation Method for the HLA Locus.

Butler-Laporte G, Lu T, Morris S, Zhang W, Band G, Hamilton F, Chong A, Lin K, Nanjala R, Richards JB, Lee MH, Yang L, Yao P, Li L, Chen Z, Luo Y, Millwood IY, Walters RG, Mentzer AJ

HLA2026First author

DOI: 10.1111/tan.70759 PMID: 42174329

Author Correction: HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases.

Butler-Laporte G, Farjoun J, Nakanishi T, Lu T, Abner E, Chen Y, Hultström M, Metspalu A, Milani L, Mägi R, Nelis M, Hudjashov G, Estonian Biobank Research Team, Yoshiji S, Ilboudo Y, Liang KYH, Su CY, Willett JDS, Esko T, Zhou S, Forgetta V, Taliun D, Richards JB

Communications biology2026First author

DOI: 10.1038/s42003-026-09877-4 PMID: 41927953

Cefepime and Mortality: A Systematic Review and Bayesian Meta-Analysis.

Sohani ZN, Zhong YJ, Afshar A, Assiri BA, Gore G, Cheng MP, Lieu A, Serero J, Hamilton F, Lawandi A, Paul M, Yahav D, Albuquerque AM, Butler-Laporte G, McDonald EG, Lee TC

JAMA network open2026

DOI: 10.1001/jamanetworkopen.2026.33017 PMID: 42720951

Human Genetic Analysis Reveals Circulating Alpha-1 Antitrypsin Level as a Protective Factor in Sepsis.

Tan D, Zhang P, Zheng TM, Liang KYH, Su CY, Chen Y, Lu T, Richards JB, Chong AY, Lawler PR, Hamilton F, Mentzer AJ, Knight JC, Butler-Laporte G

medRxiv : the preprint server for health sciences2026Senior author

DOI: 10.64898/2026.03.25.26349312 PMID: 41929286

Does Piperacillin-Tazobactam Increase Mortality Risk Compared With Cefepime? Collider Bias and the Importance of Assumptions in Instrumental Variable Analyses.

Hamilton F, Lee TC, Davey Smith G, Hartwig FP, Butler-Laporte G

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America2026Senior author

DOI: 10.1093/cid/ciaf317 PMID: 40581713

Genetic evidence suggests a protective role of immunoglobulin M in Alzheimer's disease.

Peng S, Butler-Laporte G, Johnson SC, Engelman CD, Lu T

Alzheimer's & dementia : the journal of the Alzheimer's Association2026

DOI: 10.1002/alz.71865 PMID: 42764449

An international platform for finding the optimal therapies for Pneumocystis jirovecii pneumonia: The PCP Platform

Principal investigatorCIHR2024Project Grant

Principal investigators: Lee, Todd C; Benedetti, Andrea; Bhagani, Sanjay; Boyles, Tom; Butler-Laporte, Guillaume; Cheng, Matthew P; McDonald, Emily G; McGuinty, Michaeline; Nakashima, Kei; Schwartz, Ilan S; Slavin, Monica; So, Miranda; Tan, Darrell H; Yong, Michelle

Keywords: Immunomodulation; Platform Trial; Pneumocystis; Pneumonia; Randomized Controlled Trial; Secondary Prophylaxis; Treatment

$1,683,000

Clopidogrel vs. Aspirin in S. aureus Bacteremia (Clopido-SNAP)

Co-investigatorCIHR2024Project Grant

Principal investigators: Lee, Todd C; Cheng, Matthew P; Daneman, Nick; Davis, Joshua; Goodman, Anna L; Lawler, Patrick R; McDonald, Emily G; Mertz, Dominik; Paul, Mical; Siegal, Deborah M; Tong, Steven; Walls, Genevieve

Keywords: Antithrombotic Therapy; Bacteremia; Randomized Controlled Trial; Staphylococcus Aureus

$539,325

Dabigatran for the adjunctive treatment of Staphylococcus aureus bacteremia: the DABI-SNAP nested randomized controlled trial

Co-investigatorCIHR2024Project Grant

Principal investigators: McDonald, Emily G; Cheng, Matthew P; Daneman, Nick; Davis, Joshua; Goodman, Anna L; Lawandi, Alexander; Lawler, Patrick R; Lee, Todd C; Mertz, Dominik; Paul, Mical; Siegal, Deborah M; Tong, Steven; Walls, Genevieve

Keywords: Adjunctive Therapies; Anticoagulants; Comparative Effectiveness Trial; Desirability Of Ordinal Outcomes Rating; Infectious Diseases; Nested Trials; Platform Trial; Pragmatic Trials; Staph Aureus Bacteremia

$539,325

A Randomized Controlled Trial of Oral Antimicrobial Therapy for Patients with Staphylococcus aureus Bacteremia: The Early Oral Switch Domain in the Staphylococcus aureus Network Adaptive Trial (EOS-SNAP)

Co-investigatorCIHR2024Project Grant

Principal investigators: Cheng, Matthew P; Bai, Anthony D; Daley, Peter; Daneman, Nick; Grant, Jennifer; Lawandi, Alexander; Lee, Todd C; MacFadden, Derek R; McDonald, Emily G; Somayaji, Ranjani; Wuerz, Terence

Keywords: Bacteremia; Bloodstream Infection; Clinical Trial; Oral Antibiotics; Staphylococcus Aureus

$1,705,952

Expanding the Staphylococcus Aureus Network Adaptive Platform (SNAP^2)

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects

Principal investigators: Lee, Todd C; Cheng, Matthew P; Daneman, Nick; Davis, Joshua; Goodman, Anna L; Johnstone, Jennie; Lawandi, Alexander; Lye, David C; McDonald, Emily G; Paul, Mical; Tong, Steven; Walls, Genevieve; Wuerz, Terence

Keywords: Combination Therapy; Endocarditis; Randomized Controlled Trial; Staphylococcus Aureus Bacteremia

$1,999,745

Expanding the Staphylococcus Aureus Network Adaptive Platform (SNAP^2)

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects - Indirect Costs

Keywords: Combination Therapy; Endocarditis; Randomized Controlled Trial; Staphylococcus Aureus Bacteremia

$499,936

PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN)

Co-investigatorCIHR2021Project Grant

Principal investigators: Lee, Todd C; Cheng, Matthew P; McDonald, Emily G

Keywords: Antibiotic Resistance; Bacteremia; Bloodstream Infection; E. Coli; Esbl; K. Pneumoniae; Non-Inferiority; Pragmatic; Randomized Controlled Trial

$371,024

The S. aureus Network Adaptive Platform Trial (SNAP) Canada: A Randomized Controlled Trial for Penicillin-susceptible, Methicillin-susceptible, and Methicillin-resistant Staphylococcus aureus Bloodstream Infections in Hospitalized Patients

Co-investigatorCIHR2020Project Grant

Principal investigators: Cheng, Matthew P; Daneman, Nick; Johnstone, Jennie; Lee, Todd C

Keywords: Bacteremia; Randomized Controlled Trial; Staphylococcus Aureus

$1,139,852

Initial vancomycin taper for the prevention of recurrent Clostridium difficile infection

Co-investigatorCIHR2018Project Grant

Principal investigators: Lee, Todd C; McDonald, Emily G

Keywords: Clostridium Dificile; Prevention; Recurrence; Vancomycin

$378,676

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Guillaume Butler-Laporte

Research

Latest papers

Latest funding

Initial Vancomycin Taper for the Prevention of Recurrent Clostridioides difficile Infection

Protein mediators of chronic kidney disease in Type 2 diabetes: A mendelian randomization study.

Proteome-wide Mendelian randomization identifies APOM and TNXB as actionable mediators of steroid-sensitive nephrotic syndrome.

The illusion of causality: instruments, colliders, and acute kidney injury in sepsis.

An Accurate Genetic Colocalisation Method for the HLA Locus.

Author Correction: HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases.

Cefepime and Mortality: A Systematic Review and Bayesian Meta-Analysis.

Human Genetic Analysis Reveals Circulating Alpha-1 Antitrypsin Level as a Protective Factor in Sepsis.

Does Piperacillin-Tazobactam Increase Mortality Risk Compared With Cefepime? Collider Bias and the Importance of Assumptions in Instrumental Variable Analyses.

Genetic evidence suggests a protective role of immunoglobulin M in Alzheimer's disease.

Frequent collaborators

Sirui Zhou

Satoshi Yoshiji

Vincent Mooser

Alexander Lawandi

Jonathan Afilalo

Marc Afilalo

Mark Lathrop

Mark Loeb

Carson Lo

Adam Komorowski

Guillaume Bourque

Erwin Schurr

Miranda So

Madeleine Durand

Bryan Coburn

Daniel Taliun

Zain Chagla

Brent Richards

Madeleine Durand

Emilie Trinh

Susan Samuel

Salman Qureshi

Srinivas Murthy

Derek MacFadden