Faculty profile

Mark Lathrop

ResearcherMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.

Mark Lathrop

Researcher

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
28 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 6 research grants (6 CIHR), most recently in 2017.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

130

Publications

218

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Crc Chronic Inflammation Crohn'S Disease Diet (Environment)Genetics Gnotobiotic Mice (Germ-Free)Humanized Mice Inflammatory Bowel Diseases

Latest papers

A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases
Nature Communications · 2026
Benchmarking of Oxford Nanopore whole genome sequencing for germline variant and CpG methylation detection across Canada's national platform for genome sequencing and analysis.
Frontiers in genetics · 2026
Identification of Two Rare Variants in Iranian Families With Familial Sudden Cardiac Death.
International journal of genomics · 2026

All 130 publications

Latest funding

Viral diversity and immune escape variants in vulnerable individuals post-vaccination.
CIHR · 2021 · Co-investigator
Genomics of Aortic Stenosis - an International Collaboration
CIHR · 2018 · Co-investigator
$722,925
Canada Research Chair - Tier 1 - CIHR Funded
CIHR · 2017 · Nominated PI
$1,400,000

All 18 grants and awards

130 publications.

A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases

Chechi K, Chakaroun R, Myridakis A, Forslund-Startceva SK, Fromentin S, Nielsen T, Aron-Wisneswky J, Belda E, Prifti E, Lassen PB

Nature Communications20264 citations

DOI: 10.1038/s41467-026-69405-0

Benchmarking of Oxford Nanopore whole genome sequencing for germline variant and CpG methylation detection across Canada's national platform for genome sequencing and analysis.

Galvez JH, Mastromatteo S, O'Neill K, Eveleigh R, Djambazian H, Thiruvahindrapuram B, Chuah E, Chen SH, Hajianpour A, Wang Z, Paton TA, Desai S, Pullenayegum S, He L, Pandoh P, Zhao Y, Mungall K, Mungall AJ, Wintle RF, Bourque G, Scherer SW, Jones S, Lathrop M, McLaren M, Ragoussis J

Frontiers in genetics2026

DOI: 10.3389/fgene.2026.1863034 PMID: 42644200

Identification of Two Rare Variants in Iranian Families With Familial Sudden Cardiac Death.

Tahmasebivand M, Mehvari S, Ghodratpour F, Khoram Khorshid H, Malekzadeh R, Najafipour R, Riazalhosseini Y, Lathrop M, Najmabadi H, Kahrizi K

International journal of genomics2026

DOI: 10.1155/ijog/5965922 PMID: 41510139

Functional assessment of a convergent gene network underlying allergic diseases and IgE.

Eranti P, Vernet R, Linhard C, Ge B, Beaumier L, Madore AM, Chanoine S, Tremblay BL, Shao X, Pin I, Lathrop M, Grundberg E, Siroux V, Pastinen T, Laprise C, Bouzigon E, Demenais F

The Journal of allergy and clinical immunology2026

DOI: 10.1016/j.jaci.2026.02.009 PMID: 41724407

Fetal hemoglobin enables malaria parasite growth in sickle cells but augments production of transmission stage parasites.

Lavazec C, Loucoubar C, Dupuy F, Bureau JF, Casadémont I, Gonçalves B, Thein SL, Lathrop M, Laurance S, Roussel C, Le Van Kim C, Colin Y, De Montalembert M, Sakuntabhai A, Paul RE

PloS one2025

DOI: 10.1371/journal.pone.0325797 PMID: 40627625

CpG methylation changes associated with hyperglycemia in type 1 diabetes occur at angiogenic glomerular and retinal gene loci.

Shao X, Le Fur S, Cheung W, Belot MP, Perge K, Bouhours-Nouet N, Bensignor C, Levaillant L, Ge B, Kwan T, Lathrop M, Pastinen T, Bougnères P

Scientific reports2025

DOI: 10.1038/s41598-024-82698-9 PMID: 40341532

Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat.

Brial F, Le Lay A, Rouch C, Henrion E, Bourgey M, Bourque G, Lathrop M, Magnan C, Gauguier D

Molecular brain2025

DOI: 10.1186/s13041-025-01176-z PMID: 39920851

Gastrectomy promoted diabetes remission involves the molecular clock and epigenetic mechanisms in a rat model of lean type 2 diabetes.

Le Lay A, Brial F, Rouch C, Shao X, Bourgey M, Sonomura K, Ou H, Ghezzal S, Vincent M, Rugard M, Audouze K, Ragoussis J, Matsuda F, Bourque G, Grundberg E, Lathrop M, Magnan C, Gauguier D

Scientific reports2025

DOI: 10.1038/s41598-025-29273-y PMID: 41360887

Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease.

Caro I, Western D, Namba S, Sun N, Kawaguchi S, He Y, Fujita M, Roshchupkin G, D'Aoust T, Duperron MG, Sargurupremraj M, Tsuchida A, Koido M, Ahmadi M, Yang C, Timsina J, Ibanez L, Matsuda K, Suzuki Y, Oda Y, Kanai A, Jandaghi P, Munter M, Auld D, Astafeva I, Puerta R, Rotter JI, Psaty BM, Bis JC, Longstreth WT, Couffinhal T, García-González P, Pytel V, Marquié M, Cano A, Boada M, Joliot M, Lathrop M, Le Grand Q, Launer LJ, Wardlaw JM, Heiman M, Ruiz A, Matthews PM, Seshadri S, Fornage M, Adams H, Mishra A, Trégouët DA, Okada Y, Kellis M, De Jager PL, Tzourio C, Kamatani Y, Matsuda F, Cruchaga C, Debette S

Nature aging2025

DOI: 10.1038/s43587-025-01006-w PMID: 41266628

Quantitative 1H-NMR spectroscopy identifies metabolites and lipoprotein subclasses associated with intermediate phenotypes of chronic diseases in the Japanese Nagahama Study.

Ou H, Kawaguchi S, Brial F, Sonomura K, Kawaguchi T, Gravel AE, Das SK, Auld D, Tabara Y, Jean-Claude BJ, Lathrop M, Matsuda F, Gauguier D

Scientific reports2025

DOI: 10.1038/s41598-025-12305-y PMID: 40858625

Viral diversity and immune escape variants in vulnerable individuals post-vaccination.

Co-investigatorCIHR2021Operating Grant: Emerging COVID-19 Research Gaps and Priorities - Variants

Principal investigators: Piccirillo, Ciriaco A

Keywords: Computational Biology; Hematological Malignancies; Immune Escape Variants; Immunosenescence; Mutations; Serology; T Cells; Vaccines; Viral Genomics; Viral Transmission

Genomics of Aortic Stenosis - an International Collaboration

Co-investigatorCIHR2018Project Grant

Principal investigators: Thanassoulis, George; Engert, James C

Keywords: Aortic Valve; Cardiovascular Disease; Genome-Wide Association; Genomics; Mendelian Randomization

$722,925

Canada Research Chair - Tier 1 - CIHR Funded

Nominated PICIHR2017Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Lathrop, Mark

Keywords: Crc

$1,400,000

Genomics of Aortic Stenosis - an International Collaboration

Co-investigatorCIHR2017Project Grant

Principal investigators: Thanassoulis, George; Engert, James C

Keywords: Aortic Valve; Cardiovascular Disease; Genome Wide Association; Geomics; Mendelian Randomization

$100,000

Multidimensional Epigenomics Mapping Centre (EMC) at McGill

Co-investigatorCIHR2016CEEHRC Phase II: Platform Centres Renewal

Principal investigators: Pastinen, Tomi; Bourque, Guillaume

Keywords: Epigenetics; Epigenomics; Genetics; Genomics

$4,210,000

Genomics of Aortic Stenosis - An international collaboration

Co-investigatorCIHR2016Project Grant

Principal investigators: Thanassoulis, George; Engert, James C

Keywords: Aortic Stenosis; Cardiovascular Disease; Genetic Epidemiology; Genomewide Association Studies; Genomics; Mendelian Randomization; Valve Disease

$100,000

BRain Imaging, cognition, Dementia and next generation GEnomics: a Transdisciplinary approach to search for risk and protective factors of neurodegenerative disease

Co-investigatorCIHR2015Operating Grant: Joint Programme on Neurodegenerative Disease Research (JPND)

Principal investigators: Pastinen, Tomi

Keywords: Alzheimer Disease; Cognition; Methylation; Mri-Markers Of Brain Aging; Next Generation Sequencing; Population-Based Longitudinal Cohort

$333,000

Understanding etiology of metabolic diseases by integrative genomics and epigenomics approaches

Co-investigatorCIHR2015Foundation Grant

Principal investigators: Grundberg, Elin

Keywords: Epigenetics; Next-Generation Sequencing; Obesity; Type 2 Diabetes

$1,004,884

Genetic analysis of susceptibility to infections and to inflammation

Co-investigatorCIHR2015Foundation Grant

Principal investigators: Gros, Philippe

Keywords: Genetic Analysis; Infections; Inflammation; Inflammatory Diseases; Interferon Response Factor; Malaria; Myeloid Cells; Primary Immunodeficiencies; Tuberculosis

$2,170,632

Integrative Epigenomics of Obesity and Metabolic Complications - The Obesity Epigenomics Trilateral Project

Co-investigatorCIHR2015Team Grant: Epigenomics of Complex Diseases

Principal investigators: Grundberg, Elin; Vohl, Marie-Claude

Keywords: Bariatric Surgery; Epigenetics; Obesity; Remission; Type 2 Diabetes

$429,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Mark Lathrop

Research

Latest papers

Latest funding

A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases

Benchmarking of Oxford Nanopore whole genome sequencing for germline variant and CpG methylation detection across Canada's national platform for genome sequencing and analysis.

Identification of Two Rare Variants in Iranian Families With Familial Sudden Cardiac Death.

Functional assessment of a convergent gene network underlying allergic diseases and IgE.

Fetal hemoglobin enables malaria parasite growth in sickle cells but augments production of transmission stage parasites.

CpG methylation changes associated with hyperglycemia in type 1 diabetes occur at angiogenic glomerular and retinal gene loci.

Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat.

Gastrectomy promoted diabetes remission involves the molecular clock and epigenetic mechanisms in a rat model of lean type 2 diabetes.

Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease.

Quantitative 1H-NMR spectroscopy identifies metabolites and lipoprotein subclasses associated with intermediate phenotypes of chronic diseases in the Japanese Nagahama Study.

Frequent collaborators

Guillaume Bourque

Yasser Riazalhosseini

Elin Grundberg

Jacek Majewski

Tomi Pastinen

Catherine Laprise

Philippe Gros

George Thanassoulis

Marie-Claude Vohl

Guillaume Butler-Laporte

David Langlais

Vincent Mooser

Patricia Conrod

Sidong Huang

Rafik Tadros

Mathieu Blanchette

Tomas Paus

Parminder Raina

Maya Saleh

Subburaj Ilangumaran

Samantha Gruenheid

Faith Davis

David Messika-Zeitoun

Julie Lessard

Morag Park

Susan Kirkland

Michael Ohh

Robert Sladek

Yohan Bossé

Christina Wolfson

Guillaume Pare

Philippe Pibarot

Sasha Bernatsky

Alexandre Prat

Michel Roger

Seema Mital

Lauren Griffith

Cynthia Balion

Tapas Mondal

Karen Mossman