This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Activation of the PDGFRα-Nrf2 pathway mediates impaired adipocyte differentiation in bone marrow mesenchymal stem cells lacking Nck1.
Cell communication and signaling : CCS · 2020 · senior author
Harnessing adipogenesis to prevent obesity.
Adipocyte · 2019 · senior author
Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes.
iScience · 2018 · senior author
Latest funding
- $100,000
Deciphering the role of the interaction of Nck1 and PERK in regulating pancreatic beta cell function and survival
CIHR · 2016 · Nominated PI
- $130,000
Phosphorylation of Nck
NSERC · 2012 · Principal investigator
- $703,064
Role of the Adaptor Protein Nck in the Pathogenesis of Insulin Resistance and Type 2 Diabetes
CIHR · 2011 · Nominated PI
23 publications.
Activation of the PDGFRα-Nrf2 pathway mediates impaired adipocyte differentiation in bone marrow mesenchymal stem cells lacking Nck1.
Haider N, Larose L
Harnessing adipogenesis to prevent obesity.
Haider N, Larose L
Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes.
Haider N, Dusseault J, Larose L
Peptide-based sequestration of the adaptor protein Nck1 in pancreatic β cells enhances insulin biogenesis and protects against diabetogenic stresses.
Kefalas G, Jouvet N, Baldwin C, Estall JL, Larose L
PERK leads a hub dictating pancreatic β cell homoeostasis.
Kefalas G, Larose L
IRE1α links Nck1 deficiency to attenuated PTP1B expression in HepG2 cells.
Li H, Li B, Larose L
Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy.
Kaufman DR, Papillon J, Larose L, Iwawaki T, Cybulsky AV
Dissecting the molecular mechanisms that impair stress granule formation in aging cells.
Moujaber O, Mahboubi H, Kodiha M, Bouttier M, Bednarz K, Bakshi R, White J, Larose L, Colmegna I, Stochaj U
Nck2 Deficiency in Mice Results in Increased Adiposity Associated With Adipocyte Hypertrophy and Enhanced Adipogenesis.
Dusseault J, Li B, Haider N, Goyette MA, Côté JF, Larose L
mTORC1 and CK2 coordinate ternary and eIF4F complex assembly.
Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, Tenkerian C, Morita M, Balanathan P, Jean-Jean O, Stambolic V, Trost M, Furic L, Larose L, Koromilas AE, Asano K, Litchfield D, Larsson O, Topisirovic I
Deciphering the role of the interaction of Nck1 and PERK in regulating pancreatic beta cell function and survival
Principal investigators: Larose, Louise
Keywords: Adaptor Protein Nck; Diabetes; Islet Transplantation; Pancreatic Beta Cells; Pancreatic Islets; Protein Kinase Perk; Unfolded Protein Response
Phosphorylation of Nck
Principal investigators: Larose, Louise
Role of the Adaptor Protein Nck in the Pathogenesis of Insulin Resistance and Type 2 Diabetes
Principal investigators: Larose, Louise
Keywords: Adaptor Proteins; Diabetes; Endoplasmic Reticulum Stress; Glucose And Lipid Metabolism And Homeostasis; Hepatic Gluconeogenesis; Insulin Signaling And Resistance; Nck Knock Out Mice; Obesity; Primary Hepatocytes; Unfolded Protein Response
Colloque "Signalisation Québec 2012"
Principal investigators: Côté, Jean-François
Keywords: Cancer; Transduction Du Signal
Phosphorylation of Nck
Principal investigators: Larose, Louise
Phosphorylation of Nck
Principal investigators: Larose, Louise
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Ivan Topisirovic and Ivan Topisirovic: 77 shared papers
- Morag Park and Ivan Topisirovic: 2 shared papers
- Tomoko Takano and Louise Larose: 1 shared paper
- John White and Louise Larose: 1 shared paper
- David Litchfield and Vuk Stambolic: 1 shared paper
- David Litchfield and Ivan Topisirovic: 1 shared paper
- David Litchfield and Louise Larose: 1 shared paper
- David Litchfield and Ivan Topisirovic: 1 shared paper
- Vuk Stambolic and Ivan Topisirovic: 1 shared paper
- Vuk Stambolic and Louise Larose: 1 shared paper
- Vuk Stambolic and Ivan Topisirovic: 1 shared paper
- Morag Park and Louise Larose: 1 shared paper
- Morag Park and Ivan Topisirovic: 1 shared paper
- Ivan Topisirovic and Louise Larose: 1 shared paper
- Louise Larose and Ivan Topisirovic: 1 shared paper
- Medicine
- Biochemistry
- Lady Davis Institute for Medical Research
- Physiology
- Oncology
- Medicine/Nephrology
- Research
- Other
Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Ivan Topisirovic
Faculty
1 shared papers, latest 2016
Tomoko Takano
Medicine/Nephrology
1 shared papers, latest 2006
John White
Physiology
1 shared papers, latest 2017
David Litchfield
Biochemistry
1 shared papers, latest 2016
Vuk Stambolic
Research
1 shared papers, latest 2016
Morag Park
Oncology
1 shared papers, latest 2010
Ivan Topisirovic
Lady Davis Institute for Medical Research
1 shared papers, latest 2016
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