Faculty profile

Pnina Brodt

ResearcherSurgeryMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Pnina Brodt

Researcher

Surgery

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
7 publications in the last five years, latest in 2025.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 3 research grants (3 CIHR), most recently in 2019.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Colon Cancer Cytokines Estrogen Liver Metastasis Pancreatic Cancer Tumor Microenvironment Breast Cancer

Latest papers

Nanoparticle encapsulation enables systemic IGF-Trap delivery to inhibit intracerebral glioma growth.
Neuro-oncology · 2025 · senior author
MICAL2 Promotes Pancreatic Cancer Growth and Metastasis.
Cancer research · 2025
Transcranial Magnetic Stimulation Enhances the Therapeutic Effect of IGF-Trap in Intracerebral Glioma Models.
Pharmaceuticals (Basel, Switzerland) · 2024 · senior author

All 40 publications

Latest funding

Aberrant MNK1/2 signaling as a mechanism involved in breast cancer liver metastasis.
CIHR · 2020 · Co-investigator
$60,000
Regulatory circuits controlling the immune microenvironment of liver metastases
CIHR · 2019 · Nominated PI
$807,075
An IGF-Trap for the treatment of breast cancer: consolidation of the pre-clinical profile and commercialization.
CIHR · 2015 · Nominated PI
$299,934

All 7 grants and awards

40 publications.

Nanoparticle encapsulation enables systemic IGF-Trap delivery to inhibit intracerebral glioma growth.

Chen YM, Chambon J, Moquin A, Hashimoto M, Perrino S, Leibovitch M, Benslimane Y, Haçariz O, Yang Q, Nakano I, Meehan B, Rak J, Gagné S, Brodt P

Neuro-oncology2025Senior author

DOI: 10.1093/neuonc/noaf011 PMID: 39879581

MICAL2 Promotes Pancreatic Cancer Growth and Metastasis.

Garg B, Khan S, Courelli AS, Panneerpandian P, Sheik Pran Babu D, Mose ES, Gulay KCM, Sharma S, Sood D, Wenzel AT, Martsinkovskiy A, Rajbhandari N, Patel J, Jaquish D, Esparza E, Jaque K, Aggarwal N, Lambies G, D'Ippolito A, Austgen K, Johnston B, Orlando DA, Jang GH, Gallinger S, Goodfellow E, Brodt P, Commisso C, Tamayo P, Mesirov JP, Tiriac H, Lowy AM

Cancer research2025

DOI: 10.1158/0008-5472.can-24-0744 PMID: 39745352

Transcranial Magnetic Stimulation Enhances the Therapeutic Effect of IGF-Trap in Intracerebral Glioma Models.

Perrino S, Vazana U, Prager O, Schori L, Ben-Arie G, Minarik A, Chen YM, Haçariz O, Hashimoto M, Roth Y, Pell GS, Friedman A, Brodt P

Pharmaceuticals (Basel, Switzerland)2024Senior author

DOI: 10.3390/ph17121607 PMID: 39770449

Blocking tumor-intrinsic MNK1 kinase restricts metabolic adaptation and diminishes liver metastasis.

Preston SEJ, Dahabieh MS, Flores González RE, Gonçalves C, Richard VR, Leibovitch M, Dakin E, Papadopoulos T, Lopez Naranjo C, McCallum PA, Huang F, Gagnon N, Perrino S, Zahedi RP, Borchers CH, Jones RG, Brodt P, Miller WH, Del Rincón SV

Science advances2024

DOI: 10.1126/sciadv.adi7673 PMID: 39270021

Estrogen Receptor Blockade Potentiates Immunotherapy for Liver Metastases by Altering the Liver Immunosuppressive Microenvironment.

Benslimane Y, Amalfi K, Lapin S, Perrino S, Brodt P

Cancer research communications2024Senior author

DOI: 10.1158/2767-9764.crc-24-0196 PMID: 39007345

Targeting the IGF-Axis in Cultured Pediatric High-Grade Glioma Cells Inhibits Cell Cycle Progression and Survival.

Chen YM, Leibovitch M, Zeinieh M, Jabado N, Brodt P

Pharmaceuticals (Basel, Switzerland)2023Senior author

DOI: 10.3390/ph16020297 PMID: 37259440

Histopathological growth patterns of liver metastasis: updated consensus guidelines for pattern scoring, perspectives and recent mechanistic insights.

Latacz E, Höppener D, Bohlok A, Leduc S, Tabariès S, Fernández Moro C, Lugassy C, Nyström H, Bozóky B, Floris G, Geyer N, Brodt P, Llado L, Van Mileghem L, De Schepper M, Majeed AW, Lazaris A, Dirix P, Zhang Q, Petrillo SK, Vankerckhove S, Joye I, Meyer Y, Gregorieff A, Roig NR, Vidal-Vanaclocha F, Denis L, Oliveira RC, Metrakos P, Grünhagen DJ, Nagtegaal ID, Mollevi DG, Jarnagin WR, D'Angelica MI, Reynolds AR, Doukas M, Desmedt C, Dirix L, Donckier V, Siegel PM, Barnhill R, Gerling M, Verhoef C, Vermeulen PB

British journal of cancer2022

DOI: 10.1038/s41416-022-01859-7 PMID: 35650276

Targeting the IGF-Axis Potentiates Immunotherapy for Pancreatic Ductal Adenocarcinoma Liver Metastases by Altering the Immunosuppressive Microenvironment.

Hashimoto M, Konda JD, Perrino S, Celia Fernandez M, Lowy AM, Brodt P

Molecular cancer therapeutics2021Senior author

DOI: 10.1158/1535-7163.mct-20-0144 PMID: 34552012

The unique immune microenvironment of liver metastases: Challenges and opportunities.

Ciner AT, Jones K, Muschel RJ, Brodt P

Seminars in cancer biology2021Senior author

DOI: 10.1016/j.semcancer.2020.06.003 PMID: 32526354

Liver metastases.

Tsilimigras DI, Brodt P, Clavien PA, Muschel RJ, D'Angelica MI, Endo I, Parks RW, Doyle M, de Santibañes E, Pawlik TM

Nature reviews. Disease primers2021

DOI: 10.1038/s41572-021-00261-6 PMID: 33859205

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Pnina Brodt

Research

Latest papers

Latest funding

Nanoparticle encapsulation enables systemic IGF-Trap delivery to inhibit intracerebral glioma growth.

MICAL2 Promotes Pancreatic Cancer Growth and Metastasis.

Transcranial Magnetic Stimulation Enhances the Therapeutic Effect of IGF-Trap in Intracerebral Glioma Models.

Blocking tumor-intrinsic MNK1 kinase restricts metabolic adaptation and diminishes liver metastasis.

Estrogen Receptor Blockade Potentiates Immunotherapy for Liver Metastases by Altering the Liver Immunosuppressive Microenvironment.

Targeting the IGF-Axis in Cultured Pediatric High-Grade Glioma Cells Inhibits Cell Cycle Progression and Survival.

Histopathological growth patterns of liver metastasis: updated consensus guidelines for pattern scoring, perspectives and recent mechanistic insights.

Targeting the IGF-Axis Potentiates Immunotherapy for Pancreatic Ductal Adenocarcinoma Liver Metastases by Altering the Immunosuppressive Microenvironment.

The unique immune microenvironment of liver metastases: Challenges and opportunities.

Liver metastases.

Aberrant MNK1/2 signaling as a mechanism involved in breast cancer liver metastasis.

Regulatory circuits controlling the immune microenvironment of liver metastases

An IGF-Trap for the treatment of breast cancer: consolidation of the pre-clinical profile and commercialization.

Montreal International Symposium on Angiogenesis and Metastasis 2011

Role of the microenvironment in liver metastasis

The CIHR/FRSQ Training Program in Cancer Research at McGill

The Role of Systemic Inflammation in Esophageal Cancer Metastasis: Exploring Neutrophil Dependent and Independent Mechanisms

Frequent collaborators

Peter Metrakos

Nathalie Lamarche-Vane

Julia Burnier

Alon Friedman

Rongtuan Lin

Jonathan Spicer

Danuta Radzioch

Nathalie Lamarche-Vane

Steven Gallinger

Moutih Rafei

Moutih Rafei

Sarkis Meterissian

Nada Jabado

Janusz Rak