This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.
Research
Latest papers
SC912 inhibits AR-V7 activity in castration-resistant prostate cancer by targeting the androgen receptor N-terminal domain.
Oncogene · 2024
Author Correction: Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Nature communications · 2024
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Nature communications · 2024
Latest funding
- $100,000
Development of RNA therapies against SARS-CoV-2, other coronaviruses and influenza viruses for pandemic preparedness
CIHR · 2023 · Principal investigator
- $50,000
COVID-19 Variant Supplement - Understand the high pathogenicity and zoonotic transmission of the COVID-19 virus: evasion of host innate immune responses
CIHR · 2021 · Co-investigator
- $50,000
Sex as a Biological Variable Supplement - Understand the high pathogenicity and zoonotic transmission of the COVID-19 virus: evasion of host innate immune responses
CIHR · 2020 · Co-investigator
66 publications.
SC912 inhibits AR-V7 activity in castration-resistant prostate cancer by targeting the androgen receptor N-terminal domain.
Yi Q, Han X, Yu HG, Chen HY, Qiu D, Su J, Lin R, Batist G, Wu JH
Author Correction: Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Kurmasheva N, Said A, Wong B, Kinderman P, Han X, Rahimic AHF, Kress A, Carter-Timofte ME, Holm E, van der Horst D, Kollmann CF, Liu Z, Wang C, Hoang HD, Kovalenko E, Chrysopoulou M, Twayana KS, Ottosen RN, Svenningsen EB, Begnini F, Kiib AE, Kromm FEH, Weiss HJ, Di Carlo D, Muscolini M, Higgins M, van der Heijden M, Arulanandam R, Bardoul A, Tong T, Ozsvar A, Hou WH, Schack VR, Holm CK, Zheng Y, Ruzek M, Kalucka J, de la Vega L, Elgaher WAM, Korshoej AR, Lin R, Hiscott J, Poulsen TB, O'Neill LA, Roy DG, Rinschen MM, van Montfoort N, Diallo JS, Farin HF, Alain T, Olagnier D
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Kurmasheva N, Said A, Wong B, Kinderman P, Han X, Rahimic AHF, Kress A, Carter-Timofte ME, Holm E, van der Horst D, Kollmann CF, Liu Z, Wang C, Hoang HD, Kovalenko E, Chrysopoulou M, Twayana KS, Ottosen RN, Svenningsen EB, Begnini F, Kiib AE, Kromm FEH, Weiss HJ, Di Carlo D, Muscolini M, Higgins M, van der Heijden M, Arulanandam R, Bardoul A, Tong T, Ozsvar A, Hou WH, Schack VR, Holm CK, Zheng Y, Ruzek M, Kalucka J, de la Vega L, Elgaher WAM, Korshoej AR, Lin R, Hiscott J, Poulsen TB, O'Neill LA, Roy DG, Rinschen MM, van Montfoort N, Diallo JS, Farin HF, Alain T, Olagnier D
Anthracyclines inhibit SARS-CoV-2 infection.
Wang Z, Pan Q, Ma L, Zhao J, McIntosh F, Liu Z, Ding S, Lin R, Cen S, Finzi A, Liang C
Discovery of a Small-Molecule Inhibitor Targeting the Androgen Receptor N-Terminal Domain for Castration-Resistant Prostate Cancer.
Yi Q, Liu W, Seo JH, Su J, Alaoui-Jamali MA, Luo J, Lin R, Wu JH
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation.
Xu Z, Choi JH, Dai DL, Luo J, Ladak RJ, Li Q, Wang Y, Zhang C, Wiebe S, Liu ACH, Ran X, Yang J, Naeli P, Garzia A, Zhou L, Mahmood N, Deng Q, Elaish M, Lin R, Mahal LK, Hobman TC, Pelletier J, Alain T, Vidal SM, Duchaine T, Mazhab-Jafari MT, Mao X, Jafarnejad SM, Sonenberg N
A newly identified interaction between nucleolar NPM1/B23 and the HTLV-I basic leucine zipper factor in HTLV-1 infected cells.
Liu Z, Larocque É, Xie Y, Xiao Y, Lemay G, Peloponese JM, Mesnard JM, Rassart É, Lin R, Zhou S, Zeng Y, Gao H, Cen S, Barbeau B
2-((1H-indol-3-yl)thio)-N-phenyl-acetamides: SARS-CoV-2 RNA-dependent RNA polymerase inhibitors.
Zhao J, Zhang G, Zhang Y, Yi D, Li Q, Ma L, Guo S, Li X, Guo F, Lin R, Luu G, Liu Z, Wang Y, Cen S
Mast cells-derived exosomes worsen the development of experimental cerebral malaria.
Huang K, Huang L, Zhang X, Zhang M, Wang Q, Lin H, Yu Z, Li X, Liu XB, Wu Q, Wang Y, Wang J, Jin X, Gao H, Han X, Lin R, Cen S, Liu Z, Huang B
Editorial: Sensing DNA in Antiviral Innate Immunity.
Lin R, Xing J, Zheng C
Development of RNA therapies against SARS-CoV-2, other coronaviruses and influenza viruses for pandemic preparedness
Principal investigators: Gatignol, Anne; Lin, Rongtuan
Keywords: Antiviral; Coronaviruses; Influenza Viruses; Innate Immunity; Ppp-Rnas; Sars-Cov-2; Sirnas
COVID-19 Variant Supplement - Understand the high pathogenicity and zoonotic transmission of the COVID-19 virus: evasion of host innate immune responses
Principal investigators: Liang, Chen
Keywords: Covid-19; Innate Immune Response; Interferon; Sars-Cov; Viral Pathogenicity; Zoonotic Transmission
Sex as a Biological Variable Supplement - Understand the high pathogenicity and zoonotic transmission of the COVID-19 virus: evasion of host innate immune responses
Principal investigators: Liang, Chen
Keywords: Covid-19.; Innate Immune Response; Interferon; Sars-Cov; Viral Pathogenicity; Zoonotic Transmission
Investigating the role of TRAF7 in regulating antiviral immune response
Principal investigators: Lin, Rongtuan
Keywords: Hsv-1; Influenza Virus; Innate Immunity; Interferons; Sting; Tamoxifen-Inducible Cre+/-Traf7flox/Flox Mice; Tbk1; Traf7; Ubiquitination; Virus Infection
Understand the high pathogenicity and zoonotic transmission of the COVID-19 virus: evasion of host innate immune responses
Principal investigators: Liang, Chen
Keywords: Covid-19; Innate Immune Response; Interferon; Sars-Cov; Viral Pathogenicity; Zoonotic Transmission
Repurposing of FDA-approved drugs as novel therapeutics for COVID-19
Principal investigators: Wu, Jian Hui
Keywords: Binding-Site Matching; Bret2 Assays; Covid-19; Drug Repurposing; In Silico Screening; Inhibitor Of Rbd/Ace2; Mpro Inhibitors; Plpro Inhibitors
Investigating the role of TRAF7 in regulating antiviral immune response
Principal investigators: Lin, Rongtuan
Keywords: Hsv1; Immunofluorescence; Influenza Virus; Innate Immune Response; S-Tag Purification Technique; Tamoxifen-Inducible Ko Mice; Tbk1; Traf7; Traf7flox/Flox Lys2-Cre Mice; Ubiquitination
Investigate the potential of Nrf2 modulators as antiviral and anticancer therapeutics
Principal investigators: Lin, Rongtuan
Keywords: Anti-Oxidative Response; Anti-Viral Innate Immunity; Apoptosis; Brusatol; Hsv-1; Murine Models; Nrf2 Transcription Factor; Oncolytic Viruses; Sirna Screening; Vsv
Development of novel pan-inhibitors of the androgen receptor variants as effective therapeutics for castration-resistant prostate cancer
Principal investigators: Wu, Jian Hui
Keywords: Androgen Receptor; Antiandrogen; Ar-V7; Castration-Resistant Prostate Cancer; N-Terminal Domain
Manipulating the immune response to inhibit Ebola virus infection
Principal investigators: Lin, Rongtuan; Qiu, Xiangguo
Keywords: 5'Ppp Rna; Adjuvant; Anti-Viral Innate Immunity; Cell-Specific Immune Responses; Ebola Glycoprotein; Ebola Virus; Interferons; Mouse Model; Rig-I Signaling; Vaccine
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medicine
- Oncology
- Biochemistry, Microbiology and Immunology
- Biochemistry
- AIDS Pathogenesis Unit
- Research Centre
- Surgery
- Other
Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Tommy Alain
Biochemistry, Microbiology and Immunology
4 shared papers, latest 2024
Pnina Brodt
Surgery
2 shared papers, latest 2015
Chen Liang
AIDS Pathogenesis Unit
2 shared papers, latest 2023
Jean-Simon Diallo
Biochemistry, Microbiology and Immunology
2 shared papers, latest 2024
Nahum Sonenberg
Biochemistry
2 shared papers, latest 2022
Nathalie Grandvaux
Research Centre
2 shared papers, latest 2005
Kevin Petrecca
Engineering Physics
1 shared papers, latest 2021
Morag Park
Oncology
1 shared papers, latest 2021
Jerry Pelletier
Biochemistry
1 shared papers, latest 2022
Ivan Topisirovic
Lady Davis Institute for Medical Research
1 shared papers, latest 2021
Mark Basik
Social Studies of Medicine
1 shared papers, latest 2021
Michael Pollak
Oncology
1 shared papers, latest 2021
Kevin Petrecca
Neurology and Neurosurgery
1 shared papers, latest 2021
Salman Qureshi
Medicine
1 shared papers, latest 2013
Julie St-Pierre
Biochemistry, Microbiology and Immunology
1 shared papers, latest 2021
Ivan Topisirovic
Faculty
1 shared papers, latest 2021
Morag Park
Oncology
1 shared papers, latest 2021
Anne Gatignol
Medicine
1 shared papers, latest 2005
Jean-Pierre Routy
Microbiology and Immunology
1 shared papers, latest 2014
Thomas Duchaine
Biochemistry
1 shared papers, latest 2022
Andrew Smith
Management Science
1 shared papers, latest 2013
Gerald Batist
Medicine
1 shared papers, latest 2024
Gerald Batist
Chemical Engineering
1 shared papers, latest 2024
Michael Witcher
Oncology
1 shared papers, latest 2021
Jean-Pierre Routy
Medicine
1 shared papers, latest 2014
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