This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
The Influence of Arginine Methylation in Immunity and Inflammation.
Journal of inflammation research · 2022 · senior author
Sam68 promotes hepatic gluconeogenesis via CRTC2.
Nature communications · 2021
Genetic evidence for partial redundancy between the arginine methyltransferases CARM1 and PRMT6.
The Journal of biological chemistry · 2020
Latest funding
- $1,063,350
Epigenetic modulation to enhance CD8+ T cells for improved antitumor activity.
CIHR · 2024 · Nominated PI
- $1,291,972
Arginine methylation of the RNA helicase DDX5 in the regulation of RNA/DNA hybrids during the DNA damage response.
CIHR · 2023 · Nominated PI
- $309,250
Errant epitopes from arginine methylated SARS-CoV-2 proteins predisposing to autoimmune diseases.
CIHR · 2021 · Nominated PI
8 publications.
The Influence of Arginine Methylation in Immunity and Inflammation.
Srour N, Khan S, Richard S
Sam68 promotes hepatic gluconeogenesis via CRTC2.
Qiao A, Zhou J, Xu S, Ma W, Boriboun C, Kim T, Yan B, Deng J, Yang L, Zhang E, Song Y, Ma YC, Richard S, Zhang C, Qiu H, Habegger KM, Zhang J, Qin G
Genetic evidence for partial redundancy between the arginine methyltransferases CARM1 and PRMT6.
Cheng D, Gao G, Di Lorenzo A, Jayne S, Hottiger MO, Richard S, Bedford MT
Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response.
Szewczyk MM, Ishikawa Y, Organ S, Sakai N, Li F, Halabelian L, Ackloo S, Couzens AL, Eram M, Dilworth D, Fukushi H, Harding R, Dela Seña CC, Sugo T, Hayashi K, McLeod D, Zepeda C, Aman A, Sánchez-Osuna M, Bonneil E, Takagi S, Al-Awar R, Tyers M, Richard S, Takizawa M, Gingras AC, Arrowsmith CH, Vedadi M, Brown PJ, Nara H, Barsyte-Lovejoy D
Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response.
Szewczyk MM, Ishikawa Y, Organ S, Sakai N, Li F, Halabelian L, Ackloo S, Couzens AL, Eram M, Dilworth D, Fukushi H, Harding R, Dela Seña CC, Sugo T, Hayashi K, McLeod D, Zepeda C, Aman A, Sánchez-Osuna M, Bonneil E, Takagi S, Al-Awar R, Tyers M, Richard S, Takizawa M, Gingras AC, Arrowsmith CH, Vedadi M, Brown PJ, Nara H, Barsyte-Lovejoy D
Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation.
Infantino S, Light A, O'Donnell K, Bryant V, Avery DT, Elliott M, Tangye SG, Belz G, Mackay F, Richard S, Tarlinton D
p38 Mitogen-Activated Protein Kinase Pathway Regulates Genes during Proliferation and Differentiation in Oligodendrocytes.
Haines JD, Fulton DL, Richard S, Almazan G
Arginine methylation of the histone H3 tail impedes effector binding.
Iberg AN, Espejo A, Cheng D, Kim D, Michaud-Levesque J, Richard S, Bedford MT
Epigenetic modulation to enhance CD8+ T cells for improved antitumor activity.
Principal investigators: Richard, Stéphane
Keywords: Arginine Methylation; Cd8+ T Cells; Cytotoxic; Dna Methylation; Dnmt3a; Immunotherapy; Melanoma; Prmt7; Protac Inhibitor; Rna Sequencing
Arginine methylation of the RNA helicase DDX5 in the regulation of RNA/DNA hybrids during the DNA damage response.
Principal investigators: Richard, Stéphane
Keywords: Arginine Methylation; Breast Cancer; Dna Damage Signaling; Dna/Rna Hybrids Or R-Loops; Double Stranded Dna Break; Homologous Recombination; Nhej; Pdx Mouse Models; Rna Helicases; Triple Negative Breast Cancers
Errant epitopes from arginine methylated SARS-CoV-2 proteins predisposing to autoimmune diseases.
Principal investigators: Richard, Stéphane
Keywords: Antigenic Epitopes; Arginine Methylation; Nucleocapsid; Post-Translational Modification; Prmt Inhibitors; Prmt1; Variants; Viral Replication
Arsenic 3 methyltransferase: a role in arsenic-induced atherosclerosis and beyond?
Principal investigators: Mann, Koren K
Keywords: Arsenic; Atherosclerosis; Methyltransferase; Toxicology
Title: Epigenetic regulation of oligodendrocyte function and CNS myelination.
Principal investigators: Richard, Stéphane
Keywords: Arginine Methylation; Growth Factor Receptor; Myelination; Oligodendrocytes; Post-Translational Modifications; Prmt5
Molecular and Genetic Analysis of Arginine Methylation and RNA Binding proteins in Health and Disease.
Principal investigators: Richard, Stéphane
Keywords: Cancer; Chromatin; Dna Damage Signaling; Dna Repair; Genomic Instability; Post-Translational Modifications; Protein-Protein Interactions; Rna Binding Proteins; Rna Splicing; Signal Transduction
The identification of alternatively spliced genes by the Quaking RNA binding proteins in oligodendrocytes
Principal investigators: Darbelli, Lama
Keywords: Alternative Splicing; Axons Maintenance; Multiple Sclerosis; Oligodendrocytes And Myelination; Post-Transcriptional Regulation; Rna Biology
Defining the role of protein arginine methyltransferases (PRMTs) and RGG/RG motifs in cancer and in the maintenance of genomic stability.
Principal investigators: Richard, Stéphane
Keywords: Arginine Methylation; Cancer; Cell Cycle Control; Conditional Knockout Mice; Dna Damage Response; Genomic Instability
The role of the Sam68 RNA binding protein in normal and diseased cells.
Principal investigators: Richard, Stéphane
Keywords: Alternative Splicing; Breast Cancer; Cell Adhesion; Cell Proliferation; Colon Cancer; Lung Cancer; P53; Ras; Rna Binding Proteins; Sam68
The role of post-translational modifications of MRE11 in mediating the DNA damage response.
Principal investigators: Richard, Stéphane
Keywords: Arginine Methylation; Dna Damage Signalling; Gar Motif; Genetics; Mre11; Sumoylation
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medicine/Oncology
- Pharmacologie - Physiologie
- Department of Molecular Genetics
- Pharmacology and Toxicology
- Other
Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Stéphane Richard
Pharmacologie - Physiologie
5 shared papers, latest 2021
Anne-Claude Gingras
Department of Molecular Genetics
2 shared papers, latest 2020
Dalia Barsyte-Lovejoy
Pharmacology and Toxicology
2 shared papers, latest 2020
Rachel Harding
Faculty
2 shared papers, latest 2020
Ahmed Aman
Faculty
2 shared papers, latest 2020
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